TWAS hub - C6orf106

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.2930	0.0570	0.0e+00	0.209	0.228	0.230	0.232	0.218	5.4e-25	2.8e-27	1.2e-27	6.9e-28	4.0e-26
2	GTEx	Artery Tibial	0.0750	0.0358	3.4e-03	0.025	NA	0.015	NA	0.021	4.6e-03	NA	2.1e-02	NA	8.7e-03
3	GTEx	Brain Cortex	0.2180	0.0730	8.0e-04	0.074	NA	0.099	NA	0.091	4.4e-03	NA	1.1e-03	NA	1.8e-03
4	GTEx	Cells EBV-transformed lymphocytes	0.1970	0.0760	5.6e-03	0.004	NA	-0.005	NA	0.002	2.3e-01	NA	4.9e-01	NA	2.7e-01
5	GTEx	Colon Transverse	0.1480	0.0660	7.5e-03	0.045	NA	-0.003	NA	0.029	3.3e-03	NA	4.5e-01	NA	1.6e-02
6	GTEx	Muscle Skeletal	0.0821	0.0346	1.7e-04	0.059	NA	0.059	NA	0.064	1.7e-06	NA	1.9e-06	NA	7.1e-07
7	GTEx	Nerve Tibial	0.1082	0.0447	3.4e-03	0.071	NA	0.069	NA	0.063	9.1e-06	NA	1.3e-05	NA	2.9e-05
8	GTEx	Pancreas	0.1410	0.0550	2.6e-03	0.113	NA	0.134	NA	0.124	1.7e-05	NA	2.8e-06	NA	7.0e-06
9	GTEx	Skin Sun Exposed Lower leg	0.0850	0.0360	1.9e-03	0.045	NA	0.023	NA	0.018	1.2e-04	NA	4.6e-03	NA	1.1e-02
10	GTEx	Thyroid	0.0940	0.0410	8.3e-03	0.005	NA	0.005	NA	0.001	1.2e-01	NA	1.1e-01	NA	2.6e-01
11	METSIM	Adipose	0.0402	0.0184	6.1e-04	0.022	0.018	0.010	0.017	0.018	2.8e-04	7.7e-04	9.1e-03	1.1e-03	8.6e-04
12	NTR	Blood	0.0278	0.0103	4.6e-05	0.022	0.011	0.015	0.016	0.019	1.1e-07	1.1e-04	1.1e-05	5.8e-06	7.2e-07
13	ROSMAP	Brain Pre-frontal Cortex	0.3006	0.0460	0.0e+00	0.265	0.323	0.320	0.331	0.319	6.3e-34	1.4e-42	5.1e-42	9.3e-44	5.7e-42
14	TCGA	Head and Neck Squamous Cell Carcinoma	0.0868	0.0459	6.5e-05	0.028	0.043	0.042	NA	0.048	3.8e-04	1.3e-05	1.5e-05	NA	3.6e-06
15	TCGA	Kidney Renal Clear Cell Carcinoma	0.0352	0.0234	9.5e-03	0.008	0.010	0.003	NA	0.006	3.9e-02	2.4e-02	1.2e-01	NA	5.9e-02
16	TCGA	Brain Lower Grade Glioma	0.0443	0.0190	6.4e-06	0.050	0.029	0.033	NA	0.034	2.4e-06	3.0e-04	1.1e-04	NA	8.1e-05
17	TCGA	Lung Adenocarcinoma	0.0317	0.0192	2.4e-03	0.027	0.009	0.012	NA	0.014	3.6e-04	2.6e-02	1.3e-02	NA	7.6e-03
18	TCGA	Ovarian Serous Cystadenocarcinoma	0.1400	0.0590	3.3e-04	0.069	0.035	0.057	NA	0.046	2.0e-05	2.0e-03	1.0e-04	NA	4.2e-04
19	TCGA	Thyroid Carcinoma	0.0770	0.0390	8.6e-04	0.005	0.040	0.046	NA	0.025	1.1e-01	9.2e-05	2.5e-05	NA	1.5e-03

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19
Weight	35.4	174.0	302.8	14.1	0.7	14.1	12.9	13.0	-14.7	15.8	15.8	8.9	12.1	11.6	17.4	14.8	2.4	14.7	17.2	13.5	14.8	7.5
Basal metabolic rate	35.4	195.7	327.6	14.9	3.5	15.1	13.0	13.3	-14.3	17.0	16.0	11.3	13.0	12.0	18.1	16.0	4.2	15.8	17.7	14.1	16.3	9.6
Arm predicted mass (right)	34.6	176.8	282.2	13.8	4.5	14.4	12.6	12.6	-13.1	16.3	15.0	11.7	12.6	11.1	16.8	15.2	4.4	15.1	16.5	13.4	15.4	9.7
Arm fat-free mass (right)	34.3	175.6	278.9	13.8	4.5	14.4	12.5	12.6	-13.0	16.3	14.8	11.8	12.4	11.2	16.7	15.1	4.6	15.0	16.4	13.4	15.3	9.8
Arm fat-free mass (left)	34.3	173.8	275.6	13.8	4.2	14.1	12.7	12.4	-13.2	16.1	14.9	11.4	12.4	11.2	16.6	15.1	4.5	15.1	16.4	13.2	15.4	9.2
Arm predicted mass (left)	33.9	172.5	275.6	13.7	3.9	14.2	12.6	12.4	-13.3	16.0	14.8	11.3	12.3	11.4	16.6	14.9	4.2	15.0	16.4	13.2	15.4	8.9
Whole body fat-free mass	33.8	193.3	316.8	14.7	4.6	15.0	12.7	13.0	-13.7	17.0	15.6	11.9	13.0	11.8	17.8	15.9	5.0	15.8	17.4	13.9	16.4	10.1
Whole body water mass	33.6	191.5	316.8	14.6	4.5	15.0	12.7	12.9	-13.6	16.9	15.5	11.8	12.9	11.8	17.8	15.8	4.8	15.8	17.3	13.8	16.4	9.9
Hip circumference	32.5	140.1	246.5	12.8	-1.6	11.8	12.7	12.3	-14.8	13.6	15.0	6.9	10.3	9.9	15.7	12.9	1.0	13.5	15.6	11.8	12.7	4.6
Leg fat-free mass (left)	32.4	171.4	299.3	13.9	2.2	14.2	12.3	12.5	-14.0	15.6	15.4	9.8	12.2	11.3	17.3	14.8	3.0	14.8	16.9	13.0	15.3	8.2
Trunk predicted mass	32.4	184.9	292.4	14.3	5.9	14.6	12.1	12.5	-12.6	16.8	14.7	12.6	12.9	11.6	17.1	15.7	5.7	15.5	16.6	13.4	16.2	10.6
Trunk fat-free mass	32.3	185.5	295.8	14.3	5.9	14.6	12.1	12.5	-12.6	16.8	14.7	12.7	12.9	11.6	17.2	15.7	5.7	15.6	16.6	13.4	16.2	10.7
Leg predicted mass (left)	32.1	169.9	297.2	13.9	2.2	14.1	12.3	12.4	-13.9	15.5	15.3	9.7	12.1	11.3	17.2	14.8	3.1	14.7	16.9	13.0	15.2	8.1
Leg fat-free mass (right)	31.9	170.3	295.8	13.9	2.6	14.3	12.1	12.4	-13.7	15.6	15.2	9.8	12.2	11.3	17.2	14.8	3.3	14.7	16.8	13.0	15.3	8.3
Leg predicted mass (right)	31.8	169.7	295.7	13.9	2.5	14.2	12.1	12.3	-13.7	15.6	15.2	9.8	12.2	11.2	17.2	14.7	3.3	14.7	16.8	13.0	15.3	8.3
Height	26.8	517.0	846.8	23.7	17.7	25.6	13.9	18.7	-14.1	28.5	21.9	21.9	19.8	13.7	29.1	27.9	16.0	25.8	26.8	19.6	27.6	28.1
Trunk fat mass	26.4	113.2	201.6	11.6	-1.2	11.5	10.5	11.3	-12.4	12.6	13.0	5.4	9.5	9.3	14.2	11.7	1.4	11.5	14.2	11.2	11.3	5.6
Standing height	26.2	260.3	404.0	17.1	12.9	17.7	10.0	13.3	-10.1	20.1	15.5	16.0	13.6	10.4	20.0	20.1	12.5	18.5	18.6	14.0	19.1	19.8
Whole body fat mass	24.5	102.3	182.2	10.8	-1.8	10.6	10.4	10.7	-12.3	11.9	12.6	5.0	9.0	9.0	13.4	10.9	0.8	11.0	13.5	10.8	10.5	4.6
Leg fat mass (left)	23.7	92.4	161.3	10.0	-2.4	9.8	10.5	10.0	-12.3	11.1	12.1	5.0	8.8	8.8	12.4	10.1	0.2	10.5	12.7	10.3	9.9	3.3
Leg fat mass (right)	23.2	90.1	158.8	9.9	-2.5	9.6	10.2	9.9	-12.1	11.0	12.0	4.9	8.6	8.8	12.4	10.0	-0.1	10.3	12.6	10.1	9.8	3.3
Arm fat mass (left)	22.6	93.0	166.4	10.1	-2.6	9.8	10.3	10.0	-12.3	11.1	12.1	4.7	8.7	8.9	12.7	10.1	-0.2	10.4	12.9	10.2	10.3	3.1
Forced expiratory volume in 1-second (FEV1), predicted	21.0	43.6	71.2	7.2	6.1	7.1	3.1	5.9	-3.2	8.4	5.8	7.8	6.7	5.1	7.5	8.3	4.7	6.9	6.8	6.4	7.0	8.2
Arm fat mass (right)	20.8	85.5	153.8	9.7	-2.9	9.3	10.0	9.6	-12.0	10.5	11.7	4.2	8.3	8.6	12.2	9.6	-0.4	10.0	12.4	9.7	9.8	2.6
Waist circumference	18.9	69.3	118.8	8.3	-1.7	9.7	8.8	8.9	-9.8	9.7	9.9	4.8	7.7	8.7	10.8	8.4	-0.1	8.7	10.9	8.5	9.4	2.8
Comparative height size at age 10	16.5	90.8	169.0	9.7	8.3	10.7	5.9	8.1	-5.5	11.8	9.2	9.6	7.3	5.2	11.8	12.3	7.1	11.0	10.7	7.3	11.1	13.0
Trunk fat percentage	14.9	59.8	112.4	8.3	-3.1	8.1	8.0	8.6	-9.9	8.7	10.1	2.1	6.4	6.5	10.5	8.2	-0.2	8.1	10.6	8.2	7.6	2.9
Sitting height	14.9	105.6	185.0	10.5	5.6	11.9	8.3	9.1	-7.5	12.9	9.5	8.8	9.7	7.6	13.3	11.5	5.8	11.7	12.7	9.8	13.6	10.3
BMI	13.4	77.5	169.0	8.6	-6.8	8.0	10.5	9.5	-13.0	8.8	11.0	2.2	8.1	9.8	10.8	7.0	-4.5	8.2	11.4	9.9	8.1	-2.5
Body fat percentage	13.4	52.9	97.8	7.7	-3.8	7.2	8.0	8.2	-9.9	8.1	9.6	1.7	6.0	6.3	9.6	7.4	-0.7	7.6	9.9	7.9	6.8	1.8
Body mass index (BMI)	12.2	52.0	116.6	6.9	-5.3	6.7	8.9	7.5	-10.8	7.3	9.4	2.0	6.5	7.4	9.0	6.2	-3.3	6.9	9.4	7.8	6.7	-1.3
HDL Cholesterol	12.0	20.0	39.2	-5.3	0.5	-4.0	-3.5	-3.8	4.6	-5.5	-4.7	-1.9	-5.7	-6.0	-6.3	-4.3	1.2	-3.8	-5.7	-5.8	-4.6	-1.2
Arm fat percentage (left)	10.7	42.8	91.6	6.5	-5.0	6.0	7.6	7.2	-9.6	6.7	8.6	0.7	5.5	6.1	8.6	6.0	-1.9	6.5	8.9	6.8	6.3	-0.1
LDL Cholesterol	10.5	16.5	30.3	-5.2	-2.2	-5.4	-2.5	-4.5	2.5	-5.5	-3.5	-3.1	-4.8	-4.0	-4.7	-3.9	-1.3	-3.7	-4.2	-5.4	-3.9	-3.8
Leg fat percentage (left)	10.5	38.0	84.7	6.0	-4.6	5.5	7.5	6.6	-9.2	6.5	8.3	1.2	5.2	5.6	7.8	5.8	-1.6	6.3	8.2	6.8	5.3	0.3
Leg fat percentage (right)	10.0	36.3	80.1	5.9	-4.5	5.2	7.2	6.5	-8.9	6.3	8.3	1.3	5.0	5.6	7.7	5.8	-1.7	6.1	8.0	6.6	5.2	0.4
Arm fat percentage (right)	9.9	39.2	87.6	6.3	-5.1	5.5	7.2	6.8	-9.4	6.3	8.3	0.6	5.2	6.0	8.2	5.7	-2.0	6.3	8.5	6.4	6.0	-0.6
Medication: Omeprazole	9.2	11.0	19.7	3.9	-0.4	3.4	3.8	3.3	-4.0	3.8	3.8	1.9	3.3	3.7	4.4	3.2	-1.2	3.1	4.4	3.3	3.5	1.1
Relative age of first facial hair	8.8	18.1	30.9	5.6	2.8	4.7	2.9	3.5	-3.2	5.4	4.0	4.0	4.2	2.6	5.0	5.2	2.5	4.6	4.9	4.5	3.9	5.2
Allergy or Eczema	8.6	22.6	34.7	-5.4	-2.2	-4.3	-3.8	-2.4	4.4	-5.7	-4.9	-5.1	-5.7	-5.5	-5.8	-5.4	-2.4	-5.7	-5.5	-4.8	-5.9	-2.3
Back pain experienced in last month	8.4	12.2	21.3	4.6	1.1	2.8	2.9	3.2	-3.2	4.3	4.1	2.4	4.5	4.1	4.3	3.7	0.5	3.3	4.3	4.2	3.5	2.2
Forced expiratory volume in 1-second (FEV1)	8.1	27.3	65.6	5.3	6.2	4.0	2.8	4.8	-2.3	6.4	5.2	7.3	3.1	2.4	5.8	7.5	3.7	5.6	5.0	3.9	4.6	8.1
Forced expiratory volume in 1-second (FEV1), Best measure	7.9	25.2	67.6	5.0	6.6	3.5	2.2	4.0	-1.9	6.0	4.7	7.3	3.1	2.5	5.4	7.4	3.9	5.4	4.5	3.4	4.4	8.2
Overall health rating	7.8	16.8	29.9	5.0	-0.3	4.5	4.2	3.1	-4.6	5.2	4.4	2.3	4.1	4.3	4.9	3.8	-0.8	4.4	5.5	4.8	4.8	1.1
Stomach or abdominal pain in last month	7.6	9.5	14.6	3.7	0.7	2.9	3.8	3.0	-3.5	3.5	3.7	2.2	3.2	2.2	3.7	3.6	-1.0	3.2	3.7	3.2	3.2	1.2
Hayfever, allergic rhinitis or eczema	7.4	16.0	25.6	-4.3	-2.6	-3.5	-3.2	-2.1	3.3	-4.8	-4.0	-4.5	-4.7	-4.1	-4.6	-4.6	-2.6	-5.1	-4.5	-4.0	-4.9	-2.5
Blood Platelet Count	7.3	84.9	179.6	-8.3	1.9	-10.6	-13.0	-8.6	13.4	-9.7	-11.6	-4.8	-8.1	-3.2	-11.5	-8.8	-0.1	-11.2	-12.4	-9.5	-10.0	-0.7
Medication for pain relief, constipation, heartburn	7.3	12.5	24.7	-4.7	0.4	-4.0	-3.8	-3.0	4.6	-3.8	-4.2	-1.8	-3.2	-5.0	-4.1	-3.5	1.2	-3.3	-4.4	-3.5	-3.5	0.4
Coronary Artery Disease (CAD)	7.1	8.5	20.0	3.3	-1.0	3.2	3.6	3.6	-3.5	2.8	2.6	1.8	3.4	4.5	3.1	2.2	-0.1	2.5	3.4	3.4	2.8	-0.7
Myopia	7.0	10.1	16.9	-3.9	-2.3	-1.6	-3.4	-2.0	3.0	-4.1	-3.5	-3.3	-3.5	-2.0	-3.9	-4.0	-0.0	-3.6	-3.8	-3.2	-3.3	-2.6
Medication: Omeprazole (e.g. Zanprol)	7.0	8.5	17.1	3.3	-0.4	3.0	3.2	2.9	-3.3	3.3	3.3	1.2	2.9	3.4	4.1	2.8	-1.3	2.7	3.8	2.6	3.2	1.5
Heart attack/myocardial infarction (self-reported)	6.9	8.9	18.4	4.3	1.6	2.8	2.8	2.3	-3.5	3.4	3.3	2.9	1.7	2.8	3.6	3.8	0.8	3.6	3.8	2.4	2.2	2.6
Heart attack	6.8	8.7	17.9	4.2	1.6	2.8	2.6	2.2	-3.4	3.3	3.2	2.8	1.9	2.9	3.7	3.7	0.5	3.5	3.8	2.4	2.4	2.6
Allergy	6.8	15.6	26.0	4.2	2.5	3.4	3.1	2.7	-3.0	4.9	4.0	4.3	5.1	4.2	4.8	4.5	1.4	4.5	4.4	4.5	4.7	2.6
Pulse rate, automated reading	6.7	21.7	45.0	-5.4	0.0	-4.2	-4.3	-4.3	5.9	-5.3	-5.7	-1.8	-4.7	-4.4	-6.7	-5.4	-0.9	-5.0	-6.1	-5.2	-4.7	-1.7
Health satisfaction	6.5	8.4	17.2	3.4	0.0	2.7	3.4	1.8	-3.4	3.4	3.4	1.5	2.6	2.2	3.5	2.9	0.2	3.7	3.9	3.1	4.2	0.9
Forced vital capacity (FVC)	6.3	24.1	68.6	4.5	6.4	4.6	2.1	3.7	-1.5	5.8	4.4	7.1	2.2	1.1	5.2	6.9	4.4	5.5	4.6	2.9	4.9	8.3
Hand grip strength (right)	6.2	16.8	37.9	4.5	4.9	2.9	2.8	4.0	-1.8	5.0	3.8	5.2	3.7	1.3	4.5	5.6	2.5	4.3	4.0	3.8	3.7	6.2
Number of operations (self-reported)	6.1	9.0	14.8	3.3	0.9	2.3	3.6	2.4	-3.1	3.8	2.9	3.3	3.1	2.9	3.2	3.2	2.1	3.8	3.2	3.4	3.1	2.1
Pain experienced in last month	6.1	10.2	16.7	-4.0	-0.0	-2.8	-4.1	-2.7	3.8	-3.6	-3.7	-1.7	-3.9	-3.7	-3.6	-3.1	0.8	-3.2	-3.9	-3.5	-3.5	0.4
Length of working week for main job	6.0	6.7	12.2	2.8	-0.1	2.1	3.5	3.2	-3.2	2.6	2.8	2.1	3.0	3.1	2.8	2.3	-0.8	2.8	2.7	2.6	3.0	-0.3
Forced vital capacity (FVC), Best measure	5.9	21.5	67.1	4.0	6.8	3.9	1.6	3.0	-1.0	5.3	3.6	7.1	2.3	1.5	4.6	6.5	4.5	5.2	3.9	2.4	4.6	8.2
Chest pain or discomfort	5.8	8.3	13.5	3.7	1.7	2.6	3.3	2.3	-3.5	3.3	3.6	3.1	2.1	2.4	3.4	3.7	-0.0	3.5	3.3	2.2	2.7	1.9
Leg pain on walking	5.8	7.3	13.3	3.0	-0.0	2.7	3.6	1.8	-3.4	3.2	2.7	2.2	3.0	2.9	3.0	2.2	-0.6	2.7	3.3	3.5	2.9	-1.1
Shortness of breath walking on level ground	5.7	6.8	13.8	3.3	-0.9	2.1	3.4	1.7	-3.7	2.9	3.5	1.2	1.9	2.3	3.3	2.8	-0.3	3.0	3.5	2.9	2.2	0.8
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	5.7	6.7	15.2	3.6	0.8	3.1	1.9	3.0	-2.4	2.7	2.7	1.6	3.0	3.9	3.4	2.7	-0.8	1.9	3.0	2.4	2.4	1.2
Unable to work because of sickness or disability	5.7	7.3	15.5	2.8	-1.6	2.5	3.5	2.5	-3.9	2.8	3.3	0.5	2.7	2.1	3.3	2.3	-0.8	3.3	3.6	2.8	2.9	-0.7
Exposure to tobacco smoke at home	5.5	6.2	19.5	2.1	-1.7	1.9	4.4	1.2	-4.4	2.0	3.6	1.6	1.6	1.2	2.4	2.5	1.4	3.4	2.9	2.1	1.9	-0.9
Bipolar Disorder (2011)	5.4	5.2	11.4	3.0	1.2	2.2	2.5	0.0	-2.1	3.1	3.3	2.6	0.7	0.8	2.4	3.2	0.8	2.8	2.4	0.0	1.4	3.4
Peak expiratory flow (PEF)	5.3	12.3	32.2	3.7	4.2	2.1	1.4	3.4	-1.0	4.5	3.2	4.6	3.0	2.5	3.4	4.9	2.8	3.6	3.1	3.1	2.8	5.7
Medication for cholesterol	5.3	8.0	20.1	-3.4	-0.8	-2.9	-3.1	-2.5	2.7	-2.9	-2.5	-3.0	-3.1	-4.5	-3.4	-2.7	-0.3	-3.0	-3.1	-1.8	-3.5	-1.0
Waist Hip Ratio (WHR)	5.2	23.2	66.6	-5.5	2.2	-2.0	-6.2	-4.4	8.2	-4.3	-7.3	-0.8	-4.2	-1.3	-6.4	-5.2	0.5	-6.1	-6.5	-4.8	-4.0	-0.0
Nervous feelings	5.2	9.8	15.5	-3.5	-1.1	-3.0	-3.4	-3.6	3.6	-3.6	-3.5	-2.8	-2.1	-3.2	-3.8	-3.9	-2.5	-3.6	-3.4	-2.6	-2.8	-1.8
Smoking Status	5.1	12.2	23.8	3.9	-0.5	3.4	4.2	2.4	-4.7	3.6	3.7	2.0	3.6	4.9	4.1	3.2	1.2	4.2	4.3	3.0	4.3	0.0
Lung FEV1/FVC ratio	5.0	25.2	44.5	6.2	2.7	2.7	3.6	5.8	-4.1	6.2	5.9	4.8	6.4	5.9	6.1	6.7	0.2	4.3	5.1	5.7	3.1	4.7
Ever had hysterectomy (womb removed)	5.0	5.7	8.9	2.8	1.9	1.2	2.7	1.3	-2.2	2.9	2.2	2.4	2.1	3.0	2.4	3.0	1.6	3.0	2.4	1.8	2.6	2.6
Impedance of leg (right)	4.8	23.3	48.3	-4.4	2.6	-4.8	-5.9	-4.3	7.0	-4.8	-5.4	-2.1	-4.9	-5.7	-6.0	-3.3	2.6	-4.4	-6.4	-5.1	-5.8	2.1
Seen doctor (GP) for nerves, anxiety, tension or depression	4.8	7.3	15.9	-3.1	-1.7	-2.1	-2.9	-2.2	2.9	-3.1	-3.5	-2.7	-1.8	-2.0	-3.1	-4.0	-1.6	-3.6	-2.8	-1.5	-2.2	-2.7
Knee pain experienced in last month	4.8	7.4	21.5	2.8	-0.4	2.2	4.6	2.2	-3.4	3.0	3.0	1.7	2.8	2.3	2.7	2.5	-1.1	3.1	3.3	2.6	3.6	-1.2
Medication: Ramipril	4.7	6.0	16.5	3.2	0.6	3.3	2.7	3.1	-2.4	2.9	1.7	3.2	1.9	4.1	2.2	2.1	0.3	1.9	2.4	2.2	2.1	0.6
Exposure to tobacco smoke outside home	4.6	6.1	10.7	2.8	0.8	2.2	3.2	1.9	-2.8	2.9	3.0	2.0	2.0	2.3	2.6	3.1	1.6	3.3	2.7	2.6	2.1	1.6
Impedance of leg (left)	4.5	21.7	46.7	-4.1	2.9	-4.3	-5.7	-4.2	6.8	-4.4	-5.3	-1.9	-4.6	-5.6	-5.9	-3.0	3.0	-4.1	-6.1	-4.7	-5.6	2.5
Smoking status: Current	4.5	7.1	12.2	2.9	0.1	2.8	2.8	1.4	-3.2	2.9	3.1	1.2	3.2	3.5	3.2	2.8	1.5	3.2	3.2	3.0	2.6	0.4
Worry (Nagel 2018)	4.1	8.5	17.2	-3.0	0.1	-3.0	-4.2	-3.9	4.1	-2.8	-3.7	-2.6	-0.6	-2.1	-3.4	-3.6	-2.2	-3.6	-3.1	-1.8	-1.7	-1.7
Medication: Blood pressure	4.1	7.8	28.3	3.3	-0.4	3.2	2.9	2.3	-3.0	2.5	2.5	1.8	3.5	5.3	3.5	2.3	-0.7	2.2	3.2	1.8	3.4	-0.4
Pain type(s) experienced in last month: Hip pain	4.1	5.2	11.4	3.4	0.2	1.9	3.1	2.3	-3.0	2.5	2.6	1.7	1.4	2.3	2.8	2.1	-0.8	2.0	3.0	2.2	2.3	0.1
Impedance of whole body	4.1	20.8	43.0	-3.9	2.1	-4.0	-6.1	-4.3	6.6	-4.6	-4.9	-3.2	-4.8	-6.1	-5.1	-3.0	2.7	-4.1	-5.5	-5.0	-5.1	2.2
Average weekly spirits intake	4.0	4.9	15.1	2.3	-0.1	3.9	2.2	2.2	-2.4	2.5	1.6	2.0	3.0	2.7	1.7	1.6	-0.8	2.1	2.3	2.9	2.0	0.2
Relative age voice broke	4.0	6.1	12.5	3.1	1.9	2.0	1.7	2.9	-1.3	3.1	2.4	2.2	2.4	1.0	2.8	3.4	2.2	2.7	2.5	2.4	2.0	3.5
Hand grip strength (left)	3.9	10.2	25.7	3.4	3.8	1.4	2.2	3.5	-1.3	3.8	3.0	4.0	2.6	0.1	3.6	4.6	2.2	3.6	2.9	2.5	3.0	5.1
Long-standing illness, disability or infirmity	3.9	5.9	12.2	2.8	-0.7	2.5	2.2	1.1	-2.8	2.9	2.5	1.0	2.6	3.5	2.9	2.2	1.0	3.0	3.2	2.8	2.6	0.1
Age when periods started (menarche)	3.8	9.2	18.4	4.3	2.2	3.2	2.1	2.2	-2.5	3.8	2.8	2.9	3.5	3.4	3.6	3.3	0.4	2.8	3.8	3.7	3.1	1.5
Medication: Aspirin	3.8	5.0	11.7	2.5	-0.7	1.9	2.9	2.5	-3.4	1.7	3.0	1.5	1.7	2.8	2.8	2.8	-0.7	2.4	2.5	0.9	1.8	-0.4
Emphysema/chronic bronchitis	3.7	4.2	7.7	2.5	-0.7	2.5	2.2	2.3	-2.5	1.9	2.3	0.5	1.9	1.9	2.8	1.9	-0.3	2.3	2.7	1.8	2.5	0.2
Current tobacco smoking	3.6	5.8	10.7	2.6	0.0	2.6	2.7	1.2	-2.9	2.7	2.7	1.0	3.0	3.3	2.8	2.5	1.2	2.9	2.9	3.0	2.2	0.1
Impedance of arm (right)	3.6	16.6	34.7	-3.2	1.1	-4.0	-5.9	-4.0	5.5	-4.4	-4.3	-3.8	-4.8	-5.3	-4.0	-2.6	2.5	-3.4	-4.4	-5.0	-4.0	1.4
Lung FVC	3.5	17.9	34.4	-5.1	0.8	-4.2	-4.3	-3.7	4.8	-4.9	-4.2	-0.5	-5.9	-4.4	-5.4	-3.7	-1.1	-4.2	-5.7	-5.0	-4.9	-1.2
Worrier / anxious feelings	3.5	6.6	15.5	-2.8	-0.5	-3.3	-3.9	-2.9	3.4	-2.9	-2.6	-2.9	-1.0	-2.2	-2.6	-2.6	-1.6	-3.0	-2.6	-2.0	-2.2	-0.9
Asthma	3.5	6.9	13.7	-3.1	-2.1	-1.6	-1.7	-2.6	1.2	-3.4	-2.4	-3.1	-3.7	-3.0	-3.0	-3.2	-0.3	-2.0	-2.5	-3.5	-2.3	-2.7
Worry too long after embarrassment	3.3	5.6	11.5	-2.4	-1.5	-3.2	-2.1	-1.9	2.5	-2.6	-3.1	-1.9	-0.2	-0.5	-3.1	-3.4	-1.7	-3.2	-2.6	-0.9	-2.1	-2.7
Ever unenthusiastic/disinterested for a whole week	3.2	3.9	7.5	-2.3	-1.2	-2.1	-2.7	-1.5	2.7	-1.6	-2.3	-1.8	-1.1	-2.2	-2.4	-2.3	-0.6	-2.5	-2.3	-0.4	-2.4	-0.1
Frequency of tiredness / lethargy in last 2 weeks	3.2	5.2	11.6	2.7	0.5	1.5	2.3	1.9	-2.1	3.4	2.2	2.1	3.2	2.4	2.2	2.1	-0.4	2.4	2.6	3.4	2.2	1.0
Neuroticism (Nagel 2018)	3.1	7.3	13.7	-2.7	-1.0	-2.7	-2.8	-2.8	3.0	-2.7	-3.5	-2.8	-0.2	-0.8	-3.3	-3.7	-3.2	-3.6	-2.7	-1.1	-1.7	-3.3
Impedance of arm (left)	3.1	14.2	30.1	-2.9	1.3	-3.5	-5.5	-3.5	5.2	-3.8	-3.8	-3.5	-4.4	-5.4	-3.5	-2.1	2.6	-3.1	-4.0	-4.5	-3.7	2.2
Fractured/broken bones in last 5 years	3.1	4.0	10.2	1.7	-0.3	1.7	1.2	1.8	-1.9	2.3	1.9	0.5	2.6	2.5	3.2	2.2	0.3	2.0	2.8	1.9	2.7	1.5
Body Mass Index (BMI) (2010)	3.0	4.2	10.0	2.1	-1.4	1.1	3.1	2.4	-3.2	2.2	2.3	0.8	1.6	1.7	2.3	1.3	-0.2	2.0	2.6	2.6	1.9	-1.3
Asthma (self-reported)	3.0	6.0	11.9	-2.9	-2.2	-1.3	-1.7	-2.6	1.0	-3.2	-2.2	-3.2	-3.5	-2.6	-2.7	-3.0	-0.1	-1.8	-2.3	-3.2	-2.1	-2.3
Osteoarthritis (self-reported)	3.0	3.9	13.4	2.4	0.2	0.9	3.7	1.7	-2.7	1.8	2.2	1.3	1.0	1.8	2.0	1.8	-0.6	2.6	2.3	1.4	2.5	-1.2
Diabetes (father)	2.9	3.6	10.6	-2.3	0.3	-0.7	-3.3	-2.7	2.5	-2.0	-1.5	-1.6	-2.3	-2.4	-1.8	-1.8	-0.2	-1.9	-1.8	-2.1	-1.5	-0.0
Townsend deprivation index at recruitment	2.9	4.1	11.9	1.8	-1.2	2.3	2.9	1.1	-3.5	1.7	3.1	0.9	1.0	0.9	2.4	2.0	-0.5	2.5	2.5	1.8	1.7	-1.1
Comparative body size at age 10	2.9	8.0	21.4	1.5	-2.8	2.6	4.6	2.4	-4.6	1.8	3.3	0.3	3.0	2.7	2.3	1.5	-1.9	2.9	2.6	2.7	2.9	-3.8
Diabetes (mother)	2.8	3.5	5.9	1.9	1.1	2.4	1.8	2.2	-1.5	2.2	1.7	2.1	2.0	2.4	2.1	2.3	0.7	1.7	1.8	1.5	1.9	1.3
Maternal smoking around birth	2.8	4.0	10.1	1.7	-0.5	3.2	2.4	2.2	-2.6	1.8	1.9	2.1	1.9	2.9	2.0	1.8	0.5	2.1	2.1	1.4	2.0	-0.2
Diverticular disease/diverticulitis (self-reported)	2.8	3.3	9.5	2.1	2.9	0.4	1.2	0.1	-1.1	2.0	0.6	2.9	1.4	1.7	1.3	2.2	3.1	2.2	1.3	1.5	1.9	1.3
Pain all over the body in last month	2.8	3.0	6.4	2.0	0.9	2.2	1.8	1.3	-1.6	2.0	1.3	1.8	2.1	2.5	2.1	1.9	0.2	1.8	1.9	1.4	1.8	0.1
Medication: Aspirin	2.8	3.7	8.9	2.0	-0.6	1.8	2.5	2.1	-3.0	1.4	2.7	1.5	1.2	2.3	2.4	2.6	-0.4	2.2	2.1	0.6	1.5	-0.2
Ever had prostate specific antigen (PSA) test	2.8	3.2	9.2	1.6	0.3	1.5	2.3	0.6	-2.5	1.8	1.9	1.4	1.5	1.3	1.5	1.7	2.4	3.0	1.7	1.5	2.3	-0.1
Lupus	2.7	4.0	21.1	-1.3	-4.6	0.9	0.2	-0.6	-0.7	-1.3	-1.3	-3.5	-0.6	-0.3	-1.2	-3.1	-1.9	-1.6	-0.3	0.5	-0.4	-4.3
Number of children fathered	2.7	3.0	7.7	2.0	1.8	1.6	1.5	1.8	-0.7	2.8	0.7	1.7	2.4	1.9	1.6	1.6	-0.5	1.2	1.6	2.1	1.8	1.9
Number of treatments/medications taken	2.6	4.6	17.3	2.5	-0.8	2.4	1.9	1.4	-2.2	2.1	1.6	0.7	2.6	4.2	2.4	1.4	0.2	2.0	2.6	1.9	3.2	-0.6
Medication: Co-codamol	2.6	3.1	7.7	1.2	-1.5	1.9	1.9	0.9	-2.8	2.0	2.4	1.3	1.6	0.8	1.9	1.4	-0.7	2.3	2.3	2.1	1.5	-0.6
Cardiovascular Disease	2.5	8.2	25.9	3.0	-2.0	2.8	2.8	1.7	-3.5	2.3	2.8	0.6	3.5	5.1	3.7	2.0	-1.7	2.5	3.6	2.3	3.7	-1.0
Supplements: Zinc	2.5	2.7	10.3	1.7	2.3	-0.4	0.2	-0.3	-0.9	1.3	1.7	1.3	0.9	0.3	1.5	2.7	3.2	2.4	1.2	0.5	0.8	2.8
Taking other prescription medications	2.5	3.8	11.0	2.6	-1.5	1.3	1.2	2.0	-2.2	2.2	1.8	0.1	2.0	3.3	2.6	1.4	-0.4	1.7	2.6	2.2	2.4	-0.4
Had other major operations	2.5	3.0	5.0	2.2	-0.1	1.7	1.7	1.5	-2.0	2.0	1.9	1.4	1.1	1.7	2.2	1.7	1.1	2.1	2.1	2.0	1.6	1.3
Hypertension (Self-reported)	2.5	6.9	23.6	3.0	0.3	3.6	2.8	2.1	-2.2	2.5	1.8	2.0	3.6	4.9	2.9	1.6	-0.2	2.1	3.0	1.8	3.8	-0.2
Mineral and other dietary supplements	2.5	3.4	13.4	-2.1	-3.1	-0.7	-0.2	0.3	0.4	-1.6	-1.1	-2.4	-0.9	-0.5	-1.0	-2.5	-3.7	-2.4	-1.1	-0.4	-1.2	-2.9
Medication: Levothyroxine sodium	2.4	4.1	12.6	0.7	-3.5	0.1	1.5	2.1	-2.2	0.4	1.7	-2.9	1.9	2.9	2.1	-0.0	-3.3	-0.3	1.8	1.5	1.1	-2.9
Tinnitus: Yes, now most or all of the time	2.4	2.8	8.1	1.6	1.5	1.1	0.9	0.7	-0.6	2.4	1.1	2.8	1.4	1.6	1.5	2.3	1.5	2.1	1.2	1.6	1.3	2.3
Bipolar Disorder or Schizophrenia	2.3	5.7	10.4	3.2	1.8	2.1	2.2	2.8	-1.9	3.1	2.6	2.1	0.9	1.6	3.0	3.1	1.7	2.5	2.7	2.3	2.0	2.6
Schizophrenia (2018)	2.3	4.8	9.7	3.1	2.0	1.5	1.2	2.5	-1.5	2.9	2.3	2.3	0.8	1.5	2.7	3.0	1.6	2.1	2.3	2.0	1.4	3.0
Other serious medical condition/disability diagnosed by doctor	2.3	3.0	6.5	2.1	-0.0	1.0	1.6	1.0	-2.1	1.9	2.4	0.3	1.6	1.3	2.5	2.1	0.6	2.2	2.6	1.5	2.2	0.3
Angina	2.3	3.0	5.2	2.1	-0.2	2.3	1.8	2.1	-1.8	1.7	1.8	1.3	1.6	2.2	2.2	1.7	-1.7	1.3	2.2	1.4	1.6	-0.1
Severe depression (siblings)	2.3	2.6	4.1	-1.9	-1.9	-1.4	-2.0	-1.4	1.2	-1.8	-0.9	-1.2	-1.5	-1.1	-1.7	-1.5	-2.0	-1.6	-1.9	-1.6	-1.8	-1.4
Age at first live birth	2.3	4.0	10.1	-1.5	0.5	-3.0	-3.2	-2.8	2.6	-1.8	-2.0	-1.6	-1.6	-1.8	-2.1	-1.6	-1.0	-2.2	-2.4	-1.1	-2.4	0.1
Angina (self-reported)	2.3	3.0	4.9	2.2	-0.2	2.1	2.0	2.1	-1.9	1.6	1.9	1.1	1.6	2.2	2.2	1.7	-1.6	1.4	2.2	1.2	1.6	-0.0
Vascular/heart problems diagnosed by doctor	2.3	6.2	22.2	-3.0	0.3	-3.4	-2.3	-2.0	2.4	-2.2	-1.9	-1.6	-3.2	-4.7	-3.0	-1.7	0.5	-2.0	-2.9	-1.6	-3.3	0.2
Rheumatoid Arthritis	2.2	3.0	6.7	2.2	0.3	1.4	1.2	2.1	-1.4	2.6	2.2	0.6	1.1	0.9	2.3	2.0	0.6	1.7	2.1	2.1	1.4	2.2
Fed-up feelings	2.2	4.1	14.5	-1.9	-3.1	-0.7	-1.0	-1.9	0.6	-1.7	-1.1	-3.3	0.1	0.0	-1.5	-2.6	-3.8	-2.3	-1.2	-0.2	-1.4	-3.3
Heart disease (mother)	2.2	2.7	5.8	1.9	1.2	1.6	1.8	1.4	-1.5	1.9	1.0	1.7	1.8	2.4	1.8	1.8	1.6	1.7	1.5	1.2	1.4	1.4
Blood White Count	2.1	15.2	38.8	-3.5	-0.5	-5.1	-5.9	-2.2	6.2	-3.4	-5.1	-2.2	-2.4	-0.1	-4.3	-4.0	-1.0	-5.8	-5.2	-2.6	-4.6	-0.2
Medication for hormone replacement therapy	2.1	2.3	4.4	1.9	1.2	1.1	1.1	1.7	-1.0	2.1	1.4	1.8	1.2	0.9	1.7	1.9	1.1	1.8	1.6	1.4	1.2	2.0
Bilateral oophorectomy (both ovaries removed)	2.1	2.4	6.8	2.0	1.9	1.2	0.5	1.6	0.2	1.8	0.5	2.6	1.6	2.5	0.6	1.6	1.4	1.2	0.7	1.4	0.6	2.3
High blood pressure	2.1	5.8	21.1	2.9	0.2	3.2	2.5	2.2	-2.1	2.2	1.7	1.7	3.4	4.6	2.8	1.5	-0.3	1.8	2.6	1.6	3.3	-0.1
Headache pain in last month	2.1	3.6	5.7	2.3	-0.8	2.2	2.2	1.9	-2.3	1.8	2.3	0.5	1.9	2.4	1.8	1.1	-2.2	1.1	2.0	2.3	2.0	-1.1
Chronic bronchitis/emphysema (mother)	2.1	2.5	7.8	1.9	0.8	0.8	0.8	0.7	-1.3	1.7	1.1	1.8	1.6	2.8	1.7	1.7	1.7	2.0	1.7	1.0	2.2	0.6
Medication: Paracetamol	2.1	3.2	7.2	2.4	0.0	1.3	2.2	2.1	-1.8	2.0	1.6	0.4	1.5	2.7	1.8	1.2	-0.6	1.4	2.2	2.5	2.4	-0.8
Commuting to job workplace: Cycle	2.1	2.5	6.5	-0.6	2.5	-1.9	-2.1	-2.0	2.4	-0.7	-2.0	0.0	-1.4	-1.5	-1.8	-1.2	-0.3	-1.6	-2.0	-0.9	-1.2	0.4
Had major operations	2.0	2.4	4.3	1.7	0.6	1.9	0.9	1.4	-1.0	2.0	1.1	1.8	1.8	1.4	1.8	1.6	1.4	1.5	1.5	2.1	1.5	1.5
Number of full sisters	1.9	2.3	5.3	2.0	-0.9	1.6	1.2	2.3	-1.8	1.8	1.7	-0.0	1.0	1.9	1.9	1.2	-1.3	0.9	2.0	1.6	1.2	-0.0
Medication: Bendroflumethiazide	1.9	2.9	5.5	2.0	-0.3	1.7	1.6	1.4	-1.7	2.0	1.9	1.1	2.1	2.3	2.0	1.5	-1.1	1.5	2.2	1.6	2.0	-0.1
Neuroticism (2016)	1.8	2.6	8.7	-1.9	-0.9	-0.9	-1.7	-3.0	1.5	-1.9	-1.7	-1.0	-0.6	-1.0	-2.0	-2.1	-1.4	-1.6	-1.6	-1.2	-1.0	-1.6
Hearing difficulty/problems with background noise	1.8	3.0	6.6	1.5	0.3	0.5	1.2	0.4	-1.4	2.4	2.0	0.8	2.1	-0.1	2.5	1.9	-0.9	2.2	2.6	2.1	2.3	1.7
Birth weight	1.8	3.9	13.3	-3.2	1.6	-0.9	-3.0	-2.1	3.6	-1.4	-2.7	0.0	-1.4	-2.1	-2.1	-1.8	-0.2	-1.9	-2.1	-1.7	-0.3	0.3
Loneliness, isolation	1.8	2.5	11.8	0.3	-2.8	1.7	2.2	0.4	-2.2	0.2	0.5	-0.8	1.4	1.3	0.3	-0.8	-3.0	-0.2	0.8	1.2	0.1	-3.4
Crohns Disease (2012)	1.7	2.7	7.3	-0.9	0.6	-0.8	-1.3	0.1	2.3	-1.8	-2.5	0.2	-0.5	0.1	-2.7	-2.3	-1.1	-2.3	-2.6	-1.2	-1.6	-1.8
Hair/balding pattern: Pattern 3	1.7	2.5	4.8	-1.6	0.1	-1.0	-0.9	-2.1	1.9	-2.0	-2.2	-0.6	-1.8	-1.2	-1.9	-1.8	1.1	-1.2	-2.2	-2.0	-1.4	-1.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.7	2.0	3.9	1.6	-0.7	1.1	0.9	0.1	-1.7	1.9	1.7	0.1	1.7	1.9	1.8	1.1	-0.5	1.6	2.0	1.7	1.5	-0.0
Guilty feelings	1.7	2.6	6.4	-2.1	-0.4	-1.7	-1.5	-1.8	2.0	-1.8	-2.5	-1.4	-0.2	-0.5	-2.2	-2.1	0.3	-1.7	-1.8	-1.2	-1.0	-1.5
Ever depressed for a whole week	1.7	2.1	5.0	-1.1	-0.7	-1.4	-1.7	-0.5	1.8	-0.9	-1.4	-1.4	-1.5	-1.9	-1.8	-1.6	-1.4	-2.1	-1.6	-0.0	-2.2	-0.3
Schizophrenia (2014)	1.6	3.5	6.7	2.5	1.0	1.6	1.3	1.6	-1.8	2.5	2.5	1.5	0.4	1.2	2.4	2.6	1.6	1.9	2.1	2.1	0.6	2.4
Serious illness, injury or assault to yourself	1.6	1.9	7.6	1.8	0.6	1.6	-0.0	0.8	-0.4	2.0	0.9	0.8	1.9	2.8	1.3	1.3	0.9	1.0	1.3	1.8	1.1	1.4
Hair/balding pattern: Pattern 4	1.6	3.8	10.5	-1.7	-0.7	-2.3	-2.6	-0.3	2.5	-1.9	-2.3	-1.2	-1.4	0.1	-2.3	-1.8	-1.1	-2.8	-2.7	-1.5	-3.2	-0.4
Medication: Amlodipine	1.6	2.3	10.2	1.5	0.6	2.0	0.5	1.9	-0.5	1.4	0.5	0.4	3.0	3.2	1.5	1.0	0.1	0.7	1.3	1.3	2.0	0.5
Ulcerative Colitis (UC)	1.5	2.8	8.5	-1.3	0.7	-1.8	-2.5	-0.1	2.9	-1.3	-2.8	-0.7	-0.7	0.1	-2.3	-2.1	-0.1	-2.4	-2.2	-0.8	-1.4	0.0
Number of incorrect matches in round	1.5	2.6	5.7	1.9	1.5	0.6	0.2	1.2	-0.8	1.8	2.0	1.2	1.9	0.8	2.0	2.2	0.9	1.7	1.8	1.7	1.6	2.4
Eye problems/disorders: None of the above	1.5	1.7	6.0	-1.4	-1.4	-0.4	-1.2	-0.8	1.0	-1.0	-1.2	-2.5	-0.4	-1.5	-1.3	-2.0	-1.0	-1.9	-1.1	-0.0	-1.8	-0.6
Number of self-reported non-cancer illnesses	1.5	2.6	7.0	1.6	-1.8	1.4	1.8	1.1	-2.7	1.0	1.9	-0.4	1.0	2.1	2.1	1.1	-0.7	1.6	2.0	0.8	1.9	-1.6
Eye problems/disorders: Glaucoma	1.5	1.7	7.4	1.7	1.2	0.6	1.0	2.0	0.0	1.4	0.1	0.8	1.5	2.7	1.4	1.1	-0.3	0.9	1.1	0.8	2.1	0.4
Ulcerative Colitis	1.4	2.1	7.7	-0.8	1.5	-1.5	-1.8	0.1	2.8	-0.9	-2.6	0.0	-0.3	0.7	-2.0	-1.5	-0.4	-1.9	-1.9	-0.9	-0.6	0.3
Ever used hormone-replacement therapy (HRT)	1.4	1.7	6.3	1.5	1.5	1.1	0.9	0.2	-1.1	1.7	0.6	2.5	0.9	1.0	1.1	1.7	1.4	1.8	1.1	0.9	0.9	1.2
Average weekly fortified wine intake	1.4	1.7	3.6	-1.7	0.8	-1.2	-0.9	-0.8	1.2	-1.5	-1.4	-0.8	-1.0	-1.9	-1.7	-0.7	1.9	-0.5	-1.6	-1.5	-1.4	0.9
Falls in the last year	1.4	1.9	6.0	0.8	-1.2	0.9	1.0	0.1	-2.1	1.2	2.4	-0.3	-0.0	-0.3	2.0	1.9	0.2	2.1	2.0	1.0	1.4	1.0
Pulse rate	1.4	2.4	5.1	-1.4	-0.0	-0.4	-1.9	-2.2	2.2	-1.4	-2.2	-0.3	-1.1	-1.1	-2.2	-2.0	-0.4	-1.6	-2.0	-1.7	-1.0	0.1
Hypothyroidism/myxoedema (self-reported)	1.4	2.7	8.5	0.5	-2.9	0.4	1.1	1.7	-1.9	0.6	1.8	-2.4	1.8	2.1	2.0	0.2	-2.1	0.0	1.7	1.4	1.1	-1.5
Medication: Ibuprofen	1.4	1.6	4.4	2.0	-0.3	1.1	1.7	1.0	-2.0	1.3	1.6	-0.1	0.5	2.1	0.8	0.7	-0.4	1.0	1.4	2.0	0.7	-0.8
Depression (Nagel 2018)	1.3	1.9	6.2	-1.4	0.4	-0.8	-1.7	-0.9	2.4	-0.7	-2.5	-0.8	-0.5	-1.1	-1.9	-2.1	-0.4	-1.8	-1.5	-0.1	-0.7	-0.7
Blood Red Count	1.3	12.3	22.8	-4.8	-2.8	-3.2	-3.0	-2.7	2.5	-4.3	-3.4	-1.4	-4.1	-0.7	-4.6	-4.8	-2.1	-3.9	-4.3	-3.6	-3.4	-3.8
Hypothyroidism (self reported)	1.3	3.0	12.0	0.1	-3.5	0.1	0.5	1.4	-1.5	0.3	1.8	-2.9	2.0	2.1	1.8	-0.2	-2.8	-0.4	1.6	1.5	1.2	-1.8
Respiratory disease	1.3	2.8	9.9	-1.8	-1.1	-0.2	-1.2	-2.1	0.8	-1.8	-1.7	-1.5	-3.2	-2.5	-2.1	-2.0	0.4	-1.0	-1.4	-1.8	-1.7	-0.6
Neuroticism	1.3	3.1	7.1	-1.8	-1.3	-0.8	-1.8	-2.0	1.6	-1.5	-2.4	-1.7	1.2	0.3	-1.9	-2.7	-2.5	-2.2	-1.4	-0.2	-0.8	-2.6
Lung cancer (father)	1.3	1.6	3.3	1.7	-0.1	0.3	1.3	1.8	-1.5	1.2	1.6	1.4	1.1	1.3	1.4	1.8	-0.1	1.1	1.1	1.6	0.3	0.7
Mouth/teeth dental problems: Loose teeth	1.3	1.5	7.0	0.2	-2.2	0.9	2.4	1.3	-2.6	0.5	1.6	-0.3	-0.3	-0.4	0.5	0.5	-0.5	1.5	0.8	0.4	-0.2	-1.5
Neck or shoulder pain in last month	1.3	1.8	7.6	1.1	0.4	0.8	2.8	1.5	-1.8	0.9	1.2	0.9	1.7	1.0	0.9	0.5	-1.3	1.0	1.1	1.2	1.8	-1.6
Average weekly red wine intake	1.3	1.9	4.8	1.7	0.8	0.2	1.2	1.5	-1.1	1.8	1.4	1.1	0.6	0.5	1.4	1.5	2.0	2.2	1.6	0.9	1.4	1.6
Breast cancer (self-reported)	1.3	1.5	4.1	-0.8	1.3	-1.0	-1.5	-1.1	2.0	-0.7	-1.8	0.5	-1.4	-1.1	-1.5	-0.4	2.0	-0.6	-1.4	-1.2	-0.7	1.0
Alcohol drinker status: Previous	1.3	1.4	3.9	1.5	-0.3	1.3	0.6	1.5	-1.1	1.2	1.0	-0.1	1.2	2.0	1.6	0.8	1.2	0.9	1.6	1.4	1.4	0.4
Systolic Blood Pressure	1.2	5.9	16.3	-1.7	0.1	-1.3	-3.5	-1.9	4.0	-2.8	-3.8	-2.7	-1.2	-0.5	-2.1	-3.4	-1.5	-3.4	-2.4	-2.8	-0.7	0.1
Ever taken oral contraceptive pill	1.2	1.3	4.2	-0.6	0.6	-1.6	-1.7	-0.4	2.0	-0.9	-1.5	-0.0	-1.1	-0.1	-1.3	-0.9	-1.1	-1.7	-1.5	-0.8	-1.3	-0.1
Hearing aid user	1.2	1.3	4.4	-0.8	-1.7	-0.7	-1.5	-1.8	0.1	-1.0	-0.7	-1.0	-2.1	-1.4	-0.9	-1.0	0.4	-0.8	-0.7	-0.7	-1.9	0.0
Medication: Atenolol	1.1	1.4	5.8	0.7	-1.0	1.8	0.9	1.5	-1.1	0.6	0.4	-0.5	0.7	2.4	0.8	-0.3	-1.7	-0.2	1.2	1.1	1.3	-1.7
Hayfever/allergic rhinitis (self-reported)	1.1	1.4	3.4	-1.6	-1.1	-1.0	-0.2	0.7	1.2	-1.4	-1.6	-1.8	-0.8	-0.5	-1.0	-1.3	-0.1	-1.7	-1.4	-1.0	-1.5	-0.6
Time employed in main current job	1.1	1.3	4.5	-0.9	-1.2	-1.3	-1.1	-2.0	0.6	-0.9	-0.0	-2.1	-0.5	-2.1	-0.4	-1.1	-1.6	-0.6	-0.2	-0.6	-0.1	-0.5
Alcohol intake versus 10 years previously	1.1	1.6	5.1	-1.2	-0.7	-2.2	-1.9	0.2	1.8	-1.0	-1.3	-1.4	0.3	0.6	-0.7	-1.5	-1.3	-2.3	-0.9	-0.5	-0.7	-0.5
Depression (self-reported)	1.1	1.3	3.2	-1.2	-1.3	-0.6	-1.0	-0.9	1.1	-1.2	-1.3	-1.7	-0.3	-0.7	-1.1	-1.6	-1.3	-1.8	-1.1	-0.5	-1.4	-0.5
Wheeze or whistling in the chest in last year	1.1	2.0	5.4	-1.6	-0.5	-0.8	-0.8	-1.2	1.0	-1.6	-1.4	-1.3	-2.3	-2.1	-1.7	-1.6	-0.1	-1.0	-1.2	-2.2	-1.2	-0.2
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.1	1.3	4.4	1.4	-0.4	1.0	0.9	1.1	-1.5	1.2	1.1	0.6	1.7	1.0	1.1	0.6	-0.2	0.8	1.4	2.1	0.9	0.1
Handedness (chirality/laterality): Left-handed	1.1	1.3	4.9	-0.7	0.3	-0.7	-1.1	-0.1	1.9	-1.0	-2.2	-0.4	-1.7	0.5	-1.3	-1.5	0.4	-1.3	-1.4	-1.1	-0.1	-0.6
Age at First Birth	1.0	1.4	3.7	-1.3	0.1	-1.1	-1.4	-0.6	1.6	-1.4	-1.6	-0.8	-0.8	-1.4	-0.9	-1.0	-1.2	-1.2	-1.5	-1.9	-0.3	-0.7
Type 2 Diabetes (T2D) (2012)	1.0	1.2	5.2	0.3	1.8	0.4	-1.0	-1.0	1.5	0.3	-1.4	1.0	-0.2	2.3	0.5	0.2	0.9	-0.1	0.3	-0.7	1.6	1.5
Type 2 Diabetes (T2D) (2018)	1.0	1.9	8.6	1.4	1.7	0.4	0.9	2.3	0.3	1.5	0.3	1.8	1.4	2.9	1.0	1.3	0.2	0.6	1.0	0.6	1.9	0.2
Illnesses of mother	1.0	1.2	4.0	-0.9	-0.1	-0.4	-2.0	-1.0	1.8	-0.4	-1.2	-1.1	-0.9	-1.9	-0.8	-1.2	-0.5	-1.3	-0.9	0.0	-1.0	0.6
Pulse wave Arterial Stiffness index	1.0	1.2	3.3	0.7	1.2	1.2	0.6	-0.1	-0.5	1.6	1.2	1.8	0.6	0.7	1.0	1.2	1.1	1.3	1.1	0.5	1.1	1.4
Gout (self-reported)	1.0	1.4	3.8	-0.4	-0.6	-0.6	-1.1	-0.4	0.9	-1.7	-1.1	-1.7	-1.5	0.5	-0.9	-1.4	-0.8	-1.9	-1.0	-1.6	-1.2	-1.4
Medication: Ventolin 100micrograms inhaler	1.0	1.3	2.8	-0.7	-0.3	-0.8	-1.3	-1.1	0.4	-1.7	-1.1	-0.4	-1.3	-1.0	-1.5	-1.0	1.5	-0.6	-1.4	-1.6	-1.6	-0.6
Age at last live birth	1.0	1.5	5.5	-0.5	0.4	-2.4	-1.6	-1.4	1.5	-1.1	-1.1	-1.3	-0.9	-0.7	-1.3	-0.8	-0.9	-1.6	-1.5	-0.5	-1.5	-0.3
Commuting to job workplace: Walk	1.0	1.0	4.8	-1.1	-0.6	-0.8	-0.5	-0.6	0.6	-0.9	-0.5	-0.4	-2.2	-1.9	-1.3	-0.7	0.3	-0.5	-1.0	-0.9	-1.5	0.1
Medication: Lisinopril	1.0	1.3	4.4	1.2	-0.0	1.9	0.8	0.8	-0.4	1.3	-0.2	1.2	2.1	2.0	0.8	0.1	0.2	0.6	1.1	1.3	1.7	0.3
Risk taking	1.0	1.4	4.5	0.8	-0.6	-0.2	2.0	0.3	-2.1	0.9	1.3	0.6	1.5	1.8	1.2	1.0	-0.1	1.6	1.1	0.9	1.0	-1.0
Cholesterol lowering medication	1.0	1.5	5.3	0.5	-0.5	0.8	2.3	0.5	-1.9	0.6	1.0	1.4	1.0	1.4	1.0	0.9	0.4	1.9	1.2	-0.3	1.8	-0.7
Bipolar Disorder (2018)	0.9	1.4	4.2	1.3	0.5	1.4	2.1	1.3	-1.1	1.4	1.4	0.6	0.5	0.6	1.4	1.2	0.6	1.3	1.4	1.2	1.4	0.5
Depressed Affect (Nagel 2018)	0.9	1.9	9.7	-0.8	-2.0	0.4	0.1	-0.6	-0.2	-0.4	-0.9	-1.7	1.0	1.2	-0.6	-1.7	-3.1	-1.3	-0.1	0.8	-0.1	-3.1
Alzheimer’s Disease (including proxy)	0.9	1.3	4.8	-1.0	1.4	-2.2	-1.1	-0.8	1.8	-0.8	-1.6	0.3	0.2	0.5	-1.4	-0.6	1.7	-0.5	-1.6	-0.9	-0.4	0.1
Irritable Bowel Disease (IBD)	0.9	2.1	6.5	-0.6	0.7	-1.4	-1.6	0.4	2.3	-1.1	-2.5	-0.3	-0.5	0.9	-2.2	-1.9	-0.5	-2.2	-2.0	-0.5	-1.2	-0.7
Systolic blood pressure, automated reading	0.9	2.7	9.2	-1.4	-0.4	-0.2	-2.1	-1.1	2.8	-1.7	-3.0	-2.0	0.1	0.1	-1.2	-2.8	-0.8	-2.4	-1.4	-1.7	0.4	-0.2
Tinnitus: Yes, but not now, but have in the past	0.9	0.9	2.3	1.4	0.6	0.7	0.5	1.2	-0.8	1.1	1.2	0.6	0.2	0.5	1.5	1.3	0.1	0.6	1.3	0.9	0.6	1.5
Financial difficulties in last 2 years	0.9	1.2	3.9	1.1	-1.6	0.1	1.4	0.8	-2.0	0.3	1.4	-0.9	0.9	1.7	1.3	0.7	-1.1	0.5	1.1	0.4	0.8	-0.8
Neuroticism score	0.9	1.9	6.0	-1.5	-1.2	-0.7	-0.9	-1.4	0.9	-1.1	-1.5	-1.6	1.2	0.3	-1.3	-2.0	-2.5	-1.5	-0.9	0.0	-0.4	-2.4
Medication: Ibuprofen (e.g. Nurofen)	0.9	1.1	3.3	1.4	-0.8	0.9	1.5	0.8	-1.8	0.7	1.7	-0.8	-0.0	1.3	0.6	0.4	-0.9	0.6	1.1	1.3	0.2	-1.1
Medication: Lansoprazole	0.9	1.1	5.1	1.5	-0.5	0.9	0.7	1.0	-0.8	1.1	0.8	-0.0	1.2	2.3	1.5	0.7	-0.5	0.6	1.1	1.3	0.8	0.3
Medication: Paracetamol	0.9	1.5	3.5	1.6	-0.2	1.2	1.6	1.3	-1.4	1.2	1.2	0.0	0.7	1.9	1.1	0.7	-1.0	0.9	1.4	1.4	1.5	-1.2
Qualifications: NVQ or HND or HNC or equivalent	0.9	1.1	4.3	0.6	-1.8	1.2	2.1	0.8	-2.0	0.4	1.0	-0.4	0.2	0.3	0.9	0.2	-0.9	1.0	1.1	0.4	0.3	-1.0
Illnesses of siblings: Diabetes	0.9	1.1	3.5	1.3	0.2	0.4	1.3	1.2	-0.8	1.3	0.9	1.3	0.7	1.9	1.2	0.8	-0.6	1.0	1.3	0.6	1.4	-0.1
Mood swings	0.9	1.7	9.9	0.6	-1.1	1.2	0.9	0.5	-1.2	0.4	0.3	-0.2	2.0	2.1	0.5	-0.4	-3.1	-0.1	0.8	0.8	0.8	-2.4
Friendships satisfaction	0.9	1.2	2.8	-1.1	-1.0	0.2	-0.6	-0.8	0.7	-1.3	-1.0	-0.6	-1.5	-1.1	-1.4	-1.6	-0.7	-0.9	-1.2	-0.9	-0.7	-1.7
Major Depression (MDD)	0.8	1.0	3.6	-0.8	-0.7	-0.4	-0.7	-0.5	0.6	-1.1	-0.8	-0.8	-1.2	-1.9	-1.1	-1.4	0.0	-1.2	-1.0	-1.0	-1.0	-0.9
Breast Cancer	0.8	1.8	3.3	1.4	0.7	1.8	0.8	1.7	-0.8	1.8	1.8	1.4	1.4	1.1	1.6	1.5	-1.0	1.2	1.2	1.7	0.6	0.9
Fasting Glucose	0.8	0.9	5.5	0.5	1.3	1.7	1.0	0.5	-0.6	0.7	0.5	2.4	0.7	0.9	0.0	1.1	0.7	0.8	0.0	0.4	-0.1	1.2
Supplements: Glucosamine	0.8	1.1	5.4	0.8	1.7	-0.6	0.2	-0.4	-0.2	0.9	0.7	1.0	0.2	-0.3	0.1	1.2	2.3	1.4	0.4	0.2	0.3	2.0
Qualifications: A levels/AS levels or equivalent	0.8	1.8	5.0	-0.5	1.9	-0.7	-1.5	-0.1	2.0	-0.9	-1.7	0.9	-1.7	-1.4	-1.9	-0.6	0.1	-1.6	-1.7	-0.3	-2.2	0.6
Serious illness, injury or assault of a close relative in last 2 years	0.8	0.9	4.4	1.3	1.6	0.9	-0.7	-0.6	0.1	0.8	-0.2	1.3	0.3	2.1	0.8	0.4	0.9	0.4	0.4	-0.1	1.4	0.5
Birth weight of first child	0.8	1.5	6.2	-1.9	1.8	-0.1	-2.0	-0.7	2.5	-0.6	-0.8	1.0	-1.0	-0.7	-0.9	-0.3	0.3	-0.9	-1.4	-1.5	-0.1	1.3
High blood pressure (siblings)	0.8	1.2	6.4	1.5	1.1	0.8	0.4	1.1	-0.1	1.3	0.0	0.9	1.3	2.5	1.1	0.6	-0.4	-0.0	1.1	0.9	1.4	0.8
Number of full brothers	0.8	1.1	6.2	0.3	-1.3	0.5	0.3	-0.5	-1.5	-0.7	0.8	-1.1	-0.4	1.0	0.6	-0.1	-2.2	-0.7	0.5	-0.3	-0.2	-2.5
Migraine (self-reported)	0.8	1.0	4.0	0.3	-2.0	0.6	0.8	-0.7	-2.0	-0.6	1.7	-1.0	-0.4	-0.0	0.8	0.8	0.7	0.7	0.7	-0.6	-0.1	-1.5
Ever had bowel cancer screening	0.8	1.0	1.8	0.8	-0.3	0.4	1.2	0.9	-1.3	1.3	1.3	0.5	1.2	0.6	1.0	1.0	0.1	1.3	1.2	1.4	1.1	0.2
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.8	1.7	9.9	0.3	3.1	-1.6	-1.1	0.3	1.1	0.1	-0.0	2.2	-1.4	-0.5	-0.3	1.3	1.4	-0.0	-0.8	-0.6	-0.8	2.3
Alzheimer’s Disease (in mother)	0.7	0.8	3.1	-0.4	1.2	-1.8	-1.1	-0.2	1.4	-0.6	-0.9	0.1	0.3	0.8	-0.9	-0.3	0.6	-0.9	-1.3	-0.6	-0.6	0.6
Ovarian Cancer	0.7	0.9	3.5	-0.7	0.4	-1.9	-1.2	-0.2	1.3	-0.8	-1.4	-1.1	-0.6	0.1	-1.4	-0.9	0.1	-0.8	-1.3	-0.5	-0.8	-0.4
Blood Eosinophil Count	0.7	5.5	16.0	-0.8	-0.8	-1.9	-3.9	-1.4	4.0	-1.7	-3.9	-3.5	-1.1	1.8	-1.7	-2.0	-0.1	-3.9	-1.9	-1.2	-2.0	0.2
Vitamin and mineral supplements	0.7	1.0	7.3	0.2	-1.6	0.2	1.6	2.7	-1.0	0.8	0.6	-0.1	-0.4	-0.2	0.9	0.1	-1.3	0.3	0.6	0.9	-0.2	0.2
Heel bone mineral density (BMD) T-score, automated (left)	0.7	1.6	5.4	-0.5	-0.6	-1.1	-1.6	-0.5	1.1	-0.7	-1.2	-0.5	0.2	0.8	-1.2	-1.0	-2.3	-2.2	-1.4	0.1	-2.3	-1.0
Qualifications: CSEs or equivalent	0.7	1.0	5.2	-1.1	-2.3	-0.3	-0.4	-1.5	-0.6	-1.0	0.4	-1.5	-0.9	-0.9	0.2	-0.5	-1.5	-0.6	0.0	-0.5	-0.6	-0.9
High blood pressure (mother)	0.7	0.9	2.7	0.2	-1.1	0.2	1.5	0.5	-1.5	0.2	1.4	-0.5	0.6	0.5	1.0	0.3	-1.7	0.3	1.1	0.5	1.0	-1.5
Hair/balding pattern: Pattern 2	0.7	0.9	3.5	0.8	1.4	0.6	0.9	0.2	-0.7	0.7	0.8	1.1	1.8	0.8	0.8	0.8	0.3	0.9	1.1	0.7	1.9	0.0
Father’s age at death	0.7	0.9	2.7	-0.9	-0.4	-1.5	-0.9	-0.4	0.6	-0.9	-0.5	-1.7	-1.0	-1.2	-1.0	-0.9	0.7	-0.7	-0.8	-0.6	-1.2	-0.7
Prospective memory result	0.7	0.9	3.7	-0.9	-0.3	-0.1	-1.0	-1.3	1.0	-0.9	-0.8	-1.3	-0.1	-1.4	-0.5	-0.8	-1.9	-1.2	-0.6	-0.6	-0.5	-0.6
Reason for reducing amount of alcohol drunk: Health precaution	0.7	0.8	3.3	-1.1	0.3	-1.5	0.1	0.1	0.6	-0.9	-0.3	-0.5	-1.6	-1.8	-0.6	-0.2	-0.6	-0.6	-0.7	-1.4	-0.3	0.1
Ever had stillbirth, spontaneous miscarriage or termination	0.7	0.7	2.7	1.0	0.8	-0.2	1.4	-0.0	-1.2	0.6	0.7	0.8	1.6	1.3	0.2	0.5	0.5	1.2	0.4	0.3	0.9	-0.6
Qualifications: nursing, teaching	0.7	1.2	4.7	-1.3	-0.0	-1.5	-0.9	-0.6	0.4	-1.0	-0.4	-0.4	-1.8	-1.4	-1.2	-0.5	0.3	-1.0	-1.4	-0.9	-2.2	0.1
Medication: Gliclazide	0.7	0.8	3.9	0.9	1.6	-0.8	0.4	1.2	0.2	0.7	0.1	1.2	0.0	0.5	0.1	0.9	2.0	0.7	0.1	0.2	0.1	1.5
Supplements: Fish oil (including cod liver oil)	0.7	0.9	6.0	0.1	1.3	-0.9	-0.8	-1.4	0.4	-0.5	0.2	0.5	-0.9	-0.8	-0.5	0.7	2.4	0.8	-0.5	-1.4	-0.5	1.0
Ever smoked	0.7	1.1	3.5	0.4	-1.1	0.8	1.0	-0.1	-1.7	0.8	1.7	0.0	0.4	0.4	1.3	1.1	1.3	1.9	1.4	0.7	1.2	0.4
Diastolic blood pressure, automated reading	0.7	2.2	9.6	1.2	-0.7	1.9	1.7	0.7	-1.0	0.9	0.2	-0.7	2.4	2.7	1.9	-0.3	-0.8	0.4	1.9	0.8	3.1	-0.8
Supplements: Calcium	0.7	0.8	2.2	1.5	0.6	0.3	0.2	0.7	-0.9	0.9	1.0	0.7	0.4	0.0	0.9	1.4	1.4	1.3	0.9	0.5	0.4	1.2
Heart disease (siblings)	0.7	0.9	3.0	1.3	0.7	0.2	1.3	0.5	-1.0	0.7	0.7	1.5	0.7	1.7	0.6	1.0	1.3	1.1	0.8	0.1	0.4	0.3
Alzheimer’s Disease (in father)	0.6	0.6	3.6	-0.1	1.3	-1.2	-0.4	-0.6	0.6	-0.2	-0.8	1.2	-0.3	0.4	-1.0	0.2	1.9	0.6	-0.9	-0.6	-0.2	0.1
HbA1C	0.6	0.7	2.2	-0.4	-0.3	-0.5	-1.5	-0.4	0.7	-1.0	-0.7	0.1	-1.1	0.7	-0.8	-0.3	0.1	-0.9	-0.8	-1.1	-1.4	-0.8
Chronotype (morning person)	0.6	1.4	6.3	-1.2	-2.3	-2.2	-0.2	-0.6	0.3	-0.9	-0.6	-2.5	0.4	-0.5	0.0	-1.3	-1.7	-1.2	-0.2	0.0	-0.3	-1.3
Sensitivity / hurt feelings	0.6	1.0	2.9	-0.8	0.4	-1.2	-1.5	-1.3	1.7	-0.4	-1.6	-0.7	1.2	1.1	-0.8	-0.6	-0.5	-1.1	-0.8	0.5	-0.5	-0.5
Alcohol usually taken with meals	0.6	1.0	4.7	-0.8	-1.3	-1.3	-1.3	-0.5	0.7	-1.0	-0.8	-2.2	-0.6	-0.5	-0.4	-1.5	-0.8	-1.1	-0.7	-0.6	-0.4	-1.0
Suffer from ‘nerves’	0.6	0.9	2.9	-0.7	0.7	-1.3	-1.2	-1.7	1.3	-0.5	-1.2	-0.1	0.0	-0.8	-1.4	-1.1	-1.1	-0.9	-1.0	-0.5	-0.5	0.1
Mother’s age at death	0.6	0.8	3.4	-0.6	0.5	-1.9	-1.0	0.4	1.1	-0.5	-0.6	-0.5	-0.7	-1.3	-0.6	-0.2	1.4	-0.2	-0.8	-0.2	-0.9	1.2
Financial situation satisfaction	0.6	0.8	5.2	-0.6	-2.3	-0.0	0.3	-0.4	-0.8	-0.3	0.6	-1.6	-0.4	0.1	0.3	-0.7	-1.3	-0.2	0.4	0.7	-0.3	-1.3
High cholesterol (Self-reported)	0.6	1.1	5.6	-0.6	-2.4	0.4	1.6	-0.1	-1.9	-0.6	0.9	-0.7	-0.0	-0.3	0.1	-0.3	-0.8	0.6	0.5	-0.2	0.1	-2.4
Illnesses of father: High blood pressure	0.6	0.7	3.7	0.3	0.1	1.1	0.1	1.0	0.1	0.5	0.4	0.2	1.9	1.5	0.6	0.1	-1.4	-0.6	0.6	1.0	0.9	0.1
Alcohol drinker status: Never	0.6	0.7	3.2	-0.3	1.1	-0.6	-0.4	-0.7	0.7	-0.2	0.1	1.8	-0.7	-1.1	-0.3	0.6	1.1	0.3	-0.4	-1.2	0.4	1.4
Basal cell carcinoma (self-reported)	0.6	0.8	3.0	1.0	0.5	0.9	-0.2	0.6	-0.4	1.0	0.8	1.3	0.9	1.7	1.0	0.8	-0.0	0.5	0.9	1.1	0.8	0.5
Verbal and Numeric Reasoning (VNR)	0.5	1.2	3.0	-0.7	1.5	-1.0	-0.2	-0.1	1.0	-1.0	-0.7	1.3	-1.2	-0.5	-1.6	-0.1	1.2	-0.5	-1.7	-1.7	-1.7	-0.1
Mean Putamen Volume	0.5	0.6	2.9	-0.3	-1.7	0.4	0.8	0.7	-0.6	0.2	0.3	-1.2	0.3	-0.5	0.8	-0.2	0.2	0.4	0.7	0.9	0.5	-1.4
Primary Biliary Cirrhosis	0.5	0.7	3.9	-0.5	-1.2	0.4	0.1	-0.4	-0.9	-1.1	0.5	-1.1	-2.0	-1.0	-0.0	-0.2	-0.4	-0.6	0.2	-1.3	-0.8	-0.8
Pack years adult smoking proportion	0.5	0.7	3.1	0.3	-1.1	1.8	0.1	-0.5	-0.5	0.4	0.2	-0.7	0.8	1.2	0.9	-0.3	-1.0	-0.1	1.1	0.8	0.9	-1.2
Multivitamins +/- minerals	0.5	0.6	5.1	-0.4	0.4	-0.6	-0.5	-2.3	0.2	-1.0	-0.1	0.3	-0.3	-0.3	-1.0	0.0	0.7	-0.1	-0.7	-1.1	-0.3	-0.7
Mouth/teeth dental problems	0.5	0.7	2.6	0.8	-0.2	-0.0	0.4	0.8	-0.2	1.0	0.8	-0.5	1.3	0.1	1.6	0.7	-0.6	0.6	1.0	0.7	1.3	1.1
Number of live births	0.5	0.7	3.3	-0.8	-1.5	0.8	1.2	-0.2	-0.8	-0.8	-0.1	-1.0	-0.7	-0.4	-0.2	-1.0	-1.1	-0.5	0.0	-0.0	0.0	-1.8
Pulse wave reflection index	0.5	0.7	1.4	0.4	1.0	0.1	0.8	-0.7	-0.8	0.9	1.2	0.6	0.9	0.9	1.2	1.2	0.3	0.9	0.8	0.3	0.8	0.0
Seen a psychiatrist for nerves, anxiety, tension or depression	0.5	0.7	2.3	-0.5	0.4	-0.1	-0.7	-0.2	1.0	-1.0	-1.1	0.3	-0.6	0.1	-1.5	-1.2	0.6	-1.2	-1.2	-0.6	-0.9	-0.1
Family relationship satisfaction	0.5	0.6	3.2	-1.2	-0.7	-0.1	-0.8	-1.8	0.5	-0.9	-0.6	0.0	-1.0	-0.7	-1.0	-0.9	-0.6	-0.1	-0.7	-0.8	-0.0	-0.8
Supplements: Vitamin C	0.5	0.6	2.5	-0.1	0.8	-0.6	-1.5	-1.4	0.8	-0.4	-0.5	-0.5	1.0	0.0	-0.3	0.0	1.6	0.0	-0.4	-0.3	0.1	0.3
Diabetes diagnosed by doctor	0.5	0.9	2.8	0.6	1.6	-0.1	-0.4	1.7	1.5	0.9	-0.6	1.1	1.0	1.5	0.2	0.5	-0.2	-0.2	0.1	0.3	1.0	1.2
Osteoporosis (self-reported)	0.5	0.6	2.1	1.2	0.5	0.3	0.7	0.0	-0.7	0.9	0.2	1.4	0.8	0.7	0.1	0.7	1.1	1.1	0.5	0.9	0.3	1.1
Average weekly champagne plus white wine intake	0.5	0.7	2.5	-0.8	-0.1	-1.6	-0.9	0.0	1.2	-0.4	-1.1	-1.2	-0.5	-0.7	-0.9	-0.8	0.1	-0.8	-0.9	0.2	-0.8	0.6
Pack years of smoking	0.5	0.8	2.9	0.6	-0.7	1.7	0.2	0.0	-0.6	0.7	0.3	-0.4	0.9	1.5	1.1	-0.1	-0.7	0.1	1.3	1.1	1.0	-0.9
Schizophrenia vs Biploar Disorder	0.4	0.5	2.6	0.9	-0.2	0.6	-0.6	-0.2	-0.2	0.7	0.7	-0.0	1.6	0.9	0.7	0.3	-0.3	-0.2	0.5	1.3	-0.1	1.1
Crohns Disease (2017)	0.4	1.0	2.7	-0.1	-0.3	-1.0	-0.2	0.6	0.6	-1.1	-1.2	-0.4	-0.7	0.5	-1.5	-1.3	-1.1	-1.4	-1.4	-0.5	-1.0	-1.6
Triglycerides	0.4	0.7	2.3	0.2	1.3	-0.3	1.5	-0.4	-0.8	0.7	0.9	0.9	0.8	0.7	0.9	1.4	0.8	0.9	0.9	0.1	0.6	0.4
Heel T-Score	0.4	3.1	11.8	2.2	2.1	-1.3	0.7	3.4	-0.0	1.4	-0.0	3.0	1.4	3.3	-0.5	1.3	-0.2	-0.5	-0.7	2.1	-1.9	-0.1
Qualifications: None of the above	0.4	0.9	2.7	-1.0	-0.3	-1.4	-0.7	-0.1	1.3	-0.8	-1.3	-1.6	-0.7	-0.5	-0.8	-1.3	-0.8	-1.3	-0.5	-0.7	0.2	-0.8
Illnesses of siblings	0.4	0.5	4.6	-1.0	-1.1	0.2	0.1	0.3	-0.2	-0.5	0.3	-1.0	-0.6	-2.1	-0.3	-0.3	-0.6	0.0	-0.3	0.2	-0.6	-0.4
Mouth/teeth dental problems: Dentures	0.4	0.6	3.2	0.0	-0.3	0.8	1.1	0.2	-0.3	-0.1	-0.7	0.7	0.0	1.6	-0.7	-0.9	-1.2	-0.3	-0.3	-0.0	0.2	-1.8
Medication: Cholesterol lowering	0.4	0.6	1.9	0.4	-1.4	0.5	0.3	0.1	-1.1	0.4	0.6	-1.1	0.8	0.6	0.8	0.1	-1.4	0.1	0.9	0.9	0.7	-1.0
Qualifications: O levels/GCSEs or equivalent	0.4	0.7	3.3	0.2	1.8	1.1	0.5	1.1	0.9	0.4	-0.5	1.7	0.9	1.0	-0.2	0.2	0.1	-0.2	-0.2	0.6	0.4	0.5
Medication for cholesterol, blood pressure or diabetes	0.4	0.6	2.1	-0.3	1.3	-0.3	-0.3	-0.5	0.2	-0.3	-0.0	1.3	-0.9	-1.5	-0.6	0.3	1.3	0.3	-0.6	-0.6	-0.9	1.0
Qualifications: College or University degree	0.4	1.2	4.4	1.3	1.7	-0.6	-0.1	0.5	-0.8	0.5	1.6	0.9	-0.6	-0.7	0.6	2.1	1.6	1.4	0.2	-0.1	-0.8	1.5
Commuting to job workplace: Car/motor vehicle	0.4	0.4	2.5	0.1	0.6	0.1	-0.7	0.1	1.0	0.6	-0.5	0.1	1.6	1.3	0.1	-0.1	-0.4	-0.4	0.3	0.5	1.1	-0.1
Illness, injury, bereavement, stress in last 2 years	0.4	0.4	2.8	-1.0	-0.4	-0.2	0.5	0.7	-0.1	-0.8	0.3	-0.4	-1.0	-1.7	-0.3	-0.1	-0.6	-0.4	-0.1	-0.2	-1.0	-0.3
Eye problems/disorders: Cataract	0.4	0.5	1.9	-0.0	0.2	0.1	-0.0	-1.2	-0.5	-0.6	0.2	1.4	-1.0	0.3	-0.3	0.4	1.1	0.8	-0.3	-1.1	0.3	-0.8
Age started oral contraceptive pill	0.4	0.5	2.6	-1.4	-0.6	-0.8	-0.1	-0.5	0.9	-0.6	-0.5	-1.1	0.0	-1.6	-0.3	-1.0	-0.5	-0.3	-0.4	-0.6	0.2	-0.3
Hair Pigment	0.3	9.8	25.5	4.0	2.3	3.4	2.0	4.8	-0.7	3.9	1.9	2.4	5.0	4.0	3.6	2.8	-0.1	1.3	3.0	3.8	2.4	3.1
Frequency of depressed mood in last 2 weeks	0.3	0.4	1.2	-0.9	-0.0	-0.6	-0.6	-0.4	0.7	-0.4	-0.9	-0.7	-0.0	-0.6	-0.8	-1.1	-0.8	-0.9	-0.6	0.3	-0.5	-0.6
Eye problems/disorders: Diabetes related eye disease	0.3	0.3	0.9	0.6	0.8	0.1	0.3	0.4	0.2	0.6	0.6	0.8	0.7	0.2	0.8	0.7	0.3	0.7	0.6	0.2	1.0	0.6
Frequency of unenthusiasm / disinterest in last 2 weeks	0.3	0.4	1.8	-0.3	0.4	0.0	-1.1	-0.4	1.3	0.0	-1.3	-0.3	-0.2	-0.3	-0.6	-0.8	-0.2	-0.8	-0.5	0.3	-0.3	-0.2
Chronic bronchitis/emphysema (father)	0.3	0.4	3.4	0.3	-0.4	1.0	0.2	0.4	-0.4	0.2	0.5	0.7	0.2	0.5	0.2	0.1	-1.9	-0.2	0.4	0.1	0.1	-1.0
Past tobacco smoking	0.3	0.6	2.0	-0.2	0.9	-0.3	-1.4	-0.1	1.4	-0.2	-1.0	-0.0	-0.1	-0.5	-0.7	-0.3	-0.4	-1.3	-1.0	-0.0	-1.4	0.4
Frequency of tenseness / restlessness in last 2 weeks	0.3	0.5	3.0	0.5	0.1	1.1	-0.1	-0.7	-0.4	1.1	0.1	0.5	1.1	0.6	0.2	-0.1	0.4	0.5	0.7	1.7	1.0	-0.2
Heel bone mineral density (BMD) T-score, automated (right)	0.3	0.8	5.2	0.6	0.3	-0.7	-1.3	0.5	0.3	0.3	0.1	0.9	0.5	1.0	-0.5	0.4	-1.0	-1.1	-0.6	1.3	-2.3	0.5
Diabetes (self-reported)	0.3	0.5	2.7	0.2	1.0	-0.2	-0.4	1.6	1.3	0.7	-0.6	0.5	0.6	1.0	0.2	0.2	-0.2	-0.3	0.2	0.2	1.0	0.7
Medication: Simvastatin	0.3	0.5	2.4	-0.8	-1.2	-0.5	0.1	0.6	-0.0	-0.5	-0.2	-0.8	0.4	0.6	-0.2	-0.6	-1.6	-0.5	0.0	-0.5	0.7	-1.3
Fluid intelligence score	0.3	0.6	2.0	-0.8	-0.3	-1.2	-0.5	0.5	0.5	-0.7	-0.5	-0.2	-0.7	0.5	-0.9	-0.4	0.4	-0.7	-1.2	-0.5	-1.4	-0.8
Noisy workplace	0.3	0.4	1.8	0.9	0.1	-0.4	-0.2	-0.6	-0.3	0.6	-0.0	-0.1	0.9	1.2	0.4	-0.1	-1.3	-0.3	0.4	0.6	0.5	-0.6
Tense / ‘highly strung’	0.3	0.5	1.5	-0.2	0.9	-0.9	-0.4	-0.2	1.2	-0.3	-1.1	-0.2	0.6	0.0	-0.9	-0.8	-0.8	-0.7	-0.7	0.1	0.1	-0.7
Ever highly irritable/argumentative for 2 days	0.3	0.3	1.0	-0.3	0.9	-0.6	0.0	-0.6	0.7	0.4	-1.0	0.6	0.5	-0.1	-0.9	-0.1	0.6	0.0	-0.7	0.7	-0.6	0.3
Loud music exposure frequency	0.3	0.4	2.0	-0.5	-1.4	0.4	-0.7	-0.3	-0.3	0.1	0.6	-0.9	-0.8	-0.5	0.2	0.1	-0.7	-0.0	-0.0	0.8	-0.7	-0.5
Mouth/teeth dental problems: Bleeding gums	0.3	0.4	1.5	-1.0	-0.3	-0.4	-0.7	-0.4	0.5	-0.7	-0.6	-0.6	-1.0	-0.9	-0.8	-0.4	0.1	-0.8	-0.5	0.0	-1.2	-0.0
Glaucoma (self-reported)	0.3	0.4	2.3	-0.0	-0.2	0.0	-0.0	0.8	0.6	0.1	-0.6	-0.6	0.6	1.5	0.5	-0.3	-0.8	-0.1	0.1	-0.3	1.1	-1.0
Medication: Blood pressure	0.3	0.5	3.1	0.5	0.1	1.3	0.8	1.0	0.2	0.5	-0.5	0.1	0.9	1.8	0.3	-0.3	-0.6	-0.1	0.5	0.3	0.9	-0.4
Medication: Allopurinol	0.3	0.4	1.8	0.3	-0.3	-0.8	-0.9	-0.3	0.3	-0.4	-0.7	-1.3	-0.2	1.3	-0.0	-0.4	0.2	-0.9	-0.2	-0.0	-0.5	-0.4
Medication: Seretide 50 evohaler	0.3	0.4	1.0	0.6	-0.2	0.6	0.2	1.0	-0.5	0.2	0.6	-0.0	-0.6	-0.1	0.6	0.9	0.8	0.6	0.8	-0.4	0.2	1.0
Illnesses of father: Heart disease	0.3	0.5	1.5	0.5	-0.7	0.6	0.6	1.2	-0.7	0.1	0.4	-0.0	0.2	0.8	1.2	0.6	-0.1	0.8	0.8	-0.1	1.2	-0.4
Mouth/teeth dental problems: Mouth ulcers	0.3	0.5	1.8	-0.6	1.0	-0.6	-0.1	-1.4	0.1	-0.6	-0.2	1.1	-0.5	-0.8	-1.0	0.2	0.8	0.3	-0.8	-0.8	-0.5	-0.2
Wears glasses or contact lenses	0.3	0.3	1.0	0.8	0.3	0.9	-0.6	0.8	-0.2	0.3	0.7	0.5	-1.0	-0.1	0.8	0.7	-0.3	0.3	0.5	0.2	-0.3	0.7
Intelligence (Savage-Jansen 2018)	0.2	0.7	1.7	0.1	1.0	-0.1	1.3	0.2	-0.5	-0.5	0.2	1.1	-0.4	1.0	-0.9	0.6	1.2	0.5	-1.2	-0.9	-0.9	-1.1
Reaction Time	0.2	0.5	3.3	-0.3	-1.8	0.3	-0.3	-0.3	-0.4	0.2	0.1	-1.3	-0.2	0.1	0.2	-0.4	-1.6	0.0	0.4	0.4	-0.3	-0.4
Tanning	0.2	2.3	4.1	-1.8	-1.4	-2.0	-1.1	-1.6	0.8	-1.1	-1.3	-1.7	-1.6	-1.5	-1.8	-1.7	-1.9	-1.5	-1.3	-0.7	-1.7	-1.1
Hearing difficulty/problems: Yes	0.2	0.3	1.0	0.4	-0.4	-0.1	0.4	0.4	-0.2	0.6	0.3	-0.1	0.5	0.5	0.7	0.2	-1.0	0.1	0.8	0.6	0.7	0.3
Medication: Metformin	0.2	0.3	2.0	0.1	0.8	0.6	0.3	1.4	0.8	0.3	-0.3	0.7	0.2	0.9	0.0	0.3	-0.2	-0.4	-0.0	-0.5	0.6	0.3
Had menopause	0.2	0.3	0.6	0.4	0.6	-0.5	0.6	0.8	-0.2	0.6	0.0	-0.1	-0.3	-0.4	0.6	0.5	0.7	0.6	0.4	0.1	0.3	0.8
Happiness	0.2	0.3	1.1	0.1	0.7	0.4	-1.1	-1.0	0.9	0.3	-0.4	0.0	-0.0	-0.5	-0.4	-0.5	-0.5	0.0	-0.2	0.5	0.4	0.4
Breastfed as a baby	0.2	0.2	1.5	0.3	0.2	-0.5	-0.8	0.1	0.3	0.6	0.1	-0.1	0.1	-0.3	0.5	0.2	0.1	0.2	0.6	0.7	0.7	1.2
Blood clot in the leg (DVT)	0.2	0.2	1.3	0.2	0.4	0.4	-0.2	-0.6	0.3	0.4	-0.3	0.7	0.1	0.6	0.3	0.3	0.1	0.2	0.3	-0.1	1.1	0.4
Alcohol intake frequency.	0.2	0.5	2.0	-1.0	0.2	-0.9	-0.8	-0.8	1.0	-0.9	-0.7	-0.1	-0.6	0.2	-0.5	-0.8	0.4	-0.9	-0.8	-1.4	0.0	-0.1
Smoking status: Previous	0.2	0.4	1.0	-0.6	-0.9	-0.8	0.9	-0.1	-0.5	-0.6	-0.1	-0.4	-0.3	-0.1	-0.3	-0.7	-0.6	0.2	0.1	-0.6	0.9	-1.0
Miserableness	0.2	0.3	1.9	0.2	0.1	0.8	-0.2	-0.0	-0.3	0.7	0.3	0.4	0.7	1.2	0.1	0.4	0.1	0.4	0.4	1.4	-0.1	0.1
Commuting to job workplace: Public transport	0.2	0.3	1.3	-0.5	-0.7	0.0	0.1	0.1	-0.0	-0.4	-0.4	-0.3	-0.6	-0.1	-0.5	-0.7	-0.8	-0.6	-0.7	-0.0	-0.6	-1.1
Medication: Atorvastatin	0.2	0.2	1.5	0.5	-0.3	0.1	0.2	-0.4	-0.7	0.2	-0.0	0.7	-0.2	0.2	-0.1	0.4	1.2	0.9	0.0	0.2	-0.4	-0.1
Average weekly beer plus cider intake	0.2	0.2	1.1	0.6	0.6	1.0	-0.8	-0.8	-0.0	0.1	0.2	0.4	-0.4	0.2	-0.1	0.6	0.4	-0.3	0.0	0.3	-0.5	0.4
Irritability	0.2	0.4	1.0	-0.0	1.0	-0.1	0.3	0.1	0.1	-0.2	-0.7	0.8	0.7	0.9	-0.9	-0.5	-1.0	-0.3	-0.3	-0.4	0.0	-0.9
Pulse wave peak to peak time	0.1	0.1	1.1	0.4	-0.3	-0.0	0.2	1.1	-0.2	-0.3	-0.1	-0.7	0.2	-0.1	0.4	0.2	-0.2	0.0	0.2	0.4	0.2	-0.1
Mean time to correctly identify matches	0.1	0.2	0.7	-0.5	-0.9	0.7	-0.3	-0.4	0.0	0.1	-0.1	-0.4	-0.8	-0.5	0.0	-0.3	-0.8	0.0	0.2	-0.1	-0.2	0.1
Illnesses of father: None of the above (group 1)	0.1	0.2	0.8	0.1	-0.5	-0.8	0.5	0.3	-0.5	0.4	0.1	-0.1	0.6	0.3	-0.3	-0.1	0.1	0.1	-0.0	0.9	-0.3	-0.2
Deep venous thrombosis (DVT) (self-reported)	0.1	0.2	0.8	0.1	0.4	0.5	-0.3	-0.6	0.3	0.3	-0.4	0.6	0.1	0.6	0.3	0.2	0.1	-0.0	0.2	-0.0	0.9	0.4
Prostate Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0

Hub : Genes

C6orf106

Models

Trait associations