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chr11:77,231,939-78,828,001
Best TWAS P=5.2e-08 · Best GWAS P=1.2e-07 conditioned to 1
77.2M
77.4M
77.6M
77.8M
78M
78.2M
78.4M
78.6M
78.8M
0
2
4
6
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
4
The Cancer Genome Atlas
Prostate Adenocarcinoma
GAB2
0.06
0.06
blup
100
0.07
7.8e-08
5.1
-5.4
5.2e-08
-0.95
0.05
0.95
TRUE
3
The Cancer Genome Atlas
Glioblastoma Multiforme
GAB2
0.10
0.07
blup
100
0.09
8.8e-04
4.9
-5.4
7.7e-08
-0.94
0.05
0.65
FALSE
2
GTEx
Esophagus Muscularis
GAB2
0.05
0.04
lasso
7
0.04
1.8e-03
5.1
-5.4
7.8e-08
-0.83
0.08
0.86
FALSE
1
GTEx
Artery Tibial
GAB2
0.06
0.00
lasso
2
0.01
2.4e-02
5.1
-5.1
2.7e-07
-0.96
0.08
0.71
FALSE
5
The Cancer Genome Atlas
Stomach Adenocarcinoma
GAB2
0.04
0.04
blup
100
0.04
1.4e-03
4.2
-5.1
2.7e-07
-0.95
0.08
0.80
FALSE