Best TWAS P=5.2e-08 · Best GWAS P=1.2e-07 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | GAB2 | 0.06 | 0.00 | lasso | 2 | 0.01 | 2.4e-02 | 5.1 | -5.1 | 2.7e-07 | -0.96 | 0.08 | 0.71 | FALSE |
| 2 | GTEx | Esophagus Muscularis | GAB2 | 0.05 | 0.04 | lasso | 7 | 0.04 | 1.8e-03 | 5.1 | -5.4 | 7.8e-08 | -0.83 | 0.08 | 0.86 | FALSE |
| 3 | The Cancer Genome Atlas | Glioblastoma Multiforme | GAB2 | 0.10 | 0.07 | blup | 100 | 0.09 | 8.8e-04 | 4.9 | -5.4 | 7.7e-08 | -0.94 | 0.05 | 0.65 | FALSE |
| 4 | The Cancer Genome Atlas | Prostate Adenocarcinoma | GAB2 | 0.06 | 0.06 | blup | 100 | 0.07 | 7.8e-08 | 5.1 | -5.4 | 5.2e-08 | -0.95 | 0.05 | 0.95 | TRUE |
| 5 | The Cancer Genome Atlas | Stomach Adenocarcinoma | GAB2 | 0.04 | 0.04 | blup | 100 | 0.04 | 1.4e-03 | 4.2 | -5.1 | 2.7e-07 | -0.95 | 0.08 | 0.80 | FALSE |