Best TWAS P=1.15e-09 · Best GWAS P=1.7e-09 conditioned to 0.00137
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Visceral Omentum | TRPT1 | 0.16 | 0.05 | lasso | 5 | 0.04 | 3.0e-03 | -3.7 | -5.2 | 2.1e-07 | 0.04 | 0.02 | 0.81 | FALSE |
| 2 | GTEx | Colon Transverse | DPF2 | 0.19 | 0.01 | lasso | 4 | 0.05 | 1.6e-03 | -3.7 | -5.1 | 3.0e-07 | 0.52 | 0.07 | 0.25 | FALSE |
| 3 | GTEx | Esophagus Mucosa | FKBP2 | 0.09 | 0.02 | enet | 18 | 0.05 | 2.6e-04 | 3.8 | -6.0 | 2.1e-09 | 0.03 | 0.05 | 0.92 | TRUE |
| 4 | GTEx | Nerve Tibial | TRPT1 | 0.14 | 0.03 | lasso | 6 | 0.07 | 1.8e-05 | -4.9 | -5.4 | 6.2e-08 | 0.01 | 0.02 | 0.97 | FALSE |
| 5 | METSIM | Adipose | RNASEH2C | 0.07 | 0.03 | blup | 325 | 0.04 | 3.4e-07 | -3.1 | 6.1 | 1.1e-09 | -0.50 | 0.79 | 0.08 | TRUE |
| 6 | The Cancer Genome Atlas | Thyroid Carcinoma | PRDX5 | 0.05 | 0.04 | lasso | 3 | 0.02 | 1.6e-03 | -5.1 | 5.1 | 2.9e-07 | -0.04 | 0.00 | 0.93 | FALSE |