[Hub]/) : Traits : Current tobacco smoking : ←

chr22:41,181,586-42,907,619

Best TWAS P=8.37e-10 · Best GWAS P=3.33e-08 conditioned to 0.215

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	MEI1	0.09	0.10	blup	343	0.10	3.1e-12	-4.6	-5.6	2.7e-08	-0.64	0.27	0.72	FALSE
2	GTEx	Adipose Subcutaneous	CCDC134	0.05	0.02	lasso	4	0.01	2.1e-02	5.1	-5.3	1.4e-07	-0.94	0.05	0.80	FALSE
3	GTEx	Artery Aorta	ACO2	0.08	0.08	lasso	5	0.06	2.8e-04	-5.1	-5.3	1.0e-07	-0.58	0.05	0.88	FALSE
4	GTEx	Breast Mammary Tissue (Male)	CCDC134	0.08	-0.01	enet	1	0.00	3.4e-01	5.1	-5.1	2.9e-07	-0.93	0.03	0.19	FALSE
5	GTEx	Muscle Skeletal	ACO2	0.07	0.02	lasso	4	0.02	6.9e-03	5.5	5.4	6.0e-08	0.99	0.01	0.96	FALSE
6	GTEx	Stomach	DESI1	0.12	0.07	enet	14	0.06	4.9e-04	-4.9	-5.3	1.4e-07	-0.67	0.12	0.85	FALSE
7	The Cancer Genome Atlas	Breast Invasive Carcinoma	MEI1	0.01	0.01	blup	62	0.01	1.1e-02	-4.6	-5.5	4.8e-08	-0.62	0.02	0.88	FALSE
8	The Cancer Genome Atlas	Colon Adenocarcinoma	MEI1	0.05	0.00	blup	64	0.03	1.1e-02	-4.6	-5.5	3.9e-08	-0.69	0.01	0.40	FALSE
9	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	MEI1	0.03	0.01	blup	64	0.02	3.8e-03	-4.7	-5.3	1.1e-07	-0.66	0.02	0.78	FALSE
10	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	ACO2	0.03	0.01	blup	41	0.04	3.9e-03	5.5	-5.8	5.2e-09	-0.71	0.02	0.60	FALSE
11	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	PHF5A	0.03	0.00	blup	30	0.01	2.9e-02	-5.0	-6.1	8.4e-10	-0.77	0.01	0.59	TRUE
12	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	PMM1	0.02	0.01	blup	19	0.02	4.0e-03	-4.6	5.3	1.1e-07	0.61	0.01	0.66	FALSE
13	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	TOB2	0.03	0.00	blup	28	0.02	3.4e-03	-5.1	-6.1	1.1e-09	-0.68	0.01	0.58	FALSE
14	The Cancer Genome Atlas	Testicular Germ Cell Tumors	POLR3H	0.10	0.02	blup	23	0.06	3.4e-03	-5.0	5.8	5.8e-09	0.72	0.02	0.61	FALSE