TWAS hub - POLR3H

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.2370	0.0550	0.0e+00	0.310	0.342	0.352	0.348	0.352	1.9e-38	5.3e-43	1.3e-44	6.1e-44	1.7e-44
2	GTEx	Adipose Subcutaneous	0.1160	0.0410	1.3e-04	0.035	NA	0.063	NA	0.062	6.8e-04	NA	6.7e-06	NA	8.3e-06
3	GTEx	Artery Aorta	0.1250	0.0610	4.2e-03	0.041	NA	0.037	NA	0.044	2.4e-03	NA	3.9e-03	NA	1.9e-03
4	GTEx	Brain Cerebellar Hemisphere	0.0960	0.0500	9.4e-03	0.077	NA	0.062	NA	0.078	5.0e-03	NA	1.1e-02	NA	4.9e-03
5	GTEx	Brain Cortex	0.2670	0.0980	4.3e-06	0.212	NA	0.142	NA	0.184	1.6e-06	NA	9.7e-05	NA	8.5e-06
6	GTEx	Brain Frontal Cortex BA9	0.1258	0.0704	6.5e-03	0.089	NA	0.028	NA	0.039	2.4e-03	NA	6.0e-02	NA	3.4e-02
7	GTEx	Brain Hippocampus	0.1622	0.0833	2.9e-03	0.112	NA	0.028	NA	0.052	1.4e-03	NA	7.3e-02	NA	2.4e-02
8	GTEx	Brain Putamen basal ganglia	0.2300	0.1160	2.7e-03	0.058	NA	0.038	NA	0.032	1.7e-02	NA	4.5e-02	NA	6.0e-02
9	GTEx	Breast Mammary Tissue	0.1550	0.0710	8.1e-03	0.019	NA	0.032	NA	0.012	3.7e-02	NA	9.0e-03	NA	7.8e-02
10	GTEx	Breast Mammary Tissue (Female)	0.0928	0.0650	6.6e-02	-0.008	NA	-0.010	NA	-0.008	6.9e-01	NA	9.7e-01	NA	6.4e-01
11	GTEx	Cells Transformed fibroblasts	0.1030	0.0430	2.7e-04	0.065	NA	0.024	NA	0.047	1.3e-05	NA	6.3e-03	NA	1.8e-04
12	GTEx	Colon Sigmoid	0.2460	0.1090	3.2e-03	-0.004	NA	0.015	NA	-0.007	5.0e-01	NA	9.1e-02	NA	6.5e-01
13	GTEx	Muscle Skeletal	0.1685	0.0547	8.0e-07	0.118	NA	0.105	NA	0.109	1.3e-11	NA	1.8e-10	NA	8.0e-11
14	GTEx	Nerve Tibial	0.0942	0.0431	1.3e-03	0.082	NA	0.045	NA	0.063	2.0e-06	NA	3.8e-04	NA	3.2e-05
15	GTEx	Pancreas	0.1390	0.0720	2.4e-03	-0.002	NA	0.032	NA	0.016	3.9e-01	NA	1.7e-02	NA	6.6e-02
16	GTEx	Testis	0.3190	0.0810	0.0e+00	0.512	NA	0.512	NA	0.511	5.7e-26	NA	5.6e-26	NA	6.9e-26
17	GTEx	Thyroid	0.0610	0.0290	4.8e-03	0.018	NA	0.003	NA	0.001	1.6e-02	NA	1.9e-01	NA	2.7e-01
18	TCGA	Head and Neck Squamous Cell Carcinoma	0.0438	0.0269	2.0e-05	0.038	0.035	0.029	NA	0.029	3.8e-05	6.8e-05	2.7e-04	NA	3.1e-04
19	TCGA	Lung Adenocarcinoma	0.0259	0.0167	1.9e-03	0.014	0.006	-0.002	NA	0.001	8.3e-03	6.4e-02	9.6e-01	NA	2.5e-01
20	TCGA	Prostate Adenocarcinoma	0.0426	0.0238	2.3e-05	0.048	0.052	0.036	NA	0.044	8.0e-06	3.4e-06	1.1e-04	NA	1.8e-05
21	TCGA	Stomach Adenocarcinoma	0.0390	0.0330	3.0e-03	0.058	0.021	0.037	NA	0.042	4.9e-05	1.1e-02	1.1e-03	NA	4.8e-04
22	TCGA	Testicular Germ Cell Tumors	0.0990	0.0680	8.6e-04	0.019	0.061	0.036	NA	0.036	6.9e-02	3.4e-03	2.0e-02	NA	2.0e-02

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22
Basal cell carcinoma (self-reported)	10.2	12.2	23.6	4.6	-0.8	-0.2	3.9	4.0	4.0	4.1	3.3	-2.7	-0.7	-2.6	-3.4	-3.9	-2.6	-3.4	4.0	-1.5	-4.5	-4.9	-4.9	-3.8	-3.3
Respiratory disease	8.8	19.7	38.1	5.0	2.7	4.5	6.1	6.0	6.1	6.0	4.3	2.0	2.6	-1.0	-3.3	-0.1	-0.5	-2.8	6.0	2.3	-5.1	-5.1	-5.2	-5.2	-6.2
Current tobacco smoking	8.7	14.3	33.9	-4.0	-1.9	-5.0	-4.9	-4.9	-4.9	-5.0	-3.3	-3.2	-3.2	-0.4	0.7	-0.8	-0.9	-0.4	-4.7	-2.7	3.9	4.3	4.3	4.6	5.8
Allergy	8.0	18.4	36.6	-4.9	-2.1	-4.6	-5.5	-5.5	-5.5	-5.6	-4.2	-1.9	-3.2	1.0	3.5	0.2	0.5	2.9	-5.5	-2.1	4.4	5.2	5.6	5.6	6.0
Maternal smoking around birth	7.7	11.2	20.3	-4.4	0.9	-1.8	-4.5	-4.3	-4.5	-4.5	-3.8	-0.7	-0.4	2.3	2.4	1.6	1.9	2.9	-4.2	0.4	4.0	3.9	4.0	4.3	4.3
Asthma (self-reported)	7.7	15.4	27.4	4.6	1.4	3.5	5.2	5.2	5.2	5.2	4.3	1.0	1.6	-1.9	-3.6	-0.8	-1.3	-3.4	5.1	1.1	-4.6	-4.7	-4.7	-4.8	-5.2
Medication: Ventolin 100micrograms inhaler	7.4	9.5	16.6	3.7	0.7	2.4	4.1	4.0	4.1	4.1	3.8	0.1	0.6	-2.1	-2.4	-0.8	-1.7	-2.8	3.9	0.7	-3.5	-3.7	-3.9	-3.8	-3.8
Asthma	7.3	14.3	25.7	4.5	1.4	3.5	5.0	5.0	5.1	5.1	4.0	0.8	1.4	-1.9	-3.4	-0.7	-1.3	-3.3	4.9	1.3	-4.4	-4.5	-4.6	-4.5	-5.0
Smoking status: Current	7.0	11.1	26.6	-3.2	-2.1	-4.8	-4.1	-4.2	-4.1	-4.2	-2.7	-3.5	-3.3	-0.8	0.3	-1.2	-1.4	-0.9	-4.0	-2.7	3.2	3.6	3.6	4.1	5.2
Blood Eosinophil Count	6.8	52.1	98.2	9.7	1.2	3.4	9.7	9.7	9.7	9.9	7.5	-0.5	-0.7	-4.3	-4.3	-4.2	-3.4	-6.0	9.6	1.5	-8.9	-9.3	-9.9	-7.9	-8.9
Allergy or Eczema	6.8	17.8	33.8	5.2	0.7	3.5	5.6	5.6	5.6	5.7	4.8	0.7	2.2	-1.7	-3.2	-1.2	-1.3	-3.0	5.4	1.3	-4.5	-5.1	-5.6	-5.4	-5.8
Impedance of arm (left)	6.5	30.0	54.0	7.2	0.6	2.0	7.3	6.9	7.3	7.3	6.1	-2.5	-1.3	-4.8	-5.5	-3.7	-3.7	-4.7	6.9	-0.7	-6.4	-5.9	-6.4	-6.4	-6.4
Neuroticism (Nagel 2018)	6.3	14.8	29.2	5.0	0.6	2.1	5.2	5.1	5.1	5.4	3.8	-0.8	1.2	-1.0	-3.1	-2.3	-0.5	-1.8	5.1	0.9	-5.0	-5.1	-5.0	-4.7	-5.1
Mood swings	6.2	11.1	20.8	4.3	0.6	2.1	4.2	4.4	4.2	4.6	3.1	-1.1	1.9	-0.8	-3.5	-1.8	-0.6	-2.5	4.4	0.9	-4.2	-4.4	-4.3	-4.0	-4.2
Smoking Status	5.9	14.1	31.4	-3.0	-3.2	-5.6	-4.2	-4.4	-4.2	-4.3	-2.9	-4.8	-5.1	-2.2	0.2	-2.1	-2.5	-0.7	-4.4	-4.1	3.0	3.2	3.1	4.1	5.4
Hypothyroidism (self reported)	5.9	13.6	22.9	-4.7	0.6	-0.6	-4.5	-4.5	-4.5	-4.7	-4.5	1.7	-1.0	2.4	4.8	3.1	2.2	3.8	-4.3	1.0	4.8	4.3	4.2	4.2	4.0
Impedance of arm (right)	5.8	27.2	48.7	6.9	0.4	1.4	7.0	6.5	6.9	6.9	5.7	-2.8	-2.1	-4.8	-5.0	-4.0	-3.7	-4.5	6.5	-1.1	-6.0	-5.6	-6.3	-6.0	-5.9
Hayfever, allergic rhinitis or eczema	5.6	12.2	23.0	4.2	0.8	3.2	4.4	4.5	4.5	4.5	4.0	1.0	2.2	-1.4	-2.9	-0.8	-1.0	-2.6	4.4	0.8	-3.5	-4.3	-4.7	-4.7	-4.8
Medication: Levothyroxine sodium	5.6	9.5	17.0	-3.7	0.5	-0.3	-3.7	-3.8	-3.7	-3.7	-3.9	1.6	-1.0	2.1	4.1	2.6	2.0	3.3	-3.7	1.1	4.0	3.6	3.5	3.4	3.1
Hypothyroidism/myxoedema (self-reported)	5.6	10.9	18.4	-4.3	1.2	0.3	-3.9	-3.8	-3.9	-4.0	-4.0	2.1	-0.2	2.6	4.0	3.4	2.6	3.8	-3.8	1.5	4.3	3.7	3.6	3.4	3.1
Serious illness, injury or assault of a close relative in last 2 years	5.5	6.3	11.0	-2.9	1.2	-0.3	-3.2	-3.2	-3.1	-3.2	-2.6	1.0	-0.2	1.2	2.9	2.2	0.8	3.2	-3.1	1.5	3.3	2.9	2.6	2.8	2.9
Irritability	5.5	9.3	16.5	3.8	0.5	1.7	3.8	4.1	3.8	4.0	3.7	-0.7	2.0	-1.1	-2.5	-1.6	-1.1	-2.2	4.0	1.0	-4.0	-4.1	-3.8	-3.7	-3.7
Tense / ‘highly strung’	5.0	8.2	15.5	3.8	0.3	1.6	3.7	3.9	3.8	3.9	3.0	-0.5	1.4	-1.2	-2.2	-2.0	-0.7	-1.6	3.6	0.1	-3.6	-3.9	-3.9	-3.3	-3.8
Depressed Affect (Nagel 2018)	4.8	10.2	18.9	3.6	2.0	2.5	4.1	4.2	4.0	4.2	2.8	0.4	2.1	-0.1	-3.5	-1.1	0.3	-2.0	4.3	1.2	-4.0	-4.1	-3.8	-4.0	-4.3
Trunk fat percentage	4.8	19.4	38.2	5.4	0.4	2.3	5.6	5.7	5.6	5.7	4.9	0.4	2.4	-1.5	-4.5	-2.0	-1.0	-3.2	5.6	0.8	-6.2	-6.0	-5.3	-5.5	-5.5
Impedance of whole body	4.6	23.3	42.2	6.5	0.4	1.8	6.5	6.1	6.5	6.5	5.2	-2.1	-1.7	-4.7	-4.5	-3.2	-3.7	-4.0	6.1	-0.3	-5.5	-5.1	-5.7	-5.7	-5.6
Fed-up feelings	4.4	7.9	15.3	3.1	1.8	2.4	3.5	3.7	3.5	3.7	3.0	0.6	2.0	-0.3	-3.0	-0.6	0.2	-1.9	3.7	0.7	-3.4	-3.5	-3.3	-3.7	-3.9
Qualifications: NVQ or HND or HNC or equivalent	4.4	5.3	9.1	-2.7	1.3	-0.2	-2.5	-2.4	-2.4	-2.4	-1.8	1.1	0.8	3.0	3.0	2.0	2.8	2.9	-2.4	1.4	2.5	2.8	3.0	2.5	2.0
Number of self-reported non-cancer illnesses	4.3	7.4	20.2	1.9	2.7	4.5	3.2	3.1	3.2	3.2	1.4	3.0	3.4	2.0	-0.3	1.9	2.6	0.3	3.2	2.9	-2.3	-2.4	-2.2	-2.2	-4.0
Neuroticism score	4.2	8.7	17.5	4.0	-0.1	1.8	3.8	4.0	3.9	4.2	2.9	-0.8	0.9	-1.2	-2.1	-1.8	-0.8	-1.1	3.7	0.3	-3.7	-4.0	-4.0	-3.6	-3.9
Frequency of tiredness / lethargy in last 2 weeks	4.2	6.9	14.0	2.9	1.9	2.7	3.1	3.5	3.2	3.4	2.6	0.5	2.5	0.4	-1.6	-0.3	0.7	-0.6	3.4	1.8	-2.9	-3.4	-3.2	-3.6	-3.7
Mean time to correctly identify matches	4.2	8.1	14.1	-3.5	-0.1	-1.2	-3.4	-3.7	-3.5	-3.4	-3.5	0.6	-2.6	1.5	2.8	1.0	2.2	2.4	-3.8	-1.0	3.7	3.5	3.1	3.6	3.1
Average weekly spirits intake	4.0	5.0	9.5	-2.8	0.5	-0.6	-3.0	-3.0	-3.0	-2.9	-2.5	-0.1	0.1	1.4	1.5	1.6	1.5	1.0	-2.9	0.3	3.0	2.8	2.7	3.1	2.8
Neuroticism	3.9	9.5	19.3	4.2	0.1	1.3	4.1	4.0	4.1	4.4	2.8	-1.2	0.8	-1.1	-2.6	-2.3	-0.9	-1.4	3.9	0.7	-4.2	-4.1	-4.0	-3.5	-3.9
Mouth/teeth dental problems: Loose teeth	3.9	4.6	9.4	-2.5	-0.7	-1.8	-2.8	-3.1	-2.8	-2.8	-2.5	-0.7	-1.8	0.5	1.8	0.4	0.3	1.3	-2.9	-0.9	2.5	2.4	2.3	2.7	2.9
Body fat percentage	3.8	14.9	32.1	4.7	0.1	1.6	4.9	5.0	4.9	5.0	4.1	0.3	2.0	-1.2	-4.2	-2.1	-0.8	-2.9	4.9	0.5	-5.7	-5.4	-4.7	-4.6	-4.7
Worrier / anxious feelings	3.6	6.8	13.2	3.5	-0.1	1.9	3.4	3.4	3.4	3.6	2.4	-0.2	0.9	-0.5	-1.8	-1.3	-0.4	-0.8	3.3	0.9	-3.2	-3.6	-3.6	-3.5	-3.6
Worry (Nagel 2018)	3.5	7.5	15.1	3.9	-0.8	0.3	3.5	3.4	3.5	3.8	2.6	-2.1	-0.1	-1.4	-1.8	-3.0	-1.4	-0.9	3.4	-0.0	-3.7	-3.7	-3.6	-3.2	-3.1
Neuroticism (2016)	3.5	5.1	10.0	3.0	-1.3	0.9	3.0	2.3	2.5	3.0	1.8	-1.3	0.3	-1.7	-1.8	-1.8	-1.6	-1.9	2.5	-0.6	-2.8	-3.2	-3.1	-3.1	-2.6
Medication: Atenolol	3.5	4.4	8.1	-2.6	1.0	0.8	-2.0	-2.1	-2.1	-2.1	-1.3	1.3	1.1	2.8	2.5	2.3	2.8	2.7	-2.1	1.7	2.4	2.3	2.3	2.3	1.4
Glaucoma (self-reported)	3.5	4.1	8.6	2.9	-0.9	-0.4	2.3	2.2	2.4	2.5	1.7	-1.2	-1.8	-2.2	-1.7	-2.3	-1.9	-1.6	2.1	-0.8	-2.3	-2.5	-2.9	-2.0	-1.8
Crohns Disease (2017)	3.4	7.5	13.7	3.0	1.3	3.5	3.6	3.5	3.5	3.5	3.2	2.2	1.9	-1.0	-0.1	0.7	-0.8	-1.2	3.4	2.3	-2.8	-3.1	-3.2	-3.2	-3.7
Age at last live birth	3.4	5.0	10.6	2.5	-2.3	-1.2	1.8	2.1	1.8	1.9	2.7	-2.8	-1.4	-2.9	-2.6	-2.7	-2.4	-3.3	1.7	-2.3	-2.4	-2.2	-2.1	-1.5	-0.9
Diabetes (mother)	3.3	4.2	8.5	-2.5	1.1	-1.0	-2.4	-2.5	-2.4	-2.4	-2.9	-0.2	-0.7	2.4	0.8	1.2	2.2	1.5	-2.3	0.9	2.3	2.5	2.7	2.6	2.2
Friendships satisfaction	3.3	4.1	13.5	-1.3	2.9	3.0	-0.8	-0.5	-0.8	-0.6	-0.6	2.5	2.4	3.3	2.1	2.9	3.2	2.0	-0.4	3.7	1.6	0.8	0.8	0.1	-0.5
Happiness	3.2	3.9	12.9	-0.2	3.2	3.6	0.6	0.9	0.6	0.8	0.6	2.3	2.9	2.7	1.5	2.7	2.9	1.6	1.0	3.6	0.2	-0.6	-0.6	-0.8	-1.8
Number of children fathered	3.2	3.6	6.9	-2.3	0.5	-0.5	-2.2	-2.2	-2.1	-2.2	-2.0	0.5	0.5	2.3	1.7	1.4	1.7	2.5	-2.1	0.9	1.9	2.3	2.6	2.5	1.9
Illness, injury, bereavement, stress in last 2 years	3.2	3.9	11.6	1.6	-2.8	-2.6	1.2	1.0	1.1	1.1	1.6	-2.9	-1.9	-2.2	-2.5	-3.4	-2.1	-2.3	0.9	-2.9	-1.9	-1.3	-1.2	-0.5	-0.2
Arm fat percentage (left)	3.2	12.8	27.5	4.1	0.6	2.0	4.6	4.6	4.5	4.6	3.9	0.8	2.5	-0.5	-3.8	-1.4	-0.1	-2.7	4.5	0.7	-5.2	-5.0	-4.2	-4.3	-4.6
Supplements: Calcium	3.2	3.6	7.7	1.8	1.6	2.3	2.6	2.5	2.6	2.6	1.5	1.2	1.8	0.5	-1.2	0.4	1.1	-1.2	2.6	1.2	-1.9	-1.7	-2.0	-1.6	-2.8
Age at First Birth	3.1	4.5	9.1	3.0	-0.3	1.0	2.7	2.8	2.6	2.8	2.4	-0.2	-0.4	-1.3	-1.2	-1.4	-0.6	-2.2	2.7	-0.7	-2.2	-2.6	-3.0	-2.5	-2.7
Number of full sisters	3.1	3.7	8.3	-2.0	0.7	-1.5	-2.6	-2.8	-2.7	-2.5	-2.9	-0.8	-0.9	1.2	1.4	0.5	0.4	1.5	-2.4	0.8	2.5	2.1	1.8	2.1	2.7
Trunk fat mass	3.0	12.7	24.4	3.9	0.8	2.9	4.4	4.7	4.4	4.5	4.0	1.6	3.3	-0.2	-3.2	-0.6	0.1	-1.9	4.5	1.5	-4.9	-4.9	-4.3	-4.4	-4.7
Arm fat percentage (right)	3.0	11.9	26.1	4.0	0.5	1.8	4.5	4.5	4.4	4.5	3.7	0.7	2.2	-0.5	-3.6	-1.6	-0.2	-2.6	4.4	0.6	-5.1	-4.9	-4.1	-4.1	-4.4
Mouth/teeth dental problems: Dentures	3.0	5.1	8.1	-2.8	2.7	-0.1	-2.6	-2.4	-2.5	-2.6	-2.8	-0.1	0.3	2.8	2.0	1.6	2.6	1.7	-2.1	1.6	2.7	2.7	2.8	2.4	2.0
Primary Biliary Cirrhosis	2.9	4.1	7.7	2.2	1.4	2.3	2.7	2.6	2.7	2.7	1.5	-0.3	1.0	-0.7	-1.6	0.1	-0.8	-1.2	2.8	1.8	-2.2	-2.4	-2.6	-2.1	-2.7
Alcohol intake frequency.	2.9	6.8	16.8	2.7	1.7	2.5	3.7	3.5	3.6	3.7	1.8	1.7	2.2	1.2	-0.7	-0.1	1.5	0.4	3.6	2.0	-3.3	-2.8	-2.4	-2.7	-4.1
Pain experienced in last month	2.9	4.9	9.7	2.6	-2.1	-1.8	1.8	1.6	1.8	1.8	1.7	-1.9	-1.9	-3.0	-2.5	-3.1	-3.1	-3.1	1.6	-2.5	-2.0	-1.8	-2.0	-2.1	-1.0
Relative age of first facial hair	2.8	5.7	11.0	2.9	0.3	-0.0	2.7	2.8	2.7	2.8	2.5	-0.8	-0.4	-1.8	-2.9	-2.1	-1.3	-2.7	2.7	-1.1	-3.3	-3.3	-3.1	-3.0	-2.5
Eye problems/disorders: Glaucoma	2.8	3.3	6.8	2.6	-0.4	-0.6	2.2	2.0	2.2	2.2	1.2	-1.5	-1.6	-1.7	-1.1	-2.3	-1.6	-0.8	2.1	-0.5	-2.1	-2.2	-2.6	-2.0	-1.8
Prostate Cancer	2.7	3.8	7.0	2.5	-0.4	0.7	2.0	2.2	2.1	2.2	2.5	-1.6	-0.9	-1.8	-2.3	-1.4	-1.4	-2.6	2.0	-0.8	-1.9	-2.4	-2.6	-1.9	-2.0
Hayfever/allergic rhinitis (self-reported)	2.7	3.5	8.3	1.8	2.2	1.9	2.4	2.4	2.4	2.4	1.4	0.1	1.2	0.2	-2.0	0.0	0.5	-0.5	2.6	1.3	-1.9	-2.0	-2.1	-2.4	-2.9
Seen a psychiatrist for nerves, anxiety, tension or depression	2.7	3.5	7.6	2.6	0.8	1.6	2.5	2.7	2.5	2.7	1.9	-1.0	0.7	-0.7	-1.3	-0.7	-0.6	-0.6	2.6	1.3	-2.0	-2.0	-2.2	-2.0	-2.4
Alzheimer’s Disease (in mother)	2.6	3.0	6.2	2.3	-0.1	-0.1	2.5	2.3	2.5	2.4	0.4	-1.0	-1.9	-0.7	-1.6	-1.5	-0.1	-1.4	2.4	-0.9	-2.1	-1.9	-2.1	-1.7	-2.1
Health satisfaction	2.6	3.3	10.1	-1.0	2.3	3.2	-0.4	-0.3	-0.3	-0.2	-0.8	2.4	2.4	2.8	1.8	3.0	3.0	2.0	-0.3	3.0	0.9	0.6	0.7	0.2	-0.7
Commuting to job workplace: Car/motor vehicle	2.6	3.0	6.4	-1.8	2.3	1.6	-1.4	-1.3	-1.4	-1.3	-1.5	2.0	1.8	2.3	1.3	2.5	2.1	2.3	-1.1	2.2	1.9	1.6	1.6	0.7	0.5
Myopia	2.6	3.7	14.6	-0.8	-2.0	-2.5	-1.6	-1.7	-1.6	-1.7	-1.7	-1.5	-3.8	-2.5	0.2	-1.0	-2.5	-0.7	-1.8	-2.3	1.4	1.5	1.1	2.1	2.7
Crohns Disease (2012)	2.5	4.0	13.3	1.7	1.3	3.7	2.2	2.3	2.2	2.3	2.5	1.7	2.5	0.1	0.9	1.7	0.0	-0.0	2.3	2.8	-1.3	-1.5	-1.6	-1.9	-2.6
Chronotype (morning person)	2.5	5.8	20.0	1.3	1.3	4.0	2.1	2.1	2.1	2.2	2.1	4.5	4.2	1.8	0.1	2.1	1.8	0.2	2.0	2.5	-1.4	-2.0	-1.8	-2.4	-3.3
Heel bone mineral density (BMD) T-score, automated (left)	2.5	5.8	10.2	3.1	-1.5	-0.6	2.5	2.4	2.5	2.7	2.3	-2.2	-2.4	-3.1	-1.4	-2.9	-2.6	-2.4	2.2	-1.6	-2.5	-2.8	-3.2	-2.2	-1.7
Miserableness	2.5	4.3	11.2	2.5	0.4	-0.5	2.4	2.4	2.3	2.5	1.6	-1.8	0.0	-0.9	-3.3	-2.3	-0.9	-2.0	2.5	-0.5	-2.9	-2.7	-2.4	-2.1	-2.0
Reaction Time	2.4	4.6	7.8	-2.6	0.6	-0.2	-2.4	-2.7	-2.5	-2.4	-2.7	1.0	-1.8	1.5	2.6	1.3	2.0	2.5	-2.8	-0.3	2.8	2.6	2.3	2.4	2.0
Taking other prescription medications	2.4	3.7	7.8	2.3	0.8	1.1	2.7	2.7	2.6	2.7	1.1	-0.4	0.2	0.1	-1.2	-1.1	0.5	-0.8	2.8	0.5	-2.4	-2.7	-2.8	-2.1	-2.8
Breastfed as a baby	2.4	3.0	6.0	2.2	1.4	2.0	2.1	2.2	2.1	2.2	1.9	0.0	0.7	-0.7	-1.6	-0.0	-0.2	-1.6	2.2	0.7	-1.2	-1.9	-2.5	-2.2	-2.3
Family relationship satisfaction	2.4	3.0	11.9	0.0	2.2	3.1	0.7	1.0	0.7	0.8	0.9	2.2	2.7	2.3	1.2	2.1	2.5	1.2	0.9	3.5	-0.1	-0.7	-0.8	-0.8	-1.7
Average weekly red wine intake	2.4	3.5	7.0	-2.4	0.2	-0.6	-2.6	-2.2	-2.6	-2.5	-1.5	0.3	0.3	1.0	2.0	1.2	1.0	1.0	-2.3	0.1	2.5	2.4	2.4	2.6	2.3
Headache pain in last month	2.3	3.9	16.0	-0.5	4.0	2.6	0.3	0.6	0.3	0.3	-0.1	1.4	3.6	3.4	0.8	2.3	3.4	2.4	0.9	3.1	0.1	-0.1	0.3	-0.5	-1.4
Whole body fat mass	2.3	9.8	19.7	3.4	0.6	2.5	3.8	4.1	3.8	3.9	3.5	1.5	3.1	0.1	-2.7	-0.5	0.3	-1.7	3.9	1.3	-4.4	-4.4	-3.7	-3.8	-4.1
Pack years of smoking	2.3	3.4	7.5	-2.7	0.0	-0.8	-2.2	-2.3	-2.2	-2.5	-2.3	0.3	-0.4	1.0	0.8	1.6	0.8	0.8	-2.1	0.1	2.3	2.5	2.5	2.6	2.2
Frequency of unenthusiasm / disinterest in last 2 weeks	2.1	2.8	5.8	2.0	-0.1	1.3	2.0	2.1	2.1	2.2	1.9	-0.6	0.6	-1.0	-1.8	-0.5	-1.3	-1.1	2.1	0.5	-2.1	-2.4	-2.2	-1.9	-1.9
Illnesses of father: None of the above (group 1)	2.1	2.6	9.5	-0.9	-2.0	-2.9	-1.5	-1.4	-1.5	-1.6	-0.4	-1.9	-2.1	-1.1	0.3	-2.0	-0.9	-0.6	-1.5	-3.1	1.1	1.2	1.0	1.4	1.9
Arm fat mass (left)	2.1	8.6	15.6	2.7	1.2	3.0	3.4	3.7	3.4	3.5	3.0	2.3	3.9	1.0	-2.1	0.5	1.1	-1.0	3.5	2.0	-3.9	-3.9	-3.1	-3.4	-3.9
Illnesses of father: High blood pressure	2.1	2.6	4.7	2.0	-0.5	2.1	2.1	1.9	2.0	2.2	1.6	1.7	0.1	-1.2	-0.1	0.6	-1.0	-1.0	1.9	0.3	-1.5	-1.8	-2.0	-2.2	-2.2
Intelligence (Savage-Jansen 2018)	2.0	6.3	14.1	-1.5	-3.0	-3.2	-2.8	-2.3	-2.7	-2.8	0.5	-1.5	-3.8	-3.2	1.9	-1.2	-2.4	-1.4	-3.0	-3.8	2.4	1.9	1.2	2.0	3.3
Alzheimer’s Disease (including proxy)	2.0	2.9	6.6	1.8	1.3	2.0	2.6	2.4	2.6	2.5	0.8	-0.6	0.1	0.7	-0.9	0.1	0.9	-0.5	2.6	1.5	-1.8	-1.4	-1.5	-1.4	-2.6
Irritable Bowel Disease (IBD)	2.0	4.7	9.5	2.7	1.2	2.5	3.0	2.9	3.0	3.1	2.1	1.0	1.1	-0.8	-0.2	0.3	-0.9	-1.1	2.9	2.3	-2.3	-2.4	-2.5	-2.0	-2.9
Angina	2.0	2.6	8.5	0.0	2.6	2.5	1.1	1.0	1.1	1.0	-0.2	1.6	1.9	2.6	1.1	1.9	2.9	1.6	1.3	2.5	-0.2	-0.2	-0.2	-0.0	-1.7
Arm fat mass (right)	2.0	8.3	15.6	2.8	0.9	2.7	3.4	3.7	3.4	3.5	3.1	2.1	3.6	0.8	-2.1	0.1	0.9	-1.1	3.5	1.7	-3.9	-4.0	-3.2	-3.4	-3.9
Chest pain or discomfort	2.0	3.0	8.2	0.1	2.7	2.9	1.0	1.2	1.0	1.1	0.1	1.6	2.3	2.3	1.2	2.2	2.6	2.1	1.3	2.7	0.1	-0.3	-0.6	-1.0	-1.9
Commuting to job workplace: Public transport	2.0	2.4	10.9	-0.5	-1.6	-2.7	-0.8	-1.0	-0.9	-1.1	-1.2	-2.6	-3.3	-1.6	-0.1	-1.6	-1.5	-1.0	-1.0	-2.4	0.7	0.9	0.5	1.2	1.6
Heel T-Score	1.9	15.4	28.3	5.3	-1.9	0.0	4.7	4.3	4.7	4.8	3.3	-2.1	-4.2	-5.3	-1.5	-3.9	-4.1	-3.4	4.1	-2.4	-3.7	-4.2	-5.2	-4.4	-3.7
Frequency of tenseness / restlessness in last 2 weeks	1.9	3.0	6.1	2.4	-0.3	1.1	2.1	2.1	2.2	2.4	1.3	-0.4	-0.8	-2.0	-0.9	-0.9	-1.9	-1.1	2.0	-0.2	-2.0	-2.3	-2.5	-1.7	-1.9
Heel bone mineral density (BMD) T-score, automated (right)	1.9	4.4	8.0	2.8	-1.8	-0.4	2.4	2.2	2.4	2.5	1.7	-1.9	-2.5	-2.7	-0.5	-2.4	-2.2	-1.3	1.9	-1.7	-2.1	-2.3	-2.7	-2.0	-1.6
Medication: Simvastatin	1.9	2.8	5.8	-2.2	0.6	-0.5	-1.8	-1.9	-1.9	-1.8	-2.3	0.5	0.7	2.4	1.7	0.9	2.3	2.3	-1.7	0.7	1.6	1.4	1.6	1.8	1.5
Trunk fat-free mass	1.9	10.8	32.4	-2.9	2.5	4.0	-1.9	-1.2	-1.8	-1.8	-1.2	5.3	5.7	4.8	3.7	5.3	4.2	4.3	-1.3	4.2	2.2	1.4	1.9	1.1	0.1
Pulse wave Arterial Stiffness index	1.9	2.2	9.8	-0.5	2.5	1.8	0.1	0.3	0.1	0.0	0.3	1.8	3.1	2.3	-0.0	2.0	2.2	1.3	0.6	2.9	0.2	0.1	0.2	-0.4	-0.9
Trunk predicted mass	1.9	10.7	32.5	-2.8	2.5	4.0	-1.9	-1.1	-1.8	-1.8	-1.2	5.3	5.7	4.8	3.7	5.2	4.3	4.4	-1.3	4.2	2.2	1.4	1.9	1.1	0.0
Wheeze or whistling in the chest in last year	1.9	3.4	7.8	2.1	0.5	1.4	2.4	2.2	2.4	2.4	2.1	-0.3	0.6	-0.7	-1.4	-0.5	-0.4	-1.5	2.3	0.5	-1.9	-2.3	-2.5	-2.8	-2.6
Medication: Allopurinol	1.9	2.6	6.0	1.5	1.3	2.2	1.9	1.7	1.8	1.9	1.9	1.3	1.2	-0.0	-0.4	0.6	0.3	-0.7	1.8	1.2	-1.3	-1.9	-2.1	-2.5	-2.4
Verbal and Numeric Reasoning (VNR)	1.8	4.3	8.1	-1.6	-2.5	-1.7	-2.5	-2.3	-2.4	-2.5	0.1	-0.0	-2.7	-2.4	2.7	0.1	-1.8	-0.6	-2.8	-2.4	2.5	1.9	1.1	1.8	2.6
Pack years adult smoking proportion	1.8	2.8	6.2	-2.5	-0.0	-0.3	-2.0	-2.1	-2.0	-2.2	-1.9	0.4	0.0	0.8	0.9	1.8	0.4	0.7	-1.9	0.4	2.2	2.3	2.3	2.4	2.1
Angina (self-reported)	1.8	2.3	8.5	-0.2	2.5	2.2	0.9	0.8	0.9	0.8	-0.5	1.6	1.6	2.6	1.1	1.9	2.9	1.7	1.0	2.5	-0.0	0.0	0.0	0.2	-1.4
Arm predicted mass (right)	1.8	9.0	31.8	-2.7	2.0	3.4	-2.0	-1.2	-1.9	-1.8	-1.0	5.0	5.6	4.5	3.2	4.7	3.8	3.8	-1.3	3.8	1.8	1.1	1.7	0.9	0.3
Had major operations	1.8	2.1	5.6	-1.5	1.7	0.5	-1.3	-1.2	-1.3	-1.2	-2.2	0.6	-0.0	2.1	1.3	1.6	2.4	1.9	-1.0	1.2	1.8	1.5	1.3	1.4	0.7
Vitamin and mineral supplements	1.7	2.3	9.7	-1.0	-1.4	-3.1	-1.7	-1.6	-1.6	-1.7	-1.4	-1.6	-1.9	-0.5	-0.3	-1.6	-0.8	-0.0	-1.6	-1.9	0.9	1.0	1.1	1.1	2.2
Serious illness, injury or assault to yourself	1.7	2.0	7.7	1.0	1.2	2.8	1.4	1.3	1.5	1.5	1.2	2.3	1.3	0.2	0.4	1.5	0.8	0.0	1.3	1.1	-0.8	-1.4	-1.5	-1.7	-2.0
Comparative body size at age 10	1.7	4.6	12.4	-2.3	-2.3	-3.5	-2.7	-2.5	-2.7	-2.9	-2.2	-1.1	-0.7	1.1	0.7	-1.2	0.2	1.5	-2.5	-2.1	1.3	1.8	2.4	2.6	3.1
Pulse wave peak to peak time	1.7	2.0	7.8	0.7	-2.5	-1.6	0.1	-0.1	0.1	0.2	0.1	-1.8	-2.8	-2.2	0.0	-2.0	-2.2	-1.2	-0.4	-2.7	-0.4	-0.3	-0.4	0.1	0.7
Forced expiratory volume in 1-second (FEV1), predicted	1.7	3.4	12.3	1.2	1.3	3.5	1.7	2.0	1.8	1.8	2.2	2.5	3.1	-0.2	0.1	2.1	-0.0	0.3	1.8	1.8	-1.3	-1.5	-1.4	-2.2	-2.2
Number of treatments/medications taken	1.6	2.9	6.4	1.2	2.4	1.9	1.9	1.9	1.8	2.0	0.8	0.7	2.0	2.0	0.0	0.4	2.3	0.5	2.2	2.5	-1.5	-1.5	-1.4	-0.9	-2.3
Supplements: Zinc	1.6	1.7	7.3	1.3	-0.8	-0.1	1.1	1.2	1.2	1.2	1.3	-0.8	-0.0	-1.4	-2.7	-1.1	-1.2	-2.5	1.2	-1.0	-1.4	-1.1	-1.0	-1.3	-0.9
Medication: Co-codamol	1.6	1.8	3.4	-1.3	-0.6	-1.2	-1.9	-1.8	-1.8	-1.7	-1.8	-0.9	-1.4	0.1	1.7	-0.5	0.4	1.3	-1.8	-1.0	1.6	1.0	0.9	1.3	1.6
Diverticular disease/diverticulitis (self-reported)	1.6	1.9	3.7	-1.6	-0.4	-1.0	-1.9	-1.8	-1.8	-1.9	-1.3	0.5	-0.3	0.2	1.9	0.5	-0.1	1.3	-1.9	-0.2	1.6	1.7	1.7	1.4	1.8
Medication: Cholesterol lowering	1.6	2.4	7.8	-1.6	0.9	1.0	-0.9	-1.1	-1.0	-1.0	-1.6	2.0	2.0	2.8	1.8	1.8	2.8	2.1	-0.9	1.5	1.2	1.1	1.2	1.2	0.3
Lung cancer (father)	1.6	1.9	3.7	-1.6	1.3	-0.4	-1.6	-1.6	-1.6	-1.6	-1.9	0.2	-0.7	1.5	1.0	0.8	1.8	1.2	-1.4	0.1	1.7	1.7	1.7	1.5	1.2
Arm fat-free mass (right)	1.6	8.2	31.9	-2.4	2.0	3.5	-1.6	-0.9	-1.6	-1.5	-0.7	5.1	5.6	4.2	3.0	4.5	3.6	3.5	-1.0	3.7	1.5	0.7	1.4	0.6	-0.1
Illnesses of siblings: Diabetes	1.6	2.0	8.9	-1.2	1.9	0.8	-0.6	-0.7	-0.6	-0.6	-1.3	1.3	1.6	2.7	1.0	1.3	3.0	2.1	-0.5	1.4	0.6	1.1	1.7	1.1	0.1
Body Mass Index (BMI) (2010)	1.5	2.0	5.0	1.1	1.2	1.4	1.6	1.8	1.6	1.6	1.2	1.4	2.2	0.5	-0.7	0.2	0.2	0.3	1.9	1.7	-1.5	-1.6	-1.3	-1.7	-2.0
Fasting Glucose	1.5	1.9	4.4	1.4	1.5	2.0	1.8	1.7	1.8	1.8	0.8	0.8	1.3	0.7	-0.9	0.6	0.9	-0.2	2.0	1.2	-1.0	-0.9	-0.9	-1.3	-2.1
Multivitamins +/- minerals	1.5	1.9	7.4	1.0	1.2	2.7	1.5	1.3	1.4	1.6	1.5	1.3	2.2	0.6	-0.1	1.2	0.6	-0.4	1.4	2.0	-1.0	-1.0	-0.9	-1.1	-1.9
Chronic bronchitis/emphysema (father)	1.5	1.8	6.6	-1.2	2.5	0.9	-1.0	-0.9	-0.9	-1.0	-1.6	0.7	1.9	1.9	0.4	1.4	1.4	1.7	-0.7	2.6	0.8	0.6	0.9	0.5	0.5
Nervous feelings	1.5	2.8	6.2	2.5	-1.2	-0.2	1.9	1.7	1.9	2.1	1.3	-2.0	-1.9	-1.5	-0.2	-2.3	-1.1	-0.5	1.5	-0.7	-1.6	-2.1	-2.5	-1.5	-1.6
Ever unenthusiastic/disinterested for a whole week	1.5	1.8	6.2	0.3	2.5	2.1	0.9	1.4	1.0	1.0	0.5	0.6	1.6	1.7	-0.4	1.3	2.2	1.2	1.3	2.1	-0.3	-0.5	-0.5	-0.1	-1.6
Average weekly champagne plus white wine intake	1.5	2.1	8.5	-0.7	1.4	2.3	0.2	0.3	0.2	0.0	-0.2	2.9	2.3	1.3	1.9	2.2	1.4	2.2	0.2	2.4	0.5	0.4	0.3	-0.2	-0.9
Leg fat percentage (left)	1.5	5.3	13.7	2.7	-0.2	0.5	2.8	2.8	2.8	2.8	2.4	0.4	1.4	-0.3	-2.8	-1.6	-0.2	-1.9	2.8	0.2	-3.7	-3.5	-2.8	-2.5	-2.6
Arm fat-free mass (left)	1.5	7.6	28.7	-2.2	1.8	3.3	-1.5	-0.8	-1.4	-1.4	-0.8	4.7	5.4	4.2	2.8	4.2	3.6	3.7	-0.9	3.6	1.4	0.7	1.4	0.7	-0.1
Average weekly beer plus cider intake	1.5	2.2	4.8	-1.5	0.4	-1.8	-2.0	-2.1	-2.0	-2.0	-1.8	-1.1	-1.2	0.3	0.0	0.0	0.1	0.0	-1.9	-0.4	1.7	1.8	1.8	1.4	2.2
Arm predicted mass (left)	1.5	7.5	27.5	-2.2	1.9	3.4	-1.4	-0.7	-1.3	-1.3	-0.8	4.6	5.2	4.2	2.9	4.3	3.7	3.5	-0.9	3.6	1.4	0.7	1.3	0.7	-0.1
Schizophrenia (2014)	1.4	3.1	18.4	0.2	1.6	2.5	1.1	1.0	1.0	1.0	0.5	-0.5	1.8	2.9	2.6	2.1	2.2	2.5	1.2	4.3	-0.0	0.2	0.2	-0.1	-1.5
Type 2 Diabetes (T2D) (2018)	1.4	2.7	7.3	1.3	0.8	2.4	2.0	1.9	1.9	2.0	1.4	1.4	2.7	0.7	-1.1	0.9	0.8	-0.6	2.0	1.4	-1.8	-1.8	-1.4	-1.5	-2.2
Hip circumference	1.4	6.0	14.1	2.6	-0.8	1.6	2.9	3.2	2.9	2.9	2.7	1.1	2.5	-0.2	-1.9	-0.7	-0.2	-0.8	2.9	0.4	-3.6	-3.8	-3.1	-3.3	-3.1
Pulse wave reflection index	1.4	1.7	8.3	-0.7	1.2	1.7	-0.3	-0.2	-0.3	-0.3	0.1	2.5	2.9	1.6	1.2	2.2	1.4	1.4	-0.1	1.9	0.7	0.8	0.8	-0.2	-0.4
Leg fat percentage (right)	1.4	5.2	13.9	2.7	-0.3	0.4	2.9	2.8	2.8	2.9	2.4	0.5	1.3	-0.4	-2.7	-1.6	-0.2	-1.8	2.8	0.1	-3.7	-3.4	-2.8	-2.5	-2.7
Age at first live birth	1.4	2.5	5.5	1.8	-1.6	-1.1	1.1	1.5	1.2	1.3	1.9	-1.8	-0.9	-2.2	-1.7	-2.3	-1.8	-2.4	1.2	-1.4	-1.8	-1.7	-1.6	-0.7	-0.5
Medication: Seretide 50 evohaler	1.4	1.6	3.0	1.5	0.2	1.5	1.6	1.4	1.6	1.7	0.7	1.6	0.3	-0.4	-1.0	0.0	-0.3	-1.3	1.4	1.0	-1.4	-1.3	-1.3	-1.6	-1.7
Guilty feelings	1.4	2.0	5.8	2.0	0.4	1.0	1.6	1.7	1.6	1.9	1.4	-0.1	0.6	0.1	-0.3	-0.9	0.2	0.2	1.6	0.9	-1.5	-2.1	-2.2	-2.4	-2.1
Supplements: Fish oil (including cod liver oil)	1.4	1.8	9.1	-0.3	3.0	1.5	0.6	0.4	0.5	0.4	0.0	-0.1	1.9	2.3	-0.3	1.4	1.9	1.1	0.8	2.9	-0.3	0.3	0.7	-0.1	-1.0
Schizophrenia (2018)	1.3	2.7	13.3	0.9	1.4	2.2	1.6	1.4	1.5	1.6	0.6	-1.0	1.1	2.5	2.0	1.2	2.1	2.0	1.6	3.7	-0.6	-0.3	-0.3	-0.4	-1.9
Blood Platelet Count	1.3	15.0	28.9	-4.5	-1.6	-3.9	-5.1	-4.7	-5.2	-5.1	-5.2	-1.2	-2.4	0.2	2.6	0.3	-0.3	2.6	-4.8	-1.9	4.2	4.7	5.0	4.7	5.4
Impedance of leg (right)	1.3	6.4	13.1	3.6	0.5	1.3	3.6	3.2	3.6	3.6	2.5	-0.7	-1.5	-2.9	-1.8	-1.2	-2.4	-1.7	3.3	0.4	-2.5	-2.1	-2.8	-2.7	-3.0
Qualifications: CSEs or equivalent	1.3	1.7	5.0	1.6	0.5	0.6	1.5	1.2	1.4	1.5	0.8	-0.0	1.1	-0.4	-2.1	-0.6	-0.7	-1.1	1.5	-0.1	-1.5	-1.6	-1.6	-2.2	-1.6
Impedance of leg (left)	1.3	6.4	12.6	3.5	0.5	1.4	3.5	3.2	3.5	3.5	2.5	-0.9	-1.2	-2.7	-2.0	-1.3	-2.4	-1.7	3.4	0.7	-2.5	-2.2	-2.9	-2.9	-2.9
Qualifications: A levels/AS levels or equivalent	1.3	2.8	11.3	0.7	-2.9	-2.1	-0.2	-0.1	-0.2	-0.1	0.7	-1.3	-3.4	-3.2	-0.0	-2.0	-3.0	-1.2	-0.4	-2.8	-0.0	-0.1	-0.6	0.6	1.1
Length of working week for main job	1.3	1.5	7.0	-0.8	1.4	1.9	-0.7	-0.5	-0.7	-0.4	-0.5	2.6	1.9	1.5	0.6	2.1	1.8	0.2	-0.5	1.2	1.1	0.7	0.7	0.6	-0.1
Pain type(s) experienced in last month: Hip pain	1.3	1.6	3.7	-1.6	0.5	0.1	-1.2	-1.1	-1.2	-1.3	-1.8	0.2	-0.3	1.2	1.9	1.2	1.4	1.6	-1.1	0.5	1.5	1.4	1.3	1.8	1.0
Medication: Bendroflumethiazide	1.3	2.0	6.6	1.3	-0.6	-1.8	1.3	1.0	1.2	1.2	0.8	-1.9	-1.8	-0.6	-1.8	-2.6	-0.3	-2.3	1.1	-1.8	-1.7	-1.3	-1.2	-0.3	-0.6
Ever smoked	1.3	2.3	11.6	0.7	-1.6	-1.9	-0.0	-0.1	0.0	0.0	-0.0	-2.4	-3.4	-2.6	-1.0	-1.8	-2.0	-1.5	-0.3	-2.6	-0.4	-0.8	-1.2	-0.2	0.5
Hand grip strength (left)	1.2	3.2	8.3	-2.0	1.5	0.5	-2.2	-1.7	-2.2	-2.0	-0.9	0.5	2.9	2.3	1.1	1.9	1.2	1.8	-1.6	2.3	2.0	1.6	1.7	1.7	1.7
Sensitivity / hurt feelings	1.2	2.0	4.6	2.0	-0.9	1.5	1.9	1.8	1.9	2.1	1.7	0.1	0.1	-1.2	-0.2	-0.2	-0.7	-0.4	1.6	-0.2	-1.4	-1.5	-1.8	-1.7	-2.0
Fluid intelligence score	1.2	2.4	7.4	-1.4	-1.8	-1.0	-1.9	-1.7	-1.8	-1.9	0.3	-0.1	-1.7	-1.6	2.7	0.4	-1.3	0.3	-2.2	-1.2	1.9	1.4	0.8	1.6	1.9
Weight	1.2	6.1	19.6	1.8	1.2	3.3	2.3	2.9	2.4	2.5	2.4	2.8	4.4	1.5	-1.1	1.2	1.5	-0.0	2.6	2.3	-2.7	-3.1	-2.4	-2.7	-3.2
Prospective memory result	1.2	1.5	3.7	1.5	0.0	0.4	1.4	1.3	1.4	1.5	-0.1	0.8	-0.1	-0.3	-1.9	-0.8	-0.2	-1.9	1.4	-0.7	-1.5	-1.6	-1.4	-1.7	-1.6
Illnesses of mother	1.2	1.5	3.3	-0.9	-1.4	-0.9	-1.4	-1.5	-1.4	-1.4	-0.9	-0.1	-1.5	-1.7	0.5	0.1	-1.8	-0.2	-1.7	-0.9	1.4	1.4	1.1	1.0	1.6
Leg fat mass (right)	1.2	4.5	9.8	2.1	0.1	1.6	2.4	2.7	2.5	2.5	2.3	1.6	2.6	0.4	-2.0	-0.2	0.5	-1.1	2.5	0.9	-3.1	-3.1	-2.4	-2.4	-2.7
Whole body fat-free mass	1.2	7.0	31.2	-1.7	2.0	3.8	-0.9	-0.2	-0.9	-0.8	-0.1	4.7	5.6	3.9	2.5	4.2	3.5	3.2	-0.4	3.5	1.0	0.2	0.8	0.0	-0.7
Loneliness, isolation	1.2	1.7	4.1	1.3	1.1	1.1	1.5	1.5	1.5	1.6	1.1	0.8	1.0	-0.1	-1.1	-0.4	0.3	-0.6	1.5	0.1	-1.4	-1.8	-1.8	-2.0	-1.9
Qualifications: nursing, teaching	1.2	1.9	4.3	1.5	0.0	0.4	1.5	1.7	1.5	1.5	2.1	-0.5	0.3	-1.5	-1.6	-0.7	-1.2	-1.5	1.5	-0.3	-1.9	-2.0	-1.9	-1.1	-1.3
Eye problems/disorders: Cataract	1.2	1.4	3.1	1.3	-1.1	-0.7	1.2	1.4	1.1	1.3	1.3	-1.2	0.0	-0.6	-1.3	-1.7	-0.0	-0.9	1.2	-1.6	-1.8	-1.6	-1.4	-0.4	-0.7
Whole body water mass	1.2	7.0	29.8	-1.9	1.9	3.7	-1.1	-0.3	-1.0	-0.9	-0.3	4.7	5.5	4.0	2.6	4.2	3.6	3.2	-0.5	3.5	1.1	0.3	0.9	0.2	-0.6
Ever taken oral contraceptive pill	1.2	1.3	2.1	-1.1	-1.1	-1.1	-1.4	-1.4	-1.3	-1.4	-1.3	-0.1	-1.2	-0.8	0.3	0.0	-0.9	-0.6	-1.5	-1.2	1.5	1.4	1.1	0.9	1.5
Alcohol drinker status: Never	1.2	1.5	3.3	1.5	0.4	0.0	1.5	1.7	1.5	1.6	1.1	-0.1	0.7	0.0	-1.2	-1.1	0.2	-0.7	1.8	0.3	-1.8	-1.5	-1.2	-1.4	-1.6
Unable to work because of sickness or disability	1.2	1.6	3.1	-1.3	0.9	-0.5	-1.4	-1.4	-1.4	-1.4	-1.8	-0.3	0.1	1.4	1.2	0.5	1.0	1.7	-1.2	0.8	1.6	1.7	1.7	1.2	1.2
Lung FVC	1.1	5.5	10.3	-2.1	-1.4	-3.2	-2.5	-2.3	-2.5	-2.7	-1.9	-2.5	-2.9	-0.0	2.6	-0.9	0.2	1.1	-2.4	-3.0	2.5	2.8	2.5	3.0	2.9
Relative age voice broke	1.1	1.7	3.1	1.6	0.8	1.1	1.6	1.7	1.6	1.6	1.0	0.0	0.6	-0.7	-1.6	-0.2	-0.8	-1.4	1.8	0.6	-1.5	-1.6	-1.6	-1.5	-1.6
Waist circumference	1.1	3.9	8.2	1.6	1.0	2.1	2.1	2.4	2.1	2.2	1.9	1.8	2.7	1.2	-1.3	0.4	1.4	-0.7	2.2	1.7	-2.5	-2.9	-2.3	-2.2	-2.6
Illnesses of siblings	1.1	1.5	8.8	0.6	-2.0	-1.1	-0.4	-0.3	-0.3	-0.3	0.8	-0.3	-0.8	-2.7	-1.1	-1.1	-3.0	-1.9	-0.5	-1.4	-0.1	-0.2	-0.3	-0.8	0.7
Depression (self-reported)	1.1	1.4	3.0	1.7	0.0	0.9	1.4	1.6	1.4	1.6	1.7	-0.1	0.6	-0.4	0.2	-0.6	-0.5	-0.4	1.5	0.8	-1.2	-1.5	-1.6	-1.3	-1.5
Hair/balding pattern: Pattern 4	1.1	2.7	10.4	-0.5	-2.6	-2.4	-1.4	-1.8	-1.5	-1.3	-1.2	-1.0	-3.0	-1.3	0.2	-1.3	-1.1	-0.6	-1.7	-3.2	1.3	1.0	0.6	1.1	1.9
Medication: Amlodipine	1.1	1.6	3.0	-1.3	-0.5	-1.5	-1.7	-1.5	-1.7	-1.6	-1.5	-1.0	-1.0	0.8	0.5	-0.2	0.6	0.7	-1.5	-0.8	1.3	1.4	1.6	1.3	1.6
Medication for pain relief, constipation, heartburn	1.1	1.9	7.6	-0.8	-1.5	-1.9	-1.6	-1.6	-1.5	-1.5	-0.6	-0.5	-2.1	-1.2	-0.7	-0.9	-0.8	-1.0	-1.9	-2.8	1.2	0.9	0.7	0.6	1.6
Illnesses of father: Heart disease	1.1	1.6	5.8	-0.7	0.7	2.0	-0.0	-0.1	-0.1	-0.1	-0.6	2.4	1.6	1.7	1.4	2.2	1.8	1.7	-0.1	1.8	0.7	0.7	0.6	0.4	-0.6
Ever had stillbirth, spontaneous miscarriage or termination	1.1	1.2	3.9	0.8	-2.0	-0.7	0.5	0.5	0.4	0.6	1.1	-0.2	-0.9	-1.8	-0.9	-1.2	-1.5	-1.7	0.1	-1.9	-0.9	-1.0	-1.0	-0.5	0.1
Financial situation satisfaction	1.1	1.4	5.3	0.1	2.3	2.3	0.5	0.7	0.5	0.6	0.3	1.6	1.9	1.0	0.5	1.6	1.3	0.4	0.8	2.1	-0.0	-0.2	-0.2	-0.9	-1.1
Medication: Omeprazole (e.g. Zanprol)	1.1	1.4	3.3	1.3	0.7	0.9	1.5	1.5	1.5	1.5	1.4	-0.2	-0.3	-0.9	0.3	-0.4	-0.6	0.0	1.5	0.8	-1.0	-1.5	-1.8	-1.5	-1.6
Leg fat mass (left)	1.1	4.3	9.7	2.0	0.0	1.6	2.4	2.6	2.4	2.4	2.2	1.5	2.6	0.5	-2.0	-0.2	0.5	-1.1	2.4	0.9	-3.1	-3.1	-2.4	-2.4	-2.6
Rheumatoid Arthritis	1.0	1.3	4.1	-1.2	-0.4	-0.4	-1.4	-1.7	-1.5	-1.3	-2.0	0.5	-1.0	0.1	1.3	0.7	0.2	0.6	-1.7	-0.6	1.4	1.0	0.9	1.3	1.3
Height	1.0	19.2	82.6	-0.1	5.7	9.1	1.8	2.8	1.9	1.9	2.6	6.5	7.4	3.8	2.6	7.2	4.3	3.5	2.6	7.2	0.5	-0.7	-1.1	-2.1	-4.3
Frequency of depressed mood in last 2 weeks	1.0	1.4	2.7	1.4	0.7	1.5	1.4	1.5	1.4	1.5	0.8	0.1	0.8	-0.3	-0.5	0.2	-0.4	-0.3	1.5	1.2	-1.0	-1.4	-1.6	-1.5	-1.6
Hand grip strength (right)	1.0	2.7	7.8	-1.9	1.2	1.2	-1.8	-1.3	-1.7	-1.7	-0.4	1.1	2.8	2.1	0.9	2.4	1.0	1.4	-1.3	2.6	1.8	1.5	1.7	1.5	1.2
Ever highly irritable/argumentative for 2 days	1.0	1.2	5.0	-0.2	2.2	1.7	0.5	0.9	0.6	0.5	0.1	0.8	1.6	1.4	0.4	1.2	1.5	1.5	0.9	1.8	-0.2	-0.3	-0.1	-0.1	-0.9
Exposure to tobacco smoke outside home	1.0	1.3	2.7	-1.0	0.3	-0.8	-1.6	-1.6	-1.6	-1.4	-1.5	0.7	-1.2	-0.3	1.2	0.3	-0.1	0.4	-1.6	-0.1	1.6	1.4	1.1	0.9	1.4
Migraine (self-reported)	1.0	1.2	3.5	1.1	1.6	0.9	0.9	1.3	0.9	1.0	1.1	-1.1	1.9	0.6	-1.6	-0.1	0.4	0.1	1.4	1.3	-0.8	-1.0	-0.9	-1.0	-1.2
Overall health rating	1.0	2.1	5.0	0.6	1.9	2.2	1.2	1.1	1.2	1.3	0.1	2.0	1.7	1.8	0.3	1.2	1.9	1.3	1.1	2.0	-1.0	-1.2	-1.0	-1.4	-1.9
High cholesterol (Self-reported)	1.0	1.8	3.6	-1.9	-0.0	-0.1	-1.6	-1.8	-1.7	-1.5	-1.6	-0.0	0.4	1.8	0.7	1.1	1.6	1.0	-1.6	0.8	1.5	1.2	1.4	1.6	1.3
Basal metabolic rate	1.0	5.7	29.8	-0.8	1.8	3.9	0.1	0.7	0.1	0.2	0.7	4.4	5.5	3.4	1.5	3.6	3.0	2.4	0.5	3.2	-0.1	-0.7	-0.1	-0.8	-1.5
Commuting to job workplace: Cycle	1.0	1.2	3.4	1.2	-1.0	-1.0	0.8	0.9	0.8	0.8	0.5	-0.8	-1.0	-1.3	-1.3	-1.8	-1.2	-1.0	0.9	-1.4	-1.3	-1.3	-1.1	-0.8	-0.3
Bipolar Disorder or Schizophrenia	0.9	2.3	9.5	0.7	0.4	1.8	1.4	1.4	1.3	1.3	0.4	-0.8	1.4	2.1	2.7	1.1	1.4	2.6	1.5	3.1	-0.5	-0.1	-0.1	-0.3	-1.5
Lung FEV1/FVC ratio	0.9	4.5	11.1	2.5	-0.6	0.5	2.6	2.9	2.6	2.8	2.8	-0.8	1.5	0.5	-2.3	-1.9	0.3	-1.3	2.8	0.0	-3.3	-2.9	-2.2	-1.5	-2.4
Standing height	0.9	8.5	32.0	1.7	2.7	5.7	2.6	3.3	2.7	2.7	2.9	3.2	4.3	1.0	0.5	3.2	1.3	1.5	3.1	3.8	-1.2	-2.0	-2.2	-2.9	-3.9
Gout (self-reported)	0.9	1.2	3.0	1.3	0.7	0.8	1.4	1.2	1.4	1.4	1.3	-0.1	0.8	-0.0	-0.1	-0.4	-0.1	-0.5	1.3	0.6	-1.2	-1.4	-1.4	-1.7	-1.5
Birth weight	0.9	2.0	7.1	-1.5	1.9	-0.4	-1.3	-0.9	-1.2	-1.3	-1.3	-0.2	1.7	2.3	1.5	0.4	2.0	2.7	-0.8	1.5	0.9	0.9	1.2	1.5	1.0
Shortness of breath walking on level ground	0.9	1.1	3.8	0.5	2.0	1.5	0.9	0.8	0.8	0.9	-0.6	1.2	0.5	1.5	0.1	1.0	1.8	0.8	1.0	1.6	-0.3	-0.3	-0.4	-0.8	-1.4
Qualifications: College or University degree	0.9	2.9	14.0	0.9	-2.3	-1.6	-0.1	0.2	-0.0	0.1	1.7	-2.3	-2.5	-3.7	-0.5	-1.8	-3.2	-2.2	-0.2	-2.5	-0.3	-0.7	-1.2	0.0	0.8
Long-standing illness, disability or infirmity	0.9	1.3	4.0	-0.1	1.2	2.0	0.4	0.4	0.4	0.5	0.1	1.5	1.7	1.8	1.4	1.5	1.8	1.7	0.5	1.8	0.1	-0.3	-0.3	-0.4	-1.0
Mineral and other dietary supplements	0.9	1.2	3.2	1.1	-1.6	-1.1	0.4	0.6	0.4	0.5	0.7	0.1	-1.0	-1.7	-0.6	-1.8	-1.7	-1.4	0.4	-1.7	-0.9	-1.4	-1.5	-1.0	-0.1
Heart attack/myocardial infarction (self-reported)	0.9	1.2	3.9	-0.2	1.6	1.5	0.5	0.4	0.5	0.4	-0.4	1.6	1.1	1.3	1.7	1.5	1.3	1.5	0.6	2.0	-0.0	-0.1	-0.2	0.3	-0.7
Age when periods started (menarche)	0.8	2.0	9.7	-0.3	-1.4	-2.5	-1.1	-1.1	-1.0	-1.1	-0.7	-2.5	-3.1	-1.2	-0.0	-1.7	-1.4	-0.4	-1.2	-1.1	0.7	0.9	0.8	0.9	1.7
Leg predicted mass (left)	0.8	4.0	21.9	0.4	1.2	3.3	1.0	1.6	1.1	1.2	1.8	3.2	4.7	2.0	0.2	2.2	2.0	0.8	1.4	2.1	-1.2	-1.8	-1.2	-1.8	-2.2
Number of incorrect matches in round	0.8	1.3	2.7	1.3	-0.2	0.4	1.5	1.4	1.5	1.5	-0.1	0.6	1.0	0.9	-1.1	-1.1	1.0	0.4	1.5	-0.3	-1.6	-1.3	-1.0	-1.3	-1.6
Past tobacco smoking	0.8	1.5	7.5	-0.9	1.5	0.9	-0.5	-0.3	-0.5	-0.5	-0.2	1.8	2.7	2.0	0.7	1.3	1.4	1.0	-0.1	1.8	0.8	1.1	1.4	0.5	0.2
Mouth/teeth dental problems	0.8	1.2	4.5	1.0	-1.1	1.0	1.4	1.2	1.4	1.2	2.1	0.3	0.9	-1.1	-0.7	0.5	-1.3	-1.1	1.1	0.1	-1.1	-0.8	-0.8	-0.8	-1.1
Medication: Lansoprazole	0.8	0.9	4.0	0.4	1.1	1.4	0.8	0.9	0.8	0.8	0.0	0.4	1.4	1.2	0.9	0.7	1.2	1.0	0.9	2.0	-0.4	-0.6	-0.7	-0.1	-1.0
Peak expiratory flow (PEF)	0.8	1.9	4.1	1.6	0.7	1.6	1.7	2.0	1.7	1.7	2.0	0.3	1.8	-0.1	-0.6	0.1	-0.3	-1.0	2.0	0.7	-1.5	-1.4	-1.2	-1.2	-1.9
Suffer from ‘nerves’	0.8	1.3	6.0	1.5	-0.6	-0.5	1.1	1.1	1.2	1.4	1.0	-2.4	-0.5	-0.2	-1.0	-1.7	-0.2	0.5	1.0	-0.4	-1.3	-1.4	-1.4	-1.2	-0.9
Smoking status: Previous	0.8	1.1	3.1	1.3	-0.6	0.2	1.1	1.1	1.2	1.2	0.5	-0.8	-1.2	-1.2	-0.9	-0.8	-0.5	-0.2	0.8	-1.0	-1.3	-1.6	-1.8	-1.2	-1.2
Medication: Aspirin	0.8	1.1	3.1	-1.2	1.1	-0.2	-0.7	-0.9	-0.8	-0.8	-1.2	-0.1	0.1	1.8	1.2	0.7	1.8	1.1	-0.7	1.1	0.9	1.1	1.1	1.6	0.8
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.8	1.7	4.7	1.5	-1.0	-1.5	1.1	1.3	1.2	1.0	1.7	-1.9	-0.7	-1.5	-0.9	-2.2	-1.4	-1.2	1.1	-1.9	-1.4	-0.8	-0.7	-0.6	-0.5
Risk taking	0.8	1.1	6.7	0.4	-1.2	-1.1	0.0	0.1	0.1	0.1	0.5	-1.2	-1.3	-1.6	-1.9	-1.1	-1.4	-2.6	-0.0	-1.6	-0.2	-0.0	-0.2	0.1	0.4
Ever had prostate specific antigen (PSA) test	0.8	0.9	2.0	-1.2	0.4	0.7	-0.9	-0.8	-0.9	-0.9	-0.8	1.2	0.8	1.1	0.5	1.3	1.0	0.8	-0.8	1.4	0.8	0.8	0.9	1.1	0.7
Age started oral contraceptive pill	0.8	1.0	2.8	1.3	-1.1	-0.5	1.1	1.1	1.1	1.2	1.7	-0.2	-0.4	-0.3	-1.0	-1.4	0.1	-1.7	0.9	-1.1	-1.2	-0.9	-0.8	-0.7	-0.8
Cholesterol lowering medication	0.8	1.2	4.3	-1.2	1.1	0.8	-0.7	-0.8	-0.8	-0.7	-0.6	-0.4	1.3	2.1	0.5	1.2	2.0	1.6	-0.7	1.5	0.9	0.7	0.8	1.1	0.4
Mean Putamen Volume	0.7	0.9	2.4	1.0	-0.6	0.4	1.0	0.8	1.0	0.9	0.6	0.5	-0.3	-1.1	-1.0	0.1	-1.1	-1.6	0.9	-0.5	-1.3	-0.9	-0.6	-1.5	-0.8
BMI	0.7	4.3	16.6	1.3	1.2	2.5	1.7	2.1	1.8	1.8	1.4	3.8	4.1	1.3	-1.3	1.2	1.1	-0.4	1.9	1.8	-2.6	-2.6	-1.6	-2.0	-2.3
Cardiovascular Disease	0.7	2.2	4.7	1.5	0.0	0.6	1.9	1.9	1.9	1.9	1.3	-0.7	1.0	-0.1	-2.0	-0.5	-0.4	-1.3	2.0	1.1	-2.2	-1.9	-1.5	-1.7	-1.7
Hearing difficulty/problems: Yes	0.7	1.1	2.9	-1.3	0.4	-0.0	-1.5	-1.4	-1.5	-1.4	-0.8	0.1	-0.5	0.5	0.5	1.0	0.9	0.2	-1.5	-0.1	1.7	1.2	1.0	1.2	1.2
Leg fat-free mass (left)	0.7	3.8	21.5	0.4	1.2	3.2	1.0	1.5	1.0	1.1	1.7	3.2	4.6	2.1	0.2	2.2	2.0	0.9	1.3	2.1	-1.2	-1.7	-1.1	-1.7	-2.1
Townsend deprivation index at recruitment	0.7	1.0	3.7	0.3	-1.8	-0.4	-0.1	-0.1	-0.1	-0.0	1.3	-1.5	-1.5	-1.4	-0.2	-0.8	-1.3	-1.8	-0.3	-1.9	-0.2	-0.5	-0.4	0.2	0.5
Supplements: Glucosamine	0.7	0.9	2.2	-1.1	-0.2	-0.8	-1.1	-1.2	-1.1	-1.1	-0.3	-0.2	-1.2	-0.0	0.4	0.3	0.6	-0.3	-1.3	-1.3	1.1	1.2	1.1	1.5	1.3
Sitting height	0.7	4.7	18.5	-0.9	2.2	4.3	-0.3	0.4	-0.2	-0.3	1.2	3.7	4.3	1.5	2.0	4.2	1.3	2.7	0.2	2.9	1.1	0.6	0.6	-0.4	-1.1
Had other major operations	0.7	0.8	3.2	0.4	-1.6	-0.7	0.0	0.0	0.1	0.2	0.4	-0.8	-1.1	-1.6	-1.2	-1.0	-0.9	-1.8	-0.2	-1.6	-0.4	-0.5	-0.6	0.0	0.2
Diabetes (self-reported)	0.7	1.0	4.4	0.3	0.8	1.9	0.8	0.8	0.8	0.9	0.1	1.4	2.1	1.2	-0.4	1.0	1.4	0.0	0.9	1.0	-0.6	-0.8	-0.7	-0.5	-1.2
Alcohol intake versus 10 years previously	0.7	1.0	4.2	0.1	2.0	1.4	0.7	0.4	0.6	0.6	-0.2	1.2	1.4	1.3	-0.9	0.9	1.4	0.7	0.6	1.3	-0.7	-0.7	-0.4	-0.9	-1.2
Forced expiratory volume in 1-second (FEV1)	0.7	2.5	6.2	1.8	0.7	1.9	2.0	2.5	2.1	2.1	2.4	0.4	1.6	-0.3	0.3	0.2	-0.1	-0.0	2.3	0.4	-1.6	-1.3	-1.4	-1.4	-2.3
Noisy workplace	0.7	0.8	5.4	-0.6	1.7	0.0	-0.0	-0.1	0.0	-0.2	-1.6	0.3	0.8	2.3	-0.8	0.2	2.1	0.6	0.2	0.7	-0.0	0.1	0.4	0.4	-0.2
Forced expiratory volume in 1-second (FEV1), Best measure	0.7	2.3	5.8	1.6	0.7	2.1	2.0	2.4	2.1	2.0	2.4	0.3	1.8	-0.3	0.3	0.6	-0.2	0.2	2.2	0.5	-1.5	-1.1	-1.0	-1.3	-2.2
Neck or shoulder pain in last month	0.7	0.9	3.6	-0.3	1.4	1.7	0.0	0.1	0.0	0.0	0.2	0.6	1.5	1.3	1.2	1.3	1.4	1.5	0.2	1.9	0.3	0.1	0.1	0.1	-0.4
Heart disease (mother)	0.7	0.9	3.1	0.3	1.2	0.8	0.9	0.9	0.9	0.9	0.2	0.9	1.8	1.7	-0.0	0.3	1.7	0.2	1.1	0.9	-0.7	-0.7	-0.7	-0.5	-1.2
Comparative height size at age 10	0.7	4.0	14.1	-1.3	2.3	3.3	-0.7	-0.3	-0.7	-0.5	-0.8	3.6	3.3	2.1	1.5	3.8	2.4	2.8	-0.4	2.5	1.4	1.1	1.2	0.4	-0.3
Medication: Aspirin	0.7	0.9	2.9	-1.2	0.5	-0.2	-0.6	-0.8	-0.7	-0.7	-0.9	-0.1	0.1	1.4	1.4	0.7	1.4	1.0	-0.7	0.8	0.8	1.0	1.0	1.7	0.8
Leg fat-free mass (right)	0.7	3.6	22.2	0.1	1.2	3.1	0.7	1.3	0.7	0.8	1.5	3.0	4.7	2.3	0.4	2.3	2.0	1.1	1.1	2.2	-0.9	-1.6	-1.0	-1.6	-1.8
Mouth/teeth dental problems: Mouth ulcers	0.7	1.0	3.1	1.2	-1.7	-0.7	0.7	0.6	0.6	0.8	0.4	-0.8	-1.5	-1.4	-0.3	-1.8	-1.2	-1.0	0.5	-1.5	-0.8	-0.8	-1.0	-0.7	-0.4
Leg predicted mass (right)	0.7	3.6	22.4	0.1	1.2	3.2	0.7	1.3	0.7	0.8	1.5	3.0	4.7	2.2	0.4	2.3	2.0	1.1	1.1	2.2	-0.9	-1.6	-1.0	-1.6	-1.8
Fractured/broken bones in last 5 years	0.7	0.9	2.3	0.9	0.1	1.2	0.8	0.8	0.8	0.9	1.2	1.1	1.2	-0.9	-1.3	0.5	-1.0	-1.5	0.8	0.4	-0.7	-0.8	-0.9	-1.3	-1.0
Alzheimer’s Disease (in father)	0.6	0.7	3.6	-0.1	1.6	1.3	0.5	0.4	0.5	0.4	0.2	-0.7	0.7	0.9	0.3	1.3	0.7	1.0	0.6	1.9	-0.0	0.2	0.2	0.4	-0.5
Ulcerative Colitis (UC)	0.6	1.1	2.9	1.5	0.9	1.1	1.6	1.5	1.6	1.7	0.5	-0.2	-0.0	-0.3	-0.3	0.1	-0.4	-0.5	1.5	1.5	-1.0	-1.0	-1.2	-0.4	-1.3
Systolic blood pressure, automated reading	0.6	1.7	9.8	-0.8	1.7	0.4	-0.3	-0.4	-0.3	-0.4	-1.1	-0.3	1.9	3.1	-0.4	1.0	2.4	1.8	0.1	2.7	0.4	0.7	1.0	0.5	-0.1
Eye problems/disorders: Diabetes related eye disease	0.6	0.6	3.6	0.6	-0.1	0.4	0.8	1.0	0.8	0.8	0.5	0.4	1.9	0.6	-0.5	-0.2	0.4	0.1	1.0	0.6	-0.9	-0.9	-0.7	-1.0	-1.0
Diabetes (father)	0.6	0.8	3.1	0.1	0.7	1.8	0.7	0.6	0.6	0.7	0.6	1.6	1.1	0.9	-0.1	1.3	1.0	0.1	0.5	1.4	-0.6	-0.6	-0.3	-0.4	-0.9
Average weekly fortified wine intake	0.6	0.7	2.8	0.9	-0.3	0.1	0.7	0.7	0.7	0.7	0.6	0.0	-1.5	-1.7	-1.0	-0.5	-1.1	-1.1	0.6	-1.3	-0.4	-0.6	-1.0	-0.7	-0.5
Stomach or abdominal pain in last month	0.6	0.8	6.5	-0.8	0.5	-0.2	-0.4	-0.6	-0.5	-0.6	-0.8	-0.2	-0.4	0.2	2.6	0.6	-0.3	2.3	-0.4	1.1	0.4	0.2	0.2	0.5	0.6
Alcohol usually taken with meals	0.6	1.0	3.7	0.3	0.6	1.6	0.8	1.1	0.8	0.7	1.6	1.2	1.9	0.0	0.8	1.0	-0.2	0.3	0.9	1.8	-0.5	-0.4	-0.4	-0.5	-1.0
Hair/balding pattern: Pattern 2	0.6	0.8	5.5	-0.6	1.7	1.0	-0.7	-0.5	-0.7	-0.5	-0.3	0.7	1.2	1.3	0.4	1.1	0.8	0.7	-0.5	2.3	0.6	0.1	0.2	0.3	0.2
Heart attack	0.6	0.8	2.5	-0.2	1.1	1.2	0.5	0.4	0.5	0.3	-0.4	1.3	0.8	1.1	1.6	1.2	1.1	1.5	0.6	1.5	-0.1	-0.1	-0.1	0.2	-0.6
Loud music exposure frequency	0.6	0.6	3.4	0.5	-0.9	-0.3	0.3	0.1	0.3	0.2	-0.6	0.6	-1.9	-1.8	0.9	-0.2	-1.6	-0.5	0.0	-0.7	0.1	-0.1	-0.5	-0.5	-0.0
Medication: Paracetamol	0.6	1.1	3.9	0.5	1.1	1.6	0.8	1.1	0.8	0.9	0.4	-0.0	2.0	1.5	0.6	0.6	0.9	0.7	1.2	2.0	-0.7	-0.6	-0.3	-0.4	-1.2
High blood pressure (siblings)	0.6	0.8	4.0	-0.5	0.8	0.1	-0.1	-0.1	-0.1	-0.1	-0.8	0.1	0.4	2.0	1.7	0.3	1.8	2.0	0.0	1.0	0.3	0.4	0.5	0.9	0.1
Eye problems/disorders: None of the above	0.6	0.7	1.8	-0.8	0.3	0.3	-0.8	-1.0	-0.8	-0.9	-1.2	0.4	-0.9	-0.1	0.7	1.1	-0.5	0.3	-0.9	0.8	1.2	1.3	1.2	0.3	0.8
Diabetes diagnosed by doctor	0.6	1.0	3.6	0.6	0.2	1.7	1.0	0.9	1.0	1.2	0.2	1.3	1.9	1.0	-0.6	0.7	1.3	-0.1	1.0	0.6	-0.8	-1.1	-0.9	-0.7	-1.3
Breast cancer (self-reported)	0.6	0.7	3.2	0.4	-0.6	-1.0	-0.1	-0.2	-0.1	0.1	0.4	-1.6	-1.0	-1.0	-1.8	-1.2	-0.4	-1.2	-0.4	-1.5	-0.2	-0.6	-0.8	-0.2	0.3
Osteoporosis (self-reported)	0.6	0.7	3.3	0.5	1.5	0.6	0.5	0.6	0.5	0.6	0.0	0.4	1.7	1.2	0.2	0.2	0.8	0.7	0.8	1.8	-0.5	-0.6	-0.6	-0.2	-0.7
Ever depressed for a whole week	0.6	0.8	3.6	-0.1	1.9	0.8	0.2	0.6	0.3	0.3	-0.8	-0.0	0.6	1.5	-0.1	0.5	1.8	1.6	0.6	1.6	0.1	0.1	0.1	0.3	-0.7
Deep venous thrombosis (DVT) (self-reported)	0.6	0.8	2.6	-0.8	-0.2	-0.1	-1.0	-0.8	-1.0	-0.9	-0.6	0.4	1.2	1.6	1.1	0.2	1.4	1.2	-0.9	0.1	0.9	0.7	0.8	0.8	0.7
Alcohol drinker status: Previous	0.6	0.7	2.3	-0.5	1.0	-0.7	-0.6	-0.6	-0.6	-0.5	-1.5	-0.6	-0.5	1.2	1.5	-0.7	1.3	1.5	-0.4	0.6	0.6	0.4	0.3	0.8	0.5
Depression (Nagel 2018)	0.5	0.8	3.0	0.8	1.1	1.2	1.0	1.0	1.0	1.0	0.3	-0.2	0.9	0.2	-0.4	0.5	-0.3	0.4	1.2	1.7	-0.8	-0.9	-0.8	-0.9	-1.1
Bipolar Disorder (2011)	0.5	0.4	2.0	-0.3	-0.3	0.9	-0.4	-0.2	-0.4	-0.3	-0.1	0.3	1.3	0.2	1.2	1.3	-0.4	0.8	-0.3	1.4	0.4	0.3	0.3	0.1	0.2
HbA1C	0.5	0.6	2.5	-0.1	1.1	0.8	0.5	0.4	0.5	0.5	0.1	0.2	1.3	1.6	0.5	0.4	1.5	0.9	0.4	0.7	-0.5	-0.4	0.0	-0.3	-0.8
Type 2 Diabetes (T2D) (2012)	0.5	0.6	1.6	-0.9	-0.3	-0.7	-1.3	-1.0	-0.9	-1.2	-0.7	-0.0	-0.8	0.1	-0.7	-0.2	0.2	-0.6	-1.0	-0.5	0.7	0.8	1.0	0.5	0.9
Tinnitus: Yes, but not now, but have in the past	0.5	0.5	1.9	-1.0	0.6	-0.4	-0.7	-0.6	-0.7	-0.8	-1.0	-0.1	0.0	1.3	0.0	0.4	1.4	0.5	-0.6	0.3	0.4	0.7	1.0	1.0	0.6
Body mass index (BMI)	0.5	2.1	8.2	1.0	0.2	1.1	1.3	1.5	1.3	1.3	1.2	1.7	2.9	1.3	-1.2	0.1	1.1	-0.6	1.4	0.9	-2.2	-2.3	-1.4	-1.5	-1.6
Father’s age at death	0.5	0.6	2.1	0.0	-1.1	-1.2	-0.6	-0.8	-0.6	-0.5	-0.4	-0.7	-1.4	-1.2	0.5	-0.8	-1.3	-0.1	-0.7	-1.1	0.5	-0.1	-0.4	0.0	1.0
Number of live births	0.5	0.7	5.0	0.8	0.3	-0.8	0.5	0.5	0.5	0.5	0.4	-2.2	-0.4	-0.5	-1.4	-1.3	-0.8	-0.4	0.6	-0.2	-0.6	-0.8	-0.9	-1.0	-0.3
Worry too long after embarrassment	0.5	0.9	2.1	1.3	-0.1	1.3	1.3	1.2	1.3	1.5	0.7	-0.9	-0.4	-0.4	-0.3	-0.0	-0.1	0.2	1.2	0.3	-0.8	-1.1	-1.3	-1.1	-1.4
Medication: Paracetamol	0.5	0.8	3.7	0.3	1.1	1.2	0.6	0.9	0.6	0.7	0.5	-0.3	1.6	1.1	0.8	0.4	0.6	0.8	1.1	1.9	-0.5	-0.3	-0.1	-0.2	-0.8
Diastolic blood pressure, automated reading	0.5	1.6	6.1	0.6	1.6	0.7	0.8	1.2	0.9	0.9	0.6	0.2	2.5	2.3	-0.3	0.2	1.6	1.2	1.4	2.0	-1.2	-1.0	-0.4	-1.1	-1.2
Breast Cancer	0.4	1.1	4.9	0.1	1.8	1.3	0.6	1.0	0.6	0.6	0.4	0.7	1.6	1.9	-0.3	0.6	2.2	-0.7	0.9	1.0	-0.6	-0.8	-0.3	-0.5	-1.2
Lupus	0.4	0.7	2.0	0.8	0.4	0.3	1.1	1.1	1.1	1.2	0.1	-0.7	0.0	0.4	-0.8	-0.5	0.7	-0.5	1.0	-0.1	-1.4	-1.2	-1.0	-0.2	-0.9
Ever used hormone-replacement therapy (HRT)	0.4	0.5	2.2	-0.3	1.5	0.9	0.1	0.3	0.1	0.1	0.2	0.2	1.5	1.2	-0.1	0.6	1.0	0.1	0.5	1.3	0.2	-0.0	-0.1	0.3	-0.4
Ever had hysterectomy (womb removed)	0.4	0.5	1.9	0.8	-0.4	-0.1	0.6	0.6	0.6	0.6	0.5	-0.2	-0.2	-0.7	-1.4	-0.6	-0.5	-0.8	0.6	-0.4	-0.6	-0.7	-0.7	-1.4	-0.6
Hearing difficulty/problems with background noise	0.4	0.6	1.6	-0.8	-0.3	-0.0	-1.1	-1.2	-1.1	-0.9	-0.9	-0.4	-0.4	0.2	-0.3	0.5	0.5	-0.3	-1.3	-0.2	1.2	0.9	0.8	1.0	1.0
Pulse rate	0.4	0.6	3.1	0.5	-0.0	-1.8	-0.0	0.4	0.1	0.1	0.2	-1.6	-1.3	-0.6	-0.9	-1.6	-0.6	-0.3	0.2	-0.9	-0.6	-0.5	-0.3	-0.0	0.3
Birth weight of first child	0.4	0.8	6.5	-0.2	0.8	0.1	0.1	0.5	0.2	0.0	0.6	-0.0	2.6	1.8	0.8	-0.1	1.2	1.4	0.5	1.2	-0.4	-0.1	0.4	0.0	-0.4
Blood clot in the leg (DVT)	0.4	0.5	2.2	-0.6	0.0	0.0	-0.6	-0.4	-0.6	-0.5	-0.4	0.6	1.5	1.4	0.7	0.1	1.3	1.0	-0.5	0.2	0.4	0.3	0.5	0.4	0.3
Chronic bronchitis/emphysema (mother)	0.4	0.5	2.0	-0.3	1.2	1.1	0.1	0.3	0.1	0.1	-0.0	1.3	1.4	0.7	-0.2	1.1	0.9	0.4	0.4	0.8	-0.3	-0.5	-0.1	-0.2	-0.4
Medication: Ibuprofen	0.4	0.4	1.8	0.4	1.2	1.0	0.6	0.7	0.5	0.6	0.0	1.1	0.6	-0.1	0.7	0.6	0.0	0.2	0.8	1.3	-0.2	0.0	-0.1	-0.2	-0.6
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.4	0.4	1.1	0.9	-0.2	-0.3	0.5	0.2	0.5	0.6	0.2	-1.0	-0.8	-0.5	-1.0	-1.0	-0.8	-1.0	0.4	-0.0	-0.6	-0.7	-0.7	-0.6	-0.3
Supplements: Vitamin C	0.4	0.4	1.8	-0.5	0.8	1.1	-0.2	-0.3	-0.2	-0.2	-0.4	1.3	0.8	0.6	0.0	1.3	0.7	0.3	-0.2	0.9	0.5	0.5	0.5	-0.2	-0.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.4	0.5	3.3	-0.6	1.8	0.5	-0.2	-0.2	-0.1	-0.3	-0.9	0.5	0.6	0.6	0.3	0.8	0.6	1.0	-0.0	1.6	0.4	0.4	0.3	0.5	-0.0
Commuting to job workplace: Walk	0.4	0.4	2.2	0.3	-1.0	-0.7	0.1	0.1	0.1	0.1	0.7	-1.5	-0.9	-1.0	0.6	-0.8	-1.0	0.0	0.1	-0.7	-0.1	-0.4	-0.6	0.5	0.3
Medication for cholesterol	0.4	0.6	2.1	1.0	-0.8	-0.3	0.7	0.8	0.8	0.7	0.5	0.5	-0.7	-1.5	-0.2	-0.7	-1.3	-0.5	0.6	-1.2	-0.6	-0.6	-0.8	-1.1	-0.7
Back pain experienced in last month	0.4	0.5	2.0	-0.4	0.7	1.1	-0.1	0.1	-0.1	-0.1	-0.1	0.7	1.3	1.1	0.9	1.1	0.9	1.2	0.1	1.4	0.4	0.1	0.1	0.0	-0.2
Number of operations (self-reported)	0.4	0.6	1.9	-0.7	0.3	-0.7	-0.9	-0.9	-0.9	-0.8	-1.4	-0.4	-0.9	0.6	-0.1	-0.0	1.1	-0.3	-0.9	-0.0	0.9	0.7	0.6	1.0	0.8
Bipolar Disorder (2018)	0.3	0.4	3.0	0.1	-1.2	0.2	0.2	0.4	0.3	0.2	-0.2	-0.2	0.9	0.2	1.7	0.3	-0.3	1.7	0.3	0.4	-0.1	0.2	0.1	0.0	0.0
Schizophrenia vs Biploar Disorder	0.3	0.4	2.4	0.4	1.0	0.7	0.7	0.4	0.6	0.7	0.6	-0.4	0.4	0.6	-0.5	0.2	0.6	-0.5	0.6	1.6	-0.5	-0.4	-0.3	-0.1	-0.6
Coronary Artery Disease (CAD)	0.3	0.4	2.6	0.0	-0.5	-0.4	-0.2	-0.3	-0.3	-0.1	-0.1	-1.3	-0.4	-0.0	-1.1	-0.3	0.2	-1.6	-0.3	-0.7	0.2	0.3	0.3	0.9	0.5
HDL Cholesterol	0.3	0.5	2.4	0.4	-0.4	-1.5	-0.3	-0.3	-0.2	-0.2	-1.3	-1.0	-0.8	-0.1	-0.9	-1.6	-0.4	-0.0	-0.1	-1.0	-0.1	-0.0	0.0	0.1	0.3
Triglycerides	0.3	0.5	2.3	0.3	-1.1	0.9	0.3	0.4	0.5	0.3	0.9	0.5	-0.2	-1.5	0.7	0.2	-1.3	-0.6	0.0	-0.4	-0.2	-0.5	-0.8	-0.5	-0.3
Blood Red Count	0.3	2.4	5.9	-1.7	1.9	-0.5	-1.8	-1.4	-1.7	-1.7	-1.1	0.4	0.5	1.7	1.4	1.1	1.7	2.4	-1.4	1.6	1.8	1.7	1.7	2.0	1.5
Hair Pigment	0.3	8.6	16.7	-3.7	-0.2	-1.9	-3.7	-3.9	-3.7	-3.9	-3.3	-0.7	-1.4	0.7	1.9	1.2	0.6	1.1	-3.8	-1.3	3.8	4.1	4.0	3.9	3.8
Tanning	0.3	3.3	6.4	-2.4	-0.3	-0.9	-2.3	-2.1	-2.4	-2.4	-2.5	-0.2	-1.4	0.4	0.8	0.9	0.5	1.3	-2.3	-0.9	2.5	2.2	1.9	2.5	2.3
Medication for hormone replacement therapy	0.3	0.3	0.6	-0.7	0.6	0.0	-0.6	-0.6	-0.7	-0.7	-0.4	-0.4	0.6	0.8	-0.3	0.5	0.3	0.3	-0.4	0.8	0.7	0.6	0.6	0.7	0.7
High blood pressure (mother)	0.3	0.4	1.8	-0.6	1.0	0.4	-0.2	-0.3	-0.2	-0.3	-0.1	0.6	1.1	1.3	0.6	0.7	0.8	0.5	-0.1	1.2	0.2	0.4	0.6	0.4	0.1
Qualifications: None of the above	0.3	0.7	4.8	-0.9	0.2	-1.0	-0.8	-1.2	-0.8	-0.9	-2.2	-0.1	-0.3	1.1	-0.1	-0.1	0.5	0.2	-1.0	0.5	0.2	0.6	1.1	0.9	0.9
Time employed in main current job	0.3	0.3	2.4	0.4	-1.6	-0.7	0.3	0.2	0.3	0.3	0.2	-0.1	-0.5	0.4	0.8	-0.8	0.3	0.6	0.2	-0.8	-0.4	-0.4	-0.4	-0.3	-0.3
Exposure to tobacco smoke at home	0.3	0.4	2.1	-0.2	-1.2	-0.8	-0.4	-0.5	-0.4	-0.4	0.1	-0.6	-0.7	-0.9	0.1	-0.3	-1.5	0.1	-0.5	-0.4	0.4	0.7	0.5	0.3	0.7
Seen doctor (GP) for nerves, anxiety, tension or depression	0.3	0.5	2.3	0.6	0.5	1.5	0.5	0.8	0.6	0.9	0.7	0.1	0.7	0.5	0.7	0.7	0.8	0.8	0.6	1.0	-0.2	-0.5	-0.7	-0.2	-0.9
Number of full brothers	0.3	0.4	2.1	0.1	-0.6	-0.8	-0.4	-0.5	-0.4	-0.3	-0.7	-0.4	-1.0	-1.2	-0.4	-0.6	-1.1	-0.4	-0.6	-1.4	0.3	0.0	-0.2	-0.3	0.5
Emphysema/chronic bronchitis	0.3	0.3	1.7	-0.7	0.6	0.1	-0.5	-0.5	-0.6	-0.5	-1.3	0.7	-0.0	0.2	0.6	0.6	0.3	0.9	-0.6	0.7	0.5	0.4	0.4	0.4	0.5
Medication: Omeprazole	0.3	0.4	0.9	0.4	0.8	0.4	0.8	0.6	0.8	0.7	0.2	-0.2	-0.7	-0.3	1.0	0.0	-0.2	0.8	0.8	0.7	-0.4	-0.6	-0.9	-0.4	-0.8
Osteoarthritis (self-reported)	0.3	0.4	1.9	-0.1	0.8	0.6	0.2	-0.0	0.2	0.2	-1.0	1.4	0.2	0.6	1.0	0.7	1.1	0.5	0.0	0.6	-0.1	-0.2	-0.1	0.3	-0.5
Medication: Gliclazide	0.3	0.4	1.5	-0.7	-0.4	-0.5	-0.7	-0.9	-0.8	-0.7	-1.2	0.0	-0.1	0.5	0.1	0.1	0.1	0.4	-0.7	0.2	0.4	0.2	0.4	0.9	0.9
Hearing aid user	0.3	0.4	1.2	-0.7	0.8	-1.1	-0.9	-0.6	-0.8	-0.8	-0.1	-0.1	0.5	0.8	-1.0	-0.3	0.6	0.3	-0.6	-0.1	0.2	0.3	0.6	0.2	0.7
Mother’s age at death	0.3	0.4	1.4	-0.3	-0.4	-1.1	-0.5	-0.6	-0.6	-0.6	0.1	-0.6	-0.9	-0.7	0.6	-0.5	-0.5	-0.6	-0.5	-1.2	0.5	0.5	0.4	0.5	0.8
Tinnitus: Yes, now most or all of the time	0.3	0.3	1.7	-0.1	-0.9	-0.3	-0.2	-0.2	-0.2	-0.2	0.4	-1.3	-1.0	-0.9	-0.5	-0.2	-0.9	-0.2	-0.3	-0.3	0.2	0.5	0.4	0.8	0.6
Medication: Lisinopril	0.3	0.4	1.1	0.3	0.3	0.3	0.6	0.6	0.6	0.6	0.6	0.5	0.5	0.9	0.7	0.2	1.0	-0.5	0.6	-0.1	-0.5	-0.8	-0.9	-0.6	-0.8
Vascular/heart problems diagnosed by doctor	0.3	0.7	5.4	0.3	-1.4	-0.1	-0.1	-0.0	-0.0	-0.1	0.8	-0.0	-0.8	-2.3	0.1	-0.1	-2.2	-0.4	-0.3	-1.3	0.0	-0.0	-0.3	-0.2	0.3
Heart disease (siblings)	0.3	0.4	2.3	-0.3	1.1	0.5	0.2	0.3	0.2	0.1	-0.4	-0.4	0.7	1.0	0.5	0.6	0.7	1.0	0.3	1.5	0.2	-0.0	-0.3	0.2	-0.3
Major Depression (MDD)	0.2	0.3	1.1	0.3	-1.0	-1.0	0.0	0.1	0.0	0.1	1.0	-1.0	-0.8	-0.3	0.1	-0.8	-0.3	-0.1	-0.1	-0.2	-0.5	-0.4	-0.3	0.2	0.3
Ovarian Cancer	0.2	0.3	0.9	-0.4	0.1	-0.9	-0.7	-0.6	-0.7	-0.7	-0.6	-0.7	-0.6	-0.6	-0.6	-0.5	-0.4	-0.6	-0.6	-0.8	0.5	0.1	0.0	-0.1	0.6
Ulcerative Colitis	0.2	0.2	0.7	0.5	0.6	0.8	0.6	0.7	0.7	0.8	-0.1	0.2	0.4	0.3	0.3	0.5	0.5	0.1	0.5	0.8	-0.2	-0.2	-0.2	0.5	-0.4
Waist Hip Ratio (WHR)	0.2	0.8	5.5	-0.2	2.3	1.5	-0.1	-0.1	-0.2	0.1	0.3	0.6	0.1	0.1	-0.2	1.4	0.6	-0.8	-0.1	2.3	0.7	0.1	-0.3	0.1	-0.2
Systolic Blood Pressure	0.2	0.8	5.2	-0.4	0.6	0.6	-0.3	-0.3	-0.4	-0.2	-0.3	-0.9	1.6	1.6	0.1	1.0	0.8	1.5	-0.1	2.3	0.7	0.8	0.8	-0.0	-0.1
Medication: Metformin	0.2	0.3	1.0	-0.6	-0.4	0.5	-0.2	-0.4	-0.2	-0.2	-0.9	1.0	0.6	0.7	-0.1	0.8	0.8	0.2	-0.2	-0.2	0.2	0.2	0.3	0.6	0.1
Severe depression (siblings)	0.2	0.2	0.9	0.4	0.1	0.4	0.4	0.4	0.5	0.4	-0.0	0.1	0.3	-0.0	0.4	0.3	-0.4	0.4	0.5	0.4	-0.5	-0.5	-0.4	-1.0	-0.5
Bilateral oophorectomy (both ovaries removed)	0.2	0.2	0.8	-0.4	0.5	0.7	0.0	0.2	-0.0	-0.1	-0.0	0.3	0.7	0.7	-0.6	0.9	0.7	0.7	0.1	0.4	0.2	0.3	0.3	-0.0	-0.2
High blood pressure	0.2	0.4	1.8	0.3	0.7	-0.4	0.5	0.5	0.4	0.5	-0.3	-0.7	0.2	1.3	-0.9	-0.7	1.2	-0.6	0.7	0.6	-0.7	-0.7	-0.4	-0.4	-0.5
Had menopause	0.2	0.2	0.8	-0.4	0.3	-0.9	-0.5	-0.4	-0.5	-0.6	0.2	-0.1	-0.1	0.6	0.4	-0.4	0.7	-0.5	-0.3	-0.5	0.4	0.2	0.1	0.5	0.6
Forced vital capacity (FVC)	0.2	0.9	2.6	0.9	0.6	1.4	1.1	1.6	1.3	1.1	1.6	0.4	0.9	-0.4	1.1	0.6	-0.2	0.6	1.3	0.1	-0.5	-0.3	-0.6	-0.7	-1.4
Financial difficulties in last 2 years	0.2	0.3	1.7	0.3	-0.1	0.2	-0.1	-0.2	-0.1	-0.0	-0.0	0.2	-0.8	-1.2	-0.3	-0.0	-1.2	-1.3	-0.2	-0.7	0.1	-0.2	-0.3	-0.5	0.1
Pain all over the body in last month	0.2	0.2	0.8	-0.6	0.2	0.3	-0.4	-0.4	-0.4	-0.4	-0.3	-0.4	0.4	0.1	0.2	0.6	0.1	0.5	-0.4	0.4	0.4	0.7	0.9	0.4	0.4
Medication: Ramipril	0.2	0.3	2.0	0.1	0.9	0.5	0.3	0.3	0.2	0.4	-0.2	0.3	1.2	0.8	0.2	0.1	0.5	0.3	0.5	1.4	-0.2	-0.3	-0.2	0.1	-0.2
Hair/balding pattern: Pattern 3	0.2	0.2	1.7	-0.2	-0.0	-0.7	-0.1	-0.1	-0.1	-0.2	-0.4	-1.3	-0.2	0.5	-0.8	-0.8	0.8	0.4	-0.1	-0.6	-0.1	0.1	0.3	0.3	0.2
Medication: Ibuprofen (e.g. Nurofen)	0.2	0.3	1.7	0.2	0.6	0.9	0.2	0.4	0.2	0.3	0.1	1.1	0.8	-0.1	0.7	0.8	-0.2	0.1	0.4	1.3	0.1	0.2	0.1	0.1	-0.2
Qualifications: O levels/GCSEs or equivalent	0.2	0.3	1.8	0.0	-0.6	0.4	0.2	0.2	0.2	0.0	1.3	-0.0	-0.5	-1.2	0.4	0.6	-1.0	-0.2	0.1	-0.4	0.0	0.0	-0.2	0.0	0.1
Mouth/teeth dental problems: Bleeding gums	0.2	0.2	1.6	0.1	-0.0	-0.2	0.2	0.4	0.2	0.3	-0.7	0.5	0.4	0.5	-0.2	-0.1	0.6	1.3	0.2	0.5	-0.5	-0.4	-0.2	-0.3	-0.2
Medication for cholesterol, blood pressure or diabetes	0.2	0.3	2.1	0.4	0.3	0.2	0.2	0.2	0.2	0.2	0.5	-1.0	-0.7	-1.4	-0.6	0.1	-1.4	-0.6	0.2	-0.2	-0.1	-0.1	-0.3	-0.4	0.1
Pulse rate, automated reading	0.2	0.8	4.6	0.3	-0.1	-2.1	-0.5	0.0	-0.4	-0.2	-0.8	-1.1	-1.8	0.1	-0.7	-1.9	0.5	-0.3	-0.1	-1.3	-0.4	-0.4	0.1	0.1	0.6
Knee pain experienced in last month	0.2	0.4	1.2	-0.7	0.8	-0.1	-0.5	-0.5	-0.5	-0.5	-0.8	0.5	0.7	0.9	0.4	0.4	1.1	0.8	-0.6	0.5	0.2	0.4	0.7	0.1	0.3
Hypertension (Self-reported)	0.2	0.7	1.2	0.7	0.8	-0.3	0.9	0.8	0.8	0.9	0.0	-0.8	0.2	1.1	-1.0	-0.9	1.0	-0.8	1.1	0.7	-1.1	-1.1	-0.8	-0.7	-0.8
Handedness (chirality/laterality): Left-handed	0.2	0.2	1.2	-0.1	-0.3	-0.7	-0.5	-0.2	-0.4	-0.4	-0.4	-0.7	-0.5	-0.8	0.0	-0.5	-1.1	-0.2	-0.3	0.1	0.3	0.4	0.3	0.4	0.7
Ever had bowel cancer screening	0.2	0.3	1.3	0.1	0.6	-0.9	0.1	0.0	0.1	0.1	-1.1	-0.7	-0.5	0.7	-0.8	-0.9	0.5	0.0	0.3	0.2	-0.7	-0.4	-0.0	0.5	0.1
Wears glasses or contact lenses	0.2	0.3	2.1	0.3	-0.2	-0.2	0.2	0.7	0.3	0.3	0.7	-0.5	0.9	-0.1	-1.4	-0.6	0.0	0.1	0.5	-0.2	-0.9	-0.6	-0.2	-0.1	-0.2
Medication: Atorvastatin	0.2	0.2	0.7	0.2	-0.2	0.6	0.3	0.3	0.4	0.4	0.7	0.0	0.8	0.7	-0.3	0.3	0.8	-0.5	0.3	0.3	-0.3	-0.4	-0.3	0.2	-0.4
Blood White Count	0.1	0.9	4.6	0.1	1.6	-2.0	-0.5	-0.6	-0.6	-0.4	-0.7	-2.1	-0.7	0.6	-1.1	-1.4	-0.1	-0.8	-0.3	1.2	-0.0	-0.2	-0.1	0.5	0.8
Other serious medical condition/disability diagnosed by doctor	0.1	0.1	0.7	0.1	-0.1	0.7	0.2	0.1	0.2	0.3	-0.1	0.8	-0.7	0.1	0.7	0.3	0.6	0.1	0.1	-0.1	0.1	-0.1	-0.2	-0.2	-0.4
Falls in the last year	0.1	0.1	0.3	0.2	-0.1	0.6	0.0	0.2	0.1	0.2	-0.4	0.5	-0.0	-0.0	-0.3	0.3	0.2	0.2	0.1	0.4	0.4	0.2	-0.1	-0.2	-0.2
Forced vital capacity (FVC), Best measure	0.1	0.5	2.0	0.5	0.4	1.3	0.7	1.0	0.8	0.6	1.4	0.1	0.8	-0.6	1.1	1.0	-0.4	0.6	0.8	0.0	-0.0	0.3	0.0	-0.3	-0.9
Reason for reducing amount of alcohol drunk: Health precaution	0.1	0.2	1.5	-0.2	-0.9	-0.3	-0.1	-0.3	-0.1	-0.2	-0.3	-0.2	-0.2	0.4	1.2	-0.1	0.1	0.7	-0.2	-0.2	0.4	0.2	0.0	0.1	0.1
Medication: Blood pressure	0.1	0.2	0.8	0.3	-0.8	-0.7	0.4	0.3	0.4	0.4	0.0	0.3	-0.3	0.8	0.6	-0.9	0.9	0.2	0.3	-0.5	-0.4	-0.2	-0.1	0.1	-0.3
Leg pain on walking	0.1	0.1	0.8	-0.5	-0.1	-0.3	-0.2	-0.4	-0.2	-0.3	-0.2	-0.3	-0.4	0.1	-0.0	0.2	0.1	-0.4	-0.4	-0.1	0.1	0.6	0.7	0.9	0.4
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.1	0.1	0.5	0.4	-0.2	-0.2	0.0	0.1	0.0	0.2	0.1	-0.5	0.1	0.3	-0.1	-0.7	-0.1	0.1	0.2	0.4	-0.2	-0.2	-0.3	0.0	0.1
Medication: Blood pressure	0.1	0.3	2.1	-0.1	0.8	0.1	0.2	0.0	0.1	0.1	-0.4	-0.2	0.4	1.4	0.1	0.2	1.4	-0.1	0.3	0.9	-0.2	-0.2	-0.0	0.3	-0.2
LDL Cholesterol	0.0	0.0	0.3	0.1	-0.4	-0.0	0.1	-0.2	-0.2	0.1	-0.1	0.1	-0.1	-0.0	0.5	-0.1	-0.4	0.1	-0.2	0.3	0.1	0.1	0.1	-0.1	0.0

Hub : Genes

POLR3H

Models

Trait associations