Best TWAS P=1.96e-08 · Best GWAS P=7.28e-08 conditioned to 0.338
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Cerebellar Hemisphere | STMN3 | 0.39 | 0.08 | lasso | 5 | 0.22 | 2.1e-06 | -4.3 | -5.2 | 2.2e-07 | 0.64 | 0.14 | 0.62 | FALSE |
| 2 | GTEx | Testis | RTEL1 | 0.19 | 0.06 | lasso | 5 | 0.14 | 8.0e-07 | -4.2 | -5.1 | 2.6e-07 | 0.63 | 0.13 | 0.70 | FALSE |
| 3 | YFS | Blood | LIME1 | 0.12 | 0.19 | enet | 15 | 0.19 | 5.3e-59 | -5.1 | -5.2 | 2.2e-07 | 0.98 | 0.01 | 0.99 | FALSE |
| 4 | The Cancer Genome Atlas | Ovarian Serous Cystadenocarcinoma | RTEL1 | 0.05 | 0.04 | blup | 56 | 0.03 | 4.2e-03 | -4.4 | -5.6 | 2.0e-08 | 0.88 | 0.01 | 0.79 | TRUE |
| 5 | The Cancer Genome Atlas | Ovarian Serous Cystadenocarcinoma | TNFRSF6B | 0.05 | 0.02 | blup | 44 | 0.03 | 2.9e-03 | -5.4 | -5.2 | 1.6e-07 | 0.93 | 0.01 | 0.73 | FALSE |
| 6 | The Cancer Genome Atlas | Prostate Adenocarcinoma | ARFRP1 | 0.03 | 0.02 | lasso | 2 | 0.02 | 1.2e-03 | -5.2 | 5.2 | 1.7e-07 | -0.98 | 0.01 | 0.96 | FALSE |