Best TWAS P=4.83e-10 · Best GWAS P=2.7e-09 conditioned to 0.608
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | NOB1 | 0.04 | 0.05 | enet | 12 | 0.04 | 7.2e-06 | -5.6 | 5.8 | 7.6e-09 | -0.90 | 0.02 | 0.98 | FALSE |
| 2 | GTEx | Brain Cerebellum | NOB1 | 0.15 | 0.08 | lasso | 3 | 0.07 | 3.7e-03 | -5.9 | 6.2 | 4.8e-10 | -0.92 | 0.01 | 0.86 | TRUE |
| 3 | GTEx | Brain Cerebellum | CTD-2033A16.3 | 0.14 | 0.15 | lasso | 4 | 0.12 | 2.2e-04 | -5.7 | 6.1 | 1.1e-09 | -0.93 | 0.01 | 0.93 | FALSE |
| 4 | METSIM | Adipose | NOB1 | 0.03 | 0.03 | lasso | 2 | 0.03 | 2.8e-05 | -5.9 | 6.1 | 1.3e-09 | -0.97 | 0.01 | 0.99 | FALSE |