[Hub]/) : Traits : Past tobacco smoking : ← →

chr6:110,588,546-112,621,834

Best TWAS P=1.32e-15 · Best GWAS P=9e-18 conditioned to 0.345

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex REV3L 0.15 0.10 lasso 5 0.14 9.8e-17 -7.1 -6.6 3.9e-11 0.74 0.83 0.17 FALSE
2 GTEx Adipose Subcutaneous RP5-1112D6.4 0.08 0.03 lasso 4 0.03 2.1e-03 -6.3 -7.0 1.9e-12 0.84 0.04 0.95 TRUE
3 GTEx Artery Aorta RP5-1112D6.4 0.15 0.01 lasso 7 0.02 3.5e-02 -7.3 -6.4 1.1e-10 0.72 0.06 0.74 FALSE
4 GTEx Brain Cerebellum REV3L 0.31 0.04 lasso 11 0.12 2.4e-04 -8.4 -7.9 3.0e-15 0.85 0.02 0.92 FALSE
5 GTEx Brain Hypothalamus GTF3C6 0.32 0.04 lasso 4 0.08 6.8e-03 -8.5 8.0 1.3e-15 -0.90 0.02 0.84 TRUE
6 GTEx Breast Mammary Tissue (Female) C6orf3 0.32 0.06 lasso 6 0.02 6.2e-02 -4.7 -5.1 2.9e-07 0.40 0.09 0.13 FALSE
7 GTEx Cells Transformed fibroblasts RP5-1112D6.4 0.15 0.06 lasso 2 0.06 4.0e-05 -6.3 -6.8 7.7e-12 0.81 0.09 0.86 FALSE
8 GTEx Colon Transverse RP5-1112D6.4 0.11 0.10 lasso 4 0.06 7.1e-04 -7.3 -7.5 6.1e-14 0.81 0.35 0.14 FALSE
9 GTEx Esophagus Gastroesophageal Junction C6orf3 0.27 0.01 lasso 6 0.05 8.1e-03 1.3 -5.4 7.1e-08 0.34 0.09 0.52 TRUE
10 GTEx Pituitary RP5-1112D6.4 0.23 0.16 lasso 4 0.13 4.4e-04 -5.5 -6.6 4.8e-11 0.79 0.09 0.60 FALSE
11 GTEx Thyroid RP5-1112D6.4 0.13 0.05 enet 16 0.06 1.4e-05 -5.5 -5.5 3.5e-08 0.72 0.82 0.13 FALSE
12 ROSMAP Brain Pre-frontal Cortex REV3L 0.16 0.16 bslmm 468 0.18 1.9e-22 -7.3 -6.4 1.3e-10 0.73 0.42 0.58 FALSE
13 The Cancer Genome Atlas Breast Invasive Carcinoma KIAA1919 0.09 0.06 lasso 3 0.06 1.0e-11 -5.5 -5.2 1.8e-07 0.69 1.00 0.00 FALSE