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chr6:110,588,546-112,621,834

Best TWAS P=1.32e-15 · Best GWAS P=9e-18 conditioned to 0.345

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
5	GTEx	Brain Hypothalamus	GTF3C6	0.32	0.04	lasso	4	0.08	6.8e-03	-8.5	8.0	1.3e-15	-0.90	0.02	0.84	TRUE
2	GTEx	Adipose Subcutaneous	RP5-1112D6.4	0.08	0.03	lasso	4	0.03	2.1e-03	-6.3	-7.0	1.9e-12	0.84	0.04	0.95	TRUE
9	GTEx	Esophagus Gastroesophageal Junction	C6orf3	0.27	0.01	lasso	6	0.05	8.1e-03	1.3	-5.4	7.1e-08	0.34	0.09	0.52	TRUE
4	GTEx	Brain Cerebellum	REV3L	0.31	0.04	lasso	11	0.12	2.4e-04	-8.4	-7.9	3.0e-15	0.85	0.02	0.92	FALSE
8	GTEx	Colon Transverse	RP5-1112D6.4	0.11	0.10	lasso	4	0.06	7.1e-04	-7.3	-7.5	6.1e-14	0.81	0.35	0.14	FALSE
7	GTEx	Cells Transformed fibroblasts	RP5-1112D6.4	0.15	0.06	lasso	2	0.06	4.0e-05	-6.3	-6.8	7.7e-12	0.81	0.09	0.86	FALSE
1	CommonMind	Brain Pre-frontal Cortex	REV3L	0.15	0.10	lasso	5	0.14	9.8e-17	-7.1	-6.6	3.9e-11	0.74	0.83	0.17	FALSE
10	GTEx	Pituitary	RP5-1112D6.4	0.23	0.16	lasso	4	0.13	4.4e-04	-5.5	-6.6	4.8e-11	0.79	0.09	0.60	FALSE
3	GTEx	Artery Aorta	RP5-1112D6.4	0.15	0.01	lasso	7	0.02	3.5e-02	-7.3	-6.4	1.1e-10	0.72	0.06	0.74	FALSE
12	ROSMAP	Brain Pre-frontal Cortex	REV3L	0.16	0.16	bslmm	468	0.18	1.9e-22	-7.3	-6.4	1.3e-10	0.73	0.42	0.58	FALSE
11	GTEx	Thyroid	RP5-1112D6.4	0.13	0.05	enet	16	0.06	1.4e-05	-5.5	-5.5	3.5e-08	0.72	0.82	0.13	FALSE
13	The Cancer Genome Atlas	Breast Invasive Carcinoma	KIAA1919	0.09	0.06	lasso	3	0.06	1.0e-11	-5.5	-5.2	1.8e-07	0.69	1.00	0.00	FALSE
6	GTEx	Breast Mammary Tissue (Female)	C6orf3	0.32	0.06	lasso	6	0.02	6.2e-02	-4.7	-5.1	2.9e-07	0.40	0.09	0.13	FALSE