TWAS hub - REV3L

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.147	0.036	1.9e-11	0.104	0.112	0.120	0.127	0.140	1.4e-12	1.6e-13	1.9e-14	3.1e-15	9.8e-17
2	GTEx	Brain Cerebellum	0.312	0.103	7.6e-04	0.044	NA	0.098	NA	0.118	1.9e-02	NA	8.2e-04	NA	2.4e-04
3	GTEx	Brain Putamen basal ganglia	0.305	0.113	5.0e-03	-0.010	NA	-0.010	NA	-0.012	6.8e-01	NA	6.8e-01	NA	8.2e-01
4	ROSMAP	Brain Pre-frontal Cortex	0.160	0.034	0.0e+00	0.160	0.178	0.173	0.179	0.169	4.2e-20	2.2e-22	9.9e-22	1.9e-22	3.6e-21

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	4
Past tobacco smoking	20.1	36.8	62.3	-6.6	-7.9	-6.4
Smoking Status	16.7	39.9	75.9	6.4	8.7	6.5
Ever smoked	15.4	27.1	47.6	5.6	6.9	5.4
Smoking status: Previous	13.1	19.6	33.6	5.0	5.8	4.4
Long-standing illness, disability or infirmity	8.4	12.9	20.9	4.6	4.5	3.2
Maternal smoking around birth	6.5	9.4	18.4	2.8	4.3	3.4
Medication for pain relief, constipation, heartburn	5.4	9.2	18.6	-3.3	-4.3	-2.6
Worrier / anxious feelings	5.1	9.7	14.9	-3.3	-3.9	-3.6
Medication for hormone replacement therapy	5.0	5.6	9.0	2.2	3.0	2.9
Current tobacco smoking	4.9	8.0	17.4	2.3	4.2	3.0
Smoking status: Current	4.7	7.5	16.2	2.0	4.0	3.1
Number of self-reported non-cancer illnesses	4.2	7.3	11.0	3.1	3.3	2.9
Medication: Lansoprazole	3.8	4.3	7.0	2.5	2.6	2.1
Leg fat percentage (right)	3.8	13.8	26.0	4.2	5.1	3.4
Commuting to job workplace: Cycle	3.8	4.6	7.7	-2.7	-2.8	-1.8
Taking other prescription medications	3.7	5.8	8.2	2.9	2.8	2.7
Frequency of tenseness / restlessness in last 2 weeks	3.7	5.8	9.7	-3.1	-2.9	-2.3
Exposure to tobacco smoke at home	3.7	4.1	7.3	2.7	2.0	2.3
Chronic bronchitis/emphysema (father)	3.6	4.2	6.0	2.4	2.2	2.5
Worry (Nagel 2018)	3.5	7.3	10.8	-3.0	-3.1	-3.3
Ever used hormone-replacement therapy (HRT)	3.5	4.5	10.7	2.2	1.6	3.3
Leg fat percentage (left)	3.5	12.5	24.3	4.0	4.9	3.2
Pulse wave reflection index	3.4	4.2	7.1	1.9	2.7	2.5
Medication for cholesterol	3.4	5.2	9.6	-2.4	-3.1	-2.3
Number of treatments/medications taken	3.3	5.9	11.0	2.8	3.3	2.2
Average weekly beer plus cider intake	3.3	4.7	10.0	2.4	3.2	1.8
Frequency of depressed mood in last 2 weeks	3.2	4.5	8.9	-3.0	-1.9	-2.3
Leg fat mass (right)	2.9	11.4	18.3	3.9	4.3	3.5
Average weekly red wine intake	2.9	4.3	9.4	-2.0	-3.1	-1.9
Financial situation satisfaction	2.9	3.6	7.2	-2.7	-2.0	-1.8
Nervous feelings	2.8	5.3	10.0	-2.3	-2.4	-3.2
Illnesses of father: High blood pressure	2.8	3.5	5.8	-2.1	-2.4	-1.9
Reaction Time	2.7	5.1	9.2	-3.0	-1.5	-3.0
Suffer from ‘nerves’	2.7	4.2	6.5	-2.4	-2.5	-2.2
Leg fat mass (left)	2.7	10.5	17.1	3.6	4.1	3.4
Type 2 Diabetes (T2D) (2012)	2.6	3.0	9.0	1.1	3.0	1.3
Medication: Metformin	2.6	3.7	7.7	1.7	2.8	2.0
Age started oral contraceptive pill	2.6	3.3	8.3	-1.5	-2.9	-1.6
Coronary Artery Disease (CAD)	2.5	2.9	6.1	2.0	1.2	2.5
Pulse wave peak to peak time	2.5	2.9	5.7	-1.9	-1.5	-2.4
Medication: Omeprazole	2.5	3.0	4.9	1.8	2.2	2.0
Forced expiratory volume in 1-second (FEV1)	2.4	8.0	12.7	-3.2	-3.6	-3.0
Mouth/teeth dental problems: Dentures	2.3	3.9	6.9	2.6	2.1	2.1
Commuting to job workplace: Walk	2.3	2.5	5.0	-1.3	-2.2	-1.8
Commuting to job workplace: Public transport	2.3	2.8	5.1	-2.3	-1.7	-1.7
Body fat percentage	2.2	8.6	18.7	3.1	4.3	2.5
Number of full sisters	2.2	2.7	5.1	2.2	2.2	1.0
Had major operations	2.2	2.6	4.4	2.1	1.9	1.5
Medication: Aspirin	2.2	2.9	7.3	1.8	2.7	1.0
Medication: Omeprazole (e.g. Zanprol)	2.2	2.7	4.5	1.7	2.1	1.8
Exposure to tobacco smoke outside home	2.1	2.8	5.5	2.1	1.2	2.3
Trunk fat percentage	2.0	7.9	17.1	2.8	4.1	2.5
Medication: Ibuprofen (e.g. Nurofen)	2.0	2.5	4.7	2.2	2.2	0.9
Pulse wave Arterial Stiffness index	2.0	2.3	5.2	1.7	1.1	2.3
Number of full brothers	2.0	2.6	5.6	2.0	2.4	0.8
Whole body fat mass	2.0	8.2	14.1	3.1	3.8	3.0
Forced vital capacity (FVC)	1.9	7.3	15.4	-2.9	-3.9	-2.3
Forced expiratory volume in 1-second (FEV1), Best measure	1.9	6.2	10.2	-3.2	-3.0	-2.3
Tense / ‘highly strung’	1.8	3.0	5.3	-1.9	-2.3	-1.8
Peak expiratory flow (PEF)	1.8	4.2	6.8	-2.5	-2.0	-2.6
Supplements: Calcium	1.8	1.9	3.4	-1.8	-1.8	-1.1
Serious illness, injury or assault to yourself	1.7	2.1	3.7	1.9	1.4	1.6
Father’s age at death	1.7	2.3	3.4	-1.7	-1.8	-1.7
Age at last live birth	1.7	2.4	4.6	-1.7	-1.4	-2.1
Guilty feelings	1.7	2.6	4.5	-1.7	-1.7	-2.1
Alcohol drinker status: Never	1.7	2.1	4.9	1.2	2.2	1.4
Number of operations (self-reported)	1.7	2.6	4.0	2.0	1.6	2.0
Pain experienced in last month	1.7	2.9	6.4	-2.5	-1.7	-1.5
Body mass index (BMI)	1.6	6.8	13.5	2.8	3.7	2.5
Qualifications: O levels/GCSEs or equivalent	1.6	2.6	5.4	-2.0	-2.3	-1.0
Forced vital capacity (FVC), Best measure	1.6	5.8	11.6	-2.9	-3.4	-1.8
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.6	1.9	3.3	1.3	1.6	1.8
Loneliness, isolation	1.6	2.2	5.0	-1.6	-2.2	-1.2
Pain type(s) experienced in last month: Hip pain	1.6	2.0	6.8	0.9	2.6	0.6
Lung FVC	1.5	7.5	12.5	-3.3	-2.6	-3.5
Tinnitus: Yes, but not now, but have in the past	1.5	1.6	3.4	1.3	1.2	1.8
Waist circumference	1.5	5.4	8.0	2.8	2.8	2.4
Medication: Paracetamol	1.5	2.5	4.8	2.2	1.5	1.6
Fractured/broken bones in last 5 years	1.5	1.9	4.1	1.8	0.7	2.0
Ulcerative Colitis (UC)	1.4	2.7	8.4	-2.9	-1.2	-1.0
Trunk fat mass	1.4	6.2	11.5	2.6	3.4	2.6
Noisy workplace	1.4	1.7	3.9	2.0	0.6	1.6
Age at first live birth	1.4	2.6	5.7	-1.7	-2.4	-1.2
Medication: Ibuprofen	1.4	1.7	3.7	1.6	1.9	0.7
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.4	1.7	2.7	1.6	1.6	1.3
Diabetes diagnosed by doctor	1.4	2.2	4.2	1.3	2.0	1.7
Friendships satisfaction	1.4	1.7	3.4	-1.8	-0.2	-1.9
Osteoarthritis (self-reported)	1.4	1.8	3.6	1.9	1.6	1.0
Mean Putamen Volume	1.3	1.5	3.7	-1.9	-1.1	-1.0
Hypothyroidism (self reported)	1.3	2.9	4.9	-2.2	-2.1	-1.4
Medication: Paracetamol	1.3	2.0	3.7	1.9	1.0	1.8
Risk taking	1.3	1.9	4.5	1.5	2.1	0.9
Alzheimer’s Disease (in father)	1.2	1.3	2.6	1.5	0.7	1.6
LDL Cholesterol	1.2	1.9	4.4	-2.1	-0.8	-1.7
Neuroticism (2016)	1.2	1.7	2.9	-1.7	-1.4	-1.4
Townsend deprivation index at recruitment	1.2	1.7	5.9	0.6	2.4	0.7
Had other major operations	1.2	1.5	3.5	0.5	1.5	1.9
Arm fat percentage (right)	1.2	4.9	12.0	2.2	3.5	1.7
Alcohol intake versus 10 years previously	1.2	1.8	2.9	1.4	1.7	1.5
Qualifications: A levels/AS levels or equivalent	1.2	2.6	7.7	-1.5	-2.8	-0.8
Arm fat mass (right)	1.2	4.8	9.4	2.2	3.1	2.2
Illness, injury, bereavement, stress in last 2 years	1.2	1.5	2.4	-1.0	-1.6	-1.6
Arm fat percentage (left)	1.2	5.0	12.3	2.2	3.5	1.7
Back pain experienced in last month	1.2	1.8	3.4	1.9	1.7	1.0
Average weekly champagne plus white wine intake	1.2	1.6	4.0	-1.5	-2.0	-0.6
Ever taken oral contraceptive pill	1.2	1.4	3.6	1.0	1.0	1.9
Alcohol drinker status: Previous	1.2	1.4	2.3	1.3	1.2	1.5
BMI	1.1	6.4	15.4	2.4	3.9	2.1
Neuroticism	1.1	2.7	4.5	-1.8	-2.1	-1.8
Diverticular disease/diverticulitis (self-reported)	1.1	1.3	3.4	-1.4	0.1	-1.9
Mouth/teeth dental problems	1.1	1.7	3.0	-1.7	-1.6	-1.1
Neuroticism score	1.1	2.3	3.5	-1.7	-1.6	-1.9
Worry too long after embarrassment	1.1	1.8	4.3	-1.6	-0.8	-2.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.1	2.3	4.6	-2.2	-1.6	-1.4
Arm fat mass (left)	1.1	4.7	10.1	2.2	3.2	1.9
Depression (Nagel 2018)	1.0	1.6	3.1	-1.8	-1.6	-0.7
Neuroticism (Nagel 2018)	1.0	2.5	3.6	-1.9	-1.7	-1.9
Schizophrenia vs Biploar Disorder	1.0	1.3	5.1	0.0	-2.3	0.3
Hair/balding pattern: Pattern 4	1.0	2.4	6.9	-2.6	-0.1	-1.7
Number of children fathered	1.0	1.2	2.5	-1.0	-1.1	-1.6
Knee pain experienced in last month	1.0	1.6	4.8	2.2	0.8	1.0
Allergy or Eczema	0.9	2.3	5.7	-1.8	0.3	-2.4
Hand grip strength (left)	0.9	2.3	7.7	-0.9	-2.8	-1.0
Sensitivity / hurt feelings	0.9	1.6	3.3	-1.6	-0.7	-1.8
Qualifications: CSEs or equivalent	0.9	1.2	2.2	-1.5	-1.0	-1.2
Alcohol usually taken with meals	0.9	1.4	2.7	-0.9	-1.4	-1.6
Medication: Ramipril	0.9	1.2	2.1	1.1	1.2	1.4
Weight	0.9	4.5	7.2	2.5	2.2	2.7
Hip circumference	0.9	4.0	6.6	2.4	1.8	2.6
Number of live births	0.9	1.3	4.1	-1.0	0.0	-2.0
Reason for reducing amount of alcohol drunk: Health precaution	0.9	1.0	3.3	-0.7	-1.8	-0.5
Medication: Blood pressure	0.9	1.6	3.7	1.6	0.5	1.9
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.9	1.0	2.5	1.6	-0.2	1.3
Average weekly spirits intake	0.8	1.0	2.5	-1.6	-0.8	-0.9
Bilateral oophorectomy (both ovaries removed)	0.8	0.9	2.4	1.2	0.0	1.5
Hayfever, allergic rhinitis or eczema	0.8	1.7	4.7	-1.2	0.9	-2.2
Multivitamins +/- minerals	0.8	1.0	1.8	-1.0	-1.3	-1.1
Financial difficulties in last 2 years	0.8	1.1	2.5	1.1	0.9	1.6
Fluid intelligence score	0.8	1.7	2.6	-1.6	-1.5	-1.5
Eye problems/disorders: None of the above	0.8	1.0	2.0	-0.8	-1.4	-1.1
Emphysema/chronic bronchitis	0.8	0.9	1.8	-1.4	-0.9	-1.0
Qualifications: nursing, teaching	0.8	1.2	2.2	-1.4	-0.9	-1.5
Vascular/heart problems diagnosed by doctor	0.8	2.3	6.0	-1.5	-1.0	-2.4
Cholesterol lowering medication	0.8	1.2	2.6	1.4	1.6	0.6
Major Depression (MDD)	0.7	0.9	1.5	1.2	1.2	0.7
Other serious medical condition/disability diagnosed by doctor	0.7	0.9	1.7	1.0	1.3	1.0
Had menopause	0.7	0.9	1.5	1.2	0.8	1.2
Hayfever/allergic rhinitis (self-reported)	0.7	1.0	3.4	-0.5	0.5	-1.8
Seen doctor (GP) for nerves, anxiety, tension or depression	0.7	1.1	3.6	0.9	0.1	1.9
Mouth/teeth dental problems: Bleeding gums	0.7	0.9	1.5	0.7	1.2	1.2
Shortness of breath walking on level ground	0.7	0.8	1.6	-1.2	-1.2	-0.3
Migraine (self-reported)	0.7	0.9	1.5	1.2	1.1	1.0
Medication: Aspirin	0.7	1.0	2.8	0.9	1.7	0.3
Hearing aid user	0.7	0.8	1.9	0.6	1.4	0.9
Tinnitus: Yes, now most or all of the time	0.7	0.8	2.2	0.9	0.5	1.5
Medication: Bendroflumethiazide	0.7	1.1	2.8	1.3	-0.0	1.7
Irritable Bowel Disease (IBD)	0.6	1.4	5.3	-2.3	-0.2	-0.3
Chronotype (morning person)	0.6	1.4	3.2	-1.2	-1.8	-0.9
Medication: Atenolol	0.6	0.7	2.4	0.5	0.5	1.6
Diabetes (self-reported)	0.6	0.9	1.9	0.7	1.4	1.1
Length of working week for main job	0.6	0.7	1.6	1.2	1.0	0.4
Ever highly irritable/argumentative for 2 days	0.6	0.7	2.5	0.1	0.5	-1.6
Birth weight	0.6	1.3	5.2	-0.2	-2.3	-0.2
Medication: Allopurinol	0.6	0.8	2.5	0.7	1.6	0.3
Medication: Seretide 50 evohaler	0.6	0.7	1.2	-0.9	-0.8	-1.1
Mean time to correctly identify matches	0.6	1.1	2.6	-1.6	-0.9	-1.0
Overall health rating	0.6	1.2	3.1	1.0	1.8	0.9
Supplements: Vitamin C	0.6	0.7	1.9	1.4	-0.4	0.8
Illnesses of father: None of the above (group 1)	0.6	0.7	1.5	-1.0	-0.6	-1.2
Supplements: Fish oil (including cod liver oil)	0.6	0.8	2.2	1.5	0.8	0.7
HDL Cholesterol	0.5	0.9	2.7	0.5	-0.7	1.7
Primary Biliary Cirrhosis	0.5	0.7	2.8	-0.2	1.7	-0.2
Triglycerides	0.5	0.8	1.7	1.1	1.3	0.6
Type 2 Diabetes (T2D) (2018)	0.5	0.9	1.8	1.0	1.4	0.8
Lung FEV1/FVC ratio	0.5	2.3	4.5	-2.0	-0.9	-2.1
Relative age of first facial hair	0.5	1.1	1.6	-1.2	-1.1	-1.2
Eye problems/disorders: Diabetes related eye disease	0.5	0.6	1.9	-0.4	-1.4	0.4
Diabetes (mother)	0.5	0.6	1.2	0.9	0.6	1.1
Medication: Levothyroxine sodium	0.5	0.9	2.3	-1.0	-1.5	-0.6
Qualifications: None of the above	0.5	1.1	2.9	1.1	1.7	0.6
Heart attack	0.5	0.6	1.7	0.5	1.3	0.8
Medication: Simvastatin	0.5	0.7	2.0	1.4	0.9	-0.3
Happiness	0.5	0.6	1.5	-1.2	-0.6	-0.6
Illnesses of mother	0.5	0.6	1.2	-0.8	0.7	-1.1
Unable to work because of sickness or disability	0.5	0.6	1.4	1.2	0.9	0.6
Alzheimer’s Disease (in mother)	0.4	0.4	0.8	-0.8	-0.9	-0.5
Alzheimer’s Disease (including proxy)	0.4	0.5	1.7	0.6	-0.0	1.3
Bipolar Disorder (2011)	0.4	0.4	0.9	-0.9	0.8	-0.5
Ulcerative Colitis	0.4	0.6	2.4	-1.5	0.1	0.3
Supplements: Zinc	0.4	0.4	1.1	1.1	0.3	0.7
Medication: Co-codamol	0.4	0.5	0.9	0.9	0.9	0.5
Hand grip strength (right)	0.4	1.0	2.6	-0.5	-1.6	-1.0
Fed-up feelings	0.4	0.7	2.6	0.2	1.6	0.4
Age when periods started (menarche)	0.4	0.9	2.0	1.0	0.8	1.4
Heel bone mineral density (BMD) T-score, automated (left)	0.4	0.8	3.2	0.1	1.8	-0.4
High blood pressure	0.4	1.2	3.7	0.9	0.3	1.9
Heel bone mineral density (BMD) T-score, automated (right)	0.4	1.0	3.5	0.5	1.9	0.3
Allergy	0.4	1.0	2.8	1.1	-0.2	1.7
Impedance of arm (right)	0.4	1.7	3.1	-1.5	-1.3	-1.7
Depression (self-reported)	0.4	0.5	0.8	-0.7	-0.8	-0.9
Medication for cholesterol, blood pressure or diabetes	0.4	0.7	1.5	-1.2	-0.6	-1.0
Hypothyroidism/myxoedema (self-reported)	0.4	0.8	1.3	-1.1	-1.1	-0.9
Chronic bronchitis/emphysema (mother)	0.4	0.5	1.3	0.7	0.5	1.1
High blood pressure (siblings)	0.4	0.6	1.5	0.7	-0.8	1.2
Commuting to job workplace: Car/motor vehicle	0.4	0.5	1.4	0.6	1.2	0.6
Forced expiratory volume in 1-second (FEV1), predicted	0.4	0.9	2.2	0.4	-1.5	1.1
Medication: Gliclazide	0.4	0.4	1.2	0.4	1.1	0.6
Mother’s age at death	0.4	0.6	1.4	-0.8	-1.2	-0.4
Medication: Atorvastatin	0.4	0.5	0.8	0.9	0.8	0.8
Ever depressed for a whole week	0.4	0.5	1.6	0.5	1.3	0.2
Deep venous thrombosis (DVT) (self-reported)	0.4	0.5	0.8	0.8	0.8	0.9
Arm predicted mass (left)	0.4	1.9	4.8	1.5	0.5	2.2
Age at First Birth	0.3	0.5	0.7	-0.9	-0.7	-0.8
Crohns Disease (2012)	0.3	0.5	1.6	-0.7	1.3	0.1
HbA1C	0.3	0.3	0.9	0.6	-0.3	0.9
Lupus	0.3	0.5	0.9	0.9	0.9	0.5
Blood Eosinophil Count	0.3	2.5	4.0	2.0	2.0	1.5
Blood Red Count	0.3	3.0	9.2	-1.1	-3.0	-1.3
Heel T-Score	0.3	2.8	6.4	1.4	2.5	1.6
Systolic blood pressure, automated reading	0.3	0.8	2.9	-0.1	-1.7	0.6
Severe depression (siblings)	0.3	0.3	0.6	0.7	-0.1	0.8
Leg fat-free mass (left)	0.3	1.7	4.7	1.4	0.1	2.2
Frequency of unenthusiasm / disinterest in last 2 weeks	0.3	0.5	1.3	-1.1	-0.6	-0.4
Stomach or abdominal pain in last month	0.3	0.4	0.6	-0.8	-0.6	-0.8
Supplements: Glucosamine	0.3	0.5	1.1	0.8	-0.2	1.1
Sitting height	0.3	2.4	8.0	-1.3	-2.8	-0.4
Leg predicted mass (left)	0.3	1.8	4.8	1.5	0.2	2.2
Pain all over the body in last month	0.3	0.3	0.8	-0.3	-0.9	0.5
Time employed in main current job	0.3	0.3	0.8	0.9	-0.1	0.6
Hair/balding pattern: Pattern 3	0.3	0.4	0.7	-0.8	-0.7	-0.8
Serious illness, injury or assault of a close relative in last 2 years	0.3	0.4	0.9	-1.0	-0.7	-0.4
Impedance of arm (left)	0.3	1.5	3.0	-1.2	-1.2	-1.7
Birth weight of first child	0.3	0.6	2.4	0.1	-1.5	0.0
Blood clot in the leg (DVT)	0.3	0.4	0.7	0.6	0.8	0.8
Gout (self-reported)	0.3	0.5	1.2	-0.5	1.1	-0.6
Arm fat-free mass (right)	0.3	1.8	4.7	1.5	0.5	2.2
Qualifications: College or University degree	0.3	0.9	3.3	-0.4	-1.8	-0.3
Arm predicted mass (right)	0.3	1.7	4.8	1.4	0.2	2.2
Hypertension (Self-reported)	0.3	0.8	2.5	0.8	-0.1	1.6
Ever had stillbirth, spontaneous miscarriage or termination	0.3	0.3	0.9	-0.7	0.1	-0.9
Mouth/teeth dental problems: Mouth ulcers	0.3	0.5	1.6	0.5	1.3	-0.2
Medication: Blood pressure	0.3	0.6	0.9	0.9	0.9	0.9
Basal metabolic rate	0.3	1.6	4.6	1.4	0.1	2.1
Arm fat-free mass (left)	0.3	1.5	4.2	1.3	0.3	2.0
Diastolic blood pressure, automated reading	0.3	1.0	2.1	-1.1	-1.4	-0.9
Heart attack/myocardial infarction (self-reported)	0.3	0.3	1.2	0.1	1.1	0.3
Heart disease (siblings)	0.3	0.4	0.9	0.9	-0.0	0.7
Schizophrenia (2018)	0.2	0.5	1.2	0.9	-0.2	1.1
Crohns Disease (2017)	0.2	0.4	0.6	-0.8	0.7	0.7
Fasting Glucose	0.2	0.3	0.8	0.5	0.1	0.9
Height	0.2	4.2	7.8	1.6	-2.5	2.8
Systolic Blood Pressure	0.2	0.9	3.4	0.2	-1.8	0.4
Hair Pigment	0.2	6.1	14.7	-3.8	-2.7	-1.6
Angina	0.2	0.2	0.4	0.6	0.6	0.4
Vitamin and mineral supplements	0.2	0.2	0.7	-0.1	0.8	-0.4
Average weekly fortified wine intake	0.2	0.2	0.6	0.6	0.8	0.1
Relative age voice broke	0.2	0.3	0.9	-0.3	-1.0	-0.1
High blood pressure (mother)	0.2	0.3	1.0	-0.4	-1.0	-0.4
Trunk fat-free mass	0.2	0.9	1.8	0.4	-1.3	1.3
Frequency of tiredness / lethargy in last 2 weeks	0.2	0.4	0.9	-0.6	0.9	-0.6
Falls in the last year	0.2	0.3	0.5	0.6	0.6	0.7
Medication: Cholesterol lowering	0.2	0.3	0.5	0.7	0.7	-0.0
Trunk predicted mass	0.2	0.9	1.7	0.4	-1.3	1.3
Standing height	0.2	2.2	8.1	-0.5	-2.9	0.6
Breastfed as a baby	0.2	0.3	0.9	0.1	-0.4	1.0
Loud music exposure frequency	0.2	0.2	0.6	0.8	-0.3	0.4
Medication: Amlodipine	0.2	0.3	0.5	-0.6	0.7	-0.6
Medication: Ventolin 100micrograms inhaler	0.2	0.2	0.4	-0.7	-0.6	0.0
Angina (self-reported)	0.2	0.3	0.5	0.6	0.7	0.4
Comparative height size at age 10	0.2	0.9	3.3	-0.5	-1.8	0.0
Chest pain or discomfort	0.2	0.3	1.1	0.4	1.1	0.0
Family relationship satisfaction	0.2	0.2	0.6	-0.8	-0.4	-0.4
Qualifications: NVQ or HND or HNC or equivalent	0.2	0.3	0.7	-0.5	0.3	0.8
Illnesses of siblings: Diabetes	0.2	0.2	0.3	0.6	0.5	0.5
Whole body fat-free mass	0.2	1.2	3.5	1.0	-0.7	1.9
Leg fat-free mass (right)	0.2	1.1	3.5	1.0	-0.2	1.9
Mineral and other dietary supplements	0.2	0.3	0.9	-0.9	-0.4	-0.4
Osteoporosis (self-reported)	0.2	0.3	0.5	-0.7	-0.6	-0.5
Whole body water mass	0.2	1.0	2.9	0.8	-0.7	1.7
Leg predicted mass (right)	0.2	1.3	4.0	1.1	-0.2	2.0
Miserableness	0.2	0.4	1.3	-0.5	1.2	-0.2
Wears glasses or contact lenses	0.2	0.3	0.6	0.6	0.8	0.2
Ever had prostate specific antigen (PSA) test	0.2	0.2	0.5	0.7	0.6	-0.0
Basal cell carcinoma (self-reported)	0.2	0.3	0.6	0.8	-0.3	0.7
Bipolar Disorder (2018)	0.1	0.2	0.7	-0.8	0.4	-0.3
Verbal and Numeric Reasoning (VNR)	0.1	0.2	0.5	-0.5	-0.7	0.1
Breast Cancer	0.1	0.2	0.6	-0.8	0.5	-0.2
Ovarian Cancer	0.1	0.1	0.2	-0.2	-0.3	-0.4
Rheumatoid Arthritis	0.1	0.2	0.7	0.1	-0.9	0.1
Schizophrenia (2014)	0.1	0.3	0.7	0.4	-0.5	0.9
Blood White Count	0.1	0.6	1.5	1.2	0.8	0.6
Waist Hip Ratio (WHR)	0.1	0.3	0.9	0.4	0.4	-1.0
Respiratory disease	0.1	0.3	0.7	0.4	-0.8	0.6
Tanning	0.1	0.7	1.3	0.8	-1.1	1.0
Ever had hysterectomy (womb removed)	0.1	0.1	0.1	-0.4	0.2	-0.2
Diabetes (father)	0.1	0.1	0.2	-0.4	0.3	0.4
Pack years adult smoking proportion	0.1	0.1	0.4	-0.2	0.6	-0.2
Impedance of leg (right)	0.1	0.4	1.2	0.5	1.1	-0.4
Impedance of leg (left)	0.1	0.4	1.1	0.3	1.0	-0.6
Hearing difficulty/problems with background noise	0.1	0.1	0.4	0.2	-0.6	-0.2
Ever unenthusiastic/disinterested for a whole week	0.1	0.2	0.6	-0.3	-0.1	-0.8
Illnesses of siblings	0.1	0.2	0.5	-0.0	0.7	-0.5
Lung cancer (father)	0.1	0.1	0.1	-0.3	0.3	-0.1
Headache pain in last month	0.1	0.1	0.5	0.2	0.7	0.0
Glaucoma (self-reported)	0.1	0.1	0.3	0.6	-0.1	-0.2
Comparative body size at age 10	0.1	0.3	1.0	0.2	1.0	0.3
Seen a psychiatrist for nerves, anxiety, tension or depression	0.1	0.1	0.2	0.5	0.2	0.2
Wheeze or whistling in the chest in last year	0.1	0.2	0.3	-0.6	-0.2	0.5
Health satisfaction	0.1	0.1	0.2	-0.0	0.5	-0.2
Mouth/teeth dental problems: Loose teeth	0.1	0.1	0.3	-0.5	0.2	0.4
Neck or shoulder pain in last month	0.1	0.1	0.2	0.5	0.4	-0.3
Heart disease (mother)	0.1	0.1	0.2	0.5	-0.4	0.2
Pulse rate, automated reading	0.1	0.2	0.4	0.5	-0.6	-0.2
Alcohol intake frequency.	0.1	0.3	0.9	0.3	0.9	0.4
Handedness (chirality/laterality): Left-handed	0.1	0.1	0.2	0.2	-0.1	0.4
Ever had bowel cancer screening	0.1	0.2	0.6	0.2	0.2	-0.8
Eye problems/disorders: Cataract	0.1	0.1	0.2	-0.1	0.4	0.4
Breast cancer (self-reported)	0.1	0.1	0.2	0.2	0.5	-0.3
Asthma (self-reported)	0.1	0.1	0.3	-0.1	-0.6	-0.2
High cholesterol (Self-reported)	0.1	0.2	0.5	0.1	0.5	-0.7
Myopia	0.1	0.1	0.2	-0.4	-0.5	0.0
Impedance of whole body	0.1	0.5	1.5	-0.5	0.0	-1.2
Bipolar Disorder or Schizophrenia	0.0	0.1	0.4	0.2	0.1	0.7
Depressed Affect (Nagel 2018)	0.0	0.1	0.2	-0.5	-0.2	0.3
Intelligence (Savage-Jansen 2018)	0.0	0.1	0.3	-0.3	-0.6	-0.2
Prostate Cancer	0.0	0.0	0.0	0.0	0.0	0.0
Body Mass Index (BMI) (2010)	0.0	0.0	0.1	0.2	-0.2	0.2
Blood Platelet Count	0.0	0.4	0.9	0.7	-1.0	0.6
Cardiovascular Disease	0.0	0.1	0.3	0.3	0.4	0.5
Hearing difficulty/problems: Yes	0.0	0.1	0.1	0.3	-0.4	-0.1
Number of incorrect matches in round	0.0	0.1	0.2	-0.3	-0.1	-0.4
Hair/balding pattern: Pattern 2	0.0	0.0	0.1	0.0	-0.3	-0.3
Pulse rate	0.0	0.1	0.2	0.1	-0.4	-0.2
Asthma	0.0	0.1	0.3	-0.0	-0.6	-0.1
Prospective memory result	0.0	0.1	0.2	0.4	0.2	0.0
Leg pain on walking	0.0	0.1	0.1	0.2	0.3	0.2
Illnesses of father: Heart disease	0.0	0.1	0.1	0.3	0.3	-0.2
Mood swings	0.0	0.0	0.0	0.0	0.1	0.1
Eye problems/disorders: Glaucoma	0.0	0.1	0.2	0.0	0.4	-0.2
Medication: Lisinopril	0.0	0.0	0.1	0.3	-0.3	0.2
Irritability	0.0	0.1	0.2	0.2	-0.0	0.4
Pack years of smoking	0.0	0.1	0.1	-0.3	0.3	-0.3

Hub : Genes

REV3L

Models

Trait associations