Best TWAS P=1.12e-10 · Best GWAS P=1.58e-09 conditioned to 0.501
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | The Cancer Genome Atlas | Lung Adenocarcinoma | FAM108C1 | 0.05 | 0.04 | lasso | 3 | 0.04 | 5.6e-06 | 6.0 | -5.9 | 4.2e-09 | -1.00 | 0.00 | 1.0 | FALSE |
2 | The Cancer Genome Atlas | Prostate Adenocarcinoma | FAM108C1 | 0.07 | 0.02 | lasso | 2 | 0.02 | 1.7e-03 | -5.6 | -6.4 | 1.1e-10 | -0.89 | 0.01 | 0.9 | TRUE |