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chr11:60,839,578-62,290,719

Best TWAS P=1.07e-08 · Best GWAS P=1.11e-08 conditioned to 1

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
3	GTEx	Artery Tibial	TMEM258	0.08	0.05	lasso	5	0.02	1.1e-02	5.7	5.7	1.1e-08	0.98	0.01	0.99	TRUE
1	CommonMind	Brain Pre-frontal Cortex	FADS1	0.14	0.16	lasso	2	0.16	7.2e-19	5.7	-5.7	1.5e-08	-0.97	0.01	0.99	FALSE
2	CommonMind	Brain Pre-frontal Cortex	FEN1	0.07	0.06	lasso	4	0.06	1.1e-07	5.7	5.7	1.5e-08	0.97	0.01	0.99	FALSE
5	ROSMAP	Brain Pre-frontal Cortex	TMEM258	0.14	0.16	lasso	4	0.15	4.7e-19	5.5	5.5	3.3e-08	0.93	0.02	0.98	FALSE
4	NTR	Blood	C11orf10	0.06	0.08	bslmm	399	0.08	1.3e-24	5.5	5.5	5.1e-08	0.91	0.02	0.98	FALSE
7	The Cancer Genome Atlas	Thyroid Carcinoma	C11orf10	0.02	0.02	blup	44	0.02	1.8e-03	5.0	5.4	7.6e-08	0.95	0.02	0.73	FALSE
6	ROSMAP	Brain Pre-frontal Cortex	FADS1	0.08	0.08	enet	10	0.09	1.5e-11	5.7	-5.4	8.4e-08	-0.96	0.01	0.99	FALSE