TWAS hub - C11orf10

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	NTR	Blood	0.0639	0.0140	0.0000	0.082	0.072	0.078	0.08	0.080	3.0e-25	3.8e-22	6.4e-24	1.3e-24	1.6e-24
2	TCGA	Prostate Adenocarcinoma	0.0207	0.0136	0.0086	0.009	0.007	0.013	NA	0.005	3.7e-02	5.2e-02	1.6e-02	NA	8.4e-02
3	TCGA	Thyroid Carcinoma	0.0190	0.0120	0.0090	0.019	0.024	0.021	NA	0.021	4.9e-03	1.8e-03	3.8e-03	NA	3.5e-03

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3
LDL Cholesterol	48.3	76.4	87.2	-9.1	-7.7	-9.3
Triglycerides	41.2	67.5	88.9	9.4	5.0	9.4
HDL Cholesterol	38.6	64.4	82.8	-9.1	-5.5	-9.0
Pulse rate, automated reading	38.4	124.0	153.8	12.4	8.5	12.1
Blood Platelet Count	32.1	372.7	458.0	21.4	14.8	21.0
Fasting Glucose	23.6	28.3	39.4	-5.7	-3.5	-6.3
Blood Red Count	22.5	217.7	269.0	15.5	12.0	16.4
Pulse rate	22.0	37.0	46.9	6.8	4.2	6.8
Average weekly champagne plus white wine intake	20.2	27.8	29.7	5.5	5.0	5.4
Respiratory disease	17.2	38.2	47.7	-6.8	-4.5	-6.9
Asthma (self-reported)	15.6	31.1	39.3	-6.3	-3.9	-6.2
Hypothyroidism (self reported)	15.5	35.6	43.7	-6.6	-4.8	-6.4
Asthma	14.5	28.7	36.7	-6.1	-3.8	-5.9
Blood Eosinophil Count	13.9	106.8	136.9	-10.5	-8.6	-11.7
Medication: Levothyroxine sodium	13.8	23.3	27.1	-5.0	-4.2	-5.2
Number of live births	13.2	18.7	23.8	-4.7	-3.2	-4.9
Hypothyroidism/myxoedema (self-reported)	11.6	22.6	25.9	-5.1	-4.3	-4.8
Bipolar Disorder (2018)	11.1	17.5	19.7	3.6	4.4	4.4
Bipolar Disorder (2011)	10.5	10.2	13.8	2.6	3.1	3.7
Supplements: Fish oil (including cod liver oil)	10.5	13.7	17.3	-3.8	-3.0	-4.2
Hair/balding pattern: Pattern 4	10.3	25.0	30.2	-5.3	-4.1	-5.5
Myopia	10.2	14.8	15.6	3.9	3.8	3.8
Crohns Disease (2012)	10.0	16.1	19.9	4.5	3.0	4.4
Seen a psychiatrist for nerves, anxiety, tension or depression	10.0	13.0	16.1	3.0	3.7	4.0
Medication: Simvastatin	9.9	14.6	16.2	-3.6	-4.0	-3.9
Number of treatments/medications taken	9.7	17.4	18.7	-4.1	-4.1	-4.3
Exposure to tobacco smoke at home	9.7	10.9	11.6	-3.4	-3.1	-3.4
Blood White Count	9.5	70.7	92.0	-8.1	-7.4	-9.6
Irritability	9.5	16.1	22.7	4.1	3.0	4.8
Ever unenthusiastic/disinterested for a whole week	8.7	10.6	10.9	3.3	3.2	3.3
Wheeze or whistling in the chest in last year	8.5	15.2	20.0	-3.8	-3.3	-4.5
Heel bone mineral density (BMD) T-score, automated (right)	8.4	19.2	28.3	4.2	3.4	5.3
Family relationship satisfaction	8.3	10.2	10.7	3.3	3.2	3.1
High cholesterol (Self-reported)	7.8	13.9	16.1	-3.3	-3.8	-4.0
Crohns Disease (2017)	7.7	16.9	24.9	5.0	2.6	4.4
Commuting to job workplace: Car/motor vehicle	7.7	8.8	8.8	-3.0	-3.0	-3.0
Verbal and Numeric Reasoning (VNR)	7.6	18.2	20.0	4.0	4.3	4.5
Mineral and other dietary supplements	7.6	10.2	12.5	3.4	2.6	3.5
Blood clot in the leg (DVT)	7.2	9.3	13.8	-2.7	-2.6	-3.7
Fluid intelligence score	7.1	14.7	16.2	4.0	3.6	3.9
Heel T-Score	7.0	55.9	67.6	8.1	5.8	8.2
Cholesterol lowering medication	6.9	10.1	12.7	-3.0	-3.0	-3.6
Schizophrenia vs Biploar Disorder	6.8	9.0	14.4	-2.8	-2.1	-3.8
Type 2 Diabetes (T2D) (2012)	6.7	7.7	10.9	-3.3	-1.6	-3.1
Taking other prescription medications	6.7	10.3	13.0	-3.3	-2.6	-3.6
Qualifications: NVQ or HND or HNC or equivalent	6.7	8.0	12.2	-2.8	-2.1	-3.5
Deep venous thrombosis (DVT) (self-reported)	6.6	8.5	13.0	-2.5	-2.5	-3.6
Medication: Laxatives (e.g. Dulcolax, Senokot)	6.4	7.5	8.8	-2.5	-3.0	-2.7
Heel bone mineral density (BMD) T-score, automated (left)	6.3	14.3	20.7	3.5	3.2	4.5
Long-standing illness, disability or infirmity	6.3	9.7	11.5	-3.4	-2.5	-3.4
Rheumatoid Arthritis	6.1	8.4	10.1	-3.0	-2.4	-3.2
Hearing aid user	6.1	6.9	8.7	-2.3	-2.6	-2.9
Intelligence (Savage-Jansen 2018)	5.7	17.6	18.9	4.3	4.0	4.3
Fractured/broken bones in last 5 years	5.7	7.4	11.1	-2.9	-1.5	-3.3
Heart attack/myocardial infarction (self-reported)	5.7	7.3	9.4	-2.7	-2.3	-3.1
Allergy	5.6	12.8	17.6	4.1	2.0	4.2
Medication: Ibuprofen	5.6	6.7	8.9	-2.4	-2.4	-3.0
Bipolar Disorder or Schizophrenia	5.5	13.4	16.2	3.2	3.7	4.0
Forced expiratory volume in 1-second (FEV1), predicted	5.5	11.5	14.4	-3.4	-2.9	-3.8
Number of self-reported non-cancer illnesses	5.5	9.5	11.3	-3.2	-2.6	-3.4
Vitamin and mineral supplements	5.4	7.3	10.0	3.2	1.6	3.1
Falls in the last year	5.4	7.3	9.5	-3.0	-1.8	-3.1
Number of children fathered	5.3	6.0	7.8	-2.4	-2.8	-2.1
Townsend deprivation index at recruitment	5.1	7.1	9.4	2.3	2.6	3.1
Medication for pain relief, constipation, heartburn	5.0	8.6	10.9	2.6	2.9	3.3
Mouth/teeth dental problems: Mouth ulcers	5.0	7.9	10.6	2.3	3.3	2.8
Commuting to job workplace: Public transport	5.0	6.0	7.2	2.0	2.7	2.6
Osteoporosis (self-reported)	4.9	6.0	7.4	-2.7	-2.1	-2.5
Heart attack	4.7	6.0	7.7	-2.4	-2.1	-2.8
Seen doctor (GP) for nerves, anxiety, tension or depression	4.7	7.2	9.1	2.3	2.7	3.0
Average weekly spirits intake	4.5	5.5	6.2	-2.5	-2.0	-2.5
Medication: Ibuprofen (e.g. Nurofen)	4.5	5.7	7.5	-2.4	-2.0	-2.7
Irritable Bowel Disease (IBD)	4.3	10.2	14.3	3.8	1.7	3.7
Other serious medical condition/disability diagnosed by doctor	4.3	5.6	7.6	-2.3	-2.0	-2.8
Mouth/teeth dental problems: Bleeding gums	4.3	5.5	5.8	2.3	2.3	2.4
Standing height	4.2	41.2	48.6	-7.0	-5.3	-6.9
Headache pain in last month	4.2	7.3	10.3	-3.2	-1.2	-3.2
Medication: Seretide 50 evohaler	4.2	4.8	6.7	-2.6	-1.7	-2.2
Ever depressed for a whole week	4.2	5.2	7.5	2.1	1.8	2.7
Maternal smoking around birth	4.1	6.0	6.9	-2.4	-2.6	-2.3
Medication: Allopurinol	4.0	5.3	6.9	2.6	1.6	2.6
Major Depression (MDD)	3.7	4.5	8.0	2.4	0.0	2.8
Had other major operations	3.7	4.5	5.2	2.1	2.0	2.3
Miserableness	3.7	6.3	10.8	2.5	1.5	3.3
Hair/balding pattern: Pattern 3	3.5	5.2	6.7	-2.6	-2.1	-2.1
Medication: Paracetamol	3.4	5.2	6.7	-2.1	-2.2	-2.6
Height	3.3	64.4	81.4	-8.6	-6.2	-9.0
Medication: Paracetamol	3.3	5.4	6.4	-2.1	-2.3	-2.5
Had major operations	3.2	3.8	4.6	2.1	1.6	2.1
Tinnitus: Yes, but not now, but have in the past	3.1	3.3	5.3	-2.3	-0.9	-1.9
Sitting height	3.1	21.8	24.2	-4.9	-4.5	-4.6
Basal cell carcinoma (self-reported)	3.1	3.7	5.7	-1.9	-1.4	-2.4
Medication for hormone replacement therapy	3.0	3.3	3.4	-1.8	-1.8	-1.8
Medication: Ventolin 100micrograms inhaler	2.9	3.7	5.9	-2.4	-1.4	-1.8
Schizophrenia (2014)	2.8	6.3	7.7	2.2	2.4	2.8
Chronotype (morning person)	2.8	6.4	8.9	-3.0	-1.9	-2.6
Worry too long after embarrassment	2.8	4.7	8.5	-2.9	-1.4	-1.9
Wears glasses or contact lenses	2.8	3.2	3.6	1.9	1.7	1.7
Multivitamins +/- minerals	2.7	3.4	5.2	-2.2	-0.3	-2.3
Medication: Cholesterol lowering	2.7	4.2	4.6	-2.1	-2.1	-1.9
Exposure to tobacco smoke outside home	2.7	3.6	5.7	-1.7	-1.5	-2.4
Leg pain on walking	2.7	3.4	5.6	-1.4	-2.4	-1.7
Diastolic blood pressure, automated reading	2.7	8.4	13.3	3.6	1.6	3.1
Supplements: Calcium	2.7	3.0	3.4	-1.9	-1.6	-1.8
Qualifications: CSEs or equivalent	2.6	3.4	4.0	-1.8	-2.0	-1.8
Gout (self-reported)	2.6	3.6	5.4	2.3	0.8	2.2
Medication for cholesterol	2.6	3.9	4.5	2.1	1.7	2.1
Pulse wave reflection index	2.5	3.1	3.5	-1.7	-1.8	-1.9
Medication: Lisinopril	2.5	3.2	4.8	1.2	1.8	2.2
Age at First Birth	2.4	3.5	4.0	1.6	2.0	2.0
Leg fat percentage (right)	2.3	8.2	11.6	3.3	1.4	3.4
Medication: Aspirin	2.3	3.1	3.6	-1.8	-1.9	-1.6
HbA1C	2.2	2.4	3.7	-1.7	-0.8	-1.9
Mouth/teeth dental problems	2.2	3.4	4.8	-2.2	-1.6	-1.7
Waist Hip Ratio (WHR)	2.1	9.6	11.7	-2.9	-3.4	-3.0
Type 2 Diabetes (T2D) (2018)	2.1	4.0	5.5	-1.7	-2.3	-1.9
Ever highly irritable/argumentative for 2 days	2.1	2.5	4.1	1.6	0.8	2.0
Shortness of breath walking on level ground	2.1	2.5	3.8	-1.0	-1.9	-1.6
Mouth/teeth dental problems: Loose teeth	2.1	2.5	3.0	1.7	1.7	1.3
Eye problems/disorders: Cataract	2.1	2.4	2.7	-1.6	-1.4	-1.6
Lupus	2.0	3.1	4.9	-2.2	-1.1	-1.8
Forced expiratory volume in 1-second (FEV1)	2.0	6.9	11.0	-3.3	-0.6	-3.0
Medication: Aspirin	1.9	2.6	3.5	-1.6	-1.9	-1.3
Ulcerative Colitis	1.8	2.6	4.2	1.9	0.2	2.0
Supplements: Glucosamine	1.8	2.3	2.8	-1.7	-1.2	-1.6
Prospective memory result	1.8	2.2	2.5	-1.3	-1.6	-1.5
Leg fat percentage (left)	1.8	6.5	9.6	3.0	1.0	3.1
Ovarian Cancer	1.7	2.3	4.6	-0.8	-1.2	-2.2
Happiness	1.7	2.1	2.9	1.3	1.7	1.3
Commuting to job workplace: Cycle	1.7	2.1	3.0	1.7	1.2	1.4
Body mass index (BMI)	1.6	7.0	10.8	3.3	1.0	3.0
Arm fat percentage (right)	1.5	6.0	9.7	3.1	0.9	2.8
Comparative height size at age 10	1.5	8.2	10.6	-3.1	-2.1	-3.2
Allergy or Eczema	1.4	3.8	5.4	-2.3	-0.8	-2.3
Stomach or abdominal pain in last month	1.4	1.7	1.9	-1.3	-1.4	-1.3
Father’s age at death	1.4	1.9	2.5	1.6	0.9	1.6
Illness, injury, bereavement, stress in last 2 years	1.4	1.7	2.6	1.5	0.3	1.6
Lung FVC	1.3	6.8	12.0	1.8	3.5	2.3
Ever used hormone-replacement therapy (HRT)	1.3	1.7	2.6	-1.6	-1.0	-1.2
Frequency of unenthusiasm / disinterest in last 2 weeks	1.3	1.7	2.4	1.6	0.7	1.5
Past tobacco smoking	1.3	2.5	2.9	1.3	1.7	1.7
Medication: Ramipril	1.3	1.6	2.3	1.5	0.7	1.5
Mean time to correctly identify matches	1.3	2.4	3.6	1.4	1.9	1.3
Sensitivity / hurt feelings	1.2	2.0	3.0	-1.7	-1.3	-1.1
Forced vital capacity (FVC)	1.2	4.5	7.3	-2.7	-0.2	-2.5
Hayfever/allergic rhinitis (self-reported)	1.2	1.5	2.9	-1.3	-0.0	-1.7
Tense / ‘highly strung’	1.2	1.9	3.9	0.4	2.0	1.3
Qualifications: O levels/GCSEs or equivalent	1.2	1.9	2.8	0.9	1.7	1.4
Eye problems/disorders: None of the above	1.2	1.4	1.9	1.3	0.9	1.4
Overall health rating	1.2	2.6	3.8	-1.3	-1.5	-1.9
Serious illness, injury or assault to yourself	1.1	1.3	2.1	-1.2	-0.5	-1.5
Qualifications: College or University degree	1.1	3.4	9.0	-0.2	3.0	1.1
Qualifications: nursing, teaching	1.1	1.6	4.1	0.5	2.0	0.8
Alzheimer’s Disease (in father)	1.0	1.0	1.6	0.5	1.3	1.1
Ulcerative Colitis (UC)	1.0	1.8	3.3	1.3	0.7	1.8
Lung FEV1/FVC ratio	1.0	5.2	8.9	-3.0	-0.8	-2.5
Hair Pigment	1.0	27.6	30.7	5.4	5.5	4.7
Frequency of depressed mood in last 2 weeks	1.0	1.3	1.6	1.0	1.2	1.3
Medication: Atenolol	1.0	1.2	1.7	0.8	1.1	1.3
Arm fat percentage (left)	1.0	3.8	6.5	2.5	0.4	2.2
Diabetes diagnosed by doctor	1.0	1.6	3.5	-0.5	-1.9	-1.0
Medication: Gliclazide	1.0	1.1	3.2	-0.2	-1.8	-0.4
Pain type(s) experienced in last month: Hip pain	1.0	1.3	1.6	-1.1	-1.1	-1.3
Hayfever, allergic rhinitis or eczema	0.9	2.0	3.0	-1.7	-0.5	-1.7
Trunk fat-free mass	0.9	5.4	6.0	-2.4	-2.1	-2.4
Depression (self-reported)	0.9	1.1	2.6	0.8	-0.3	1.6
Forced expiratory volume in 1-second (FEV1), Best measure	0.9	3.0	4.9	-2.2	0.3	-2.0
Trunk predicted mass	0.9	5.0	5.8	-2.4	-2.0	-2.3
Supplements: Vitamin C	0.9	1.0	2.2	-1.5	-0.1	-0.9
Mother’s age at death	0.9	1.2	2.2	1.1	0.5	1.5
Illnesses of father: High blood pressure	0.9	1.2	1.8	-1.3	-0.2	-1.4
Unable to work because of sickness or disability	0.9	1.2	3.2	0.1	-1.8	-0.5
Medication: Omeprazole (e.g. Zanprol)	0.9	1.0	1.7	1.3	0.9	0.8
Relative age of first facial hair	0.8	1.7	2.1	1.3	1.2	1.5
High blood pressure	0.8	2.1	2.8	1.7	1.1	1.5
Chronic bronchitis/emphysema (father)	0.8	1.0	1.4	-0.8	-1.0	-1.2
Impedance of arm (left)	0.8	3.7	5.5	-1.9	-1.4	-2.4
Body fat percentage	0.8	3.2	5.2	2.3	0.1	2.1
Arm predicted mass (right)	0.8	4.2	5.1	-2.0	-2.3	-1.9
Illnesses of father: Heart disease	0.8	1.1	1.5	-1.2	-0.8	-1.1
Leg fat-free mass (right)	0.8	4.0	5.3	-1.6	-2.3	-2.1
Leg predicted mass (right)	0.8	4.1	5.5	-1.6	-2.3	-2.1
Ever smoked	0.8	1.4	2.1	-0.7	-1.4	-1.3
Schizophrenia (2018)	0.7	1.5	2.6	1.1	1.0	1.6
Angina	0.7	1.0	1.4	-1.2	-0.8	-0.9
Fed-up feelings	0.7	1.2	1.7	1.0	-1.0	1.3
High blood pressure (mother)	0.7	1.0	1.1	-1.0	-1.0	-1.0
Alcohol usually taken with meals	0.7	1.1	2.2	0.0	1.5	1.0
Diabetes (self-reported)	0.7	1.1	2.9	-0.1	-1.7	-0.7
Alcohol intake versus 10 years previously	0.7	1.1	2.4	-0.6	-1.6	-0.6
Frequency of tiredness / lethargy in last 2 weeks	0.7	1.1	3.0	-0.2	-1.7	-0.5
Noisy workplace	0.7	0.8	1.1	-0.8	-1.0	-0.9
Illnesses of mother	0.7	0.9	1.8	0.7	1.4	0.6
Length of working week for main job	0.7	0.8	1.3	-1.0	-0.4	-1.1
Medication: Amlodipine	0.7	1.0	1.6	0.6	1.3	0.9
Leg fat mass (right)	0.7	2.9	4.3	2.1	0.5	2.0
Smoking status: Previous	0.7	1.0	1.1	-1.0	-0.9	-1.1
Whole body fat-free mass	0.7	4.0	4.5	-1.9	-2.1	-2.0
Commuting to job workplace: Walk	0.7	0.7	1.0	0.9	0.6	1.0
Whole body water mass	0.7	3.8	4.2	-1.8	-2.0	-2.0
Financial situation satisfaction	0.7	0.8	1.2	-1.1	-0.7	-0.9
Cardiovascular Disease	0.6	2.0	2.5	-1.2	-1.6	-1.4
Arm fat mass (right)	0.6	2.6	4.4	2.1	0.2	1.8
Arm fat-free mass (right)	0.6	3.2	4.2	-1.7	-2.1	-1.6
Angina (self-reported)	0.6	0.8	1.2	-1.1	-0.8	-0.8
Medication: Omeprazole	0.6	0.7	1.3	1.1	0.5	0.8
Knee pain experienced in last month	0.6	1.0	1.4	-0.7	-1.1	-1.2
Vascular/heart problems diagnosed by doctor	0.6	1.6	2.0	-1.4	-1.0	-1.4
Impedance of whole body	0.6	3.2	4.4	-2.1	-1.2	-2.0
Leg fat mass (left)	0.6	2.5	3.8	1.9	0.3	1.9
Depression (Nagel 2018)	0.5	0.7	1.0	0.8	0.7	1.0
Alzheimer’s Disease (in mother)	0.5	0.6	0.7	-0.8	-0.8	-0.7
Reaction Time	0.5	1.0	2.6	0.6	1.6	0.3
Diabetes (father)	0.5	0.7	1.0	-1.0	-0.7	-0.7
Diabetes (mother)	0.5	0.7	1.1	-0.8	-0.4	-1.0
Leg fat-free mass (left)	0.5	2.7	4.2	-1.2	-2.0	-1.7
Current tobacco smoking	0.5	0.8	1.5	1.2	-0.9	-0.2
Leg predicted mass (left)	0.5	2.8	4.2	-1.2	-2.0	-1.7
Frequency of tenseness / restlessness in last 2 weeks	0.5	0.9	1.3	0.3	1.1	1.1
Hearing difficulty/problems with background noise	0.5	0.8	2.0	0.5	-1.4	0.4
Qualifications: None of the above	0.5	1.1	2.9	-0.1	-1.7	-0.7
Medication for cholesterol, blood pressure or diabetes	0.5	0.9	1.3	1.1	1.1	0.6
Birth weight	0.5	1.0	1.9	1.4	0.3	1.0
Forced vital capacity (FVC), Best measure	0.5	1.8	2.4	-1.6	0.8	-1.5
Chest pain or discomfort	0.5	0.8	1.4	-1.2	-0.3	-0.9
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.5	0.5	1.1	0.6	1.0	0.4
Arm fat mass (left)	0.5	2.0	3.3	1.8	0.1	1.6
Ever taken oral contraceptive pill	0.5	0.5	0.7	-0.9	0.2	-0.9
Basal metabolic rate	0.5	2.9	4.0	-1.4	-2.0	-1.6
Alcohol drinker status: Previous	0.5	0.6	0.8	0.6	0.9	0.7
Depressed Affect (Nagel 2018)	0.4	0.8	1.6	0.8	-0.5	1.3
Breast Cancer	0.4	0.9	2.5	1.6	0.1	0.6
Prostate Cancer	0.4	0.5	1.1	-0.1	1.1	0.6
Mean Putamen Volume	0.4	0.5	1.0	1.0	0.1	0.6
Neuroticism	0.4	1.1	2.1	0.8	0.7	1.4
Tanning	0.4	4.3	6.6	-2.6	-1.4	-2.1
Medication: Co-codamol	0.4	0.4	0.7	-0.8	-0.5	-0.5
Medication: Metformin	0.4	0.6	1.5	1.2	-0.3	0.5
Trunk fat percentage	0.4	1.5	2.2	1.5	-0.8	1.3
Neuroticism score	0.4	0.8	1.9	0.6	0.2	1.4
Mouth/teeth dental problems: Dentures	0.4	0.6	1.2	0.3	-1.1	-0.8
Birth weight of first child	0.4	0.7	1.8	0.3	-1.4	0.3
Peak expiratory flow (PEF)	0.4	1.0	2.3	-1.5	-0.4	-0.7
Number of full brothers	0.4	0.5	0.6	0.7	0.8	0.6
Reason for reducing amount of alcohol drunk: Health precaution	0.4	0.4	1.1	-0.2	0.4	1.0
Pulse wave peak to peak time	0.4	0.5	1.1	-1.0	0.1	-0.7
Emphysema/chronic bronchitis	0.4	0.5	0.9	-1.0	-0.4	-0.6
Neck or shoulder pain in last month	0.4	0.6	1.3	-1.1	-0.4	-0.6
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.4	0.5	1.4	0.2	-1.2	0.3
Hypertension (Self-reported)	0.4	1.0	1.2	1.1	0.8	1.1
Ever had bowel cancer screening	0.4	0.4	0.8	-0.5	-0.9	-0.5
Back pain experienced in last month	0.4	0.5	0.9	-0.6	-0.6	-1.0
Smoking status: Current	0.4	0.6	0.9	0.9	-1.0	-0.4
Medication: Blood pressure	0.4	0.8	1.0	0.9	1.0	0.7
Pack years of smoking	0.4	0.7	1.4	1.2	0.4	0.6
Neuroticism (2016)	0.3	0.4	0.8	0.6	-0.3	0.9
BMI	0.3	1.8	2.9	1.7	0.1	1.6
Systolic Blood Pressure	0.3	1.4	1.6	-1.3	-1.2	-1.0
Hearing difficulty/problems: Yes	0.3	0.5	1.4	0.3	-1.2	0.1
Supplements: Zinc	0.3	0.4	0.9	-0.9	-0.2	-0.4
Pack years adult smoking proportion	0.3	0.5	1.2	1.1	0.2	0.4
Relative age voice broke	0.3	0.5	1.0	0.3	0.6	1.0
Impedance of leg (left)	0.3	1.4	2.9	-1.7	-0.5	-1.0
Waist circumference	0.3	0.9	2.6	0.4	-1.6	-0.1
Illnesses of siblings	0.3	0.4	0.6	-0.8	0.1	-0.8
Impedance of arm (right)	0.3	1.2	2.1	-1.1	-0.6	-1.4
Qualifications: A levels/AS levels or equivalent	0.3	0.7	2.1	-0.2	1.4	0.3
Serious illness, injury or assault of a close relative in last 2 years	0.3	0.3	0.5	-0.7	-0.6	-0.4
Whole body fat mass	0.3	1.2	2.0	1.4	-0.4	1.2
Handedness (chirality/laterality): Left-handed	0.3	0.3	0.7	-0.2	-0.9	-0.5
Mood swings	0.3	0.6	1.1	0.7	0.5	1.1
Illnesses of father: None of the above (group 1)	0.3	0.4	0.8	0.5	-0.5	0.9
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.3	0.6	1.7	0.0	1.3	0.4
Tinnitus: Yes, now most or all of the time	0.3	0.3	0.8	0.9	0.4	0.2
Alcohol drinker status: Never	0.3	0.3	0.9	0.9	0.4	0.2
Arm fat-free mass (left)	0.3	1.7	2.7	-1.2	-1.6	-0.9
Arm predicted mass (left)	0.3	1.7	2.6	-1.2	-1.6	-1.0
Alzheimer’s Disease (including proxy)	0.2	0.3	0.4	-0.7	-0.7	-0.4
Coronary Artery Disease (CAD)	0.2	0.2	0.5	-0.3	-0.7	-0.2
Smoking Status	0.2	0.6	1.1	0.7	-1.1	-0.1
Systolic blood pressure, automated reading	0.2	0.7	1.8	-0.4	-1.4	-0.2
Eye problems/disorders: Diabetes related eye disease	0.2	0.3	0.4	-0.5	-0.6	-0.3
Severe depression (siblings)	0.2	0.2	0.5	-0.7	-0.3	-0.4
Trunk fat mass	0.2	0.7	1.3	0.8	-1.1	0.6
Had menopause	0.2	0.2	0.5	0.4	0.3	0.7
Hip circumference	0.2	0.7	1.2	1.1	-0.6	0.8
Pulse wave Arterial Stiffness index	0.2	0.3	0.4	0.7	-0.3	0.5
Breastfed as a baby	0.2	0.3	0.4	-0.7	0.5	0.3
High blood pressure (siblings)	0.2	0.2	0.4	0.4	0.4	0.6
Comparative body size at age 10	0.2	0.6	1.4	1.2	-0.2	0.5
Health satisfaction	0.2	0.2	0.3	0.2	0.5	-0.6
Migraine (self-reported)	0.2	0.2	0.3	-0.6	-0.2	-0.6
Alcohol intake frequency.	0.2	0.5	1.2	0.4	-1.1	-0.5
Number of full sisters	0.2	0.2	0.5	0.2	-0.4	0.7
Age at last live birth	0.2	0.3	0.3	-0.5	0.5	-0.6
Loneliness, isolation	0.2	0.3	0.7	-0.4	-0.8	-0.2
Ever had stillbirth, spontaneous miscarriage or termination	0.2	0.2	0.3	-0.1	0.5	-0.5
Osteoarthritis (self-reported)	0.2	0.2	0.2	-0.5	-0.4	-0.5
Average weekly beer plus cider intake	0.2	0.3	0.6	0.8	0.0	0.6
Risk taking	0.2	0.4	0.6	-0.7	0.8	-0.1
Age started oral contraceptive pill	0.2	0.2	0.6	0.3	-0.3	0.7
Neuroticism (Nagel 2018)	0.1	0.3	0.9	0.4	0.0	1.0
Worry (Nagel 2018)	0.1	0.2	0.3	0.4	0.6	0.5
Body Mass Index (BMI) (2010)	0.1	0.1	0.3	-0.0	0.1	-0.5
Primary Biliary Cirrhosis	0.1	0.1	0.3	-0.5	-0.1	0.1
Hand grip strength (left)	0.1	0.3	0.8	-0.9	0.2	-0.1
Impedance of leg (right)	0.1	0.7	1.5	-1.2	0.1	-0.7
Hand grip strength (right)	0.1	0.3	0.7	-0.4	0.8	0.3
Average weekly fortified wine intake	0.1	0.2	0.4	0.0	0.7	0.1
Bilateral oophorectomy (both ovaries removed)	0.1	0.1	0.1	-0.3	-0.1	0.3
Diverticular disease/diverticulitis (self-reported)	0.1	0.1	0.1	0.2	-0.4	-0.3
Number of incorrect matches in round	0.1	0.2	0.5	-0.1	-0.1	0.7
Nervous feelings	0.1	0.2	0.4	0.3	0.6	0.5
Hair/balding pattern: Pattern 2	0.1	0.2	0.4	0.3	0.7	-0.0
Financial difficulties in last 2 years	0.1	0.2	0.4	-0.3	0.0	-0.6
Pain all over the body in last month	0.1	0.1	0.2	0.4	-0.4	-0.1
Weight	0.1	0.7	2.1	0.1	-1.4	-0.2
Time employed in main current job	0.1	0.1	0.2	-0.3	-0.5	-0.3
Worrier / anxious feelings	0.1	0.3	0.4	0.6	0.1	0.7
Medication: Lansoprazole	0.1	0.1	0.1	-0.2	-0.1	-0.3
Lung cancer (father)	0.1	0.1	0.3	0.5	0.0	0.3
Glaucoma (self-reported)	0.1	0.2	0.4	-0.3	0.2	-0.6
Chronic bronchitis/emphysema (mother)	0.1	0.2	0.4	0.2	-0.6	0.2
Age at first live birth	0.1	0.2	0.5	-0.2	0.2	-0.7
Suffer from ‘nerves’	0.1	0.1	0.2	0.0	-0.5	-0.2
Illnesses of siblings: Diabetes	0.1	0.1	0.2	-0.4	-0.0	-0.4
Average weekly red wine intake	0.1	0.1	0.2	-0.5	0.1	0.4
Friendships satisfaction	0.1	0.2	0.4	-0.1	0.6	-0.2
Breast cancer (self-reported)	0.1	0.1	0.2	0.4	-0.2	0.1
Eye problems/disorders: Glaucoma	0.1	0.1	0.1	-0.2	0.4	-0.4
Medication: Atorvastatin	0.1	0.1	0.2	-0.1	0.4	0.1
Pain experienced in last month	0.1	0.2	0.3	0.3	0.3	0.6
Heart disease (siblings)	0.1	0.1	0.1	-0.2	-0.4	-0.1
Ever had hysterectomy (womb removed)	0.0	0.0	0.0	-0.1	-0.0	0.1
Age when periods started (menarche)	0.0	0.1	0.1	-0.1	0.2	0.4
Loud music exposure frequency	0.0	0.1	0.1	0.0	0.3	0.2
Medication: Blood pressure	0.0	0.0	0.1	-0.2	-0.1	0.1
Heart disease (mother)	0.0	0.1	0.1	-0.3	-0.3	-0.1
Guilty feelings	0.0	0.0	0.1	0.0	-0.3	0.2
Medication: Bendroflumethiazide	0.0	0.0	0.1	0.3	0.0	-0.2
Number of operations (self-reported)	0.0	0.0	0.0	-0.0	0.1	0.1
Ever had prostate specific antigen (PSA) test	0.0	0.0	0.0	-0.2	0.2	0.1

Hub : Genes

C11orf10

Models

Trait associations