Best TWAS P=7.13e-09 · Best GWAS P=9.15e-07 conditioned to 0.623
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Muscle Skeletal | MDH2 | 0.21 | 0.05 | enet | 29 | 0.08 | 4.5e-08 | -4.7 | 5.8 | 7.1e-09 | -0.80 | 0.04 | 0.95 | TRUE |
2 | GTEx | Testis | MDH2 | 0.14 | 0.07 | lasso | 3 | 0.05 | 3.6e-03 | -4.8 | 5.2 | 2.4e-07 | -0.79 | 0.02 | 0.85 | FALSE |