Best TWAS P=8.2e-08 · Best GWAS P=1.16e-07 conditioned to 0.0431
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | ERI1 | 0.06 | 0.04 | lasso | 3 | 0.04 | 9.0e-06 | 5.0 | 5.4 | 8.2e-08 | 0.73 | 0.03 | 0.96 | TRUE |
| 2 | GTEx | Cells Transformed fibroblasts | ERI1 | 0.34 | 0.35 | lasso | 7 | 0.35 | 1.9e-27 | -4.5 | 5.1 | 3.0e-07 | 0.85 | 0.27 | 0.71 | FALSE |
| 3 | The Cancer Genome Atlas | Lung Adenocarcinoma | ERI1 | 0.06 | 0.04 | blup | 72 | 0.04 | 1.5e-05 | -4.6 | 5.2 | 2.2e-07 | 0.82 | 0.07 | 0.92 | FALSE |