Best TWAS P=5.57e-08 · Best GWAS P=1.13e-06 conditioned to 0.743
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Caudate basal ganglia | SEMA6C | 0.35 | 0.22 | lasso | 2 | 0.17 | 1.1e-05 | -4.6 | -5.2 | 1.5e-07 | 0.86 | 0.01 | 0.92 | FALSE |
| 2 | The Cancer Genome Atlas | Brain Lower Grade Glioma | BNIPL | 0.03 | 0.02 | blup | 35 | 0.02 | 6.4e-03 | -4.5 | -5.4 | 5.6e-08 | 0.87 | 0.00 | 0.40 | TRUE |