Best TWAS P=1.26e-07 · Best GWAS P=4.92e-08 conditioned to 0.017
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Cerebellum | ARTN | 0.47 | 0.33 | lasso | 5 | 0.43 | 6.0e-14 | 5.4 | 5.2 | 1.7e-07 | 0.82 | 0.04 | 0.96 | FALSE |
| 2 | GTEx | Brain Cortex | ARTN | 0.13 | 0.04 | lasso | 5 | 0.03 | 5.9e-02 | 5.4 | 5.2 | 1.5e-07 | 0.76 | 0.04 | 0.84 | FALSE |
| 3 | GTEx | Cells Transformed fibroblasts | CCDC24 | 0.07 | 0.00 | enet | 16 | 0.02 | 9.5e-03 | 3.8 | 5.2 | 1.6e-07 | 0.51 | 0.09 | 0.57 | FALSE |
| 4 | METSIM | Adipose | ARTN | 0.05 | 0.04 | bslmm | 412 | 0.03 | 1.3e-05 | 5.2 | 5.2 | 2.3e-07 | 0.81 | 0.06 | 0.94 | FALSE |
| 5 | The Cancer Genome Atlas | Prostate Adenocarcinoma | DPH2 | 0.03 | 0.03 | enet | 7 | 0.04 | 5.8e-05 | 4.4 | 5.3 | 1.3e-07 | 0.72 | 0.01 | 0.83 | TRUE |