Best TWAS P=1.07e-11 · Best GWAS P=4.74e-11 conditioned to 1
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Testis | AC074117.10 | 0.14 | 0.08 | lasso | 6 | 0.12 | 4.5e-06 | -3.8 | 5.5 | 3.2e-08 | 0.85 | 0.04 | 0.96 | FALSE |
2 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | FNDC4 | 0.13 | 0.06 | lasso | 2 | 0.05 | 1.1e-03 | 6.6 | -6.8 | 1.1e-11 | -0.99 | 0.00 | 0.94 | TRUE |
3 | The Cancer Genome Atlas | Thyroid Carcinoma | FNDC4 | 0.24 | 0.09 | enet | 9 | 0.17 | 1.9e-16 | -3.6 | -5.8 | 6.1e-09 | -0.70 | 0.34 | 0.66 | FALSE |