TWAS
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Traits
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Traits
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Alcohol intake versus 10 years previously
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chr8:27,099,879-27,720,371
Best TWAS P=1.06e-08 · Best GWAS P=4.55e-10 conditioned to 0.00304
27.1M
27.2M
27.3M
27.4M
27.5M
27.6M
27.7M
0
2
4
6
8
10
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
The Cancer Genome Atlas
Brain Lower Grade Glioma
CLU
0.04
0.00
blup
66
0.01
0.0106
-4.8
5.7
1.1e-08
-0.57
0.01
0.60
TRUE
1
The Cancer Genome Atlas
Glioblastoma Multiforme
EPHX2
0.15
0.12
lasso
7
0.12
0.0002
-5.3
-5.2
1.7e-07
0.49
0.16
0.32
TRUE