Best TWAS P=1.06e-08 · Best GWAS P=4.55e-10 conditioned to 0.00304
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | The Cancer Genome Atlas | Glioblastoma Multiforme | EPHX2 | 0.15 | 0.12 | lasso | 7 | 0.12 | 0.0002 | -5.3 | -5.2 | 1.7e-07 | 0.49 | 0.16 | 0.32 | TRUE |
| 2 | The Cancer Genome Atlas | Brain Lower Grade Glioma | CLU | 0.04 | 0.00 | blup | 66 | 0.01 | 0.0106 | -4.8 | 5.7 | 1.1e-08 | -0.57 | 0.01 | 0.60 | TRUE |