Hub : Genes

EPHX2

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.2140 0.0370 1.1e-16 0.226 0.153 0.196 0.205 0.233 4.2e-27 3.3e-18 2.6e-23 1.8e-24 5.8e-28
2 GTEx Adipose Subcutaneous 0.0930 0.0310 4.1e-04 0.062 NA 0.061 NA 0.061 8.3e-06 NA 1.0e-05 NA 1.0e-05
3 GTEx Adrenal Gland 0.2579 0.0635 1.6e-05 0.090 NA 0.156 NA 0.128 4.0e-04 NA 3.0e-06 NA 2.4e-05
4 GTEx Artery Aorta 0.2680 0.0640 1.6e-05 0.183 NA 0.191 NA 0.198 2.4e-10 NA 9.3e-11 NA 3.6e-11
5 GTEx Artery Tibial 0.2151 0.0568 5.9e-07 0.183 NA 0.177 NA 0.182 2.9e-14 NA 7.6e-14 NA 3.2e-14
6 GTEx Brain Cerebellum 0.3340 0.0930 4.6e-04 0.078 NA 0.066 NA 0.055 2.6e-03 NA 5.2e-03 NA 1.0e-02
7 GTEx Brain Cortex 0.3260 0.1140 9.3e-03 0.118 NA 0.068 NA 0.112 3.9e-04 NA 6.3e-03 NA 5.4e-04
8 GTEx Brain Frontal Cortex BA9 0.5007 0.1003 7.9e-05 0.301 NA 0.326 NA 0.376 1.1e-08 NA 2.0e-09 NA 6.4e-11
9 GTEx Breast Mammary Tissue (Male) 0.0425 0.0726 3.3e-01 -0.009 NA -0.012 NA 0.062 5.7e-01 NA 7.9e-01 NA 1.5e-02
10 GTEx Breast Mammary Tissue (Female) 0.0209 0.0586 4.0e-01 -0.008 NA -0.009 NA -0.008 6.9e-01 NA 7.2e-01 NA 7.0e-01
11 GTEx Cells Transformed fibroblasts 0.3500 0.0620 2.0e-10 0.131 NA 0.196 NA 0.179 5.2e-10 NA 1.3e-14 NA 2.1e-13
12 GTEx Colon Transverse 0.2390 0.0600 3.1e-06 0.151 NA 0.179 NA 0.194 1.1e-07 NA 6.5e-09 NA 1.4e-09
13 GTEx Esophagus Gastroesophageal Junction 0.4080 0.0780 2.5e-07 0.276 NA 0.258 NA 0.289 1.7e-10 NA 7.9e-10 NA 5.2e-11
14 GTEx Esophagus Mucosa 0.4730 0.0520 0.0e+00 0.283 NA 0.400 NA 0.372 3.6e-19 NA 2.1e-28 NA 4.2e-26
15 GTEx Esophagus Muscularis 0.1680 0.0560 2.8e-04 0.135 NA 0.086 NA 0.113 1.5e-08 NA 6.7e-06 NA 2.5e-07
16 GTEx Heart Atrial Appendage 0.3460 0.0710 1.2e-07 0.244 NA 0.180 NA 0.211 2.6e-11 NA 1.6e-08 NA 7.6e-10
17 GTEx Heart Left Ventricle 0.3348 0.0630 1.3e-09 0.251 NA 0.229 NA 0.225 1.3e-13 NA 2.0e-12 NA 3.3e-12
18 GTEx Lung 0.1656 0.0444 2.2e-05 0.075 NA 0.086 NA 0.108 2.2e-06 NA 4.3e-07 NA 1.4e-08
19 GTEx Muscle Skeletal 0.4743 0.0522 0.0e+00 0.290 NA 0.351 NA 0.346 1.2e-28 NA 9.8e-36 NA 4.5e-35
20 GTEx Nerve Tibial 0.2094 0.0520 1.4e-06 0.194 NA 0.159 NA 0.188 1.0e-13 NA 2.2e-11 NA 2.4e-13
21 GTEx Ovary 0.2770 0.1000 8.6e-03 0.076 NA 0.084 NA 0.110 6.5e-03 NA 4.4e-03 NA 1.2e-03
22 GTEx Pancreas 0.4080 0.0680 5.2e-09 0.245 NA 0.281 NA 0.272 1.0e-10 NA 2.6e-12 NA 6.5e-12
23 GTEx Skin Not Sun Exposed Suprapubic 0.4820 0.0690 7.2e-12 0.304 NA 0.244 NA 0.283 3.9e-17 NA 1.3e-13 NA 7.1e-16
24 GTEx Skin Sun Exposed Lower leg 0.3470 0.0530 1.9e-15 0.240 NA 0.264 NA 0.258 9.3e-20 NA 6.2e-22 NA 2.3e-21
25 GTEx Spleen 0.2920 0.1100 9.7e-03 0.148 NA 0.128 NA 0.134 1.3e-04 NA 3.7e-04 NA 2.6e-04
26 GTEx Testis 0.2640 0.0760 5.1e-04 0.099 NA 0.069 NA 0.066 3.8e-05 NA 5.3e-04 NA 7.1e-04
27 GTEx Thyroid 0.1700 0.0560 3.3e-04 0.076 NA 0.055 NA 0.073 2.0e-06 NA 4.8e-05 NA 3.1e-06
28 METSIM Adipose 0.0564 0.0191 4.2e-04 0.011 0.022 0.005 0.020 0.010 7.2e-03 2.6e-04 4.7e-02 4.1e-04 9.5e-03
29 ROSMAP Brain Pre-frontal Cortex 0.2064 0.0324 0.0e+00 0.225 0.205 0.229 0.232 0.225 2.0e-28 8.8e-26 6.2e-29 2.2e-29 2.1e-28
30 YFS Blood 0.2688 0.0305 0.0e+00 0.297 0.303 0.329 0.316 0.328 9.1e-99 5.4e-101 1.2e-111 3.8e-106 4.5e-111
31 TCGA Breast Invasive Carcinoma 0.0283 0.0117 1.1e-05 0.041 0.022 0.038 NA 0.037 7.6e-09 2.2e-05 2.6e-08 NA 3.4e-08
32 TCGA Cervical Squamous Cell Carcinoma 0.0610 0.0290 2.2e-03 0.064 0.055 0.067 NA 0.059 4.3e-04 1.1e-03 3.2e-04 NA 7.0e-04
33 TCGA Colon Adenocarcinoma 0.0950 0.0430 2.7e-03 0.004 0.023 -0.001 NA 0.000 1.9e-01 1.6e-02 3.7e-01 NA 3.2e-01
34 TCGA Glioblastoma Multiforme 0.1530 0.0650 4.8e-04 0.115 0.073 0.043 NA 0.118 2.3e-04 3.1e-03 2.0e-02 NA 2.0e-04
35 TCGA Head and Neck Squamous Cell Carcinoma 0.0734 0.0273 2.6e-08 0.064 0.077 0.077 NA 0.079 1.1e-07 4.9e-09 5.6e-09 NA 3.3e-09
36 TCGA Kidney Renal Clear Cell Carcinoma 0.1381 0.0353 0.0e+00 0.181 0.161 0.179 NA 0.179 6.5e-20 1.0e-17 9.9e-20 NA 1.1e-19
37 TCGA Kidney Renal Papillary Cell Carcinoma 0.1330 0.0480 3.2e-06 0.116 0.118 0.070 NA 0.104 3.9e-07 2.9e-07 7.8e-05 NA 1.5e-06
38 TCGA Liver Hepatocellular Carcinoma 0.1400 0.0700 4.4e-03 0.017 0.015 -0.002 NA 0.004 5.4e-02 6.5e-02 4.2e-01 NA 2.0e-01
39 TCGA Lung Adenocarcinoma 0.0563 0.0206 2.7e-07 0.053 0.066 0.071 NA 0.065 7.3e-07 3.3e-08 1.0e-08 NA 4.3e-08
40 TCGA Lung Squamous Cell Carcinoma 0.0266 0.0127 1.2e-03 0.017 0.022 0.015 NA 0.019 4.5e-03 1.3e-03 6.5e-03 NA 2.5e-03
41 TCGA Ovarian Serous Cystadenocarcinoma 0.1370 0.0580 1.1e-05 0.032 0.076 0.027 NA 0.037 3.2e-03 8.0e-06 6.1e-03 NA 1.6e-03
42 TCGA Pheochromocytoma and Paraganglioma 0.0770 0.0360 1.5e-03 0.067 0.066 0.059 NA 0.056 1.2e-03 1.3e-03 2.3e-03 NA 2.9e-03
43 TCGA Prostate Adenocarcinoma 0.0643 0.0216 2.8e-09 0.091 0.086 0.093 NA 0.096 8.9e-10 2.6e-09 6.1e-10 NA 3.4e-10
44 TCGA Rectum Adenocarcinoma 0.2460 0.1230 1.4e-03 0.108 0.154 0.066 NA 0.137 1.7e-03 1.9e-04 1.2e-02 NA 4.4e-04
45 TCGA Stomach Adenocarcinoma 0.0780 0.0360 3.1e-04 0.048 0.040 0.022 NA 0.041 2.2e-04 7.1e-04 8.8e-03 NA 5.5e-04
46 TCGA Testicular Germ Cell Tumors 0.1240 0.0590 1.5e-03 0.086 0.088 0.116 NA 0.093 5.7e-04 4.9e-04 6.7e-05 NA 3.5e-04
47 TCGA Thyroid Carcinoma 0.0740 0.0290 2.3e-06 0.055 0.073 0.067 NA 0.062 4.5e-06 1.3e-07 4.3e-07 NA 1.0e-06
48 TCGA Uterine Corpus Endometrial Carcinoma 0.1120 0.0630 9.0e-03 0.043 0.089 0.039 NA 0.057 2.4e-02 1.9e-03 2.9e-02 NA 1.1e-02

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48
Bipolar Disorder (2018) 1.6 2.5 5.5 1.2 1.4 1.0 1.6 1.9 1.6 1.4 0.9 1.4 0.0 1.7 1.9 2.1 2.1 1.7 1.4 1.3 1.9 1.1 1.7 1.5 1.7 1.7 1.3 1.9 -0.0 1.5 1.5 1.1 1.8 1.4 1.4 1.5 1.2 1.5 1.5 1.6 1.4 1.9 1.7 1.3 1.6 1.8 2.2 1.6 1.6 2.4 1.7
Bipolar Disorder or Schizophrenia 0.2 0.4 4.8 -0.5 0.2 0.8 0.1 0.3 -1.4 -0.4 -0.6 -0.4 0.0 -0.6 0.2 0.6 0.6 0.1 -0.1 -0.5 0.4 -0.9 0.3 0.5 0.3 0.5 -0.1 0.6 -1.1 -0.9 0.4 -0.5 0.5 0.1 -0.3 0.1 -2.2 0.1 0.3 0.8 -0.2 -0.3 0.3 0.4 -0.3 0.1 0.9 0.1 0.5 0.9 0.6
Depressed Affect (Nagel 2018) 0.9 1.9 4.5 -1.2 -1.2 -2.1 -1.1 -1.0 -0.1 -0.8 -0.6 -1.0 0.0 -1.7 -1.6 -1.3 -1.7 -1.0 -0.9 -0.9 -1.5 -0.7 -1.3 -1.9 -1.3 -1.5 -1.5 -1.4 -1.6 -1.1 -2.0 -1.1 -1.6 -1.5 -1.1 -2.0 -1.2 -1.4 -1.6 -1.5 -1.5 -1.4 -1.1 -0.7 -1.4 -1.6 -1.4 -1.4 -1.8 -1.6 -1.0
Depression (Nagel 2018) 0.1 0.2 0.8 0.7 0.8 0.4 0.1 0.1 0.2 0.6 0.9 0.5 0.0 0.6 0.1 -0.1 0.3 0.1 0.5 0.5 0.2 0.9 0.1 0.5 0.0 0.2 0.4 -0.2 0.7 0.2 -0.8 0.7 0.0 0.1 0.4 -0.3 0.6 0.3 0.3 0.3 -0.2 0.4 0.6 0.1 0.4 0.2 0.2 0.3 0.2 -0.3 0.2
Intelligence (Savage-Jansen 2018) 0.3 0.8 2.4 -0.2 -0.7 -0.4 -1.2 -1.5 0.5 -0.4 0.3 -0.9 0.0 -0.8 -0.7 -1.5 -0.4 -1.3 -0.6 -0.7 -1.1 -0.2 -1.3 -1.0 -0.8 -0.6 -0.8 -1.4 -1.2 -1.5 -0.8 -0.3 -0.8 -1.0 -0.9 -1.1 -1.1 -0.6 -0.4 -1.3 0.2 -1.1 -0.9 -0.5 -0.9 -0.7 -0.9 -0.6 -0.4 -1.2 -1.1
Neuroticism (Nagel 2018) 0.1 0.3 3.1 0.3 -0.0 -0.9 -0.1 0.3 0.4 0.3 0.2 0.2 0.0 -1.0 -0.2 0.1 -0.9 -0.1 0.3 0.2 -0.1 0.4 -0.2 -0.7 -0.4 -0.4 -0.7 -0.2 -0.2 -0.6 -1.5 0.2 -0.5 -0.3 0.1 -1.8 -0.8 -0.1 -0.4 -0.3 -1.5 -0.1 0.4 -0.4 0.0 -0.4 -0.1 -0.2 -0.6 -0.3 -0.1
Schizophrenia (2018) 0.9 2.0 14.5 -1.6 -0.9 0.1 -1.1 -1.1 -3.1 -1.7 -1.4 -1.6 0.0 -2.2 -1.2 -1.0 -1.0 -1.2 -1.3 -1.7 -1.1 -2.0 -1.0 -0.5 -1.0 -0.7 -1.2 -0.8 -1.6 -2.3 -0.7 -1.6 -0.9 -1.0 -1.5 -1.2 -3.8 -1.1 -0.8 -0.3 -1.4 -1.9 -1.1 -0.7 -1.7 -1.3 -0.7 -1.1 -0.6 -0.7 -0.6
Schizophrenia vs Biploar Disorder 0.3 0.4 7.8 -0.4 -0.5 -0.2 -0.0 -0.4 -1.7 -0.3 -0.4 -0.2 0.0 -1.1 -0.1 -0.4 -0.4 0.1 -0.2 -0.3 0.1 -0.4 0.1 -0.3 -0.1 0.0 0.1 0.1 0.4 -1.1 -0.1 -0.6 -0.2 0.2 -0.1 -0.6 -2.8 0.0 0.0 0.4 -0.9 -0.8 -0.2 -1.1 -0.1 -0.2 -0.7 -0.1 0.3 0.1 0.1
Worry (Nagel 2018) 0.3 0.7 5.8 -0.0 0.0 -0.4 -0.6 -0.2 0.7 -0.1 -0.2 -0.5 0.0 -1.3 -0.3 -0.2 -1.1 -0.7 -0.3 -0.4 -0.6 -0.2 -0.6 -0.8 -0.7 -0.5 -1.1 -0.6 -0.5 -1.3 -2.4 -0.4 -0.7 -0.4 -0.4 -1.9 -1.7 -0.5 -0.3 -0.4 -2.0 -0.5 0.1 -1.0 -0.4 -0.5 -0.5 -0.6 -0.7 -0.7 -0.6
Alzheimer’s Disease (in mother) 2.3 2.7 8.0 1.7 1.1 1.0 2.4 2.7 2.8 1.8 1.2 2.3 0.0 2.5 2.0 2.5 0.8 2.3 1.4 2.1 1.3 1.9 1.9 2.4 0.4 -0.0 0.3 1.7 -0.9 2.7 -0.4 1.6 0.3 -0.1 2.4 1.6 2.6 0.4 -0.0 0.3 -0.5 2.0 1.6 1.1 2.0 0.7 1.7 0.9 0.7 1.0 1.0
Alzheimer’s Disease (in father) 2.0 2.1 6.1 2.2 1.7 1.4 1.6 1.7 1.3 1.6 1.7 1.9 0.0 1.8 2.1 1.7 1.2 1.6 1.6 2.0 0.9 1.9 1.2 1.9 0.9 0.0 0.6 1.0 0.7 2.1 0.7 2.0 0.4 0.5 2.1 0.8 2.5 0.8 0.5 1.1 -0.1 1.6 2.1 1.4 2.0 0.9 1.7 1.1 0.7 1.0 1.1
Alzheimer’s Disease (including proxy) 3.4 5.0 16.9 2.5 1.9 1.8 3.2 3.5 3.3 2.4 1.8 3.1 0.0 3.1 3.0 3.4 1.3 3.0 1.8 3.0 1.5 2.3 2.4 3.1 0.5 -0.7 0.1 2.0 -0.7 3.9 -0.4 2.2 0.3 -0.2 3.2 1.3 4.1 0.5 -0.2 0.6 -1.4 2.6 3.0 1.5 3.0 0.8 2.9 1.0 0.6 1.5 1.2
Crohns Disease (2017) 0.3 0.7 2.1 0.4 0.4 -0.1 0.9 0.8 0.6 0.7 0.3 0.9 0.0 0.5 0.7 0.7 0.4 1.2 1.0 0.7 1.1 0.6 1.1 0.5 0.7 0.8 0.9 1.1 1.3 1.0 0.1 0.8 1.1 0.8 0.8 1.5 0.5 0.9 0.8 1.0 1.2 0.8 0.4 1.2 0.3 0.9 1.0 0.8 1.0 0.9 1.3
Irritable Bowel Disease (IBD) 0.7 1.6 3.7 1.1 1.2 0.4 0.9 0.8 1.7 1.4 1.2 1.2 0.0 0.9 1.2 0.7 1.0 1.1 1.4 1.1 1.5 1.2 1.2 0.7 1.2 1.4 1.4 1.0 1.9 1.2 0.6 1.4 1.7 1.5 1.2 1.3 1.2 1.6 1.6 1.2 1.6 1.4 1.1 1.5 0.7 1.6 1.7 1.4 1.6 0.9 1.6
Ulcerative Colitis (UC) 0.6 1.1 3.3 1.1 1.2 0.6 0.5 0.4 1.8 1.2 1.3 0.9 0.0 0.7 1.0 0.4 1.0 0.6 1.0 0.9 1.1 1.1 0.7 0.5 1.0 1.2 1.1 0.5 1.6 0.7 0.9 1.2 1.4 1.2 0.9 0.5 1.0 1.3 1.5 0.7 1.0 1.1 1.1 0.9 0.6 1.4 1.6 1.2 1.3 0.6 1.1
Major Depression (MDD) 1.6 2.0 6.3 -1.5 -2.0 -1.3 -1.3 -1.3 -0.5 -1.6 -1.1 -1.6 0.0 -0.9 -1.6 -1.3 -1.3 -1.3 -1.7 -1.7 -1.2 -1.4 -1.3 -1.3 -1.7 -0.8 -0.8 -1.2 -1.4 -1.7 -1.6 -1.5 -1.3 -1.0 -1.7 -0.4 -2.0 -1.4 -1.4 -1.4 -1.1 -1.6 -1.9 -0.0 -2.5 -1.3 -1.3 -1.5 -1.5 -1.4 -0.8
Reaction Time 0.6 1.2 3.7 -0.7 -0.1 -0.2 -1.4 -1.4 -0.3 -1.1 -0.6 -1.4 0.0 -1.5 -0.8 -1.1 -0.7 -1.6 -1.1 -1.4 -1.0 -1.5 -1.3 -1.2 -1.1 -0.2 -0.6 -1.3 -0.3 -1.9 -1.2 -1.4 -0.6 -0.4 -1.4 -1.7 -1.9 -0.6 -0.2 -0.8 -1.0 -1.2 -0.9 -0.8 -1.7 -0.7 -0.6 -0.7 -1.1 -1.4 -0.9
Verbal and Numeric Reasoning (VNR) 0.3 0.6 2.8 -0.5 -1.3 -0.8 -1.0 -1.2 0.4 -0.4 -0.2 -0.8 0.0 -0.5 -0.4 -1.1 -0.2 -1.1 -0.7 -0.7 -0.8 -0.3 -0.9 -0.9 -0.4 -0.1 -0.4 -1.0 -0.9 -1.4 0.5 -0.4 -0.5 -0.5 -0.9 -0.0 -1.4 -0.3 -0.4 -0.9 0.4 -1.0 -1.6 0.0 -1.7 -0.6 -1.2 -0.5 -0.2 -0.9 -0.2
Breast Cancer 0.6 1.3 6.9 0.5 0.1 0.5 1.4 1.6 1.3 0.7 0.1 0.9 0.0 2.2 1.0 1.8 1.2 1.1 0.4 0.7 1.4 0.2 1.4 0.9 0.5 1.1 0.8 1.5 1.2 2.0 0.9 0.4 1.2 0.6 0.9 1.6 2.6 0.6 0.7 0.5 1.8 1.7 0.8 1.4 1.2 1.1 0.7 0.6 1.2 1.1 0.7
Ovarian Cancer 0.3 0.4 3.5 -0.1 -0.4 0.2 -1.0 -1.0 1.9 -0.3 0.3 -0.5 0.0 0.2 -0.5 -0.9 -0.2 -1.1 -0.0 -0.4 -1.0 0.2 -1.1 -0.2 -0.3 -0.5 -0.1 -1.1 -1.1 -0.4 -0.0 -0.2 -0.7 -0.5 -0.6 0.6 0.6 -0.4 -0.4 -0.5 0.3 -0.5 -0.8 -0.0 -0.8 -0.6 -0.7 -0.4 -0.4 -1.2 -0.3
Prostate Cancer 2.5 3.4 7.7 2.2 2.6 1.8 0.6 0.6 1.3 2.1 2.1 1.5 0.0 0.3 1.9 0.8 2.2 0.5 2.2 1.7 1.6 1.6 1.0 0.9 2.5 2.3 1.6 0.9 1.9 0.6 2.0 2.0 2.4 2.7 1.6 0.4 0.5 2.7 2.8 2.7 2.3 1.6 2.4 1.9 1.9 2.3 1.6 2.5 2.0 2.2 2.2
Age at First Birth 0.3 0.4 1.7 0.5 0.3 1.1 0.5 0.7 1.1 0.7 0.4 0.5 0.0 0.6 0.6 0.8 0.3 0.4 0.5 0.5 0.6 0.4 0.5 0.9 0.6 0.6 0.2 0.6 0.7 0.4 0.5 0.9 0.8 0.5 0.5 -0.2 0.3 0.7 0.8 0.3 1.3 0.6 0.6 0.3 0.9 0.7 0.5 0.8 0.6 0.9 0.2
Bipolar Disorder (2011) 1.6 1.5 13.0 1.4 1.3 0.6 0.8 0.8 3.6 1.4 1.4 1.3 0.0 1.8 1.3 0.8 1.2 0.9 1.6 1.4 0.9 1.5 0.8 1.2 0.9 0.9 0.6 0.8 0.7 1.2 -0.7 1.3 0.9 1.1 1.3 1.2 1.7 1.2 1.0 1.0 1.1 1.2 1.2 1.9 0.8 1.1 1.1 1.2 0.9 0.5 1.4
Body Mass Index (BMI) (2010) 0.1 0.2 0.7 -0.2 -0.5 -0.9 0.6 0.6 -0.6 -0.1 -0.6 0.1 0.0 -0.0 -0.2 0.4 -0.7 0.6 -0.2 -0.0 0.1 -0.2 0.4 0.1 -0.4 -0.8 -0.4 0.4 0.1 0.7 -0.5 -0.0 -0.4 -0.9 0.2 -0.4 0.6 -0.5 -0.8 -0.9 -0.4 0.3 -0.1 -0.1 0.1 -0.3 0.5 -0.5 -0.4 -0.3 -0.4
Coronary Artery Disease (CAD) 0.7 0.9 4.2 -1.2 -0.6 -0.8 -0.3 -0.3 0.2 -0.8 -0.8 -0.6 0.0 -0.9 -0.9 -0.3 -1.0 -0.1 -0.8 -0.7 -0.6 -0.9 -0.4 -0.2 -1.2 -0.8 -1.1 -0.3 -1.3 -0.7 -1.9 -0.7 -0.9 -0.9 -0.8 -0.7 -1.6 -1.0 -1.2 -0.4 -2.1 -1.1 -0.9 -0.5 -1.2 -1.2 -0.7 -1.1 -1.3 -0.4 -0.6
Crohns Disease (2012) 0.3 0.5 2.0 0.0 0.4 0.2 0.5 0.5 0.8 0.2 -0.2 0.3 0.0 0.3 0.7 0.7 0.7 0.7 0.5 0.2 1.0 0.2 0.9 0.6 0.6 1.2 1.0 1.0 0.8 0.5 -0.6 0.0 1.0 0.8 0.3 1.4 -0.3 0.8 0.8 1.1 0.8 0.5 0.2 0.9 0.1 0.8 0.6 0.6 0.9 0.7 1.0
Mean Putamen Volume 1.4 1.6 4.7 -0.9 -1.0 -1.7 -1.9 -1.8 -1.4 -1.2 -0.5 -1.4 0.0 -1.8 -1.3 -1.6 -0.6 -1.9 -0.9 -1.3 -1.4 -1.4 -1.6 -2.2 -1.0 -0.7 -0.9 -1.4 0.0 -1.9 -1.3 -1.4 -0.9 -0.8 -1.6 -1.1 -1.3 -0.9 -0.6 -0.8 0.1 -1.5 -1.1 -0.6 -1.4 -1.0 -1.1 -0.9 -1.3 -1.0 -0.8
Fasting Glucose 0.1 0.2 1.2 -0.9 -0.3 0.4 0.2 0.0 -0.6 -0.4 -1.0 -0.4 0.0 -0.5 -0.3 -0.0 -0.2 0.1 -0.5 -0.5 0.1 -0.9 0.2 0.3 -0.2 -0.5 -0.0 0.3 -0.4 0.2 -0.2 -1.1 -0.3 -0.2 -0.4 0.4 0.0 -0.2 -0.5 0.1 0.0 -0.1 -0.2 -0.8 0.5 -0.0 -0.2 -0.4 -0.1 0.4 -0.4
HbA1C 0.5 0.5 3.1 -0.6 -0.6 -0.1 0.6 0.8 -1.8 -0.8 -1.5 -0.3 0.0 -0.4 -0.0 0.9 -0.7 0.5 -1.1 -0.7 0.3 -1.3 0.5 0.3 -0.3 -0.8 -0.5 0.7 -1.1 -0.0 -0.8 -0.8 -0.6 -1.1 -0.2 0.1 -0.7 -0.8 -1.0 -0.3 -1.2 -0.2 -0.5 -0.7 -0.6 -0.4 0.7 -0.7 -0.8 -0.0 -0.2
HDL Cholesterol 0.9 1.6 3.6 -0.7 -1.0 -1.4 -1.5 -1.4 -0.4 -0.9 -0.2 -1.2 0.0 -1.2 -1.4 -1.5 -1.4 -1.3 -1.2 -1.0 -1.6 -0.5 -1.6 -1.6 -0.8 -1.3 -1.5 -1.6 -0.9 -1.2 -0.8 -0.4 -1.6 -1.4 -1.2 -1.4 -0.5 -1.4 -1.2 -1.9 -1.0 -1.3 -1.3 -1.6 -1.2 -1.4 -1.4 -1.3 -1.4 -1.6 -1.6
LDL Cholesterol 0.2 0.4 1.8 -1.4 -0.8 -0.2 -0.3 -0.1 0.1 -0.6 -1.0 -0.8 0.0 -0.2 -0.4 0.1 0.1 -0.3 -0.9 -1.0 -0.3 -1.4 -0.3 -0.4 -0.8 0.1 -0.4 -0.1 -0.9 -0.6 -0.1 -1.3 -0.2 -0.5 -0.9 -0.2 -0.9 -0.5 -0.5 -0.3 -0.5 -0.5 -0.8 -0.5 -0.8 -0.6 -0.3 -0.8 -0.6 -0.3 -0.5
Lupus 0.1 0.2 1.2 0.9 0.2 0.2 0.1 0.1 0.5 0.5 0.3 0.5 0.0 0.6 0.7 0.1 0.1 0.3 0.3 0.6 0.3 0.5 0.3 0.2 0.5 0.3 0.3 0.1 -0.3 0.5 1.0 0.5 0.4 0.6 0.6 0.1 0.8 0.5 0.4 -0.1 0.7 0.5 0.4 1.1 0.3 0.5 0.2 0.8 0.1 0.0 0.4
Neuroticism (2016) 1.1 1.6 7.7 -0.3 -0.3 -1.9 -0.8 -0.5 -1.4 -0.9 -0.2 -0.6 0.0 -1.4 -1.5 -0.8 -1.7 -1.0 -0.7 -0.4 -1.3 -0.4 -1.1 -1.6 -1.5 -1.8 -1.7 -1.2 -0.8 -1.0 -2.0 -0.2 -1.8 -1.3 -0.7 -2.6 -1.2 -1.3 -1.5 -1.0 -2.8 -1.2 0.1 -1.5 -0.5 -1.6 -0.7 -1.0 -1.8 -1.5 -1.2
Primary Biliary Cirrhosis 0.7 0.9 4.0 -0.7 -0.5 -0.3 -0.5 -0.7 -0.7 -0.6 -0.2 -0.6 0.0 -0.9 -1.1 -1.0 -1.3 -0.5 -0.8 -0.6 -1.0 -0.5 -0.8 -0.5 -0.9 -1.5 -0.9 -0.9 -1.6 -0.6 0.1 -0.6 -1.3 -1.4 -0.6 -1.3 -1.0 -1.1 -1.1 -1.2 -1.9 -1.1 -0.6 -2.0 -0.3 -1.3 -0.5 -0.9 -1.1 -0.8 -1.5
Rheumatoid Arthritis 0.3 0.4 2.1 0.1 -0.7 -1.3 -0.4 -0.6 -1.3 -0.2 0.1 -0.2 0.0 -1.1 -0.5 -0.9 -0.7 -0.3 -0.3 -0.2 -0.4 0.1 -0.3 -0.7 -0.6 -0.5 -0.6 -0.6 -0.9 -0.8 -0.3 -0.2 -0.6 -0.4 -0.2 -1.3 -1.4 -0.3 -0.4 -0.5 -0.2 -0.7 -0.5 -0.1 -0.5 -0.5 -0.7 -0.3 -0.5 -0.2 -0.2
Schizophrenia (2014) 0.4 0.9 14.9 -0.8 0.1 1.0 -0.5 -0.4 -2.0 -0.9 -0.8 -1.0 0.0 -1.9 -0.4 -0.2 -0.3 -0.5 -0.6 -1.1 -0.2 -1.2 -0.3 0.3 -0.1 0.1 -0.3 -0.0 -1.1 -1.9 0.1 -1.1 -0.0 -0.2 -0.8 -0.8 -3.9 -0.3 0.1 0.8 -1.1 -1.1 -0.2 -0.8 -0.7 -0.5 -0.0 -0.3 0.0 0.3 0.0
Triglycerides 0.2 0.3 1.7 -0.7 -0.2 0.2 0.6 0.7 -0.3 -0.9 -1.3 -0.4 0.0 0.3 -0.1 0.8 -0.0 0.4 -0.7 -0.7 0.2 -1.1 0.5 0.2 -0.6 -0.2 -0.4 0.7 0.2 0.3 0.5 -1.0 -0.1 -0.6 -0.2 -0.5 -0.2 -0.5 -0.4 0.3 -0.5 0.0 0.3 -0.6 0.4 -0.2 0.6 -0.5 -0.2 0.5 -0.3
Type 2 Diabetes (T2D) (2012) 0.8 1.0 2.5 1.4 1.3 0.9 0.9 1.2 0.7 1.3 1.1 1.1 0.0 1.1 0.8 1.1 0.8 0.8 1.0 1.2 0.8 1.0 0.8 1.0 1.0 0.5 0.7 0.9 0.7 1.2 0.3 1.3 0.7 0.6 1.3 0.8 1.6 0.9 0.9 0.7 0.8 1.2 1.3 0.8 1.3 0.9 0.9 1.0 0.8 1.0 0.7
Ulcerative Colitis 1.5 2.2 5.2 2.0 2.0 1.0 0.7 0.6 1.9 1.9 2.1 1.5 0.0 1.0 1.3 0.4 1.6 0.7 1.9 1.6 1.4 2.0 1.0 0.9 1.5 1.6 1.5 0.6 2.3 1.0 0.2 2.0 1.6 1.8 1.5 0.3 1.2 1.9 2.0 1.3 1.1 1.5 1.8 1.1 1.4 1.9 1.8 1.8 1.7 0.9 1.3
Blood Eosinophil Count 0.4 3.4 9.9 -2.2 -2.6 -0.7 -2.2 -2.3 -0.4 -2.2 -1.5 -2.4 0.0 -1.8 -2.0 -1.9 -1.4 -2.2 -2.1 -2.5 -1.6 -2.4 -2.0 -1.5 -1.8 -0.3 -0.8 -1.6 -1.4 -2.8 -0.2 -2.6 -1.2 -1.1 -2.5 0.4 -3.0 -1.2 -1.0 -1.2 0.0 -2.2 -3.2 -1.7 -3.0 -1.4 -2.5 -1.5 -1.0 -0.9 -1.2
Blood Platelet Count 0.1 1.4 5.0 -0.5 -0.3 -1.5 -1.7 -1.5 -0.9 -1.3 -0.4 -1.6 0.0 -0.9 -0.7 -1.1 -0.6 -1.8 -0.8 -1.4 -1.2 -0.8 -1.6 -2.2 -1.9 -0.3 -0.8 -1.5 0.5 -1.6 -1.4 -1.2 -0.9 -0.4 -1.4 -1.3 -1.4 -0.7 -0.4 -0.9 -0.6 -1.2 -0.9 -1.2 -1.1 -0.8 -1.5 -0.9 -1.1 -1.6 -1.3
Blood Red Count 0.0 0.2 1.8 -0.0 -0.3 0.3 0.4 0.3 0.1 0.3 -0.6 0.3 0.0 0.5 0.4 0.2 0.2 0.5 0.4 0.3 0.2 0.4 0.4 0.2 0.6 0.2 0.6 0.5 1.2 0.5 -1.3 0.3 0.1 0.2 0.4 -0.1 0.4 0.2 0.0 0.4 0.0 0.3 0.5 0.1 0.7 0.2 0.5 0.1 0.4 0.6 0.2
Blood White Count 0.4 3.2 13.8 -1.4 -2.9 -3.7 -2.1 -2.1 -0.3 -1.9 -1.1 -2.2 0.0 -1.5 -1.3 -1.6 -1.2 -2.1 -1.9 -2.2 -1.4 -1.4 -1.7 -2.8 -1.4 0.1 -0.8 -1.5 -0.0 -2.9 -0.5 -2.0 -0.9 -0.6 -2.1 0.3 -3.4 -1.0 -0.6 -0.8 0.3 -2.0 -3.1 0.7 -3.7 -1.1 -2.5 -1.1 -0.8 -1.3 0.0
Heel T-Score 0.7 5.6 13.3 -2.7 -3.6 -3.1 -1.2 -1.2 -2.8 -2.7 -3.1 -2.3 0.0 -1.7 -2.3 -1.1 -2.7 -1.3 -2.8 -2.4 -2.0 -2.8 -1.6 -2.1 -2.4 -2.5 -2.9 -1.3 -3.3 -1.4 -2.0 -2.3 -2.4 -2.8 -2.2 -1.3 -1.9 -2.8 -2.9 -2.9 -1.5 -2.3 -3.0 -1.2 -3.0 -2.6 -2.8 -2.7 -2.5 -2.3 -2.0
BMI 0.2 1.1 5.6 -0.2 0.2 -1.9 -1.5 -1.4 2.0 -0.4 0.7 -0.8 0.0 -0.8 -0.9 -1.5 -0.8 -1.2 -0.2 -0.5 -1.2 0.5 -1.5 -2.4 -1.2 -0.6 -0.4 -1.6 1.2 -0.7 -0.2 -0.6 -1.2 -0.3 -0.8 -1.0 0.5 -0.6 -0.5 -0.6 -1.8 -0.8 -0.2 -1.4 -0.6 -0.7 -0.4 -0.6 -1.0 -2.0 -1.1
Height 0.1 1.1 8.5 1.8 1.5 0.5 -0.3 -0.3 1.9 1.2 2.2 0.7 0.0 0.2 -0.2 -0.9 -0.5 -0.3 0.8 1.0 -0.2 2.3 -0.3 -0.3 1.2 0.1 0.5 -0.7 1.7 -0.3 -2.9 1.9 -0.2 0.2 0.8 -1.3 0.1 0.5 0.7 -0.3 -1.5 0.3 1.4 -0.5 0.9 0.4 0.9 0.6 0.4 -0.4 -0.3
Waist Hip Ratio (WHR) 0.3 1.2 5.9 -0.5 0.1 -0.1 -1.1 -1.2 0.4 -1.1 -0.7 -1.2 0.0 -1.4 -1.0 -1.2 -0.8 -1.1 -0.6 -1.1 -1.2 -1.0 -1.2 -1.3 -1.4 -1.2 -1.5 -1.2 -0.6 -1.2 -1.3 -1.1 -1.3 -0.9 -1.0 -1.3 -1.2 -1.0 -0.9 -0.3 -2.4 -1.2 -0.2 -1.6 -0.6 -1.0 -0.3 -1.1 -1.2 -1.1 -1.2
Systolic Blood Pressure 0.1 0.7 3.7 -1.4 -1.8 -0.7 0.3 0.5 -1.2 -0.8 -1.9 -0.4 0.0 -0.0 -0.3 0.6 -0.2 0.3 -0.9 -0.7 -0.1 -1.5 0.2 0.4 -1.0 -0.5 -0.9 0.5 -1.9 0.1 0.3 -0.7 -0.4 -1.1 -0.5 1.4 -0.1 -0.9 -1.1 -1.3 -0.2 -0.3 -1.5 -0.4 -1.2 -0.6 -0.5 -0.8 -0.0 -0.5 -0.3
Smoking Status 5.4 13.0 66.7 -2.6 -2.2 -3.0 -4.1 -4.0 -1.8 -3.2 -1.3 -3.9 0.0 -4.8 -3.8 -3.7 -3.2 -4.3 -3.2 -3.6 -3.6 -3.1 -4.1 -4.5 -3.2 -1.9 -2.7 -3.8 -2.1 -6.4 -3.2 -3.9 -3.5 -2.5 -3.9 -5.3 -8.2 -2.6 -2.0 -1.5 -3.9 -4.6 -2.7 -3.6 -3.7 -3.4 -3.7 -2.8 -3.2 -2.5 -2.6
Allergy or Eczema 0.2 0.5 2.1 -0.5 -1.1 -0.3 -0.4 -0.3 -1.0 -1.1 -1.4 -0.6 0.0 -0.1 -0.2 -0.1 -0.6 -0.4 -1.0 -0.8 -0.5 -1.0 -0.4 -0.1 -0.9 -0.7 -1.0 -0.3 -1.2 -0.5 -0.1 -0.9 -0.7 -0.7 -0.6 0.3 -0.3 -0.8 -1.0 -0.7 -0.5 -0.6 -1.0 -0.0 -1.0 -0.6 -0.5 -0.8 -0.7 -0.2 -0.4
Cardiovascular Disease 0.1 0.3 3.9 -0.6 -1.4 -2.0 0.1 0.3 -0.4 -0.5 -0.9 -0.2 0.0 -0.3 -0.3 0.4 -0.7 0.2 -0.4 -0.3 -0.1 -0.8 0.1 -1.1 -0.6 -0.3 -0.6 0.2 -0.6 -0.1 1.0 -0.5 -0.4 -0.3 -0.2 0.6 -0.3 -0.4 -0.7 0.0 -0.3 -0.1 -0.7 0.2 -0.7 -0.4 -0.6 -0.3 -0.3 -0.2 0.4
Hypothyroidism (self reported) 0.9 2.2 5.0 -1.9 -2.2 -1.7 -1.1 -1.3 -0.7 -1.8 -1.9 -1.7 0.0 -1.1 -1.6 -1.4 -1.2 -1.0 -2.0 -1.9 -1.1 -1.9 -1.0 -1.5 -1.5 -1.4 -1.3 -1.0 -0.9 -1.1 -0.4 -2.0 -1.4 -1.6 -1.7 -0.3 -1.3 -1.7 -1.6 -1.5 -1.4 -1.6 -1.8 -1.1 -1.9 -1.5 -1.3 -1.9 -1.6 -1.4 -1.2
Respiratory disease 0.4 0.8 2.2 -0.2 -0.5 -0.9 -1.1 -0.7 0.6 -0.8 0.2 -0.9 0.0 -1.3 -0.6 -0.6 -1.3 -1.1 -0.8 -0.8 -1.0 -0.6 -1.2 -1.0 -1.1 -1.0 -1.2 -1.1 -1.5 -1.1 -0.3 -0.8 -1.0 -0.9 -0.9 -1.1 -1.0 -0.8 -0.8 -1.2 -0.4 -0.9 -1.1 -0.8 -1.1 -0.9 -0.8 -0.9 -0.6 -0.9 -1.0
Type 2 Diabetes (T2D) (2018) 0.3 0.6 2.3 -0.5 -0.4 -0.6 -1.1 -1.2 -0.9 -0.5 -0.0 -0.7 0.0 -1.1 -1.1 -1.3 -0.8 -1.0 -0.5 -0.7 -0.8 -0.2 -1.0 -1.0 -0.3 -0.5 0.1 -1.1 -0.3 -0.7 0.5 -0.2 -0.7 -0.2 -0.8 0.3 -0.0 -0.4 -0.4 -1.2 -0.4 -0.7 -1.2 -0.8 -1.1 -0.4 -0.8 -0.6 -0.1 -1.5 -0.8
Lung FEV1/FVC ratio 0.4 2.1 7.6 1.8 1.8 0.7 1.5 1.5 0.3 2.2 1.9 2.0 0.0 1.3 0.9 1.0 0.9 1.7 2.0 2.2 1.0 2.2 1.2 0.6 2.0 0.3 0.8 1.0 1.1 1.7 0.2 2.1 0.5 0.9 2.0 0.1 1.9 1.1 0.8 1.5 -1.0 1.6 2.6 -0.1 2.8 1.0 1.5 1.4 1.3 0.7 0.9
Lung FVC 0.1 0.5 2.1 -0.6 -1.1 -1.5 0.6 0.8 -0.9 -0.6 -1.2 -0.1 0.0 0.7 -0.2 0.8 -0.2 0.4 -0.6 -0.3 -0.1 -0.8 0.4 -0.2 -0.5 -0.6 -1.3 0.6 -1.3 1.0 -0.3 -0.5 -0.4 -1.1 -0.1 0.2 1.4 -0.9 -0.9 -1.0 0.7 0.2 -0.4 -0.4 0.2 -0.6 -0.6 -0.8 -0.5 -0.1 -0.7
Neuroticism 0.5 1.2 5.7 -0.2 -0.3 -1.5 -1.0 -0.8 0.7 -0.4 0.0 -0.7 0.0 -1.2 -1.1 -0.9 -1.6 -1.0 -0.5 -0.5 -1.3 -0.1 -1.2 -1.8 -0.9 -1.0 -1.2 -1.2 -1.1 -1.4 -2.4 -0.5 -1.2 -0.9 -0.6 -2.2 -1.5 -0.9 -0.9 -1.0 -2.0 -1.0 -0.4 -0.6 -1.1 -1.1 -0.8 -0.8 -1.3 -1.3 -0.7
Chronotype (morning person) 1.0 2.4 11.6 -1.6 -2.8 -3.4 -1.1 -0.8 -1.1 -1.6 -1.7 -1.5 0.0 -0.8 -1.6 -0.6 -2.0 -1.2 -1.7 -1.6 -1.3 -1.6 -1.2 -2.4 -2.0 -1.5 -1.7 -1.1 -0.4 -1.0 -0.0 -1.5 -1.5 -1.3 -1.6 -1.2 -0.9 -1.6 -1.8 -1.8 -0.8 -1.2 -1.8 -0.6 -1.7 -1.5 -2.0 -1.7 -2.0 -1.2 -1.4
Hair Pigment 0.0 1.3 3.2 1.6 1.3 0.7 0.4 0.3 1.6 1.2 1.3 0.9 0.0 1.6 1.1 0.3 1.3 0.4 1.3 1.1 0.9 1.4 0.7 0.7 1.3 1.6 1.2 0.5 1.7 0.6 -0.4 1.6 1.3 1.3 1.1 0.2 1.0 1.5 1.6 0.6 1.4 1.1 1.3 1.8 0.8 1.4 1.3 1.4 0.9 0.9 0.9
Tanning 0.3 3.1 8.1 -1.2 -1.3 -1.8 -1.5 -1.5 -0.7 -1.2 -0.4 -1.5 0.0 -2.1 -2.1 -1.9 -2.2 -1.4 -1.5 -1.4 -2.2 -0.9 -2.0 -1.8 -1.3 -2.3 -2.0 -2.0 -2.3 -1.5 -2.1 -1.1 -2.2 -2.1 -1.5 -2.8 -1.4 -1.9 -2.0 -1.9 -2.1 -1.9 -1.3 -1.7 -1.3 -2.1 -1.8 -1.9 -2.1 -1.5 -2.0
Hand grip strength (left) 0.2 0.4 2.5 0.7 0.9 0.0 0.8 0.6 0.9 0.6 0.7 0.9 0.0 1.1 0.4 0.4 0.2 0.7 0.8 0.9 0.3 1.6 0.6 0.2 0.9 -0.0 0.1 0.4 0.6 0.8 0.1 1.0 -0.1 -0.0 0.8 0.1 0.9 0.1 0.0 0.7 -0.6 0.5 1.1 0.1 1.1 0.1 0.7 0.2 0.3 0.3 0.3
Number of treatments/medications taken 0.8 1.4 4.7 -0.9 -1.3 -2.2 -1.1 -0.5 0.5 -1.1 -0.6 -1.2 0.0 -1.1 -0.8 -0.3 -1.5 -1.0 -1.1 -1.2 -1.1 -1.1 -1.1 -1.7 -1.7 -1.2 -1.4 -0.9 -1.2 -1.4 -1.6 -1.5 -1.2 -1.0 -1.2 -0.9 -1.3 -1.2 -1.2 -1.0 -0.7 -1.0 -1.4 -0.2 -1.6 -1.2 -1.5 -1.2 -1.3 -1.2 -0.7
Average weekly spirits intake 0.6 0.7 3.1 0.9 0.7 -0.4 1.3 1.3 1.3 0.7 0.4 1.1 0.0 1.0 1.2 1.3 0.9 1.2 0.7 1.0 0.8 0.7 1.0 0.7 0.4 -0.2 -0.3 0.9 0.7 1.5 0.2 0.7 0.4 0.2 1.1 0.2 1.8 0.4 0.1 0.2 0.5 1.1 0.9 0.0 1.4 0.5 0.2 0.5 0.4 0.8 0.1
Sensitivity / hurt feelings 0.9 1.6 8.1 -0.2 0.7 -0.2 -1.8 -1.7 0.4 -0.7 0.4 -1.3 0.0 -1.8 -1.2 -1.6 -1.1 -1.9 -0.7 -1.1 -1.2 -0.5 -1.6 -2.2 -0.9 -0.3 -0.4 -1.6 0.4 -2.4 -1.9 -0.8 -0.8 -0.4 -1.2 -2.9 -2.4 -0.6 0.1 -0.7 -2.0 -1.3 -0.0 -1.6 -0.9 -0.7 -0.3 -0.7 -1.1 -1.7 -1.1
Frequency of depressed mood in last 2 weeks 0.2 0.2 0.7 0.4 0.7 0.4 0.7 0.8 0.2 0.6 0.5 0.6 0.0 0.4 0.6 0.8 0.4 0.6 0.4 0.5 0.6 0.5 0.5 0.7 0.2 0.4 0.6 0.5 0.7 0.6 -0.2 0.5 0.3 0.3 0.6 0.2 0.6 0.4 0.3 0.2 -0.3 0.7 0.6 -0.1 0.5 0.5 0.6 0.4 0.6 0.0 0.4
Hearing difficulty/problems: Yes 0.8 1.2 4.0 0.7 2.0 1.8 1.0 1.1 1.1 1.2 1.1 1.1 0.0 1.1 0.8 0.9 1.0 1.2 1.3 1.1 1.0 1.3 1.1 1.2 0.9 1.0 1.1 1.0 1.7 1.2 -0.1 1.0 1.0 0.8 1.1 0.2 1.3 0.9 1.0 0.8 -0.2 1.2 1.7 -0.5 1.9 0.9 1.6 1.0 0.8 0.6 0.2
Relative age of first facial hair 0.7 1.5 5.2 1.2 2.1 2.3 0.4 0.0 2.1 1.1 1.3 0.9 0.0 1.1 1.0 -0.1 1.3 0.4 1.4 1.0 1.0 1.5 0.7 1.2 1.6 1.7 1.3 0.4 1.7 0.5 -0.7 1.2 1.3 1.3 0.9 0.7 0.8 1.3 1.7 1.4 0.7 0.9 1.3 -0.1 1.3 1.4 1.1 1.3 1.7 0.8 0.8
Other serious medical condition/disability diagnosed by doctor 0.3 0.4 3.4 -0.1 0.5 0.1 -0.7 -0.8 1.4 0.1 0.5 -0.4 0.0 0.1 -0.0 -0.7 0.4 -0.6 0.3 -0.1 -0.3 -0.1 -0.5 -1.1 0.2 0.7 0.3 -0.4 1.8 -1.0 -0.4 -0.2 0.0 0.4 -0.4 -1.1 -1.0 0.2 0.6 1.2 -0.2 -0.4 0.8 -0.2 0.5 -0.0 -0.1 -0.0 -0.2 -0.1 0.2
Ever used hormone-replacement therapy (HRT) 0.0 0.0 0.5 0.0 -0.0 -0.0 -0.1 0.4 0.2 -0.1 -0.1 -0.1 0.0 -0.1 0.2 0.7 -0.0 0.0 0.0 -0.1 0.1 -0.4 0.0 0.1 -0.2 0.0 0.1 0.3 -0.4 -0.1 -0.1 -0.2 0.0 0.4 -0.0 -0.3 -0.3 0.1 0.1 0.3 0.0 0.1 0.3 -0.3 0.3 0.1 -0.1 0.1 -0.3 0.2 0.1
Ever had hysterectomy (womb removed) 0.2 0.2 1.3 -0.0 -0.8 -0.4 0.6 0.9 -0.6 0.2 -0.4 0.4 0.0 0.6 0.7 1.1 0.6 0.6 0.1 0.2 0.6 -0.5 0.6 0.4 0.1 0.1 -0.4 0.7 0.1 0.5 0.9 0.1 0.3 0.5 0.3 0.7 0.5 0.2 -0.1 -0.1 0.3 0.6 0.1 0.5 0.3 0.4 0.1 0.2 0.3 0.7 0.5
Systolic blood pressure, automated reading 0.3 0.9 3.6 -1.1 -1.7 -1.5 -0.5 -0.5 -0.1 -0.9 -1.1 -0.8 0.0 -0.2 -0.8 -0.5 -0.7 -0.4 -1.1 -0.9 -0.6 -1.1 -0.6 -0.7 -1.3 -0.8 -0.9 -0.5 -1.4 -0.3 -0.6 -0.7 -0.8 -0.8 -0.8 0.7 -0.2 -1.0 -1.1 -1.9 -0.2 -0.7 -1.8 -0.2 -1.7 -0.7 -1.2 -0.8 -0.6 -1.7 -0.6
Eye problems/disorders: Diabetes related eye disease 0.4 0.4 2.4 0.0 0.9 1.3 -0.0 -0.4 -0.2 0.2 -0.1 0.1 0.0 -0.4 0.4 -0.4 0.9 0.1 0.4 0.1 0.5 0.1 0.3 0.4 0.3 0.8 1.5 0.2 1.0 0.3 -0.2 0.1 0.9 0.9 0.0 1.1 0.7 0.7 0.8 1.1 0.8 0.3 0.5 1.1 0.1 0.7 0.7 0.5 0.8 0.2 1.0
Angina 1.9 2.5 5.8 -1.3 -1.3 -1.9 -2.0 -2.2 -1.6 -1.4 -0.7 -1.8 0.0 -1.9 -2.0 -2.4 -1.4 -1.9 -1.3 -1.7 -1.6 -1.3 -1.8 -2.2 -1.4 -0.9 -1.2 -1.9 -1.0 -2.1 -1.3 -1.7 -1.2 -0.8 -1.9 -2.0 -2.1 -1.1 -0.8 -0.9 -0.5 -1.9 -1.6 -1.5 -1.4 -1.3 -2.3 -1.3 -1.4 -1.5 -1.3
Medication for hormone replacement therapy 0.1 0.2 1.5 -0.1 -0.6 -0.6 0.3 0.6 -0.8 -0.2 -0.6 0.2 0.0 -0.1 0.4 0.7 0.0 0.4 0.1 0.1 0.2 -0.5 0.3 0.3 -0.1 -0.5 -0.3 0.5 -1.2 0.3 -0.2 -0.2 -0.2 -0.2 0.2 0.5 0.1 -0.2 -0.4 0.2 0.4 0.1 -0.2 0.6 -0.0 -0.1 -0.1 -0.2 -0.2 0.2 0.4
Vitamin and mineral supplements 0.1 0.2 0.8 -0.0 -0.7 -0.2 -0.4 -0.6 0.1 -0.1 0.2 -0.2 0.0 -0.5 -0.7 -0.8 -0.5 -0.5 -0.3 -0.2 -0.5 0.1 -0.5 0.0 0.3 -0.6 -0.6 -0.7 0.0 -0.0 0.0 0.4 -0.5 -0.4 -0.3 0.3 0.8 -0.3 -0.5 -0.9 0.4 -0.2 -0.7 0.1 -0.5 -0.4 -0.8 -0.3 -0.2 -0.2 -0.4
Supplements: Zinc 0.2 0.2 1.4 -0.4 0.1 0.4 0.6 0.9 -0.2 -0.4 -0.9 -0.1 0.0 0.2 0.5 1.2 0.6 0.4 -0.1 -0.3 0.4 -0.8 0.5 0.3 -0.3 0.1 -0.1 0.7 -0.1 0.3 0.3 -0.7 0.3 -0.3 -0.0 -0.1 -0.0 -0.2 -0.1 0.8 0.4 0.3 0.5 0.2 0.7 0.0 0.5 -0.3 0.0 0.7 0.3
Medication: Co-codamol 1.3 1.6 4.4 -1.0 0.0 -0.5 -1.8 -1.8 0.5 -1.3 -0.6 -1.6 0.0 -1.7 -1.5 -1.8 -1.1 -1.7 -1.3 -1.6 -1.1 -1.0 -1.6 -1.6 -1.0 -0.7 -0.8 -1.6 0.5 -1.8 -1.7 -1.0 -0.8 -0.5 -1.6 -1.0 -1.3 -0.7 -0.4 -0.8 -0.6 -1.4 -1.3 -1.8 -1.9 -0.7 -0.4 -0.6 -1.0 -2.1 -0.9
Medication: Metformin 1.6 2.2 4.9 -1.5 -1.6 -1.6 -1.9 -1.8 -1.6 -1.7 -1.2 -1.8 0.0 -1.9 -1.8 -1.8 -1.5 -1.8 -1.6 -1.8 -1.5 -1.2 -1.6 -1.9 -1.4 -1.1 -0.8 -1.7 -1.1 -1.5 -0.3 -1.4 -1.3 -0.8 -1.9 0.0 -0.9 -1.3 -1.2 -1.8 -0.6 -1.6 -2.2 -1.1 -2.2 -1.2 -1.8 -1.4 -0.9 -2.1 -1.3
Diabetes (father) 1.0 1.3 3.0 -0.8 -1.0 -1.6 -1.1 -0.9 0.6 -1.5 -1.0 -1.3 0.0 -0.9 -0.9 -0.7 -1.5 -1.2 -1.1 -1.2 -1.3 -0.9 -1.1 -1.1 -1.2 -1.3 -1.4 -1.0 -0.6 -0.7 -1.5 -0.9 -1.1 -1.1 -1.2 -0.3 -0.2 -1.3 -1.2 -1.4 -0.3 -1.1 -1.6 -0.1 -1.7 -1.2 -1.4 -1.3 -1.2 -1.6 -0.9
Diabetes (mother) 0.1 0.2 2.1 -0.4 0.1 0.0 -0.3 -0.3 0.9 -0.4 -0.5 -0.2 0.0 -0.1 0.0 -0.2 -0.1 -0.1 -0.2 -0.3 0.1 -0.1 -0.0 -0.3 -0.0 0.5 0.5 0.0 1.0 -0.3 1.2 -0.6 0.1 0.2 -0.3 0.4 0.1 0.0 0.2 0.1 -0.2 -0.1 -0.2 -1.4 0.0 0.2 0.1 -0.0 0.6 -0.2 -0.5
Severe depression (siblings) 0.2 0.3 1.6 -0.3 0.1 -0.3 0.2 0.2 -0.8 -0.2 -0.3 0.0 0.0 -1.0 -0.2 0.2 -0.8 0.2 -0.2 -0.1 -0.2 -0.2 0.1 0.2 -0.4 -1.3 -0.7 -0.1 -1.2 0.2 0.3 -0.2 -0.6 -0.9 -0.0 0.1 0.3 -0.6 -0.8 -0.4 -0.8 -0.1 -0.3 -0.2 -0.5 -0.5 0.7 -0.5 -0.5 -0.8 -0.1
Pack years adult smoking proportion 3.2 4.9 9.7 -1.8 -1.2 -1.9 -3.0 -2.8 -0.8 -2.4 -1.3 -2.9 0.0 -2.6 -2.4 -2.5 -2.1 -3.0 -2.4 -2.7 -2.6 -2.2 -2.9 -3.1 -2.3 -1.5 -1.8 -2.7 -0.5 -2.8 -2.1 -2.1 -1.9 -1.5 -2.8 -2.5 -2.1 -1.9 -1.5 -1.6 -1.5 -2.5 -1.8 -1.1 -2.8 -2.0 -1.9 -2.1 -2.7 -2.7 -1.9
Impedance of leg (right) 0.1 0.4 2.1 1.5 0.6 0.4 0.3 0.3 0.1 0.7 1.3 0.8 0.0 0.1 0.7 0.3 0.1 0.1 1.1 1.0 -0.0 0.9 0.1 0.6 0.4 -0.4 -0.7 -0.1 -0.4 -0.1 -1.0 1.2 -0.2 -0.3 0.9 -1.4 -0.3 0.2 0.2 0.3 0.9 0.2 0.8 0.8 0.9 0.1 -0.1 0.5 -0.0 0.6 0.3
Leg fat-free mass (left) 0.0 0.3 1.3 -0.0 0.4 -0.2 -0.1 -0.1 0.9 0.5 0.6 0.1 0.0 0.3 -0.0 -0.3 0.4 0.2 0.0 0.2 0.2 0.8 0.1 -0.5 0.5 0.7 0.8 0.0 1.1 0.5 1.2 0.2 0.4 0.6 0.1 1.1 1.0 0.4 0.4 0.3 -0.6 0.4 0.3 -0.4 0.1 0.4 0.7 0.3 0.5 -0.3 0.2
Trunk fat percentage 0.3 1.2 4.5 -0.6 -0.3 -1.6 -1.7 -1.6 1.1 -0.8 0.4 -1.2 0.0 -1.6 -1.0 -1.5 -0.9 -1.6 -0.7 -1.0 -1.2 -0.2 -1.6 -2.1 -1.5 -0.6 -0.5 -1.6 0.8 -1.4 -1.0 -0.9 -1.1 -0.2 -1.2 -0.6 -0.6 -0.7 -0.5 -0.7 -1.2 -1.1 -0.9 -1.0 -1.3 -0.7 -1.0 -0.7 -0.7 -2.0 -0.9
Hand grip strength (right) 0.6 1.8 4.4 1.3 1.8 1.2 1.2 1.2 1.3 1.3 1.3 1.5 0.0 1.8 1.0 1.1 1.2 1.2 1.6 1.6 1.1 2.1 1.3 1.0 2.0 1.1 1.1 1.2 1.3 1.4 0.9 1.6 1.0 1.0 1.5 0.6 1.6 1.0 1.1 1.7 0.7 1.3 2.0 0.6 2.0 1.1 1.3 1.1 1.1 1.4 1.0
Townsend deprivation index at recruitment 2.4 3.3 6.5 -1.7 -1.0 -1.4 -2.4 -2.4 -0.9 -1.7 -0.9 -2.2 0.0 -2.5 -1.8 -2.2 -1.7 -2.3 -1.7 -2.1 -2.1 -1.4 -2.3 -2.2 -1.8 -1.0 -1.0 -2.2 -0.7 -2.5 -1.4 -2.4 -1.6 -1.2 -2.3 -2.5 -2.4 -1.4 -1.1 -1.1 -1.6 -2.2 -1.6 -1.7 -1.9 -1.8 -1.7 -1.7 -2.0 -2.1 -1.8
Current tobacco smoking 3.6 5.9 24.3 -2.2 -1.2 -1.8 -2.4 -2.1 -1.9 -2.6 -1.8 -2.7 0.0 -3.2 -2.6 -1.8 -2.5 -2.6 -2.3 -2.6 -2.3 -2.5 -2.4 -2.7 -2.5 -1.8 -2.0 -2.1 -0.5 -3.8 -3.1 -2.8 -2.5 -2.0 -2.7 -3.9 -4.9 -2.2 -1.8 -0.7 -2.9 -3.0 -1.4 -2.8 -1.9 -2.5 -2.0 -2.2 -2.7 -1.3 -2.1
Average weekly fortified wine intake 0.3 0.3 0.9 -1.0 -0.6 -0.6 0.1 0.3 -0.0 -0.7 -1.0 -0.4 0.0 -0.3 -0.2 0.5 -0.4 0.1 -0.7 -0.5 -0.3 -0.5 -0.1 -0.4 -0.4 -0.7 -0.6 0.0 -0.6 -0.1 -0.6 -0.4 -0.6 -0.8 -0.5 -0.4 -0.5 -0.7 -0.9 -0.7 -0.9 -0.4 -0.6 -0.9 -0.5 -0.7 -0.3 -0.8 -0.4 -0.5 -0.7
Maternal smoking around birth 1.1 1.7 11.4 -1.3 -0.6 -1.3 -1.6 -1.5 0.6 -1.4 -0.8 -1.6 0.0 -1.9 -1.6 -1.4 -0.9 -1.5 -1.3 -1.5 -1.0 -1.2 -1.3 -1.8 -1.0 0.3 -0.4 -1.1 -0.2 -2.5 -0.9 -2.0 -0.5 -0.5 -1.6 -1.8 -3.4 -0.6 -0.2 0.0 -0.2 -1.7 -1.1 -1.0 -1.4 -1.0 -1.4 -0.9 -0.6 -0.2 -0.5
Fed-up feelings 0.1 0.2 1.8 0.3 -0.1 -0.6 0.6 0.7 0.5 0.7 0.5 0.6 0.0 0.1 0.3 0.5 -0.2 0.7 0.5 0.7 0.3 0.5 0.4 0.1 0.5 0.1 0.0 0.4 0.5 0.4 0.0 0.7 0.3 0.0 0.6 -0.2 -0.0 0.3 0.1 0.1 0.0 0.4 0.4 1.3 -0.2 0.2 0.4 0.3 0.1 0.2 1.0
Frequency of unenthusiasm / disinterest in last 2 weeks 0.5 0.7 2.1 1.0 1.1 0.4 0.5 0.5 0.2 1.3 1.3 0.9 0.0 0.9 0.5 0.3 0.6 0.5 1.0 1.1 0.5 1.4 0.5 0.8 1.1 0.5 0.9 0.3 0.8 0.7 0.8 1.3 0.5 0.8 0.9 0.1 1.1 0.9 0.7 1.0 0.2 0.9 1.3 1.0 0.8 0.8 0.7 0.9 0.6 0.5 0.9
Relative age voice broke 1.4 2.2 11.0 1.8 2.5 3.0 0.6 0.4 3.3 1.6 2.0 1.3 0.0 1.3 1.7 0.5 1.4 0.5 1.8 1.4 1.0 1.8 0.7 1.9 1.4 1.5 1.5 0.5 1.7 1.0 -1.1 1.6 1.2 1.3 1.3 1.0 1.6 1.4 1.8 1.3 0.4 1.3 1.7 0.1 1.5 1.5 1.9 1.5 1.5 0.3 0.9
Taking other prescription medications 2.2 3.5 8.3 -1.6 -1.5 -1.8 -2.1 -1.9 -0.2 -2.0 -1.3 -2.1 0.0 -2.1 -1.5 -1.7 -1.8 -2.0 -1.8 -2.1 -1.9 -1.8 -2.0 -2.4 -2.3 -1.4 -1.8 -1.9 -1.1 -2.4 -2.9 -2.1 -1.8 -1.6 -2.1 -2.2 -2.5 -1.8 -1.5 -1.7 -1.4 -2.1 -1.8 -1.5 -1.9 -1.8 -1.9 -1.8 -1.9 -1.8 -1.8
Age when periods started (menarche) 0.2 0.4 4.4 0.6 1.3 2.1 -0.8 -0.8 0.6 -0.2 0.4 -0.4 0.0 -0.4 -0.3 -0.7 -0.2 -1.0 0.1 -0.2 -0.3 0.1 -0.6 0.2 0.1 0.6 0.6 -0.6 0.6 -1.0 -1.5 0.4 0.3 0.4 -0.4 -1.3 -0.7 0.3 0.8 0.1 0.1 -0.3 0.3 -0.1 -0.3 0.3 0.6 0.2 0.3 -0.5 -0.3
Bilateral oophorectomy (both ovaries removed) 0.1 0.1 0.8 0.3 -0.1 -0.9 -0.2 -0.1 0.4 0.3 0.4 0.0 0.0 0.3 0.3 -0.0 0.5 -0.1 0.1 0.0 0.3 0.2 0.1 -0.4 -0.2 0.3 0.4 0.1 0.7 -0.1 0.5 0.0 0.2 0.8 0.0 0.3 -0.2 0.5 0.4 0.3 -0.1 0.2 0.3 0.6 -0.1 0.5 0.3 0.3 0.3 -0.3 0.7
Heel bone mineral density (BMD) T-score, automated (left) 0.5 1.0 4.1 -0.9 -1.8 -2.0 0.1 -0.1 -1.8 -0.9 -1.2 -0.6 0.0 -0.7 -0.7 -0.2 -0.9 0.0 -0.8 -0.6 -0.8 -0.9 -0.3 -0.8 -1.1 -1.4 -1.5 -0.2 -1.8 -0.4 -0.2 -1.1 -1.2 -1.4 -0.5 -0.9 -1.0 -1.3 -1.5 -1.1 -0.8 -0.9 -1.0 -0.6 -0.6 -1.2 -1.3 -1.1 -0.9 -0.6 -0.8
Tinnitus: Yes, but not now, but have in the past 0.3 0.3 6.1 0.7 0.6 0.5 -0.4 -0.5 2.5 0.6 1.3 0.3 0.0 0.1 0.2 -0.6 0.3 -0.3 0.5 0.5 -0.6 0.9 -0.5 0.2 0.2 -0.1 0.1 -0.6 0.0 0.0 -1.0 0.5 -0.3 -0.1 0.2 0.1 0.6 0.2 0.2 -0.2 0.5 -0.1 -0.0 -0.3 0.2 -0.2 -0.2 0.1 0.1 -0.4 -0.3
Qualifications: CSEs or equivalent 0.4 0.6 2.4 0.3 0.4 0.2 1.2 1.5 0.1 0.6 0.0 1.0 0.0 0.7 0.6 1.3 -0.3 1.2 0.5 0.9 0.6 0.5 0.9 0.6 0.0 -0.5 -0.3 0.8 0.4 1.4 0.4 0.8 0.0 -0.1 0.9 -1.0 1.2 0.1 -0.4 -0.0 -0.7 0.9 1.2 -0.2 1.6 0.1 0.8 0.1 0.1 0.8 -0.3
Serious illness, injury or assault to yourself 0.4 0.4 3.0 0.4 0.9 0.5 -0.9 -0.7 1.1 0.3 1.0 -0.2 0.0 -0.3 0.1 -0.5 0.2 -0.8 0.5 0.1 -0.7 0.6 -1.0 -0.6 -0.1 -0.1 0.2 -0.8 0.9 -1.2 -1.7 0.4 -0.4 0.0 -0.3 -1.7 -0.9 0.1 0.3 0.4 -0.7 -0.4 1.0 0.1 0.4 -0.2 0.4 0.1 -0.3 -0.5 -0.3
High blood pressure 0.7 2.0 10.0 -1.4 -2.8 -3.2 -0.4 -0.1 -1.3 -1.6 -1.9 -1.1 0.0 -1.0 -0.8 0.1 -1.7 -0.3 -1.5 -1.3 -0.8 -1.8 -0.5 -1.7 -2.0 -1.6 -1.4 -0.3 -1.5 -0.5 -1.1 -1.4 -1.5 -1.5 -1.0 0.4 -0.7 -1.6 -2.0 -1.7 -0.7 -1.0 -2.3 -0.4 -2.0 -1.3 -1.6 -1.4 -1.3 -1.2 -0.7
Hayfever, allergic rhinitis or eczema 0.1 0.2 0.9 0.3 -0.3 -0.1 -0.9 -1.0 -0.1 -0.5 -0.1 -0.6 0.0 -0.0 -0.1 -0.8 0.0 -1.0 -0.4 -0.5 -0.7 -0.2 -0.8 -0.5 -0.4 -0.2 -0.5 -0.8 -0.7 -0.8 0.4 -0.2 -0.4 0.0 -0.5 0.5 -0.1 -0.2 -0.2 -0.4 0.1 -0.6 -0.7 0.2 -0.8 -0.2 -0.5 -0.2 -0.1 -0.5 -0.2
Multivitamins +/- minerals 0.1 0.1 1.1 0.0 0.8 0.3 -0.3 0.1 1.0 -0.1 0.1 -0.1 0.0 0.8 0.0 0.2 -0.1 -0.3 0.0 -0.1 -0.2 0.0 -0.3 -0.1 -0.6 0.1 -0.0 -0.1 0.2 -0.0 -0.6 -0.1 -0.1 -0.1 -0.1 -0.7 0.3 -0.1 0.1 0.0 -0.6 0.1 0.5 -0.7 0.3 -0.1 0.4 -0.1 -0.4 -0.9 -0.5
Stomach or abdominal pain in last month 1.4 1.8 5.2 0.6 1.7 2.3 1.3 1.3 0.6 1.3 0.6 1.3 0.0 1.2 1.1 1.2 1.5 1.3 1.3 1.2 1.5 0.8 1.4 1.2 1.7 1.5 1.8 1.5 1.4 1.2 1.4 1.0 1.6 1.2 1.2 0.5 0.9 1.5 1.5 1.6 0.8 1.4 1.8 0.7 1.6 1.3 1.9 1.4 1.3 1.2 1.2
Supplements: Glucosamine 0.4 0.5 3.0 0.7 0.5 -0.0 0.8 1.3 0.6 0.6 0.5 0.7 0.0 1.2 0.8 1.4 0.4 0.8 0.5 0.7 0.5 0.6 0.7 0.3 0.3 0.2 0.1 0.9 0.5 1.2 1.7 0.6 0.4 -0.0 0.8 0.2 1.6 0.1 0.2 0.2 0.4 1.1 0.9 0.6 1.1 0.4 0.7 0.3 0.3 0.3 0.2
Diverticular disease/diverticulitis (self-reported) 0.9 1.0 5.9 0.9 0.8 -0.5 -1.4 -1.3 2.1 0.2 2.0 -0.3 0.0 -0.3 -0.6 -1.5 -1.0 -1.2 0.1 0.1 -1.4 0.9 -1.5 -0.9 -0.6 -0.5 -0.8 -1.7 -0.1 -0.8 -2.4 0.3 -1.1 -0.5 -0.3 -1.8 0.2 -0.5 -0.3 -1.1 -0.5 -0.7 -0.1 -0.5 -0.2 -0.7 -1.0 -0.3 -0.9 -1.6 -1.1
Medication: Atenolol 2.2 2.7 6.7 -2.0 -1.8 -1.3 -1.0 -0.9 -2.6 -1.9 -2.1 -1.6 0.0 -1.2 -2.0 -1.0 -1.6 -1.1 -1.9 -1.7 -1.5 -2.1 -1.3 -1.3 -1.7 -1.9 -1.7 -1.2 -1.8 -0.9 -0.4 -1.8 -1.9 -1.8 -1.7 -1.7 -0.6 -1.9 -2.1 -1.4 -1.4 -1.5 -1.6 -2.6 -1.1 -1.9 -1.4 -1.9 -2.3 -1.5 -2.1
Medication: Levothyroxine sodium 0.5 0.9 3.0 -0.5 -1.0 -1.1 -1.2 -1.2 1.0 -0.9 -0.4 -1.0 0.0 -0.6 -0.7 -1.2 -0.5 -1.3 -0.9 -1.1 -0.9 -0.6 -1.1 -0.9 -0.7 -0.6 -0.8 -1.2 -0.3 -1.3 -1.7 -0.9 -1.0 -0.8 -1.0 -0.5 -1.2 -0.9 -0.7 -1.1 -0.6 -1.1 -1.2 -0.8 -1.1 -0.9 -1.4 -0.9 -1.0 -1.2 -0.8
Sitting height 0.3 2.3 5.0 1.8 2.1 2.1 0.7 0.6 1.5 1.7 1.8 1.4 0.0 1.1 1.3 0.5 1.9 0.7 1.6 1.5 1.2 2.1 1.1 1.2 2.2 2.0 2.1 1.0 1.7 0.6 1.2 1.7 1.6 1.6 1.4 0.5 0.5 1.7 2.1 1.6 0.7 1.2 2.0 0.4 1.7 1.6 2.0 1.6 1.8 1.4 1.2
Chronic bronchitis/emphysema (father) 0.6 0.7 6.7 -1.1 -0.8 -0.7 -0.4 -0.5 -1.0 -0.9 -1.2 -0.8 0.0 -1.0 -0.5 -0.3 -0.2 -0.3 -0.7 -0.9 -0.3 -0.9 -0.3 -0.9 -0.8 0.0 -0.3 -0.2 0.6 -1.4 0.1 -1.4 -0.5 -0.4 -0.8 -0.8 -2.6 -0.5 -0.4 0.4 -1.5 -1.0 -0.4 -1.3 -0.6 -0.6 -0.3 -0.6 -0.5 -0.0 -0.4
High blood pressure (mother) 0.2 0.3 1.6 -0.5 -0.9 -0.1 -0.4 -0.4 -1.3 -0.8 -0.9 -0.4 0.0 0.1 -0.0 -0.1 -0.2 -0.5 -0.5 -0.4 -0.5 -0.8 -0.3 -0.2 -0.8 -0.7 -0.9 -0.2 -0.7 -0.5 0.6 -0.4 -0.5 -0.8 -0.5 0.1 -0.2 -0.7 -0.6 -0.8 0.2 -0.6 -0.9 -0.5 -0.7 -0.6 -0.6 -0.6 -0.4 -0.6 -0.5
Body mass index (BMI) 0.2 0.8 4.1 -0.6 -0.3 -1.6 -1.4 -1.3 1.5 -0.5 0.2 -1.0 0.0 -1.1 -0.7 -1.3 -0.4 -1.2 -0.7 -0.9 -0.8 -0.2 -1.2 -2.0 -1.1 -0.1 -0.2 -1.2 0.6 -0.8 -0.2 -0.9 -0.6 0.2 -1.0 0.1 -0.1 -0.3 -0.2 -0.4 -1.0 -0.7 -0.8 -0.6 -1.3 -0.4 -0.4 -0.4 -0.5 -1.6 -0.4
Impedance of leg (left) 0.2 0.8 2.1 1.5 1.0 1.0 1.0 0.9 0.0 1.0 1.1 1.2 0.0 0.3 1.1 1.0 0.6 0.7 1.4 1.2 0.7 1.1 0.8 1.2 0.8 0.3 -0.0 0.7 0.3 0.2 -1.1 1.3 0.5 0.3 1.2 -1.0 -0.5 0.7 0.7 1.0 1.1 0.7 1.3 1.2 1.4 0.7 0.4 0.9 0.6 1.3 0.9
Leg predicted mass (left) 0.0 0.2 1.2 -0.1 0.3 -0.4 -0.2 -0.3 0.8 0.3 0.5 -0.0 0.0 0.2 -0.2 -0.4 0.2 -0.0 -0.1 0.0 0.0 0.8 -0.1 -0.7 0.4 0.6 0.7 -0.1 1.0 0.3 1.1 0.1 0.2 0.5 -0.1 1.0 0.9 0.3 0.3 0.2 -0.7 0.2 0.1 -0.5 -0.1 0.2 0.5 0.2 0.4 -0.5 0.1
Trunk fat mass 0.2 1.0 4.4 -0.5 -0.2 -1.6 -1.6 -1.5 1.5 -0.5 0.6 -1.1 0.0 -1.4 -0.9 -1.5 -0.8 -1.4 -0.7 -0.8 -1.1 0.1 -1.5 -2.1 -1.2 -0.5 -0.3 -1.5 0.9 -1.2 -0.7 -0.7 -1.0 -0.0 -1.0 -0.4 -0.4 -0.5 -0.3 -0.5 -1.4 -0.9 -0.7 -1.0 -1.2 -0.6 -0.7 -0.5 -0.6 -1.9 -0.7
Waist circumference 0.2 0.9 4.0 -0.5 -0.1 -1.2 -1.4 -1.4 1.3 -0.7 0.0 -1.1 0.0 -1.3 -0.8 -1.3 -0.6 -1.2 -0.6 -1.0 -0.8 -0.3 -1.2 -2.0 -1.3 -0.3 -0.3 -1.3 0.7 -0.9 -0.9 -0.9 -0.8 0.1 -1.1 0.0 -0.3 -0.4 -0.3 -0.4 -1.5 -0.8 -0.7 -1.0 -1.2 -0.4 -0.3 -0.5 -0.6 -1.8 -0.6
Number of incorrect matches in round 2.0 3.4 5.6 2.1 1.5 1.1 1.9 2.2 1.2 2.3 1.8 2.2 0.0 2.2 2.1 2.2 2.1 1.8 2.0 2.2 1.9 2.0 1.8 2.0 1.7 1.4 1.3 1.7 1.6 2.1 1.0 2.1 1.7 1.5 2.2 1.1 2.3 1.8 1.6 1.0 1.7 2.4 1.8 1.4 2.1 1.9 1.7 2.0 1.8 1.8 1.4
Past tobacco smoking 2.3 4.3 19.0 1.6 1.0 1.4 2.7 2.8 0.2 1.8 0.6 2.5 0.0 2.8 2.3 2.6 1.5 2.8 2.0 2.4 1.9 1.9 2.4 2.9 1.7 0.5 1.2 2.4 1.1 3.8 0.8 2.8 1.5 0.8 2.5 2.9 4.4 1.1 0.5 1.0 1.8 2.6 1.6 2.7 2.0 1.6 2.0 1.3 1.4 1.9 1.7
Alcohol usually taken with meals 1.5 2.5 11.9 0.9 0.6 1.1 2.3 2.5 -0.4 1.3 0.3 1.8 0.0 2.1 1.6 2.4 1.1 2.3 1.2 1.7 1.6 0.9 2.0 1.8 0.6 0.5 0.7 2.1 0.6 3.1 1.9 1.8 1.3 0.6 1.8 1.8 3.4 0.8 0.4 0.4 1.1 2.1 1.4 1.5 1.8 1.2 1.7 1.1 1.0 1.1 0.9
Nervous feelings 0.6 1.1 5.2 -0.7 -0.8 -0.5 -0.3 -0.1 -1.4 -0.8 -1.2 -0.7 0.0 -1.6 -0.7 -0.1 -1.4 -0.4 -1.0 -0.8 -0.6 -1.2 -0.4 -0.7 -1.3 -0.9 -1.1 -0.3 -0.9 -1.3 -1.4 -1.1 -0.9 -0.8 -0.7 -2.0 -2.3 -1.0 -0.8 -0.8 -2.3 -0.9 -0.4 -1.1 -0.7 -0.9 -0.7 -1.0 -1.0 -0.6 -0.8
Frequency of tenseness / restlessness in last 2 weeks 0.3 0.5 4.2 -0.5 -0.7 -0.7 0.9 1.1 -0.4 -0.1 -1.0 0.3 0.0 0.1 -0.4 0.7 -0.9 0.9 -0.3 0.1 0.1 -0.3 0.5 0.3 -0.7 -1.1 -0.8 0.5 -0.3 0.8 -1.3 -0.0 -0.8 -0.9 0.3 -0.4 0.2 -0.9 -1.2 -0.3 -2.0 0.1 0.3 -0.3 0.2 -0.6 0.3 -0.7 -0.9 -0.1 -0.2
Hearing difficulty/problems with background noise 0.4 0.6 3.0 1.1 1.7 0.8 0.5 0.5 1.2 1.1 1.3 1.0 0.0 -0.2 0.6 0.2 0.2 0.6 1.1 1.0 0.4 1.2 0.5 0.5 0.1 0.0 0.2 0.2 0.4 0.4 -0.3 0.9 0.4 0.3 1.0 -0.9 0.3 0.6 0.6 0.5 -0.9 0.6 1.6 0.1 1.3 0.4 1.2 0.8 0.3 0.3 0.2
Hair/balding pattern: Pattern 2 1.4 1.7 5.0 -0.6 -1.1 -1.4 -1.1 -1.2 -0.2 -0.6 0.3 -0.7 0.0 -1.3 -1.2 -1.5 -1.1 -1.2 -0.7 -0.6 -1.7 -0.4 -1.5 -1.3 -1.1 -1.9 -2.1 -1.7 -2.2 -1.1 -0.9 -0.5 -2.0 -1.6 -0.9 -1.8 -0.8 -1.5 -1.7 -1.5 -1.9 -1.4 -0.7 -1.0 -0.9 -1.7 -1.3 -1.4 -1.8 -1.5 -1.3
Had menopause 0.3 0.4 1.6 0.8 0.5 0.4 0.3 0.7 1.1 0.6 0.8 0.6 0.0 0.9 0.6 0.8 0.4 0.4 0.7 0.6 0.3 0.6 0.2 0.5 0.2 0.2 0.3 0.3 0.4 0.7 -1.3 0.8 0.3 0.4 0.6 0.0 1.2 0.5 0.3 -0.2 0.6 0.7 0.7 0.7 0.6 0.5 0.8 0.6 0.0 0.3 0.4
Had other major operations 0.5 0.7 1.4 -0.9 -0.9 -0.5 -1.0 -0.8 -0.5 -0.8 -0.7 -1.2 0.0 -1.1 -0.4 -0.4 -0.5 -1.0 -1.0 -1.0 -1.0 -0.9 -1.1 -1.1 -0.5 -1.0 -1.2 -0.7 -1.0 -0.6 -0.4 -0.7 -0.7 -0.5 -1.1 -0.7 -0.0 -0.7 -0.7 -0.8 -0.0 -0.7 -0.8 -0.0 -0.9 -0.7 -1.2 -0.9 -0.9 -1.0 -0.7
Forced vital capacity (FVC) 1.0 3.9 10.1 1.9 1.5 1.4 2.7 2.5 1.4 2.3 1.4 2.7 0.0 2.5 1.9 2.0 1.6 2.6 2.3 2.7 1.9 2.4 2.4 2.4 2.3 0.8 1.0 2.1 0.7 3.1 1.0 2.5 1.3 0.7 2.7 1.2 3.0 1.4 1.0 1.0 1.1 2.3 2.4 0.9 3.2 1.4 2.1 1.5 1.7 2.0 1.2
Heel bone mineral density (BMD) T-score, automated (right) 1.2 2.7 6.5 -1.0 -1.8 -2.4 -1.0 -1.1 -2.1 -1.5 -1.0 -1.3 0.0 -1.8 -1.5 -1.3 -1.7 -1.1 -1.4 -1.3 -1.8 -1.2 -1.4 -1.8 -1.7 -2.3 -2.5 -1.5 -2.5 -1.1 -1.1 -1.3 -2.0 -2.0 -1.2 -1.8 -1.0 -1.9 -2.1 -1.9 -1.3 -1.6 -1.5 -1.2 -1.3 -1.9 -1.9 -1.8 -1.7 -1.7 -1.7
Ever unenthusiastic/disinterested for a whole week 0.4 0.5 2.0 -1.0 -0.1 0.0 -0.9 -0.8 -0.6 -0.6 -0.5 -1.0 0.0 -1.0 -0.9 -0.8 -0.5 -0.9 -0.7 -0.9 -0.7 -0.9 -0.9 -0.5 -0.5 -0.3 -0.2 -0.8 -0.4 -0.9 -1.2 -0.9 -0.5 -0.4 -1.0 -0.3 -0.3 -0.5 -0.3 -0.3 -0.6 -0.6 -0.7 -1.4 -0.8 -0.5 -0.6 -0.8 -0.3 -1.1 -0.8
Qualifications: None of the above 1.8 3.8 10.0 -1.4 -2.2 -3.2 -1.8 -1.4 -2.2 -1.7 -1.0 -1.9 0.0 -2.7 -2.1 -1.3 -2.0 -1.8 -1.8 -1.9 -1.9 -1.8 -2.0 -2.5 -1.5 -1.7 -2.0 -1.8 -1.9 -2.5 -1.8 -1.6 -2.0 -1.3 -1.9 -1.0 -3.0 -1.7 -1.7 -1.8 -2.4 -2.1 -2.3 -1.0 -2.8 -2.0 -2.2 -1.8 -1.9 -2.1 -1.2
Financial difficulties in last 2 years 0.4 0.6 3.8 0.5 2.0 1.3 0.2 -0.0 1.7 0.7 0.9 0.4 0.0 0.0 0.7 0.1 1.1 0.1 0.7 0.5 0.5 0.8 0.2 0.4 0.8 1.0 0.9 -0.0 0.1 0.2 -1.3 0.5 0.6 0.7 0.4 0.5 0.2 0.8 0.9 0.9 -1.0 0.4 0.9 -1.1 0.6 0.6 1.4 0.7 0.7 0.0 0.1
Mouth/teeth dental problems 5.9 9.1 18.6 2.8 1.8 2.5 3.3 3.5 1.6 3.0 2.0 3.5 0.0 3.6 3.1 3.3 2.6 3.4 3.0 3.4 3.1 3.0 3.3 3.7 3.2 1.8 2.8 3.2 1.5 4.1 4.1 3.2 2.7 2.2 3.6 3.6 4.3 2.6 2.0 2.4 2.9 3.6 2.7 3.2 3.1 2.9 3.0 2.8 2.8 3.5 2.9
Heart attack 0.6 0.8 6.1 0.6 -0.2 -1.4 -1.2 -1.1 1.0 0.1 1.4 -0.4 0.0 -1.0 -0.8 -1.3 -0.5 -1.2 0.3 -0.1 -0.9 0.3 -1.2 -1.3 -0.5 -0.5 -0.6 -1.3 -0.3 -1.5 -2.5 -0.1 -0.8 -0.1 -0.4 -1.8 -1.6 -0.0 -0.0 -0.5 0.0 -0.8 -0.2 0.1 -0.4 -0.5 -0.8 -0.1 -0.7 -0.6 -0.4
Allergy 1.3 3.1 5.8 1.3 2.1 1.9 2.0 1.9 0.6 2.0 1.4 2.0 0.0 1.4 1.5 1.7 1.5 2.0 2.0 2.0 2.0 1.7 2.0 2.1 2.0 1.7 1.9 1.9 1.9 2.1 1.0 1.8 1.9 1.6 1.9 0.8 1.8 1.7 1.7 1.9 1.0 2.0 2.3 0.9 2.4 1.7 1.8 1.8 1.5 1.7 1.5
Pain all over the body in last month 1.3 1.4 6.4 -1.5 -1.7 -1.5 -0.5 -0.4 -2.5 -1.3 -1.6 -1.2 0.0 -1.6 -0.6 -0.1 -1.1 -0.5 -1.6 -1.3 -0.6 -2.0 -0.7 -0.9 -1.2 -1.2 -1.3 -0.5 -1.5 -0.7 0.9 -1.4 -0.9 -0.8 -1.2 -0.0 -0.9 -1.1 -1.2 -1.3 -0.9 -0.9 -1.6 -0.9 -1.6 -0.9 -1.3 -1.1 -0.6 -0.8 -0.8
Diabetes (self-reported) 0.9 1.4 4.5 -0.9 -1.1 -1.7 -1.7 -1.8 -1.1 -0.9 -0.2 -1.2 0.0 -1.8 -1.6 -2.0 -1.3 -1.4 -1.0 -1.1 -1.2 -0.4 -1.5 -1.8 -0.7 -0.7 -0.1 -1.6 -0.8 -1.3 -0.4 -0.9 -0.9 -0.4 -1.3 0.1 -0.7 -0.7 -0.6 -1.5 -0.2 -1.3 -1.9 -0.1 -2.1 -0.8 -1.4 -0.9 -0.5 -1.9 -0.7
Hayfever/allergic rhinitis (self-reported) 0.9 1.1 4.5 -0.3 -0.5 -0.7 -1.6 -2.0 1.4 -0.9 0.1 -1.3 0.0 -0.4 -1.1 -2.1 -0.6 -1.5 -1.0 -1.1 -1.4 -0.6 -1.6 -1.3 -1.0 -0.5 -0.7 -1.6 -0.9 -1.3 -0.3 -1.1 -1.1 -0.4 -1.1 0.0 -0.6 -0.8 -0.5 -0.9 -0.7 -1.3 -1.2 -0.7 -1.2 -0.8 -1.4 -0.8 -0.9 -1.3 -1.0
Medication: Ramipril 0.1 0.1 0.7 0.4 -0.0 -0.7 -0.3 -0.2 -0.1 0.2 0.5 0.0 0.0 -0.5 0.1 -0.3 0.0 -0.2 0.0 -0.0 0.1 0.3 -0.1 -0.3 -0.1 -0.4 0.2 -0.3 0.0 -0.3 -0.9 0.0 -0.2 0.2 0.0 0.3 0.1 0.2 0.1 -0.3 -0.4 0.1 -0.1 -0.2 -0.1 0.2 0.1 0.2 0.1 -0.5 -0.2
Medication: Simvastatin 1.0 1.5 3.5 1.2 0.2 0.1 1.2 1.3 0.8 1.2 0.8 1.3 0.0 0.9 1.6 1.3 0.9 1.4 1.2 1.2 1.6 1.1 1.5 0.7 1.0 1.0 1.1 1.4 0.7 1.1 1.9 1.0 1.2 1.5 1.4 1.3 0.7 1.4 1.1 1.5 1.3 1.4 1.0 1.6 1.0 1.4 0.9 1.3 1.2 1.2 1.8
Fluid intelligence score 0.1 0.2 1.0 -0.2 -1.0 -0.4 -0.2 -0.4 -0.3 0.2 0.2 -0.0 0.0 0.2 0.0 -0.4 0.2 -0.2 0.0 0.1 -0.3 0.4 -0.3 -0.1 0.4 -0.0 -0.1 -0.2 -0.6 -0.6 0.9 0.4 -0.3 -0.4 -0.1 0.6 -0.7 0.0 -0.2 -0.6 0.7 -0.4 -1.0 0.2 -0.8 -0.2 -0.6 -0.0 0.3 -0.2 0.2
Illnesses of siblings 0.9 1.3 2.7 0.7 1.1 1.2 1.0 0.9 -0.6 1.2 0.6 1.0 0.0 1.3 0.6 0.8 1.5 0.9 1.1 1.1 1.2 1.1 1.1 1.1 1.4 1.6 1.2 1.1 1.6 1.2 1.3 0.9 1.4 1.3 1.0 1.0 1.3 1.2 1.3 1.3 1.6 1.3 1.2 1.0 1.5 1.2 0.6 1.0 1.2 1.5 1.0
Neuroticism score 0.6 1.2 5.2 -0.7 -0.7 -1.1 -0.9 -0.6 -0.1 -0.7 -0.7 -0.9 0.0 -1.6 -1.0 -0.6 -1.6 -0.8 -0.9 -0.8 -1.1 -0.8 -1.0 -1.6 -1.0 -1.1 -1.4 -0.9 -1.1 -1.3 -0.9 -1.0 -1.2 -0.9 -0.8 -1.9 -1.8 -1.0 -1.0 -0.9 -2.3 -1.0 -0.6 -0.9 -1.2 -1.1 -0.7 -1.0 -1.4 -1.3 -0.7
Weight 0.1 0.4 2.8 0.1 0.4 -0.9 -1.0 -1.0 1.7 0.2 1.0 -0.4 0.0 -0.6 -0.4 -1.1 -0.0 -0.8 -0.1 -0.2 -0.4 0.8 -0.8 -1.5 -0.3 0.4 0.4 -0.9 1.2 -0.4 -0.1 0.0 -0.2 0.5 -0.4 0.2 0.3 0.2 0.4 0.0 -0.8 -0.2 -0.1 -0.5 -0.5 0.1 0.2 0.1 0.1 -1.2 -0.1
Impedance of arm (right) 0.1 0.6 2.1 -0.4 -0.7 0.0 -0.3 -0.2 -1.4 -0.7 -0.3 -0.5 0.0 -0.7 -0.6 -0.2 -1.0 -0.5 -0.5 -0.5 -0.9 -0.8 -0.6 0.2 -0.8 -1.2 -1.4 -0.5 -1.1 -0.6 -0.5 -0.3 -1.0 -1.2 -0.5 -1.4 -0.6 -1.0 -1.0 -0.8 0.2 -0.7 -0.7 -0.5 -0.2 -1.0 -1.1 -0.9 -0.8 -0.3 -0.9
Arm fat percentage (right) 0.5 2.0 6.3 -1.2 -0.9 -2.2 -1.9 -1.7 1.1 -1.2 -0.2 -1.7 0.0 -1.8 -1.3 -1.5 -1.4 -1.7 -1.4 -1.5 -1.6 -0.8 -1.9 -2.5 -2.1 -1.0 -1.1 -1.8 -0.0 -1.5 -0.5 -1.6 -1.5 -0.6 -1.6 -0.8 -0.8 -1.1 -1.1 -1.0 -1.5 -1.4 -1.5 -1.2 -1.9 -1.2 -1.3 -1.2 -1.3 -2.2 -1.2
Trunk fat-free mass 0.1 0.5 2.1 0.7 0.6 -0.2 0.2 0.0 1.4 1.0 1.0 0.6 0.0 0.7 0.2 -0.3 0.7 0.4 0.5 0.7 0.5 1.5 0.3 -0.3 1.0 1.0 1.1 0.2 1.1 0.6 0.6 0.9 0.6 0.8 0.6 1.2 0.9 0.8 0.8 0.7 -0.4 0.6 0.7 0.2 0.3 0.7 1.0 0.7 0.9 0.2 0.8
Hip circumference 0.1 0.2 1.9 0.3 0.2 -0.8 -0.3 -0.3 1.4 0.4 0.9 0.1 0.0 -0.3 0.1 -0.3 0.2 -0.2 0.2 0.2 0.1 0.9 -0.2 -0.8 0.2 0.5 0.6 -0.2 1.0 0.1 -0.3 0.3 0.3 0.8 0.0 0.8 0.6 0.5 0.5 0.3 0.1 0.3 -0.1 0.3 -0.4 0.4 0.3 0.4 0.5 -0.6 0.6
Time employed in main current job 0.2 0.2 0.8 0.7 0.9 0.8 -0.7 -0.6 0.6 0.2 0.9 -0.1 0.0 -0.4 0.3 -0.5 0.1 -0.7 0.1 0.0 -0.2 0.4 -0.5 -0.1 0.5 0.1 0.1 -0.6 0.1 -0.3 0.9 0.3 0.1 0.5 -0.0 0.1 0.3 0.3 0.6 0.2 -0.1 0.0 0.3 -0.0 -0.2 0.3 0.5 0.4 0.2 -0.5 0.2
Alcohol intake versus 10 years previously 5.3 7.9 27.3 -2.7 -2.0 -2.5 -2.9 -3.1 -2.6 -2.8 -2.0 -3.2 0.0 -3.7 -3.1 -3.1 -2.8 -2.8 -2.9 -3.2 -2.7 -2.5 -2.8 -3.3 -2.5 -1.3 -2.1 -2.7 -2.0 -4.1 -2.7 -3.4 -2.4 -2.0 -3.2 -2.5 -5.2 -2.5 -1.9 -1.1 -3.1 -3.6 -2.9 -2.7 -3.6 -2.9 -2.7 -2.8 -2.5 -2.4 -1.9
Father’s age at death 0.6 0.8 6.0 1.3 0.2 0.5 0.8 0.6 1.3 1.2 1.1 1.1 0.0 1.7 0.7 0.1 0.4 0.7 0.9 1.2 0.3 1.6 0.4 1.4 0.6 -0.5 0.2 0.1 -0.1 1.7 -0.6 2.1 -0.1 -0.1 1.2 0.9 2.4 0.3 -0.2 -1.1 0.3 1.0 0.3 0.8 0.7 0.4 0.3 0.6 0.2 -0.8 -0.0
Worrier / anxious feelings 0.3 0.5 3.2 -0.0 -0.2 0.3 -0.5 -0.3 1.2 -0.2 -0.0 -0.5 0.0 -0.8 -0.6 -0.4 -0.8 -0.5 -0.4 -0.4 -0.4 -0.3 -0.5 -0.6 -0.5 -0.2 -0.6 -0.5 0.2 -1.1 -0.7 -0.7 -0.7 -0.4 -0.3 -1.4 -1.8 -0.4 -0.2 -0.5 -1.7 -0.5 -0.2 -1.8 -0.3 -0.4 -0.3 -0.4 -0.6 -1.0 -0.9
Frequency of tiredness / lethargy in last 2 weeks 0.1 0.2 1.4 0.2 0.3 0.4 0.6 0.7 0.7 0.4 -0.0 0.4 0.0 0.5 0.3 0.5 -0.2 0.7 0.3 0.4 0.4 0.3 0.4 0.5 -0.2 -0.2 0.3 0.4 0.6 0.8 -0.4 0.3 -0.0 0.0 0.5 0.2 0.8 0.1 -0.1 0.1 -1.2 0.6 0.8 0.1 0.5 0.2 1.0 0.2 -0.0 -0.3 0.2
Falls in the last year 1.7 2.3 5.0 1.9 1.6 1.4 1.4 1.6 0.9 1.8 1.5 1.8 0.0 0.4 2.0 1.8 1.8 1.3 1.5 1.8 1.4 1.6 1.4 1.5 1.9 1.0 1.2 1.3 1.4 1.2 2.2 1.8 1.3 1.5 1.8 0.8 1.3 1.6 1.4 1.5 0.4 1.7 1.9 1.1 1.7 1.5 1.6 1.7 1.5 1.2 1.4
Hair/balding pattern: Pattern 3 0.4 0.6 3.2 0.7 0.5 0.8 -0.0 0.2 0.5 0.4 0.6 0.4 0.0 0.8 0.5 0.4 1.1 -0.0 0.7 0.4 0.7 0.4 0.4 0.4 0.6 1.2 1.3 0.4 1.0 -0.1 1.8 0.4 0.9 1.0 0.3 1.1 -0.0 0.9 1.1 1.1 0.9 0.6 0.4 0.9 0.4 0.9 0.3 0.9 1.0 1.0 0.8
Number of live births 0.3 0.4 1.4 -0.5 -1.0 -0.8 -0.4 -0.2 0.2 -0.8 -0.6 -0.6 0.0 -0.4 -0.6 -0.1 -0.9 -0.5 -0.7 -0.6 -0.6 -0.8 -0.5 -0.5 -0.6 -1.0 -1.2 -0.4 -0.9 -0.2 -0.2 -0.1 -0.8 -0.7 -0.5 -0.0 -0.2 -0.8 -0.9 -1.1 -0.3 -0.5 -0.9 -0.1 -0.9 -0.6 -0.7 -0.7 -0.5 -0.9 -0.5
Forced expiratory volume in 1-second (FEV1) 2.3 7.8 17.6 2.8 2.6 2.2 3.3 3.0 2.1 3.3 2.3 3.6 0.0 3.5 2.7 2.5 2.7 3.2 3.3 3.6 2.6 3.5 3.0 3.0 3.4 1.9 2.1 2.8 1.8 3.8 1.9 3.4 2.2 1.8 3.5 1.9 3.9 2.4 2.0 2.2 1.8 3.2 3.4 1.5 4.2 2.4 2.9 2.5 2.7 2.6 2.1
Pulse rate 0.8 1.3 3.1 1.1 1.4 1.8 1.1 1.0 0.8 1.0 0.6 1.1 0.0 1.6 1.5 1.0 1.1 1.2 1.2 1.0 1.3 1.2 1.3 1.7 1.5 1.3 1.6 1.2 1.7 0.8 0.0 1.3 1.0 1.0 1.2 0.8 0.2 1.0 1.0 1.4 0.4 1.0 1.3 0.8 1.2 1.1 1.4 1.1 1.1 1.3 1.0
Happiness 4.5 5.4 13.3 -2.5 -1.4 -1.5 -2.4 -2.6 -1.7 -2.3 -1.7 -2.6 0.0 -2.1 -2.9 -2.7 -2.3 -2.4 -2.5 -2.6 -2.5 -2.2 -2.5 -2.7 -1.9 -1.6 -1.9 -2.5 -1.7 -2.4 -1.9 -2.2 -2.2 -2.6 -2.7 -2.5 -2.2 -2.2 -1.9 -2.5 -2.3 -2.7 -2.3 -3.6 -2.4 -2.5 -1.6 -2.4 -2.1 -2.8 -2.8
Noisy workplace 1.7 2.1 9.7 -1.1 -0.1 -0.1 -2.2 -2.3 -0.9 -1.2 -0.4 -2.0 0.0 -2.6 -1.4 -2.1 -0.8 -2.1 -1.2 -1.8 -1.2 -1.3 -1.8 -2.1 -0.3 -0.1 -0.4 -1.7 -0.3 -2.9 -0.5 -1.5 -0.5 0.3 -1.9 -1.3 -3.1 -0.3 0.3 -0.2 -1.3 -1.8 -1.1 -1.3 -1.8 -0.6 -1.3 -0.7 -0.7 -1.6 -0.8
Qualifications: A levels/AS levels or equivalent 1.2 2.6 9.3 1.3 0.5 1.5 2.0 1.9 1.4 1.5 0.7 1.9 0.0 3.0 1.5 1.6 1.6 2.0 1.4 1.7 1.6 1.4 1.9 2.2 1.1 0.9 1.5 1.9 0.8 2.4 3.1 1.2 1.1 0.4 1.9 1.9 2.5 1.0 0.7 0.7 1.5 1.8 1.4 1.3 2.0 1.3 1.5 1.1 1.4 1.6 1.0
Serious illness, injury or assault of a close relative in last 2 years 1.2 1.4 10.5 1.4 1.3 1.6 1.0 0.7 -0.9 1.3 1.2 1.3 0.0 0.5 1.1 0.4 1.2 0.9 1.3 1.4 1.0 0.9 1.0 1.2 1.1 0.6 1.0 0.8 0.3 1.2 3.2 1.4 1.0 1.0 1.3 0.9 1.5 1.2 1.1 1.0 0.9 1.2 1.2 -0.2 1.6 1.2 1.1 1.4 1.5 0.5 0.6
Mouth/teeth dental problems: Dentures 4.1 6.9 25.2 -2.3 -1.7 -1.9 -3.2 -3.1 -1.6 -2.8 -1.7 -3.4 0.0 -3.5 -2.6 -2.7 -2.0 -3.1 -2.7 -3.3 -2.7 -2.6 -3.0 -3.1 -2.6 -1.1 -1.8 -2.7 -0.2 -4.3 -3.0 -3.0 -2.1 -1.6 -3.3 -3.3 -5.0 -2.0 -1.4 -1.6 -1.8 -3.3 -2.5 -2.1 -3.0 -2.3 -2.7 -2.3 -2.2 -2.6 -2.1
Asthma 0.4 0.8 2.4 -1.1 -1.2 -0.9 -0.5 -0.4 0.4 -1.1 -1.1 -1.0 0.0 -0.5 -0.3 -0.1 -0.7 -0.5 -1.3 -1.1 -0.6 -1.3 -0.6 -0.6 -1.5 -0.8 -0.9 -0.5 -1.4 -0.4 0.1 -1.4 -0.8 -1.1 -0.9 0.1 -0.1 -0.9 -1.0 -1.3 0.2 -0.6 -1.6 -1.0 -1.1 -0.8 -0.6 -1.0 -0.3 -0.5 -1.0
Medication: Ibuprofen (e.g. Nurofen) 0.4 0.5 3.1 1.2 1.8 0.5 -0.8 -0.5 1.4 0.8 1.6 0.3 0.0 0.4 0.5 -0.3 0.3 -0.7 0.8 0.6 -0.2 1.0 -0.4 -0.1 0.3 0.5 0.3 -0.5 1.2 -0.4 1.0 0.7 0.2 0.6 0.3 -1.3 0.3 0.7 0.9 0.3 0.3 0.2 0.9 -0.6 0.9 0.4 -0.1 0.8 0.3 -0.6 -0.3
Medication: Cholesterol lowering 1.2 1.9 4.1 -1.0 -1.5 -1.9 -1.2 -1.1 -0.4 -1.3 -1.0 -1.3 0.0 -1.5 -1.6 -1.3 -2.0 -1.0 -1.3 -1.3 -1.4 -0.9 -1.3 -1.8 -1.6 -1.9 -1.3 -1.3 -0.9 -1.2 -0.4 -1.1 -1.6 -1.4 -1.3 -1.3 -1.2 -1.5 -1.6 -1.4 -1.8 -1.4 -1.4 -1.1 -1.6 -1.5 -1.1 -1.4 -1.6 -1.6 -1.3
Depression (self-reported) 0.4 0.5 2.8 0.5 1.0 -0.1 -1.1 -1.0 1.1 0.1 0.8 -0.4 0.0 -1.5 -0.4 -1.1 -0.5 -1.1 0.1 -0.2 -0.7 0.4 -0.9 -0.9 -0.6 -0.3 -0.3 -1.2 0.1 -0.8 -1.7 -0.0 -0.4 0.1 -0.3 -0.8 0.0 0.1 0.2 -0.0 -0.9 -0.3 0.3 -0.7 -0.4 -0.1 0.3 0.0 -0.2 -1.1 -0.2
Medication: Lansoprazole 0.3 0.3 1.2 -0.5 -1.1 -0.6 1.0 1.0 -0.7 -0.3 -1.1 -0.0 0.0 0.5 0.4 1.1 -0.2 0.8 -0.5 -0.3 0.4 -0.8 0.7 0.2 -0.1 -0.6 -0.7 0.8 0.7 0.5 -0.1 -0.4 -0.3 -0.6 0.1 -0.2 -0.4 -0.5 -0.8 -0.1 -0.1 0.2 -0.3 -0.6 0.5 -0.3 -0.6 -0.6 -0.5 0.4 -0.3
Prospective memory result 1.2 1.5 3.3 -0.9 -1.5 -1.5 -1.7 -1.6 -1.0 -1.3 -0.6 -1.5 0.0 -1.4 -1.4 -1.5 -0.8 -1.8 -1.2 -1.5 -1.2 -1.4 -1.6 -1.7 -1.6 -0.8 -1.1 -1.5 -0.4 -1.6 -1.0 -1.3 -1.0 -0.5 -1.6 -0.8 -0.9 -0.9 -0.7 -0.8 -0.1 -1.2 -1.3 0.1 -1.8 -0.8 -1.3 -1.0 -1.3 -1.4 -0.7
Lung cancer (father) 1.8 2.1 10.1 -0.8 -0.3 -0.5 -2.5 -2.3 -1.0 -1.2 0.0 -1.9 0.0 -2.1 -1.3 -1.9 -0.4 -2.5 -1.1 -1.7 -1.5 -1.1 -2.1 -1.9 -0.9 0.2 -0.3 -1.9 -0.6 -3.2 -0.1 -1.5 -0.8 -0.2 -2.0 -1.4 -3.1 -0.4 0.1 -0.6 -0.2 -1.8 -1.4 -1.0 -1.9 -0.7 -1.1 -0.7 -0.9 -1.3 -0.9
Illnesses of mother 0.3 0.3 2.0 0.4 0.1 0.1 0.9 0.8 -0.3 0.7 0.2 0.6 0.0 -0.1 0.6 0.7 0.2 1.0 0.5 0.6 0.6 0.5 0.6 0.7 0.9 0.1 0.3 0.6 -0.6 0.7 0.2 0.6 0.4 0.4 0.7 0.3 -0.2 0.4 0.1 0.7 -0.5 0.5 0.6 1.4 0.2 0.3 0.8 0.3 0.0 0.8 0.9
Forced expiratory volume in 1-second (FEV1), Best measure 1.8 5.7 13.3 2.2 1.6 1.3 3.3 3.1 1.0 2.8 1.6 3.3 0.0 3.2 2.1 2.5 1.8 3.2 2.6 3.2 2.4 2.9 2.9 2.6 2.8 1.1 1.4 2.7 1.5 3.7 1.6 3.1 1.7 1.2 3.2 1.9 3.5 1.7 1.2 1.6 1.1 2.8 2.7 1.1 3.5 1.8 2.3 1.9 2.3 2.1 1.8
Pulse wave Arterial Stiffness index 0.2 0.2 0.9 -0.3 0.4 0.1 -0.7 -0.8 0.1 -0.6 -0.1 -0.6 0.0 -0.5 -0.4 -0.6 -0.0 -0.8 -0.2 -0.5 -0.3 -0.5 -0.5 -0.8 -0.0 0.4 -0.2 -0.3 0.7 -0.9 0.2 -0.1 0.3 0.3 -0.6 -0.3 -0.9 0.1 0.5 0.2 1.0 -0.5 -0.4 -0.7 -0.3 0.1 -0.6 0.1 0.3 -0.1 -0.4
Impedance of arm (left) 0.1 0.3 2.0 -0.2 -0.1 0.5 -0.1 0.0 -1.2 -0.4 -0.1 -0.3 0.0 -0.5 -0.4 0.1 -0.6 -0.3 -0.2 -0.2 -0.6 -0.5 -0.4 0.4 -0.5 -0.9 -1.1 -0.3 -0.6 -0.4 -0.6 -0.0 -0.6 -0.8 -0.3 -1.4 -0.4 -0.7 -0.6 -0.5 0.3 -0.4 -0.1 -0.5 0.3 -0.7 -0.8 -0.6 -0.5 -0.1 -0.9
Arm fat mass (right) 0.2 0.9 4.1 -0.6 -0.3 -1.7 -1.4 -1.4 1.6 -0.5 0.4 -1.0 0.0 -1.2 -0.8 -1.4 -0.6 -1.2 -0.7 -0.9 -0.9 -0.0 -1.3 -2.0 -1.2 -0.3 -0.4 -1.4 0.6 -0.9 -0.4 -0.8 -0.8 0.0 -1.0 -0.1 -0.2 -0.4 -0.4 -0.4 -1.2 -0.8 -0.8 -0.8 -1.2 -0.5 -0.5 -0.5 -0.6 -1.7 -0.5
Trunk predicted mass 0.1 0.5 2.1 0.6 0.6 -0.2 0.2 0.0 1.4 0.9 1.0 0.6 0.0 0.7 0.2 -0.3 0.7 0.3 0.5 0.6 0.5 1.4 0.3 -0.4 1.0 1.0 1.1 0.1 1.1 0.6 0.6 0.9 0.5 0.8 0.5 1.2 0.9 0.8 0.8 0.7 -0.4 0.6 0.7 0.2 0.3 0.7 1.0 0.7 0.8 0.2 0.8
Standing height 0.2 1.6 5.9 1.8 1.6 1.4 0.8 0.7 1.0 1.8 2.1 1.4 0.0 1.2 0.7 0.2 1.1 0.7 1.4 1.6 0.9 2.4 0.8 1.0 1.9 1.1 1.3 0.5 1.6 0.9 0.0 2.3 0.9 0.8 1.5 0.4 1.2 1.3 1.3 0.9 0.4 1.2 1.7 0.4 1.6 1.2 1.6 1.3 1.4 0.8 0.9
Length of working week for main job 0.1 0.1 1.5 0.2 0.1 0.1 -0.5 -0.4 0.1 -0.0 0.3 -0.3 0.0 -0.5 -0.1 -0.3 -0.1 -0.7 -0.2 -0.3 -0.1 -0.2 -0.3 -0.4 0.3 0.2 0.1 -0.4 0.6 -0.3 1.2 -0.3 0.3 0.4 -0.3 0.2 0.4 0.3 0.5 -0.3 0.7 0.1 -0.2 -0.5 -0.2 0.3 -0.0 0.2 0.4 -0.3 -0.3
Exposure to tobacco smoke at home 0.3 0.3 1.9 0.5 -0.2 -0.7 -0.3 -0.4 1.4 0.1 0.5 0.1 0.0 -0.3 -0.4 -0.7 -0.9 -0.2 0.0 0.1 -0.6 0.6 -0.5 -0.3 -0.8 -0.7 -0.7 -0.7 0.2 -0.4 -0.8 0.2 -0.9 -0.6 0.1 -0.4 -0.7 -0.4 -0.6 -0.6 -1.3 -0.5 -0.4 -0.2 -0.7 -0.6 -0.6 -0.3 -0.3 -0.6 -0.3
Breastfed as a baby 0.8 0.9 4.4 1.1 0.7 1.3 1.3 1.3 -0.2 1.0 0.6 1.3 0.0 1.1 0.4 0.8 0.3 1.3 1.0 1.3 0.9 1.0 1.2 1.6 0.4 -0.2 0.6 0.9 0.1 1.8 -0.7 1.2 0.5 0.1 1.4 0.8 2.1 0.5 0.2 0.6 0.8 1.3 1.1 1.1 1.3 0.7 0.8 0.7 0.5 0.8 0.6
Tense / ‘highly strung’ 0.7 1.2 3.5 -1.3 -1.2 -0.3 -0.6 -0.3 -0.8 -1.2 -1.8 -1.1 0.0 -1.5 -0.6 -0.0 -1.3 -0.6 -1.3 -1.3 -0.6 -1.6 -0.5 -0.6 -1.2 -0.9 -1.2 -0.4 -1.1 -1.1 -0.4 -1.4 -1.0 -1.0 -1.1 -1.3 -1.9 -1.1 -1.1 -0.9 -1.9 -0.9 -1.0 -1.7 -0.8 -1.0 -1.3 -1.3 -1.1 -0.9 -1.2
Seen doctor (GP) for nerves, anxiety, tension or depression 0.3 0.5 3.1 -0.6 0.4 0.2 -0.9 -0.7 1.1 -0.6 -0.6 -0.9 0.0 -1.2 -0.7 -0.7 -0.6 -0.8 -0.7 -0.9 -0.4 -0.8 -0.7 -0.5 -0.7 -0.1 -0.2 -0.8 -0.7 -1.0 -0.8 -1.1 -0.5 -0.3 -0.8 -0.7 -0.7 -0.4 -0.2 -0.0 -1.8 -0.5 -0.0 -1.4 -0.7 -0.3 0.6 -0.6 -0.4 -0.9 -0.6
Hair/balding pattern: Pattern 4 0.1 0.3 4.4 0.1 0.9 0.9 0.4 0.4 0.3 0.3 0.0 0.1 0.0 0.0 0.2 0.4 0.2 0.3 -0.0 0.1 0.4 0.1 0.4 0.2 0.6 0.4 0.6 0.4 2.1 0.6 -0.1 0.5 0.7 0.5 0.2 0.1 0.8 0.4 0.6 0.2 0.1 0.6 0.6 -0.4 0.4 0.5 0.9 0.3 0.6 -0.3 0.0
Birth weight of first child 0.3 0.6 4.5 -0.3 0.7 0.8 0.4 0.6 0.9 0.3 -0.3 0.3 0.0 0.8 0.4 0.7 0.3 0.6 0.5 0.3 0.9 0.5 0.7 0.5 0.8 1.3 1.2 0.9 2.1 0.3 1.0 0.6 1.1 1.2 0.2 0.5 -0.1 0.9 0.8 1.4 0.5 0.5 0.8 1.3 0.2 0.7 0.9 0.7 0.6 0.5 1.3
Peak expiratory flow (PEF) 3.3 7.6 14.4 2.7 2.8 2.2 3.0 2.8 1.7 3.2 2.3 3.3 0.0 3.5 3.0 2.7 3.3 2.9 3.1 3.4 2.6 3.2 2.9 2.9 3.1 2.3 2.4 2.8 1.3 3.4 3.0 3.0 2.4 2.1 3.3 2.6 3.4 2.5 2.3 2.3 1.8 3.1 3.1 1.4 3.8 2.5 2.6 2.6 3.1 2.8 2.2
Pulse wave reflection index 0.8 0.9 2.5 -0.9 -0.9 -1.6 -0.9 -0.7 -0.6 -1.1 -0.7 -1.0 0.0 -0.8 -1.2 -0.7 -1.0 -1.0 -1.0 -0.9 -1.1 -1.2 -1.0 -1.4 -1.3 -1.0 -1.4 -0.8 -0.8 -0.9 0.6 -1.0 -0.9 -0.9 -1.0 -0.8 -0.6 -0.9 -0.9 -1.0 0.1 -1.0 -1.2 -1.1 -0.9 -1.0 -1.3 -0.8 -0.7 -1.0 -1.1
Ever highly irritable/argumentative for 2 days 3.6 4.3 6.6 2.0 2.0 1.9 1.7 1.9 2.0 2.5 1.9 2.2 0.0 1.7 2.0 1.9 2.2 1.7 2.2 2.2 2.3 2.4 1.9 2.0 2.0 2.2 2.4 1.9 2.4 1.5 0.8 1.9 2.2 2.6 2.1 1.6 1.4 2.6 2.4 2.5 1.2 2.4 2.5 2.0 2.1 2.5 2.3 2.4 2.5 2.0 2.3
Loud music exposure frequency 2.0 2.2 4.9 0.8 2.0 1.9 1.5 1.4 0.9 1.3 0.5 1.4 0.0 1.0 1.2 1.2 1.7 1.4 1.3 1.4 1.8 0.9 1.7 1.6 1.5 1.4 1.8 1.6 1.7 1.8 1.6 0.9 1.7 1.7 1.4 1.3 2.2 1.5 1.5 1.7 0.7 1.8 1.8 -0.3 2.2 1.7 1.8 1.5 1.7 1.3 0.9
Qualifications: O levels/GCSEs or equivalent 1.5 2.3 9.2 1.2 0.8 1.9 1.5 1.3 2.3 1.2 0.5 1.5 0.0 3.0 1.9 1.3 1.7 1.5 1.2 1.3 1.3 1.3 1.5 1.9 1.3 1.2 1.4 1.5 1.5 2.2 2.2 1.3 1.2 0.6 1.5 2.1 3.0 1.0 0.9 0.8 1.8 1.7 1.1 1.0 1.6 1.4 1.6 1.0 1.3 1.1 1.0
Mouth/teeth dental problems: Bleeding gums 1.5 2.0 3.6 -0.9 -0.9 -1.6 -1.1 -1.6 -0.4 -1.0 -0.4 -1.1 0.0 -1.6 -1.3 -1.8 -1.6 -1.1 -1.3 -0.9 -1.6 -0.7 -1.5 -1.3 -1.8 -1.7 -1.6 -1.8 -1.8 -1.1 -1.3 -1.2 -1.7 -1.5 -1.1 -1.7 -0.9 -1.4 -1.4 -1.9 -1.8 -1.5 -1.4 -1.8 -1.2 -1.6 -1.6 -1.3 -1.4 -1.9 -1.8
Blood clot in the leg (DVT) 1.0 1.3 4.9 -1.4 -1.1 -0.5 -1.2 -1.1 -0.3 -1.5 -1.3 -1.4 0.0 -1.7 -1.2 -0.9 -1.3 -1.0 -1.2 -1.5 -1.0 -1.1 -1.0 -1.1 -0.2 -0.8 -0.9 -0.9 -1.0 -1.6 -1.0 -1.4 -0.9 -0.7 -1.4 -0.1 -2.2 -1.1 -0.8 -0.4 -1.5 -1.5 -1.3 -0.6 -1.7 -1.1 -0.7 -1.2 -1.0 -1.1 -0.4
Medication: Paracetamol 0.7 1.1 3.7 -0.1 0.4 0.8 1.7 1.7 0.1 0.5 -0.8 0.9 0.0 0.9 1.1 1.9 1.3 1.5 0.6 0.6 1.7 -0.3 1.7 0.9 1.4 1.3 0.7 1.9 0.8 1.2 0.1 0.2 1.6 1.0 0.8 0.9 0.2 0.9 0.9 1.1 1.0 1.2 0.7 0.5 1.1 1.1 0.9 0.7 1.0 1.5 1.1
Headache pain in last month 2.2 3.8 8.2 2.0 1.8 1.4 2.4 2.3 2.2 2.3 1.4 2.6 0.0 2.4 2.4 2.0 1.8 2.4 2.2 2.5 2.0 2.0 2.3 1.9 1.6 0.8 1.4 2.1 1.6 2.3 1.3 2.2 1.5 1.2 2.6 0.6 2.0 1.8 1.4 1.7 0.8 2.2 2.7 1.3 2.9 1.7 2.4 2.0 1.5 2.1 1.6
Medication for cholesterol, blood pressure or diabetes 0.8 1.3 4.2 1.2 1.9 2.0 0.7 0.5 0.8 1.1 1.2 0.9 0.0 1.4 1.1 0.6 1.7 0.4 1.1 1.1 0.7 1.1 0.6 1.3 1.2 1.6 1.3 0.6 0.7 0.7 0.5 1.1 1.3 1.0 1.0 0.1 0.7 1.2 1.5 1.0 1.3 0.9 1.6 0.7 1.6 1.1 1.2 1.2 1.3 1.5 0.6
Glaucoma (self-reported) 3.1 3.6 9.6 1.9 1.9 2.6 1.4 1.2 3.1 1.8 1.8 1.8 0.0 2.5 1.8 1.1 1.9 1.4 1.9 1.8 1.7 2.1 1.6 2.3 2.0 2.2 2.0 1.5 3.1 1.3 1.3 2.0 2.0 1.7 1.8 1.0 0.9 1.9 2.0 2.2 2.3 1.6 2.0 2.5 2.1 1.8 1.5 1.9 1.8 2.2 2.2
Gout (self-reported) 0.4 0.5 2.7 -0.5 -0.1 -0.4 -1.1 -1.0 -1.6 -0.7 -0.3 -1.0 0.0 -1.2 -0.6 -0.8 -0.2 -1.2 -0.7 -0.9 -0.6 -1.0 -0.9 -1.3 -0.3 -0.1 0.0 -0.8 0.1 -1.2 0.5 -0.9 -0.1 0.0 -1.0 -0.9 -0.8 -0.3 0.1 -0.4 0.2 -0.7 -0.6 -0.2 -0.8 -0.3 -0.9 -0.4 -0.4 -0.9 -0.5
Hypothyroidism/myxoedema (self-reported) 0.7 1.4 2.5 -1.1 -1.5 -1.4 -1.2 -1.1 0.7 -1.4 -0.8 -1.3 0.0 -0.8 -1.0 -0.9 -0.9 -1.2 -1.4 -1.4 -1.1 -1.1 -1.1 -1.2 -1.2 -1.2 -1.1 -1.1 -0.7 -1.2 -1.6 -1.4 -1.3 -1.3 -1.3 -0.5 -1.1 -1.4 -1.2 -1.6 -0.8 -1.3 -1.6 -0.7 -1.5 -1.2 -1.5 -1.4 -1.3 -1.4 -1.1
Medication: Amlodipine 0.4 0.6 2.3 -0.5 -1.1 -0.9 -0.9 -0.8 -0.5 -0.6 -0.2 -0.7 0.0 -1.2 -0.6 -0.7 -0.8 -1.0 -0.4 -0.6 -1.0 -0.7 -0.9 -1.1 -0.5 -0.6 -1.2 -0.8 -1.0 -0.8 -0.5 -0.6 -0.8 -0.3 -0.8 -0.1 -0.5 -0.6 -0.6 -0.1 0.2 -0.8 -0.9 0.2 -0.9 -0.7 -1.5 -0.6 -0.7 -0.5 -0.1
Medication: Ventolin 100micrograms inhaler 0.1 0.1 1.0 0.5 -0.1 -0.0 -0.5 -0.3 1.0 0.3 0.7 -0.1 0.0 -0.1 0.3 -0.1 0.1 -0.4 -0.1 -0.0 -0.3 0.5 -0.4 -0.1 -0.4 -0.1 0.0 -0.5 -0.6 -0.5 0.5 0.0 -0.3 -0.1 -0.0 0.1 -0.1 0.0 -0.0 -0.8 0.2 -0.0 -0.5 -0.2 -0.3 -0.0 -0.3 -0.0 0.1 -0.4 -0.3
Birth weight 0.1 0.2 2.2 0.4 0.4 -0.5 -0.2 -0.0 1.3 0.2 0.6 0.2 0.0 0.1 -0.1 -0.1 -0.5 -0.2 0.1 0.3 -0.3 0.5 -0.3 -0.4 0.5 -0.6 -0.7 -0.4 0.3 0.3 0.3 1.0 -0.4 -0.0 0.1 -0.6 1.1 -0.1 -0.2 -0.1 -0.7 0.1 0.7 0.1 -0.1 -0.2 0.6 0.0 -0.3 -1.5 0.0
Chronic bronchitis/emphysema (mother) 0.7 0.8 3.7 -0.2 0.6 0.1 0.1 0.1 -0.1 0.4 0.3 0.0 0.0 -0.3 0.3 0.5 1.1 -0.1 0.5 0.1 0.9 -0.1 0.4 -0.4 0.9 1.9 0.8 0.6 1.6 -0.3 0.3 -0.1 1.7 1.7 -0.1 -0.8 -0.8 1.3 1.6 1.6 1.8 0.5 0.9 0.5 0.6 1.1 -0.1 0.8 1.3 1.3 1.0
High blood pressure (siblings) 0.5 0.7 2.1 -0.7 -0.9 -0.8 -0.6 -0.5 0.3 -0.9 -0.5 -0.7 0.0 -0.9 -0.3 -0.3 -1.0 -0.6 -0.7 -0.7 -0.9 -0.8 -0.8 -0.5 -1.2 -1.4 -1.1 -0.7 -1.4 -0.5 -0.7 -0.4 -1.1 -0.9 -0.7 -0.0 -0.3 -0.9 -1.2 -1.1 -1.0 -0.8 -1.1 -0.6 -1.3 -0.9 -0.6 -0.8 -0.8 -1.2 -0.7
Forced vital capacity (FVC), Best measure 0.8 2.8 8.7 1.3 0.4 0.5 2.8 2.7 0.5 1.8 0.5 2.4 0.0 2.4 1.4 2.1 0.9 2.7 1.6 2.2 1.7 1.8 2.4 2.1 1.9 0.3 0.5 2.2 0.5 3.0 0.9 2.2 0.8 0.1 2.4 1.5 2.4 0.7 0.2 0.8 0.5 2.0 1.6 0.7 2.4 0.9 1.6 0.9 1.3 1.6 1.2
Body fat percentage 0.4 1.7 6.6 -0.9 -0.5 -2.0 -1.9 -1.7 1.0 -1.1 0.1 -1.5 0.0 -1.9 -1.1 -1.6 -1.1 -1.8 -1.0 -1.3 -1.4 -0.5 -1.8 -2.6 -1.8 -0.8 -0.8 -1.8 0.6 -1.7 -1.1 -1.3 -1.2 -0.3 -1.5 -0.9 -1.0 -0.9 -0.6 -0.8 -1.4 -1.3 -1.1 -1.1 -1.6 -0.9 -1.2 -0.9 -1.0 -2.2 -1.0
Leg fat percentage (right) 0.3 1.3 5.9 -0.4 -0.4 -1.9 -1.6 -1.5 1.6 -0.6 0.5 -1.1 0.0 -1.4 -0.8 -1.4 -0.9 -1.4 -0.7 -0.9 -1.3 -0.2 -1.6 -2.4 -1.6 -0.7 -0.8 -1.7 0.3 -1.4 -0.9 -0.9 -1.2 -0.3 -1.0 -1.0 -0.8 -0.6 -0.6 -0.7 -1.4 -1.1 -0.8 -0.9 -1.3 -0.8 -0.8 -0.6 -1.0 -1.9 -0.8
Arm fat-free mass (right) 0.1 0.6 2.8 0.5 0.7 -0.3 0.3 0.2 1.7 0.9 0.9 0.6 0.0 0.6 0.4 0.0 0.8 0.5 0.6 0.6 0.5 1.4 0.4 -0.4 0.8 1.0 1.1 0.3 1.3 0.8 0.1 0.8 0.6 0.8 0.5 1.3 1.0 0.8 0.7 0.6 -0.7 0.7 0.7 0.1 0.3 0.7 1.2 0.6 0.7 0.0 0.7
Exposure to tobacco smoke outside home 1.9 2.5 5.9 1.0 0.8 0.7 2.4 2.2 0.6 1.2 0.0 1.9 0.0 1.8 2.1 2.2 1.5 2.4 1.4 1.7 2.1 0.9 2.3 1.9 1.1 0.8 0.7 2.1 1.0 2.3 1.6 1.2 1.3 1.4 1.9 2.3 1.8 1.2 0.7 1.6 0.5 1.9 1.3 1.4 1.7 1.6 1.2 1.4 1.5 1.9 1.6
Comparative body size at age 10 0.6 1.6 3.2 -1.0 -0.7 -1.8 -1.5 -1.5 1.0 -1.0 -0.2 -1.4 0.0 -0.9 -1.5 -1.6 -1.1 -1.6 -1.1 -1.3 -1.5 -0.7 -1.6 -1.7 -1.4 -1.3 -1.1 -1.8 -0.9 -1.0 -0.7 -1.3 -1.5 -1.0 -1.4 -1.3 -0.3 -1.2 -1.3 -1.3 -1.3 -1.3 -0.9 -0.9 -1.0 -1.3 -1.0 -1.2 -1.5 -1.8 -1.5
Number of full brothers 0.5 0.6 2.8 -0.7 -0.2 0.1 -1.0 -0.9 -1.0 -0.7 -0.4 -1.1 0.0 -1.5 -0.9 -0.7 -0.3 -1.0 -0.8 -1.0 -0.6 -0.7 -1.0 -1.0 -0.4 -0.2 0.1 -0.8 -1.0 -1.1 0.1 -1.0 -0.2 -0.0 -1.1 -0.6 -1.4 -0.1 -0.0 -0.8 -0.3 -0.8 -1.0 -1.7 -0.9 -0.4 -0.5 -0.4 -0.4 -0.9 -1.0
Worry too long after embarrassment 0.2 0.3 2.7 -0.0 -0.1 -0.2 -0.0 0.4 0.7 -0.1 -0.2 -0.2 0.0 0.3 -0.2 0.5 -0.7 -0.1 -0.2 -0.1 -0.5 -0.1 -0.3 -0.6 -0.5 -0.5 -0.5 -0.1 -0.5 -0.3 -0.7 -0.2 -0.7 -0.5 -0.1 -1.6 -0.6 -0.5 -0.6 -0.3 -1.4 -0.2 0.4 -0.9 0.4 -0.5 -0.3 -0.3 -0.6 -0.2 -0.7
Seen a psychiatrist for nerves, anxiety, tension or depression 0.2 0.3 2.2 -0.8 -0.3 -0.5 0.1 0.2 -0.5 -0.5 -1.1 -0.3 0.0 -1.5 0.3 0.4 -0.9 0.2 -0.7 -0.5 0.1 -1.0 0.2 -0.5 -0.6 -0.3 -0.3 0.2 -0.5 -0.1 0.2 -0.8 0.1 0.0 -0.3 -0.3 -0.6 -0.3 -0.3 0.2 -1.1 -0.2 -0.1 0.3 -0.6 -0.2 0.2 -0.3 -0.2 -0.1 0.3
Wheeze or whistling in the chest in last year 1.2 2.1 8.5 -2.1 -1.4 -1.5 -1.5 -1.4 -0.8 -1.7 -1.5 -2.0 0.0 -2.5 -1.2 -0.9 -0.6 -1.7 -1.7 -2.0 -1.0 -2.1 -1.4 -2.3 -0.9 -0.3 -1.0 -1.1 -1.3 -2.3 0.0 -2.5 -0.7 -0.4 -2.1 -1.2 -2.9 -0.8 -0.6 -0.1 -0.6 -1.6 -1.5 -1.2 -1.8 -1.0 -1.3 -1.1 -0.9 -0.4 -0.7
Number of children fathered 0.5 0.5 2.6 1.1 0.8 0.9 0.7 0.6 1.3 0.8 1.0 0.9 0.0 1.6 0.6 0.4 0.5 0.8 0.8 0.9 0.4 1.1 0.6 0.6 0.3 0.3 0.4 0.4 0.0 0.6 1.0 0.9 -0.0 0.1 1.0 0.0 0.3 0.3 0.2 0.6 -0.2 0.5 1.1 -0.0 1.3 0.4 0.8 0.6 0.5 0.7 0.3
Reason for reducing amount of alcohol drunk: Health precaution 0.7 0.8 2.4 -1.1 -0.7 -0.8 -0.8 -0.4 -0.4 -1.3 -1.6 -1.1 0.0 -0.7 -0.9 -0.2 -1.4 -0.8 -1.0 -1.1 -0.8 -1.4 -0.8 -1.2 -1.3 -0.6 -1.0 -0.5 -0.0 -0.6 -0.0 -1.3 -0.6 -0.6 -1.1 -1.1 -0.3 -0.9 -0.8 -0.6 -0.3 -0.7 -0.9 -0.9 -0.8 -0.7 -1.3 -1.1 -0.8 -1.1 -0.9
Age at first live birth 0.2 0.3 2.7 0.1 0.3 1.0 0.4 0.1 -0.2 0.3 -0.0 0.4 0.0 0.3 0.6 0.2 0.4 0.4 0.6 0.3 0.6 -0.1 0.6 0.7 1.3 0.7 0.5 0.5 0.6 0.2 0.9 0.6 1.0 0.4 0.3 0.1 0.0 0.6 0.6 0.3 1.6 0.3 0.0 0.9 0.2 0.6 0.4 0.6 0.5 0.9 0.6
Pulse wave peak to peak time 0.3 0.3 1.2 0.6 -0.1 0.1 0.9 0.9 0.0 0.8 0.4 0.8 0.0 0.7 0.6 0.7 0.3 0.9 0.5 0.7 0.5 0.8 0.6 0.8 0.4 -0.1 0.5 0.5 -0.2 1.1 -0.1 0.4 0.0 -0.0 0.8 0.4 1.0 0.2 -0.1 0.0 -0.7 0.8 0.6 0.8 0.5 0.2 0.8 0.2 0.0 0.3 0.6
Health satisfaction 1.8 2.3 6.8 -0.7 -0.2 -1.4 -1.9 -1.8 0.9 -1.0 0.2 -1.4 0.0 -1.0 -1.6 -1.9 -1.4 -1.8 -0.9 -1.2 -2.1 -0.7 -2.1 -2.3 -1.1 -1.2 -1.1 -2.1 -0.2 -2.0 -2.0 -0.3 -1.8 -1.4 -1.4 -2.0 -1.4 -1.4 -1.2 -1.6 -2.6 -1.8 -0.8 -1.3 -1.8 -1.6 -0.6 -1.3 -1.7 -2.6 -1.5
Shortness of breath walking on level ground 2.0 2.4 5.8 -1.2 -1.6 -2.4 -1.1 -1.0 -0.8 -1.6 -1.4 -1.3 0.0 -1.5 -1.6 -1.1 -2.0 -1.0 -1.4 -1.4 -1.5 -1.3 -1.3 -1.6 -2.1 -1.8 -1.4 -1.2 -0.9 -1.4 -2.3 -1.3 -1.9 -1.8 -1.3 -1.4 -1.9 -1.7 -1.9 -1.8 -1.9 -1.7 -1.6 -1.4 -1.6 -1.8 -1.5 -1.8 -1.5 -1.7 -1.4
Qualifications: College or University degree 0.3 0.8 6.5 0.3 0.2 1.7 0.6 0.3 1.2 0.7 0.2 0.5 0.0 1.1 1.0 0.5 1.1 0.5 0.3 0.5 0.8 0.5 0.7 1.3 1.1 0.8 1.1 0.8 1.1 1.0 1.3 0.3 1.1 0.5 0.5 1.0 1.7 0.9 0.9 0.3 2.6 1.0 0.2 0.3 0.9 1.1 0.5 0.8 1.0 0.9 0.2
Eye problems/disorders: None of the above 1.3 1.5 3.4 -0.6 -1.0 -1.7 -1.4 -1.3 -0.3 -1.0 -0.3 -1.1 0.0 -1.3 -1.6 -1.5 -1.7 -1.5 -1.2 -1.0 -1.3 -0.6 -1.3 -1.5 -1.2 -1.3 -1.4 -1.5 -1.5 -1.2 -0.8 -0.7 -1.4 -1.4 -1.1 -1.3 -0.5 -1.2 -1.1 -1.9 -0.7 -1.1 -1.3 -1.6 -1.4 -1.1 -1.0 -1.0 -1.3 -1.8 -1.5
Mouth/teeth dental problems: Loose teeth 0.7 0.8 2.6 0.6 1.3 0.6 0.3 0.1 0.4 1.0 1.0 0.6 0.0 0.2 0.8 0.2 0.9 0.3 0.9 0.6 1.0 0.5 0.6 0.3 0.7 1.6 0.9 0.5 0.9 -0.0 -1.2 0.5 1.4 1.6 0.5 -0.6 -0.5 1.4 1.5 1.1 0.8 0.6 1.3 0.9 0.8 1.2 0.8 1.1 0.9 1.1 0.9
Emphysema/chronic bronchitis 1.3 1.5 4.7 -1.5 -0.5 -0.2 -1.9 -1.7 -0.6 -1.4 -0.9 -2.0 0.0 -1.9 -0.8 -1.0 -0.4 -2.1 -1.4 -1.8 -1.0 -1.7 -1.6 -1.8 -0.2 0.2 -0.1 -1.3 -0.1 -2.2 -0.6 -1.5 -0.3 0.2 -2.0 -0.8 -1.8 -0.5 -0.0 -0.3 0.3 -1.3 -1.3 -0.7 -2.0 -0.5 -1.1 -0.7 -0.8 -1.1 -0.7
Medication for pain relief, constipation, heartburn 0.0 0.1 0.7 0.2 -0.2 0.4 0.2 0.0 -0.8 0.1 0.2 0.2 0.0 0.1 -0.0 -0.1 0.1 0.1 -0.0 0.2 -0.0 0.0 0.0 0.6 -0.1 -0.2 0.1 -0.1 -0.6 0.5 0.5 0.3 -0.2 -0.2 0.2 0.6 0.8 -0.1 -0.2 -0.1 0.4 0.2 -0.0 0.2 0.1 0.1 0.3 0.0 0.1 0.3 0.0
Neck or shoulder pain in last month 4.8 6.8 12.2 3.1 2.8 2.9 2.4 2.5 2.9 3.1 2.8 3.0 0.0 2.7 3.2 2.5 3.1 2.4 3.3 3.1 2.5 2.9 2.4 2.8 3.0 1.9 2.1 2.2 2.4 2.5 1.2 2.8 2.3 2.3 3.0 1.1 2.6 2.5 2.4 2.4 1.8 2.9 3.3 2.0 3.5 2.7 2.9 2.7 2.2 2.3 2.2
Medication: Blood pressure 0.7 1.1 4.8 -0.9 -2.0 -2.2 -0.5 -0.3 -1.0 -0.9 -1.0 -0.7 0.0 -1.0 -0.8 -0.3 -1.5 -0.3 -0.9 -0.8 -0.8 -0.9 -0.6 -1.2 -1.1 -1.6 -1.3 -0.5 -1.3 -0.4 -1.1 -0.9 -1.3 -1.1 -0.8 0.0 -0.4 -1.2 -1.5 -1.3 -0.7 -0.8 -1.6 -0.4 -1.4 -1.1 -1.3 -1.2 -1.2 -1.4 -0.6
Angina (self-reported) 1.5 2.0 4.7 -1.3 -1.1 -1.6 -1.8 -2.0 -1.5 -1.3 -0.7 -1.7 0.0 -1.9 -1.8 -2.1 -1.1 -1.7 -1.1 -1.6 -1.4 -1.2 -1.7 -2.1 -1.2 -0.6 -1.0 -1.7 -0.8 -2.0 -1.3 -1.7 -1.0 -0.5 -1.8 -1.9 -2.2 -0.8 -0.6 -0.6 -0.4 -1.7 -1.3 -1.4 -1.2 -1.1 -2.1 -1.1 -1.2 -1.2 -1.1
Migraine (self-reported) 0.2 0.2 1.1 0.2 -0.3 0.7 0.8 0.9 1.1 0.3 -0.1 0.4 0.0 0.9 0.6 0.9 0.3 0.7 0.2 0.4 0.4 0.1 0.6 0.6 0.6 0.1 0.1 0.7 -0.3 0.5 0.8 0.0 0.0 -0.2 0.5 -0.0 -0.1 0.0 -0.0 0.7 0.0 0.4 0.5 -0.1 0.8 0.1 -0.1 -0.0 -0.1 0.4 0.4
Medication: Ibuprofen 0.4 0.5 3.2 1.1 1.8 0.4 -0.9 -0.6 1.7 0.6 1.6 0.2 0.0 0.4 0.4 -0.4 0.2 -0.7 0.8 0.5 -0.4 0.9 -0.6 -0.2 -0.1 0.5 0.1 -0.6 1.1 -0.4 0.0 0.5 0.1 0.5 0.2 -1.5 0.2 0.5 0.8 0.1 0.2 0.1 0.8 -0.6 0.8 0.3 -0.2 0.6 0.1 -0.7 -0.4
Medication: Allopurinol 0.5 0.7 2.4 -0.0 0.2 -0.3 -1.4 -1.3 -1.0 -0.4 0.3 -0.8 0.0 -1.0 -1.0 -1.5 -0.7 -1.4 -0.6 -0.6 -1.1 -0.3 -1.3 -1.3 -0.4 -0.5 -0.2 -1.4 -0.0 -1.1 -0.4 -0.2 -0.5 -0.4 -0.8 -1.6 -0.3 -0.4 -0.2 -1.3 -0.2 -0.8 -0.6 -0.4 -0.8 -0.5 -0.7 -0.5 -0.6 -1.3 -1.1
Medication: Omeprazole 0.2 0.2 2.9 0.1 -0.1 0.3 -0.2 -0.2 1.7 0.3 0.5 -0.0 0.0 0.4 0.3 -0.1 0.3 -0.1 0.2 0.1 -0.1 0.5 -0.1 -0.5 0.7 0.6 0.5 -0.0 0.9 -0.6 -1.1 0.3 0.1 0.3 0.0 -0.2 -1.1 0.2 0.4 0.6 -0.1 -0.2 0.2 0.2 0.2 0.0 -0.4 0.2 0.4 0.3 0.4
Medication: Seretide 50 evohaler 1.2 1.3 5.0 0.3 1.0 1.6 0.5 0.9 2.2 0.6 0.3 0.5 0.0 0.9 1.5 1.6 1.2 0.4 0.6 0.4 1.4 0.4 1.0 0.6 1.4 2.1 1.5 1.3 1.5 -0.0 1.0 0.5 1.6 1.5 0.4 1.1 -0.2 1.3 1.7 1.5 1.0 1.0 1.0 0.3 0.3 1.5 1.4 1.3 1.8 1.3 1.2
Mean time to correctly identify matches 1.0 1.9 5.1 -0.7 -0.9 -1.1 -1.8 -1.6 -0.1 -1.1 -0.3 -1.5 0.0 -1.6 -1.0 -1.4 -1.0 -1.8 -1.4 -1.4 -1.4 -1.4 -1.8 -1.6 -2.0 -0.8 -1.0 -1.8 -0.9 -2.0 -1.6 -1.4 -1.2 -0.7 -1.5 -1.5 -1.7 -0.9 -0.7 -1.6 -1.1 -1.4 -1.4 -0.6 -2.2 -1.0 -1.3 -1.0 -1.4 -2.2 -1.1
Heart disease (mother) 0.6 0.8 2.8 -0.2 -0.0 -0.8 -1.6 -1.6 0.5 -0.8 0.3 -1.0 0.0 -0.5 -1.0 -1.5 -0.5 -1.7 -0.6 -0.8 -1.0 -0.2 -1.2 -1.4 -0.8 -0.2 0.0 -1.3 0.3 -1.5 -0.1 -0.6 -0.7 -0.5 -1.0 -0.8 -0.5 -0.5 -0.1 -0.8 0.6 -0.9 -0.9 -1.2 -0.8 -0.5 -1.0 -0.4 -0.4 -1.1 -1.1
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.7 0.8 4.7 -0.2 -1.2 -1.5 0.6 0.6 0.9 -0.0 -0.1 0.4 0.0 0.2 -0.4 0.3 -1.1 0.6 -0.1 0.4 -0.6 0.1 -0.0 0.2 -1.2 -1.7 -1.6 0.0 -2.2 0.7 -1.9 -0.1 -1.3 -1.3 0.3 -0.7 0.5 -1.0 -1.5 -1.3 -0.6 -0.2 -0.6 0.1 0.0 -1.1 -0.9 -0.8 -1.0 -0.4 -0.5
Whole body fat mass 0.3 1.1 4.9 -0.6 -0.3 -1.8 -1.6 -1.5 1.4 -0.7 0.4 -1.2 0.0 -1.5 -1.0 -1.5 -0.8 -1.4 -0.8 -1.0 -1.1 -0.0 -1.5 -2.2 -1.4 -0.5 -0.5 -1.6 0.8 -1.3 -0.7 -0.8 -1.0 -0.0 -1.1 -0.4 -0.6 -0.6 -0.4 -0.5 -1.5 -1.0 -0.9 -1.0 -1.4 -0.6 -0.7 -0.6 -0.7 -2.0 -0.7
Leg fat mass (right) 0.2 0.7 4.1 -0.3 -0.1 -1.5 -1.2 -1.1 1.9 -0.3 0.5 -0.8 0.0 -1.0 -0.7 -1.2 -0.5 -1.0 -0.5 -0.6 -0.9 0.2 -1.2 -2.0 -1.0 -0.3 -0.3 -1.2 0.9 -0.8 -0.4 -0.6 -0.7 0.1 -0.8 -0.4 -0.2 -0.3 -0.3 -0.4 -1.4 -0.7 -0.5 -0.8 -1.0 -0.4 -0.3 -0.3 -0.6 -1.6 -0.5
Arm predicted mass (right) 0.1 0.5 2.0 0.5 0.8 -0.3 0.0 -0.1 1.4 0.8 1.0 0.4 0.0 0.4 0.3 -0.2 0.8 0.2 0.5 0.5 0.4 1.4 0.2 -0.6 0.9 1.1 1.1 0.1 1.4 0.5 0.1 0.7 0.6 1.0 0.4 1.1 0.8 0.8 0.9 0.7 -0.4 0.6 0.7 0.1 0.3 0.7 1.1 0.7 0.8 0.0 0.7
Pulse rate, automated reading 0.6 2.1 4.1 0.9 1.1 0.8 1.7 1.8 -0.2 1.3 0.4 1.4 0.0 1.6 1.8 1.9 1.5 1.8 1.3 1.3 1.8 1.1 1.9 1.2 1.2 1.8 1.8 2.0 1.5 1.3 1.1 1.0 1.5 1.4 1.5 1.5 0.6 1.3 1.2 1.9 0.4 1.5 1.5 1.6 1.2 1.5 1.9 1.4 1.4 2.0 1.7
Alcohol intake frequency. 0.2 0.5 2.6 -0.5 0.7 1.4 -0.8 -1.0 -1.6 -0.5 -0.3 -0.7 0.0 -1.0 -0.5 -0.9 0.3 -0.9 -0.5 -0.7 -0.3 -0.5 -0.6 0.3 0.3 0.6 1.0 -0.6 -0.1 -1.3 -0.4 -0.7 -0.1 0.2 -0.8 0.1 -1.6 -0.0 0.4 0.8 -1.3 -0.7 -0.2 -1.2 -0.7 -0.2 0.4 -0.2 0.1 0.0 -0.1
Comparative height size at age 10 0.4 2.3 5.8 1.9 1.3 1.1 0.6 0.3 1.4 2.0 2.3 1.3 0.0 1.1 1.0 -0.0 1.8 0.7 1.5 1.5 1.3 2.4 0.9 0.9 2.4 1.8 2.3 0.7 2.4 0.8 1.4 1.9 1.5 1.7 1.5 1.5 1.0 1.9 2.0 1.4 1.8 1.4 1.4 1.2 1.6 1.8 0.9 1.9 2.0 1.2 1.6
Number of full sisters 0.9 1.1 3.0 1.0 0.7 1.0 1.0 0.9 0.4 0.9 0.3 1.0 0.0 0.4 0.9 0.9 0.7 1.0 1.1 1.0 1.2 0.5 1.1 0.8 1.1 0.8 1.2 1.1 1.5 0.9 0.4 1.0 1.2 1.1 1.1 0.4 0.7 1.2 1.1 1.7 1.3 1.1 1.4 1.7 1.0 1.2 1.0 1.1 0.9 1.4 1.4
Suffer from ‘nerves’ 0.2 0.2 2.6 0.5 0.6 -0.4 -0.3 0.2 -0.3 0.2 0.3 0.0 0.0 -1.4 0.1 0.5 -0.6 -0.4 0.3 0.1 0.0 0.3 -0.2 -0.8 0.2 0.0 -0.3 -0.1 0.4 -0.7 -1.0 0.4 0.2 0.7 0.0 -1.6 -0.6 0.3 0.4 0.2 -0.4 0.2 0.5 0.4 -0.2 0.3 -0.1 0.2 -0.3 -0.3 0.2
Overall health rating 1.3 2.8 8.1 -0.7 -0.2 -2.0 -2.1 -2.1 0.6 -1.1 0.4 -1.7 0.0 -2.2 -1.7 -2.3 -1.7 -1.9 -1.1 -1.4 -2.0 -0.8 -2.2 -2.6 -1.6 -1.4 -1.3 -2.3 0.3 -2.3 -2.2 -0.9 -1.8 -1.0 -1.6 -2.8 -2.0 -1.3 -1.1 -1.3 -2.0 -1.9 -0.9 -1.5 -1.6 -1.6 -1.3 -1.3 -2.0 -2.7 -1.5
Chest pain or discomfort 1.1 1.6 3.6 -1.2 -0.7 -1.2 -1.2 -1.7 -1.1 -1.3 -1.1 -1.4 0.0 -1.7 -1.2 -1.8 -0.8 -1.2 -1.1 -1.3 -1.1 -1.3 -1.1 -1.7 -1.8 -0.9 -0.9 -1.3 -1.0 -1.4 -1.8 -1.7 -1.1 -0.9 -1.4 -1.7 -1.4 -1.1 -1.0 -0.8 -0.9 -1.5 -0.9 -1.9 -0.7 -1.1 -1.1 -1.0 -1.1 -0.7 -1.5
Had major operations 0.7 0.8 2.7 -0.8 -0.6 -1.1 -1.2 -1.2 0.5 -0.8 -0.3 -1.2 0.0 -0.4 -1.1 -1.3 -0.9 -1.1 -0.8 -1.1 -1.0 -0.2 -1.1 -1.6 -0.9 -0.6 -0.8 -1.1 0.3 -0.9 -1.6 -0.3 -0.7 -0.3 -1.1 -0.4 -0.5 -0.6 -0.6 -0.7 -0.4 -0.9 -1.1 -0.6 -1.1 -0.7 -1.0 -0.6 -1.1 -1.3 -0.8
Age at last live birth 0.4 0.5 3.2 0.2 0.5 1.4 0.1 0.2 0.8 0.4 0.3 0.4 0.0 1.0 0.5 0.5 0.7 0.1 0.7 0.4 0.5 0.3 0.4 0.9 1.0 1.2 0.9 0.5 1.0 0.2 1.3 0.7 1.0 0.8 0.2 0.8 0.6 0.8 0.9 0.6 1.8 0.5 0.1 1.0 0.0 0.8 0.3 0.7 0.8 0.6 0.8
Family relationship satisfaction 1.2 1.5 4.0 -2.0 -1.2 -1.1 -0.9 -0.9 -1.6 -1.8 -2.0 -1.6 0.0 -1.0 -1.5 -0.7 -1.1 -0.9 -1.8 -1.8 -0.9 -1.8 -0.9 -1.3 -1.0 -0.3 -0.9 -0.7 -0.5 -0.8 -0.6 -1.8 -0.7 -1.2 -1.6 -0.2 -1.0 -1.2 -1.0 -0.9 -1.0 -1.2 -1.6 -1.7 -1.8 -1.1 -0.6 -1.4 -0.9 -1.0 -1.0
Leg pain on walking 0.4 0.6 2.2 -0.6 -0.3 -0.5 -1.1 -0.9 -0.6 -0.9 -0.6 -0.9 0.0 -1.5 -0.9 -0.8 -0.9 -1.1 -0.7 -1.0 -0.4 -0.7 -0.7 -1.2 -0.4 0.1 0.4 -0.7 0.5 -1.4 -0.2 -1.1 -0.2 -0.0 -1.0 -0.5 -1.3 -0.4 0.0 -0.1 -0.7 -0.7 -0.5 -0.5 -1.1 -0.3 -0.0 -0.5 -0.7 -0.4 -0.5
Qualifications: NVQ or HND or HNC or equivalent 0.2 0.2 0.9 -0.4 0.5 0.4 -0.5 -0.8 0.2 -0.3 -0.2 -0.4 0.0 -0.3 -0.1 -0.7 0.3 -0.4 -0.1 -0.4 -0.0 -0.4 -0.1 -0.6 -0.2 0.3 0.6 -0.3 1.0 -0.7 -0.1 -0.6 0.3 0.5 -0.4 -0.8 -0.9 0.0 0.4 0.7 -0.3 -0.5 0.3 -0.4 0.2 0.1 -0.3 -0.1 0.1 0.1 -0.2
Commuting to job workplace: Car/motor vehicle 0.2 0.2 1.5 -0.3 -0.4 -1.2 -0.0 0.2 -1.0 -0.4 -0.7 -0.3 0.0 -0.5 -0.4 0.2 -0.3 -0.1 -0.3 -0.3 -0.1 -0.7 -0.0 -0.9 0.0 -0.2 -0.6 0.0 -0.3 -0.4 0.7 -0.3 -0.0 -0.1 -0.3 -0.8 -0.8 -0.3 -0.3 0.3 0.3 -0.2 -0.2 0.2 -0.2 -0.3 -0.8 -0.4 -0.2 0.3 0.1
Illness, injury, bereavement, stress in last 2 years 0.2 0.2 1.1 -0.4 -1.1 -0.6 0.1 0.1 -0.3 -0.5 -0.8 -0.3 0.0 0.3 0.0 0.1 -0.4 0.1 -0.7 -0.5 0.0 -0.5 0.2 0.1 -0.4 -0.1 -0.1 0.1 -0.8 -0.0 -0.3 -0.8 -0.1 -0.5 -0.2 -0.1 -0.5 -0.5 -0.5 -0.5 0.4 -0.3 -0.7 0.5 -0.4 -0.4 -0.8 -0.5 -0.6 0.5 -0.1
Medication: Aspirin 2.7 3.6 8.1 -1.1 -1.9 -2.8 -1.8 -1.7 -1.3 -1.8 -1.1 -1.7 0.0 -2.0 -1.8 -1.8 -2.3 -1.7 -1.8 -1.7 -2.0 -1.1 -1.9 -2.1 -2.0 -2.2 -1.8 -2.0 -1.5 -2.0 -2.4 -1.7 -2.2 -2.0 -1.7 -1.6 -1.9 -2.0 -2.0 -2.3 -2.1 -2.0 -2.1 -1.3 -2.5 -2.0 -1.9 -2.0 -1.9 -2.5 -1.8
Supplements: Vitamin C 1.5 1.8 3.2 1.2 1.2 1.1 1.3 1.2 0.1 1.4 1.1 1.5 0.0 0.9 1.6 1.2 1.3 1.4 1.6 1.4 1.6 1.1 1.5 1.1 1.5 1.3 1.5 1.4 0.9 1.1 0.7 1.4 1.6 1.4 1.5 1.3 0.4 1.5 1.5 1.8 1.0 1.3 1.6 1.6 1.4 1.5 1.6 1.6 1.4 1.8 1.8
Knee pain experienced in last month 3.9 6.1 11.0 2.6 2.9 2.1 2.4 2.4 2.8 2.8 1.9 2.7 0.0 2.2 3.0 2.3 2.7 2.6 2.8 2.7 2.7 2.4 2.6 2.2 2.7 2.6 2.4 2.4 1.5 2.6 1.5 2.3 2.7 2.4 2.9 1.6 2.6 2.6 2.6 2.6 1.2 2.8 3.1 1.0 3.0 2.7 3.3 2.7 2.4 2.3 2.3
Hypertension (Self-reported) 0.6 1.7 9.2 -1.1 -2.4 -3.0 -0.6 -0.3 -1.0 -1.4 -1.4 -1.1 0.0 -0.9 -0.9 -0.3 -1.5 -0.6 -1.4 -1.2 -0.9 -1.5 -0.8 -1.7 -1.8 -1.5 -1.3 -0.6 -1.4 -0.6 -1.0 -1.3 -1.5 -1.3 -1.0 0.4 -0.4 -1.5 -1.7 -1.7 -0.7 -0.9 -2.1 -0.5 -1.8 -1.2 -1.6 -1.3 -1.2 -1.5 -0.8
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.4 0.5 4.1 -0.9 -0.8 -0.5 0.1 -0.0 -1.4 -0.7 -1.5 -0.4 0.0 -0.8 -0.4 0.0 -0.8 0.1 -0.5 -0.6 -0.2 -0.7 0.1 -0.5 -0.3 -0.6 -0.4 0.1 0.4 -0.9 -1.3 -0.6 -0.5 -0.6 -0.5 -1.0 -2.0 -0.6 -0.6 -0.0 -1.2 -0.8 -0.4 -1.1 -0.3 -0.7 -0.5 -0.7 -0.6 0.2 -0.5
Illnesses of father: Heart disease 0.5 0.7 2.5 0.2 0.4 0.5 1.2 1.3 0.6 0.6 -0.3 0.8 0.0 1.5 0.5 1.3 0.3 1.3 0.7 0.7 0.9 0.5 1.1 1.1 0.3 0.3 0.7 1.2 0.6 1.5 1.2 0.6 0.7 0.7 0.8 0.7 1.6 0.6 0.3 0.7 -0.0 1.1 0.9 0.4 0.9 0.7 1.1 0.5 0.6 0.8 0.6
Illnesses of siblings: Diabetes 0.5 0.6 1.7 -0.8 -0.6 -0.6 -0.5 -0.6 0.5 -1.0 -1.0 -1.0 0.0 -0.6 -0.6 -0.6 -0.7 -0.5 -1.2 -1.1 -0.5 -0.7 -0.5 -0.5 -0.6 -0.5 -0.4 -0.4 -1.0 -0.6 -1.3 -1.2 -0.7 -0.8 -0.9 0.2 -1.0 -0.8 -0.7 -1.0 -1.2 -0.8 -1.1 -0.6 -1.2 -0.7 -0.3 -0.9 -0.5 -1.1 -0.6
Smoking status: Previous 2.6 3.8 13.1 -1.7 -1.5 -1.8 -2.3 -2.5 -0.3 -1.7 -0.6 -2.2 0.0 -2.5 -2.4 -2.7 -1.8 -2.2 -2.0 -2.1 -1.8 -1.7 -2.2 -2.6 -1.8 -1.0 -1.5 -2.2 -1.6 -3.1 -0.8 -2.3 -1.6 -1.1 -2.2 -2.5 -3.6 -1.3 -1.0 -1.5 -1.9 -2.4 -1.7 -2.3 -2.1 -1.7 -2.0 -1.4 -1.4 -2.0 -1.7
Forced expiratory volume in 1-second (FEV1), predicted 0.3 0.7 3.3 0.7 1.3 0.9 0.4 0.3 1.7 0.8 0.9 0.7 0.0 0.5 0.5 0.2 0.7 0.3 0.9 0.8 0.3 0.7 0.4 0.1 1.3 0.7 0.2 0.3 1.5 0.6 0.7 1.0 0.7 0.5 0.6 -0.9 0.8 0.7 0.9 1.3 0.3 0.6 1.6 -0.4 1.8 0.6 1.0 0.6 0.6 0.8 0.3
Whole body fat-free mass 0.1 0.5 1.6 0.4 0.6 -0.2 0.2 0.1 1.1 0.8 0.8 0.5 0.0 0.6 0.2 -0.1 0.7 0.4 0.4 0.5 0.5 1.3 0.3 -0.4 0.9 1.0 1.1 0.2 1.2 0.6 0.8 0.7 0.6 0.9 0.4 1.3 0.9 0.8 0.8 0.7 -0.4 0.6 0.6 0.0 0.3 0.7 1.0 0.7 0.9 0.1 0.7
Leg fat-free mass (right) 0.1 0.3 1.6 -0.3 0.4 -0.0 0.1 0.1 0.5 0.4 0.1 0.1 0.0 0.3 -0.0 -0.1 0.5 0.3 -0.1 0.1 0.4 0.6 0.3 -0.3 0.5 0.9 1.0 0.3 1.3 0.5 1.2 0.1 0.6 0.7 0.0 1.3 0.8 0.5 0.5 0.4 -0.5 0.4 0.3 -0.4 0.2 0.5 0.8 0.3 0.6 -0.0 0.3
Arm fat percentage (left) 0.6 2.3 7.0 -1.4 -0.8 -2.1 -2.0 -1.9 1.0 -1.4 -0.3 -1.8 0.0 -2.0 -1.4 -1.7 -1.4 -1.8 -1.5 -1.7 -1.7 -0.9 -2.0 -2.7 -2.1 -1.1 -1.1 -1.9 0.0 -1.6 -0.8 -1.7 -1.5 -0.6 -1.8 -0.9 -0.8 -1.2 -1.1 -1.1 -1.7 -1.5 -1.5 -1.4 -1.9 -1.3 -1.4 -1.3 -1.4 -2.4 -1.4
Average weekly red wine intake 1.1 1.7 9.0 1.1 0.9 1.2 1.7 1.9 -0.3 1.1 0.5 1.6 0.0 2.0 1.4 1.9 1.0 1.7 1.5 1.5 1.1 1.1 1.4 1.8 0.2 0.0 0.4 1.4 0.7 2.3 1.2 1.6 0.6 -0.0 1.6 0.6 3.0 0.5 0.2 0.2 1.0 1.7 1.5 0.7 2.1 0.8 1.4 0.7 0.6 0.9 0.5
Handedness (chirality/laterality): Left-handed 0.2 0.2 1.0 0.4 0.2 -0.5 0.3 0.2 0.5 0.8 0.8 0.7 0.0 0.2 -0.2 -0.3 -0.2 0.5 0.6 0.7 -0.1 1.0 0.1 0.1 0.2 -0.4 -0.3 -0.1 0.1 0.6 0.4 0.9 -0.3 -0.0 0.6 0.0 0.8 0.1 -0.1 -0.3 -0.7 0.2 0.4 0.2 0.5 -0.1 -0.1 0.1 0.3 -0.2 0.3
Mood swings 2.8 5.0 10.5 -2.0 -1.9 -2.5 -1.6 -1.5 -2.1 -1.9 -1.6 -2.0 0.0 -3.2 -2.5 -1.7 -2.9 -1.6 -2.0 -1.9 -2.4 -2.0 -2.1 -2.7 -1.7 -3.0 -3.0 -2.0 -2.8 -1.7 -1.4 -1.8 -2.6 -2.6 -2.0 -3.1 -1.9 -2.5 -2.6 -2.3 -2.5 -2.2 -1.9 -1.9 -2.2 -2.7 -1.8 -2.4 -3.0 -2.4 -2.2
Loneliness, isolation 0.1 0.1 1.3 -0.8 -0.1 0.2 0.0 0.1 -0.5 -0.1 -0.5 -0.2 0.0 -0.8 -0.5 -0.0 -0.2 0.1 -0.3 -0.3 -0.0 -0.2 -0.0 -0.1 0.4 0.0 0.3 0.0 -0.2 0.1 0.5 -0.3 0.0 -0.1 -0.3 0.0 0.0 -0.1 -0.2 -0.1 -1.1 -0.0 -0.1 -1.0 -0.3 -0.3 0.5 -0.3 -0.0 -0.2 -0.1
Long-standing illness, disability or infirmity 1.3 1.9 8.6 -1.2 -0.9 -1.5 -1.7 -1.7 -0.3 -1.3 -0.5 -1.7 0.0 -2.0 -1.0 -1.4 -1.0 -1.8 -1.3 -1.7 -1.1 -1.7 -1.5 -2.0 -1.2 -0.3 -0.9 -1.4 -0.7 -2.5 -1.6 -1.6 -1.0 -0.6 -1.7 -0.9 -2.9 -1.0 -0.4 -0.5 -1.2 -1.7 -1.5 -0.5 -2.2 -1.0 -1.4 -1.2 -0.9 -1.6 -0.3
Ever had bowel cancer screening 0.2 0.3 2.3 0.1 -0.5 -0.3 -0.0 -0.2 0.8 0.1 0.1 0.2 0.0 0.2 0.5 -0.2 -0.2 0.2 -0.1 0.1 -0.2 0.1 0.0 0.0 -0.8 -0.6 -0.6 -0.3 -1.5 0.4 -0.4 0.0 -0.5 -0.5 0.2 0.5 0.7 -0.4 -0.5 -1.2 -1.0 -0.1 -0.5 -0.9 -0.2 -0.3 -0.3 -0.2 -0.3 -1.0 -0.6
Diabetes diagnosed by doctor 1.4 2.3 6.1 -1.2 -1.2 -1.7 -2.2 -2.2 -1.0 -1.4 -0.4 -1.8 0.0 -1.9 -1.9 -2.2 -1.6 -2.0 -1.4 -1.7 -1.6 -0.8 -2.0 -2.1 -1.2 -0.8 -0.2 -2.0 -0.6 -1.7 -1.2 -1.1 -1.2 -0.6 -1.9 -0.2 -0.8 -1.1 -0.9 -1.9 -0.4 -1.6 -2.3 -0.6 -2.5 -1.1 -1.8 -1.3 -0.9 -2.4 -1.2
Ever had stillbirth, spontaneous miscarriage or termination 0.8 0.9 4.2 0.2 0.6 1.3 1.2 1.0 -0.3 0.5 -0.4 0.8 0.0 0.8 0.7 0.9 0.9 1.3 0.7 0.7 1.3 0.3 1.3 1.2 1.0 0.8 0.7 1.4 0.8 1.4 1.4 0.6 0.9 1.0 0.8 2.0 1.0 0.8 0.7 1.1 0.1 1.0 0.6 0.0 1.0 1.0 1.0 0.8 1.2 0.6 1.1
Friendships satisfaction 0.3 0.3 1.6 0.3 0.9 0.6 -0.1 -0.1 0.7 0.4 0.5 0.0 0.0 0.0 -0.1 -0.0 0.5 -0.2 0.3 0.2 0.3 0.5 0.0 -0.5 0.6 1.1 0.8 0.2 1.3 -0.2 1.0 0.0 0.8 0.7 0.1 -0.6 -0.5 0.8 1.0 0.9 0.5 0.2 0.8 -0.2 0.6 0.6 0.8 0.6 0.6 0.5 0.5
Qualifications: nursing, teaching 1.3 2.1 5.8 1.3 1.0 1.5 1.7 1.3 0.0 1.5 0.8 1.9 0.0 1.9 1.3 1.0 1.5 1.8 1.5 1.8 1.4 1.1 1.8 1.9 1.2 1.2 1.2 1.6 0.5 2.1 0.8 1.4 1.4 0.6 1.8 1.5 2.4 1.0 1.0 0.9 1.8 1.6 1.4 1.4 1.8 1.3 1.6 1.2 1.3 1.9 1.2
Commuting to job workplace: Walk 3.1 3.3 9.6 1.9 1.4 2.9 1.4 1.4 0.8 1.7 1.1 1.8 0.0 1.8 2.3 1.6 1.8 1.5 1.8 1.7 1.7 1.7 1.7 2.4 1.1 1.5 2.2 1.7 0.6 2.3 0.9 1.5 1.9 1.8 1.9 3.1 2.8 1.9 1.8 1.2 2.3 2.1 1.3 2.2 1.4 2.1 2.3 2.0 1.8 1.6 2.0
Eye problems/disorders: Cataract 1.3 1.5 3.6 1.4 1.9 1.8 0.9 1.1 0.6 1.2 1.1 1.2 0.0 0.9 1.6 1.3 1.3 1.0 1.3 1.2 1.2 1.1 1.0 1.3 1.2 1.3 1.6 1.1 1.3 0.9 -0.0 1.1 1.2 1.5 1.2 0.6 0.9 1.3 1.4 1.3 0.6 1.3 1.5 0.2 1.8 1.4 1.1 1.5 1.6 1.2 0.8
Mouth/teeth dental problems: Mouth ulcers 0.6 1.0 2.2 0.3 0.8 0.9 1.1 1.1 -1.1 0.8 -0.1 0.8 0.0 0.6 1.1 1.3 1.4 0.9 0.9 0.7 1.3 0.3 1.2 0.8 1.0 1.2 1.0 1.3 0.9 0.9 0.3 0.8 1.5 1.2 0.8 1.3 0.9 1.1 1.2 1.2 0.9 1.2 0.9 0.9 0.9 1.2 1.3 0.9 1.1 1.2 1.2
Medication for cholesterol 0.2 0.4 1.6 0.2 0.8 1.3 0.2 0.0 0.2 0.7 0.5 0.4 0.0 0.6 0.2 -0.2 0.4 0.4 0.5 0.5 0.3 1.0 0.3 0.7 0.9 0.6 0.8 0.3 0.9 0.7 1.3 0.6 0.8 0.6 0.4 0.2 0.9 0.6 0.7 0.1 0.4 0.5 0.7 0.4 0.7 0.5 0.6 0.5 0.6 0.3 0.2
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.1 0.1 1.2 0.4 0.9 0.2 -0.2 -0.0 1.1 0.2 0.6 0.1 0.0 0.4 0.1 0.1 0.2 -0.1 0.3 0.2 -0.3 -0.0 -0.2 -0.3 -0.0 0.4 -0.0 -0.2 -0.0 -0.0 -0.5 0.2 0.1 0.2 0.1 -0.8 0.2 0.1 0.3 0.1 -0.6 0.1 0.8 -0.1 0.6 -0.0 0.1 0.1 0.1 -0.2 -0.4
Back pain experienced in last month 0.2 0.3 0.8 0.5 0.7 0.4 0.1 0.1 -0.3 0.6 0.8 0.4 0.0 -0.1 0.7 0.2 0.9 0.2 0.6 0.5 0.3 0.5 0.3 -0.0 0.8 0.6 0.5 0.2 0.8 0.3 0.8 0.9 0.6 0.5 0.4 0.2 0.6 0.5 0.8 0.4 0.4 0.4 0.7 -0.1 0.7 0.5 0.5 0.5 0.7 0.3 0.3
Mineral and other dietary supplements 0.5 0.7 1.9 -0.8 -0.9 -0.7 -0.8 -1.0 -0.1 -0.5 -0.4 -0.7 0.0 -1.2 -1.3 -1.3 -1.3 -0.8 -0.6 -0.6 -0.9 -0.1 -0.9 -0.6 -0.5 -1.0 -0.9 -1.0 -0.9 -0.9 -1.4 -0.4 -1.0 -0.7 -0.8 -0.6 -0.8 -0.6 -0.9 -0.9 -0.8 -1.0 -1.0 -0.7 -0.9 -0.9 -1.1 -0.7 -0.7 -0.8 -0.8
Breast cancer (self-reported) 0.1 0.1 0.7 0.2 0.0 -0.1 -0.1 -0.4 0.6 -0.0 0.2 0.1 0.0 0.4 0.1 -0.6 0.2 0.0 0.0 0.0 -0.1 0.0 -0.1 0.1 -0.5 -0.2 -0.3 -0.3 0.0 0.1 0.3 0.1 -0.2 -0.5 0.1 0.1 0.3 -0.1 -0.2 -0.1 -0.1 -0.1 -0.0 0.8 -0.4 -0.1 0.5 -0.0 -0.2 -0.6 0.4
Asthma (self-reported) 0.2 0.3 1.3 -0.7 -0.7 -0.4 -0.2 -0.0 0.6 -0.8 -0.8 -0.7 0.0 -0.1 0.1 0.3 -0.3 -0.3 -0.9 -0.8 -0.2 -1.0 -0.3 -0.3 -1.0 -0.4 -0.5 -0.1 -1.0 -0.1 0.6 -1.1 -0.3 -0.7 -0.6 0.5 0.1 -0.5 -0.6 -0.8 0.6 -0.2 -1.1 -0.7 -0.8 -0.3 -0.2 -0.6 0.2 -0.1 -0.6
Osteoporosis (self-reported) 1.5 1.9 5.0 1.0 0.8 1.0 1.8 2.0 0.2 1.2 0.6 1.5 0.0 1.8 1.6 2.1 1.4 1.8 1.3 1.5 1.4 1.0 1.7 1.3 1.6 0.8 1.0 1.8 2.0 1.5 2.2 1.5 1.2 0.7 1.6 0.4 0.9 0.9 0.8 1.2 1.1 1.4 1.6 1.7 1.8 1.1 1.0 1.1 1.1 1.8 1.3
Osteoarthritis (self-reported) 0.6 0.7 2.0 0.9 0.4 0.6 0.8 1.0 1.2 1.1 1.1 1.0 0.0 1.0 1.3 1.2 0.7 0.8 0.8 1.0 0.7 0.9 0.7 0.6 1.2 0.8 0.4 0.7 0.6 1.0 1.2 1.0 0.7 0.7 1.0 0.6 1.4 0.7 0.7 0.7 0.7 1.1 0.8 0.5 0.9 0.7 0.7 0.8 0.7 0.5 0.8
Medication: Aspirin 2.2 2.9 6.4 -1.0 -1.7 -2.5 -1.7 -1.6 -1.4 -1.6 -1.0 -1.6 0.0 -1.8 -1.6 -1.7 -2.1 -1.7 -1.6 -1.6 -1.7 -1.0 -1.7 -2.0 -1.8 -1.8 -1.5 -1.8 -1.2 -1.9 -1.8 -1.5 -1.8 -1.7 -1.6 -1.1 -1.6 -1.7 -1.7 -2.2 -1.7 -1.8 -2.0 -1.0 -2.4 -1.6 -1.8 -1.7 -1.5 -2.3 -1.6
Medication: Gliclazide 0.7 0.8 2.1 -0.8 -0.9 -1.5 -1.1 -1.0 -0.9 -0.9 -0.7 -1.0 0.0 -1.4 -1.2 -1.1 -1.1 -1.0 -0.8 -1.0 -0.9 -0.7 -1.0 -1.4 -0.6 -1.0 -0.5 -1.0 -0.6 -0.9 -0.3 -0.9 -0.9 -0.6 -1.0 -0.8 -0.7 -0.7 -0.8 -1.1 -0.4 -0.9 -1.1 -0.6 -1.0 -0.7 -0.8 -0.8 -0.7 -1.3 -1.0
Illnesses of father: None of the above (group 1) 0.2 0.3 1.5 0.7 0.3 -0.2 -0.6 -0.9 -0.8 0.5 1.2 -0.0 0.0 -1.0 -0.2 -1.1 0.1 -0.7 0.1 0.1 -0.3 0.4 -0.6 -0.4 0.2 0.0 -0.1 -0.9 -0.9 -0.6 -0.8 0.3 0.0 0.1 -0.0 -0.5 -0.3 0.3 0.4 -0.5 0.6 -0.2 -0.1 0.5 -0.3 0.2 -0.3 0.4 -0.1 -0.3 0.0
Smoking status: Current 3.7 5.9 26.2 -1.9 -1.3 -2.0 -2.4 -2.1 -2.1 -2.4 -1.4 -2.5 0.0 -3.5 -2.6 -1.8 -2.4 -2.7 -2.2 -2.5 -2.3 -2.5 -2.5 -2.7 -2.3 -1.9 -2.1 -2.2 -0.9 -3.9 -2.8 -2.7 -2.5 -1.9 -2.6 -4.0 -5.1 -2.1 -1.7 -0.7 -2.7 -2.9 -1.5 -2.6 -2.0 -2.5 -2.2 -2.1 -2.7 -1.3 -2.0
Forced expiratory volume in 1-second (FEV1), predicted percentage 3.5 7.3 13.8 2.8 1.9 1.7 3.5 3.3 2.2 3.3 2.1 3.7 0.0 3.4 2.7 2.8 2.2 3.5 3.1 3.7 2.7 3.3 3.2 3.2 2.8 1.6 1.9 2.9 1.3 3.7 0.8 3.3 1.9 1.7 3.7 2.4 3.3 2.2 1.7 2.2 1.3 3.1 3.1 2.2 3.7 2.2 2.3 2.5 2.8 2.6 2.5
Whole body water mass 0.1 0.5 1.7 0.4 0.6 -0.2 0.2 0.1 1.0 0.8 0.8 0.5 0.0 0.6 0.2 -0.1 0.7 0.4 0.4 0.5 0.5 1.2 0.3 -0.3 0.9 1.0 1.1 0.3 1.2 0.7 0.8 0.7 0.6 0.8 0.4 1.3 0.9 0.7 0.7 0.7 -0.4 0.6 0.6 0.1 0.3 0.7 1.0 0.6 0.8 0.2 0.7
Leg predicted mass (right) 0.1 0.3 2.0 -0.2 0.5 0.0 0.1 0.1 0.6 0.4 0.2 0.1 0.0 0.4 0.0 -0.0 0.6 0.3 -0.0 0.1 0.4 0.7 0.3 -0.3 0.6 1.0 1.1 0.3 1.4 0.6 1.1 0.1 0.6 0.8 0.1 1.3 0.9 0.5 0.6 0.5 -0.5 0.5 0.3 -0.3 0.2 0.5 0.8 0.3 0.7 -0.0 0.4
Arm fat mass (left) 0.2 0.9 4.4 -0.6 -0.1 -1.6 -1.5 -1.4 1.7 -0.5 0.4 -1.1 0.0 -1.3 -0.8 -1.3 -0.6 -1.3 -0.7 -0.9 -1.0 -0.0 -1.4 -2.1 -1.2 -0.3 -0.4 -1.4 0.7 -1.0 -0.6 -0.8 -0.8 0.1 -1.1 -0.3 -0.3 -0.4 -0.3 -0.4 -1.3 -0.8 -0.7 -0.9 -1.2 -0.5 -0.6 -0.5 -0.6 -1.7 -0.6
Number of self-reported non-cancer illnesses 1.4 2.5 5.8 -1.0 -1.3 -2.4 -1.7 -1.5 0.9 -1.3 -0.4 -1.5 0.0 -1.4 -1.1 -1.3 -1.7 -1.6 -1.3 -1.4 -1.7 -1.2 -1.7 -2.4 -2.2 -1.3 -1.9 -1.8 -1.2 -2.0 -1.6 -1.4 -1.8 -1.3 -1.5 -1.9 -2.0 -1.5 -1.4 -1.7 -1.3 -1.7 -1.6 -1.2 -1.6 -1.6 -2.4 -1.5 -1.7 -1.7 -1.5
Average weekly champagne plus white wine intake 1.2 1.6 4.7 0.5 0.2 1.1 1.9 1.8 -0.8 0.7 -0.6 1.2 0.0 1.5 1.6 1.9 1.3 1.8 0.7 0.9 1.8 0.2 1.9 1.6 1.1 0.8 1.0 1.9 0.4 2.0 1.9 0.7 1.3 0.5 1.3 2.2 1.7 0.9 0.7 0.6 1.1 1.6 0.6 0.5 1.1 1.3 1.3 0.9 1.4 1.1 1.0
Miserableness 0.1 0.2 0.9 0.1 -0.4 -0.6 0.1 0.3 0.9 0.3 0.2 0.3 0.0 -0.3 -0.2 0.1 -0.8 0.3 0.1 0.4 -0.1 0.2 0.0 -0.3 -0.2 -0.7 -0.3 -0.1 -0.4 0.5 -0.3 0.2 -0.4 -0.1 0.3 -0.0 0.8 -0.1 -0.5 -0.6 -0.6 0.2 -0.1 0.6 -0.5 -0.1 -0.1 0.1 -0.5 -0.8 0.3
Guilty feelings 0.8 1.2 4.6 0.6 0.6 0.7 2.2 2.1 -0.2 0.9 -0.6 1.5 0.0 0.9 1.4 1.9 0.7 2.1 0.9 1.2 1.4 0.1 1.8 1.3 0.5 0.2 0.4 1.8 0.5 1.6 -0.3 0.9 0.6 0.2 1.5 0.6 0.5 0.6 0.0 1.0 -0.9 1.2 1.2 0.2 1.1 0.7 2.0 0.7 0.5 1.3 1.1
Wears glasses or contact lenses 3.4 3.9 8.8 -1.0 -1.5 -2.5 -2.5 -2.4 0.0 -1.6 -0.2 -1.9 0.0 -1.9 -2.1 -2.5 -2.0 -2.4 -1.7 -1.7 -2.4 -1.0 -2.6 -2.6 -2.2 -1.7 -1.6 -2.7 -1.4 -2.2 -2.4 -1.4 -2.0 -1.5 -1.9 -2.4 -1.4 -1.7 -1.7 -2.8 -1.3 -2.1 -2.2 -0.8 -2.9 -1.8 -2.2 -1.7 -2.3 -3.0 -1.9
Ever taken oral contraceptive pill 2.4 2.6 6.4 1.3 0.9 1.0 1.9 1.9 -0.7 1.2 0.2 1.6 0.0 1.3 2.4 2.2 1.9 1.9 1.3 1.4 2.1 0.6 2.2 1.5 1.8 1.6 1.3 2.2 0.3 1.8 2.1 0.9 2.0 1.5 1.7 1.3 1.0 1.6 1.6 1.7 1.7 1.8 1.6 1.6 1.8 1.9 1.5 1.6 2.0 2.5 1.7
Hearing aid user 0.2 0.2 1.5 -0.8 -1.1 -0.5 0.5 0.4 -0.6 -0.2 -0.9 -0.0 0.0 -0.4 0.1 0.3 -0.5 0.8 -0.3 -0.2 0.2 -0.5 0.4 0.0 -0.3 -0.7 -0.6 0.4 -0.0 -0.1 0.0 -0.2 -0.3 -0.4 -0.0 0.0 -1.2 -0.4 -0.7 0.1 -1.1 -0.3 -0.3 0.4 -0.7 -0.4 -0.2 -0.5 -0.3 -0.1 0.4
Mother’s age at death 0.5 0.6 5.3 -0.1 -0.6 0.0 1.1 1.0 -0.1 0.3 -0.3 0.9 0.0 1.9 0.2 0.7 -0.0 1.3 0.5 0.8 0.0 0.3 0.6 0.7 -0.8 -1.1 -0.3 0.7 -1.0 1.9 -0.9 0.6 -0.5 -0.8 0.8 1.1 2.3 -0.5 -1.0 -0.8 0.1 0.5 0.1 0.4 0.8 -0.3 0.2 -0.2 -0.3 -0.2 -0.1
Financial situation satisfaction 0.6 0.8 4.0 -0.3 0.6 0.1 -1.1 -1.2 0.9 -0.4 0.3 -0.9 0.0 -0.4 -1.0 -1.4 -0.9 -1.0 -0.6 -0.7 -1.1 0.1 -1.2 -0.9 -1.0 -0.5 -0.2 -1.3 -0.1 -0.7 -1.7 -0.5 -0.9 -1.0 -0.8 -0.8 -0.2 -0.7 -0.4 -0.8 -1.4 -0.8 -0.5 -2.0 -0.6 -0.8 0.1 -0.6 -0.7 -1.9 -1.2
Tinnitus: Yes, now most or all of the time 0.2 0.2 1.6 0.4 -0.3 -0.9 -0.7 -0.7 -1.0 0.3 0.6 -0.1 0.0 -0.2 -0.1 -0.7 0.0 -0.5 0.4 -0.0 -0.0 0.5 -0.4 -0.6 0.1 0.1 0.3 -0.6 0.2 -0.5 -1.1 0.0 0.1 0.6 -0.1 0.1 -0.3 0.5 0.4 -0.2 0.4 -0.1 -0.1 1.3 -0.4 0.3 -0.7 0.3 -0.1 -0.0 0.4
Commuting to job workplace: Public transport 0.8 0.9 3.7 -0.7 -1.3 -0.8 -1.3 -1.4 1.0 -1.0 -0.3 -1.1 0.0 -0.3 -0.9 -1.3 -0.7 -1.2 -0.8 -1.0 -1.0 -0.5 -1.2 -0.6 -1.3 -0.7 -0.8 -1.2 -0.7 -0.8 -1.0 -0.8 -0.9 -0.5 -1.1 0.9 -0.0 -0.7 -0.7 -1.2 0.0 -0.9 -1.7 0.2 -1.9 -0.6 -1.0 -0.6 -0.9 -1.9 -0.4
Eye problems/disorders: Glaucoma 1.6 1.9 5.4 1.2 1.1 1.7 1.3 1.0 1.9 1.2 0.9 1.3 0.0 2.1 1.3 0.9 1.3 1.3 1.4 1.3 1.4 1.3 1.4 1.7 1.3 1.7 1.4 1.3 2.3 1.1 1.3 1.4 1.5 1.2 1.4 0.7 0.2 1.2 1.3 1.8 1.5 1.1 1.5 2.0 1.6 1.2 0.9 1.3 1.1 1.8 1.7
Medication: Blood pressure 0.8 1.5 3.6 -0.9 -1.5 -1.9 -1.2 -1.1 -0.3 -1.2 -0.5 -1.2 0.0 -1.4 -1.2 -1.0 -1.3 -1.4 -1.2 -1.3 -1.1 -1.4 -1.2 -1.6 -1.3 -0.9 -1.2 -1.3 -1.1 -1.5 -1.8 -1.0 -1.2 -0.9 -1.2 -0.3 -1.3 -1.1 -1.1 -1.1 -0.5 -1.2 -1.7 -0.2 -1.9 -1.1 -1.7 -1.0 -1.2 -1.3 -0.7
Pain type(s) experienced in last month: Hip pain 0.7 0.9 2.7 1.2 1.0 1.0 1.2 1.2 0.1 1.0 0.8 1.3 0.0 0.7 1.1 1.1 1.0 1.3 1.1 1.2 0.9 0.8 1.2 0.9 1.2 0.2 0.5 1.2 0.6 0.8 1.1 1.1 0.4 0.4 1.3 0.5 0.5 0.5 0.6 1.1 -0.4 0.9 1.5 -0.1 1.6 0.6 1.0 0.7 0.7 1.1 0.8
Supplements: Fish oil (including cod liver oil) 0.5 0.6 1.5 1.1 1.0 0.8 0.5 0.6 0.5 0.7 0.8 0.7 0.0 1.0 1.1 0.7 1.1 0.6 0.7 0.7 0.8 0.5 0.7 0.5 0.2 0.9 1.0 0.6 1.2 0.7 0.8 0.5 0.9 0.9 0.8 0.6 0.7 0.8 0.9 0.8 0.2 0.9 1.0 0.5 0.6 1.0 1.2 0.9 0.8 0.3 0.8
High cholesterol (Self-reported) 0.6 1.1 3.1 1.5 1.3 0.8 1.1 1.2 0.5 1.3 1.2 1.3 0.0 0.6 1.2 1.0 0.6 1.2 1.3 1.3 1.0 1.2 1.0 0.8 0.7 0.4 0.7 0.9 0.8 0.7 1.1 1.3 0.7 0.8 1.4 -0.0 0.2 0.9 0.7 1.5 -0.5 1.0 1.8 1.3 1.2 0.9 1.5 1.1 0.6 1.2 1.3
Medication: Bendroflumethiazide 0.5 0.7 2.2 0.5 -0.2 -0.6 1.1 1.2 -0.1 0.7 0.2 1.0 0.0 1.1 0.8 1.3 0.8 1.0 0.9 0.9 1.0 0.6 1.0 0.5 1.2 0.5 0.2 1.1 0.2 1.1 1.1 0.6 0.6 0.5 0.9 0.8 1.4 0.5 0.3 0.6 1.5 1.1 0.5 1.2 0.8 0.7 0.4 0.7 0.4 1.1 0.9
Medication: Paracetamol 0.5 0.7 3.1 -0.1 0.2 0.3 1.3 1.5 0.1 0.4 -0.5 0.7 0.0 0.7 1.0 1.8 0.9 1.3 0.5 0.5 1.2 -0.3 1.3 0.7 1.1 0.9 0.1 1.6 0.2 1.1 0.0 0.3 1.2 0.7 0.6 0.6 0.4 0.6 0.6 0.7 1.1 0.9 0.5 0.9 0.8 0.7 0.6 0.5 0.6 1.1 1.0
Medication: Lisinopril 0.5 0.6 2.3 -1.5 -1.2 -1.2 -0.2 -0.2 -0.7 -1.1 -1.4 -0.8 0.0 0.1 -0.9 -0.3 -0.9 0.0 -1.0 -1.0 -0.4 -0.9 -0.2 -1.1 -1.4 -0.4 -0.1 -0.1 -0.6 0.1 -0.1 -1.3 -0.4 -0.8 -0.8 -0.4 0.1 -1.0 -1.1 -0.7 0.0 -0.6 -0.8 -0.3 -0.5 -0.7 -0.5 -1.1 -0.7 -0.3 -0.7
Medication: Atorvastatin 3.8 4.7 7.2 -2.1 -1.7 -1.5 -2.0 -2.0 -2.0 -2.3 -1.7 -2.3 0.0 -2.5 -2.6 -2.1 -2.5 -1.9 -2.2 -2.2 -2.5 -2.0 -2.2 -2.3 -2.5 -2.7 -2.2 -2.1 -1.1 -2.1 -1.4 -2.0 -2.5 -2.6 -2.2 -2.3 -1.9 -2.6 -2.4 -2.3 -2.6 -2.5 -1.9 -2.2 -2.0 -2.5 -1.5 -2.3 -2.5 -2.2 -2.5
Illnesses of father: High blood pressure 1.2 1.5 4.8 -0.3 0.2 1.6 2.2 2.1 -0.9 0.4 -1.1 1.1 0.0 1.2 1.2 2.1 1.0 2.1 0.5 0.8 1.5 0.3 1.9 2.0 0.5 0.2 0.6 2.0 0.3 2.1 1.9 0.3 0.8 0.1 1.1 1.8 1.8 0.4 -0.0 0.8 -0.0 1.3 0.7 -0.4 1.4 0.7 1.4 0.2 0.9 1.1 0.4
Alcohol drinker status: Never 0.2 0.3 1.9 -0.3 0.1 0.6 -0.0 0.1 0.7 0.1 0.1 0.0 0.0 1.4 0.3 0.3 0.9 -0.0 0.1 0.0 0.3 0.0 0.2 0.3 0.3 1.3 0.8 0.4 0.9 0.2 0.8 -0.0 0.6 0.5 -0.1 1.4 0.6 0.4 0.7 -0.1 0.7 0.4 -0.3 0.4 -0.3 0.4 0.3 0.2 0.6 -0.1 0.2
Ever smoked 0.8 1.4 5.4 -1.2 -0.2 -0.2 -1.3 -1.3 0.2 -1.3 -0.7 -1.5 0.0 -1.1 -1.2 -1.1 -0.7 -1.4 -1.3 -1.4 -1.1 -1.3 -1.2 -1.4 -1.2 -0.6 -0.6 -1.1 -0.4 -1.8 -0.7 -1.9 -1.1 -0.9 -1.5 -1.8 -1.8 -1.0 -0.6 -0.7 -1.5 -1.3 -0.6 -2.3 -0.8 -1.1 -0.7 -1.0 -0.9 -1.4 -1.5
Basal metabolic rate 0.1 0.5 1.9 0.4 0.7 -0.3 0.0 -0.1 1.4 0.8 1.0 0.4 0.0 0.5 0.2 -0.2 0.7 0.2 0.4 0.5 0.4 1.3 0.2 -0.5 0.7 1.0 1.1 0.1 1.4 0.5 0.8 0.6 0.6 0.9 0.4 1.2 0.9 0.8 0.8 0.7 -0.4 0.6 0.6 -0.0 0.3 0.7 0.9 0.7 0.8 -0.0 0.7
Leg fat percentage (left) 0.2 0.7 3.8 -0.4 -0.1 -1.5 -1.2 -1.1 1.5 -0.4 0.4 -0.8 0.0 -1.1 -0.4 -1.0 -0.4 -1.0 -0.4 -0.7 -0.7 -0.0 -1.1 -2.0 -1.2 -0.1 -0.2 -1.1 0.9 -1.1 -0.8 -0.8 -0.6 0.3 -0.8 -0.5 -0.8 -0.2 -0.1 -0.1 -1.1 -0.7 -0.5 -0.5 -1.0 -0.3 -0.5 -0.2 -0.5 -1.4 -0.3
Arm fat-free mass (left) 0.2 0.8 3.3 0.9 1.0 -0.2 0.1 0.1 1.8 1.2 1.4 0.7 0.0 0.6 0.6 -0.0 1.0 0.3 0.8 0.8 0.5 1.6 0.3 -0.4 1.1 1.2 1.2 0.2 1.2 0.5 0.4 1.1 0.7 1.1 0.7 1.1 0.9 1.1 1.0 0.9 -0.2 0.8 0.9 0.4 0.4 0.9 1.2 1.0 0.9 0.2 1.0
Number of operations (self-reported) 0.2 0.3 1.1 -0.3 -0.7 -1.0 -0.5 -0.3 0.7 -0.2 -0.1 -0.4 0.0 -0.3 -0.4 -0.3 -0.7 -0.3 -0.4 -0.3 -0.5 0.1 -0.5 -0.7 -0.1 -0.7 -0.7 -0.4 0.2 -0.1 -0.9 0.2 -0.5 0.1 -0.4 0.2 0.6 -0.3 -0.5 -0.8 -0.3 -0.1 -0.8 0.4 -1.0 -0.4 -1.0 -0.4 -0.7 -1.0 -0.2
Average weekly beer plus cider intake 0.9 1.3 3.5 -0.1 -0.2 -1.5 -1.4 -1.6 0.1 -0.8 0.5 -0.9 0.0 -1.5 -1.2 -1.8 -0.9 -1.5 -0.6 -0.7 -1.4 -0.4 -1.4 -1.5 -1.3 -0.9 -1.5 -1.7 -1.7 -1.8 -0.7 -0.9 -1.3 -0.8 -0.9 -1.2 -1.9 -0.8 -0.8 -0.5 -1.1 -1.5 -1.1 -0.2 -1.4 -1.2 -1.6 -0.8 -0.9 -1.4 -0.5
Irritability 0.3 0.6 3.1 0.1 0.4 0.2 0.9 1.0 -0.2 0.4 -0.2 0.5 0.0 0.5 0.7 1.0 0.3 0.9 0.3 0.4 1.0 0.2 1.0 0.1 0.0 0.8 0.9 1.0 1.6 0.7 1.8 0.1 1.0 0.8 0.6 0.4 0.3 0.7 0.5 1.0 0.2 0.8 0.9 1.1 0.3 0.8 1.2 0.6 0.5 0.8 1.0
Risk taking 2.2 3.3 7.2 1.8 1.8 1.3 1.9 2.0 1.6 1.7 1.5 2.0 0.0 1.6 1.9 2.0 2.1 1.5 1.9 2.0 1.9 1.3 1.9 1.7 1.8 1.3 1.0 1.7 2.1 2.1 1.2 1.6 1.8 1.9 1.9 1.4 2.7 1.8 1.6 2.1 1.7 2.3 2.3 1.7 2.6 1.9 1.4 1.9 1.7 1.6 1.8
Ever had prostate specific antigen (PSA) test 0.5 0.5 2.9 0.0 -0.7 0.4 0.4 0.4 0.9 0.1 -0.3 0.1 0.0 1.6 0.3 0.4 0.6 0.4 -0.1 -0.0 0.9 -0.1 0.5 0.2 0.4 1.2 1.2 0.6 0.8 0.6 1.7 -0.0 0.9 0.9 0.2 1.7 0.8 0.6 0.7 -0.1 1.7 0.7 -0.5 0.5 0.0 0.9 -0.2 0.6 0.9 0.5 0.4
Fractured/broken bones in last 5 years 0.2 0.2 1.4 0.4 0.3 0.1 0.9 0.8 -0.2 0.3 -0.1 0.6 0.0 0.2 0.4 0.6 0.2 0.8 0.3 0.6 0.2 0.1 0.6 0.6 0.9 -0.5 -0.1 0.6 0.3 1.1 0.3 0.5 -0.1 -0.3 0.7 0.2 1.2 0.0 -0.3 0.2 0.2 0.5 0.5 -0.3 0.9 -0.0 0.2 0.2 -0.1 0.5 0.0
Age started oral contraceptive pill 1.0 1.3 6.4 0.1 1.0 2.0 0.1 0.3 0.7 0.4 0.1 0.2 0.0 1.0 1.3 1.0 1.7 0.2 0.7 0.2 1.2 0.0 0.7 0.8 1.0 2.5 1.9 1.0 1.5 -0.2 1.2 0.2 1.9 1.7 0.1 1.0 -0.6 1.5 1.9 1.1 2.1 0.7 0.5 0.8 0.3 1.5 1.0 1.2 1.6 1.2 1.2
Diastolic blood pressure, automated reading 0.1 0.4 2.5 -0.5 -1.5 -1.6 0.7 0.6 0.7 -0.1 -0.7 0.2 0.0 0.8 0.1 0.5 -0.1 0.9 -0.2 0.1 0.1 -0.4 0.5 -0.1 -0.7 -0.4 -0.4 0.6 -0.2 1.2 0.1 0.1 -0.1 -0.7 0.3 1.2 1.1 -0.5 -0.8 -1.0 0.6 0.2 -0.8 1.2 -0.8 -0.2 -0.1 -0.3 -0.0 -0.5 0.6
Ever depressed for a whole week 1.8 2.2 4.7 -1.5 -1.4 -1.6 -1.7 -1.8 -0.2 -1.4 -0.9 -1.6 0.0 -1.5 -1.8 -1.9 -1.6 -1.5 -1.4 -1.5 -1.7 -1.2 -1.7 -1.5 -1.5 -1.2 -1.2 -1.7 -1.3 -1.6 -1.3 -1.4 -1.5 -1.4 -1.7 -0.6 -1.2 -1.4 -1.4 -1.8 -0.6 -1.7 -2.2 -1.2 -2.0 -1.5 -2.1 -1.5 -1.2 -2.0 -1.4
Unable to work because of sickness or disability 0.3 0.4 3.0 -0.8 -0.7 -0.8 0.3 0.4 -1.4 -0.4 -0.8 -0.2 0.0 -0.9 -0.9 0.1 -1.0 0.4 -0.5 -0.4 -0.3 -0.6 -0.1 0.0 -0.5 -1.1 -0.5 -0.0 -0.5 0.0 0.6 -0.6 -0.9 -1.1 -0.3 -0.2 -0.2 -0.8 -1.1 -0.4 -1.7 -0.3 -0.4 -0.4 -0.6 -0.8 -0.1 -0.9 -0.7 -0.3 -0.2
Commuting to job workplace: Cycle 1.4 1.7 3.4 -1.8 -1.0 -0.3 -1.3 -1.4 0.2 -1.4 -1.2 -1.6 0.0 -1.3 -1.5 -1.4 -1.2 -1.3 -1.6 -1.6 -1.4 -1.4 -1.4 -1.0 -1.4 -0.9 -0.9 -1.3 -1.4 -1.1 -1.1 -1.6 -1.0 -1.4 -1.7 -0.5 -0.8 -1.2 -1.1 -1.5 -1.2 -1.4 -1.5 -1.6 -1.7 -1.3 -0.8 -1.5 -1.0 -1.4 -1.5
Myopia 0.3 0.4 2.1 0.8 0.1 -0.0 -0.2 -0.2 -0.1 0.5 1.0 0.5 0.0 -0.4 0.0 -0.5 -0.6 -0.2 0.3 0.6 -0.7 0.7 -0.4 0.2 -0.3 -1.2 -0.4 -0.8 -0.3 0.4 -0.8 1.0 -0.8 -0.8 0.5 -0.5 1.5 -0.4 -0.7 -1.4 -0.5 0.0 -0.2 -0.4 -0.2 -0.6 -0.5 -0.2 -0.5 -1.4 -0.7
Vascular/heart problems diagnosed by doctor 1.0 2.8 11.6 1.7 3.0 3.4 0.8 0.6 1.4 1.9 2.0 1.4 0.0 1.5 1.3 0.5 2.0 0.7 1.8 1.7 1.1 2.0 1.0 2.2 2.3 1.8 1.6 0.8 1.8 1.1 1.8 1.8 1.8 1.7 1.4 0.2 1.4 1.8 2.1 1.8 0.9 1.4 2.5 0.5 2.3 1.6 1.9 1.6 1.7 1.6 0.9
Cholesterol lowering medication 1.9 2.8 5.0 1.8 1.5 1.3 1.2 1.3 0.5 1.7 1.5 1.6 0.0 1.2 2.2 1.7 2.2 1.2 1.7 1.6 1.8 1.3 1.5 1.2 1.5 2.1 1.9 1.6 2.0 1.0 2.1 1.4 1.9 2.1 1.7 1.6 1.0 2.0 2.0 2.1 1.8 1.8 1.7 1.5 1.6 2.1 1.6 2.0 2.0 1.7 1.9
Medication: Omeprazole (e.g. Zanprol) 0.9 1.1 4.9 0.6 0.2 0.8 0.8 0.8 2.2 1.2 1.1 1.0 0.0 1.5 1.2 0.9 1.2 0.9 1.1 1.1 0.8 1.3 0.9 0.5 1.6 1.4 1.2 1.0 1.2 0.4 0.2 1.1 1.0 1.1 0.9 0.9 -0.1 1.0 1.0 1.2 1.0 0.8 0.9 1.4 1.0 0.8 0.3 1.1 1.3 1.4 1.4
Pain experienced in last month 2.3 3.9 7.5 -2.2 -2.7 -2.7 -1.3 -1.2 -2.6 -2.1 -2.0 -1.8 0.0 -1.3 -2.5 -1.4 -2.5 -1.3 -2.1 -1.9 -1.9 -1.7 -1.6 -1.5 -2.3 -2.3 -1.9 -1.5 -1.9 -1.6 -1.1 -1.9 -2.3 -2.2 -1.9 -1.4 -1.9 -2.2 -2.6 -2.3 -1.1 -2.1 -2.5 -0.6 -2.2 -2.3 -2.6 -2.3 -2.1 -1.4 -1.8
Supplements: Calcium 0.6 0.7 8.3 -0.4 -0.4 0.5 1.0 1.3 -0.4 -0.1 -0.9 0.2 0.0 1.1 1.1 1.7 1.0 0.9 0.1 -0.0 0.8 -0.6 0.9 0.5 1.0 0.9 0.3 1.5 0.7 0.6 2.9 -0.0 0.9 0.3 0.3 0.8 -0.1 0.2 0.4 0.7 0.9 0.7 0.4 0.5 0.6 0.5 0.5 0.2 0.5 1.1 0.6
Basal cell carcinoma (self-reported) 0.1 0.2 1.0 -0.7 -0.2 -0.3 0.1 0.3 -0.9 -0.5 -1.0 -0.3 0.0 -0.2 0.3 0.6 -0.3 0.1 -0.4 -0.4 -0.1 -0.6 0.1 -0.4 -1.0 -0.2 -0.3 0.4 0.3 0.3 -0.6 -0.5 0.1 -0.3 -0.4 -0.4 0.2 -0.3 -0.4 -0.5 -0.0 -0.1 -0.1 0.2 -0.3 -0.3 0.4 -0.5 -0.4 -0.1 -0.2
Heart attack/myocardial infarction (self-reported) 1.1 1.4 8.5 0.2 -0.5 -1.8 -1.6 -1.6 0.9 -0.3 1.1 -0.8 0.0 -1.4 -1.2 -1.8 -0.8 -1.6 -0.1 -0.6 -1.3 -0.1 -1.6 -1.7 -0.8 -0.8 -0.9 -1.7 -0.5 -1.9 -2.9 -0.5 -1.1 -0.4 -0.9 -2.1 -1.9 -0.4 -0.3 -0.8 -0.2 -1.2 -0.6 -0.2 -0.7 -0.9 -1.4 -0.5 -1.1 -1.0 -0.8
Deep venous thrombosis (DVT) (self-reported) 0.8 1.1 4.4 -1.2 -1.1 -0.6 -1.1 -1.0 0.0 -1.3 -1.2 -1.2 0.0 -1.5 -1.1 -0.9 -1.2 -0.9 -1.1 -1.4 -0.8 -1.0 -0.9 -1.0 -0.2 -0.7 -0.9 -0.8 -0.8 -1.5 -1.3 -1.3 -0.8 -0.6 -1.3 -0.1 -2.1 -0.9 -0.7 -0.5 -1.4 -1.3 -1.2 -0.5 -1.7 -1.0 -0.6 -1.0 -0.9 -1.1 -0.4
Heart disease (siblings) 2.0 2.4 6.2 -0.7 -1.4 -1.6 -1.6 -1.6 -0.3 -1.4 -0.7 -1.4 0.0 -1.2 -1.3 -1.6 -1.7 -1.6 -1.5 -1.4 -1.6 -1.1 -1.6 -1.7 -1.7 -1.5 -1.4 -1.8 -0.8 -2.0 -2.2 -1.5 -2.0 -1.5 -1.4 -2.5 -2.1 -1.5 -1.4 -1.5 -1.9 -1.8 -1.3 -2.2 -1.1 -1.5 -1.3 -1.4 -1.5 -1.7 -1.9
Alcohol drinker status: Previous 1.4 1.6 4.8 -0.7 -0.3 -0.9 -1.7 -1.7 -0.5 -1.3 -0.7 -1.5 0.0 -1.4 -0.8 -1.5 -0.8 -1.8 -1.4 -1.5 -1.2 -0.9 -1.6 -1.4 -1.3 -0.5 -0.6 -1.7 -1.1 -2.1 -1.5 -1.6 -1.1 -0.7 -1.4 -1.5 -2.2 -0.9 -0.6 -0.6 -1.6 -1.6 -1.1 -1.6 -1.6 -1.0 -1.0 -0.9 -0.9 -1.2 -1.1
Pack years of smoking 3.9 5.7 10.9 -1.7 -1.5 -2.2 -3.2 -3.1 -1.0 -2.5 -1.2 -3.0 0.0 -2.8 -2.5 -2.8 -2.3 -3.2 -2.6 -2.8 -2.8 -2.3 -3.1 -3.3 -2.6 -1.7 -1.9 -3.0 -0.8 -2.9 -2.2 -2.2 -2.1 -1.6 -2.9 -2.4 -2.0 -2.1 -1.6 -2.1 -1.4 -2.6 -2.1 -1.1 -3.2 -2.1 -2.1 -2.2 -2.8 -3.0 -2.1
Impedance of whole body 0.1 0.4 1.4 1.0 0.7 1.1 0.6 0.6 -0.4 0.5 0.8 0.7 0.0 -0.0 0.6 0.7 0.1 0.3 0.9 0.8 0.1 0.5 0.3 1.2 0.3 -0.4 -0.6 0.3 -0.2 0.1 -0.8 1.0 -0.0 -0.3 0.8 -1.1 -0.2 0.1 0.2 0.3 0.7 0.3 0.8 0.3 1.1 0.1 -0.0 0.3 0.2 0.6 0.0
Leg fat mass (left) 0.1 0.5 3.3 -0.2 0.1 -1.3 -0.9 -0.9 1.8 -0.1 0.6 -0.6 0.0 -0.8 -0.4 -0.9 -0.2 -0.8 -0.2 -0.4 -0.5 0.4 -0.9 -1.7 -0.8 0.0 0.0 -0.9 1.1 -0.6 -0.5 -0.4 -0.4 0.4 -0.5 -0.1 -0.1 -0.1 -0.0 -0.1 -1.1 -0.4 -0.2 -0.5 -0.7 -0.1 -0.1 -0.1 -0.3 -1.3 -0.2
Arm predicted mass (left) 0.1 0.7 3.0 0.8 0.9 -0.2 0.3 0.2 1.7 1.1 1.2 0.7 0.0 0.6 0.6 0.1 0.9 0.5 0.7 0.8 0.6 1.5 0.4 -0.2 1.0 1.2 1.2 0.3 1.1 0.6 0.3 0.9 0.7 1.0 0.7 1.4 0.8 1.0 0.9 0.9 -0.3 0.8 0.8 0.3 0.3 0.8 1.2 0.9 1.0 0.3 1.1