Best TWAS P=4.01e-08 · Best GWAS P=2.23e-07 conditioned to 0.142
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | SLC35E2 | 0.35 | 0.15 | enet | 24 | 0.17 | 1.0e-20 | -4.6 | 5.2 | 1.9e-07 | 0.71 | 0.12 | 0.86 | FALSE |
2 | GTEx | Muscle Skeletal | NADK | 0.06 | 0.00 | enet | 9 | 0.00 | 1.3e-01 | -4.7 | -5.5 | 4.1e-08 | -0.77 | 0.04 | 0.85 | TRUE |
3 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | SLC35E2 | 0.03 | 0.00 | blup | 34 | 0.01 | 5.3e-02 | -4.7 | 5.5 | 4.0e-08 | 0.81 | 0.01 | 0.58 | FALSE |