[Hub]/) : Traits : Comparative body size at age 10 :

chr2:15,703-1,384,725

Best TWAS P=8.95e-16 · Best GWAS P=4.97e-83 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex FAM110C 0.09 0.00 bslmm 232 0.01 8.2e-03 3.2 5.3 1.1e-07 -0.05 0.41 0.02 FALSE
2 GTEx Adipose Subcutaneous TMEM18 0.32 0.21 lasso 9 0.25 4.7e-20 6.4 7.5 5.1e-14 -0.23 1.00 0.00 FALSE
3 GTEx Adipose Subcutaneous AC092159.2 0.29 0.14 lasso 14 0.19 4.2e-15 4.2 6.6 3.5e-11 -0.17 1.00 0.00 FALSE
4 GTEx Adipose Visceral Omentum TMEM18 0.23 0.14 lasso 4 0.17 5.7e-09 6.0 5.9 4.6e-09 -0.15 0.99 0.00 TRUE
5 GTEx Artery Aorta TMEM18 0.32 0.16 lasso 5 0.15 1.4e-08 6.4 6.8 8.8e-12 -0.19 1.00 0.00 FALSE
6 GTEx Artery Aorta AC092159.2 0.29 0.19 enet 9 0.23 9.7e-13 6.2 6.8 1.2e-11 -0.19 1.00 0.00 TRUE
7 GTEx Artery Tibial SH3YL1 0.10 0.02 lasso 3 0.01 2.9e-02 -3.2 -5.9 3.4e-09 0.09 0.65 0.02 FALSE
8 GTEx Artery Tibial TMEM18 0.35 0.08 enet 28 0.19 9.2e-15 6.2 6.5 7.1e-11 -0.19 1.00 0.00 FALSE
9 GTEx Artery Tibial AC092159.2 0.38 0.24 lasso 5 0.30 5.6e-24 5.4 6.6 5.0e-11 -0.19 1.00 0.00 FALSE
10 GTEx Cells Transformed fibroblasts TMEM18 0.30 0.17 enet 10 0.23 2.5e-17 6.0 5.3 1.1e-07 -0.11 1.00 0.00 TRUE
11 GTEx Cells Transformed fibroblasts AC092159.2 0.26 0.17 enet 5 0.21 1.8e-15 6.0 6.0 1.9e-09 -0.16 1.00 0.00 FALSE
12 GTEx Esophagus Mucosa TMEM18 0.37 0.20 lasso 7 0.20 2.3e-13 6.4 6.7 1.5e-11 -0.20 1.00 0.00 FALSE
13 GTEx Esophagus Mucosa AC092159.2 0.27 0.18 enet 5 0.20 2.5e-13 6.0 6.9 7.0e-12 -0.20 1.00 0.00 FALSE
14 GTEx Esophagus Muscularis TMEM18 0.37 0.20 lasso 8 0.18 2.0e-11 5.4 7.8 8.2e-15 -0.28 1.00 0.00 FALSE
15 GTEx Esophagus Muscularis AC092159.2 0.26 0.16 enet 7 0.20 5.3e-12 5.4 6.6 3.6e-11 -0.30 1.00 0.00 FALSE
16 GTEx Heart Atrial Appendage TMEM18 0.26 0.16 lasso 7 0.09 5.0e-05 6.4 6.8 1.2e-11 -0.24 0.86 0.04 FALSE
17 GTEx Heart Left Ventricle TMEM18 0.22 0.19 lasso 7 0.16 8.3e-09 6.0 8.0 8.9e-16 -0.19 0.99 0.00 TRUE
18 GTEx Heart Left Ventricle AC092159.2 0.35 0.24 lasso 6 0.23 2.3e-12 6.0 7.0 2.5e-12 -0.20 1.00 0.00 FALSE
19 GTEx Lung TMEM18 0.13 0.11 lasso 2 0.10 4.5e-08 6.0 6.0 1.7e-09 -0.17 0.99 0.00 FALSE
20 GTEx Lung AC092159.2 0.22 0.17 lasso 3 0.18 1.1e-13 6.0 6.1 1.3e-09 -0.13 1.00 0.00 FALSE
21 GTEx Muscle Skeletal TMEM18 0.40 0.30 lasso 7 0.33 2.0e-33 5.4 5.9 4.5e-09 -0.17 1.00 0.00 FALSE
22 GTEx Muscle Skeletal AC092159.2 0.46 0.34 enet 18 0.39 1.1e-40 5.4 6.1 1.3e-09 -0.17 1.00 0.00 TRUE
23 GTEx Nerve Tibial TMEM18 0.22 0.01 lasso 8 0.05 3.2e-04 6.4 5.5 3.5e-08 -0.21 0.64 0.02 FALSE
24 GTEx Nerve Tibial AC092159.2 0.18 0.09 lasso 5 0.10 1.5e-07 5.4 5.9 4.3e-09 -0.16 0.99 0.00 FALSE
25 GTEx Ovary SH3YL1 0.48 0.29 enet 18 0.34 3.2e-09 -3.1 -6.4 2.0e-10 0.15 0.66 0.04 TRUE
26 GTEx Skin Sun Exposed Lower leg AC092159.2 0.18 0.10 enet 15 0.13 1.4e-10 5.4 5.1 2.7e-07 -0.08 0.99 0.00 TRUE
27 METSIM Adipose TMEM18 0.20 0.12 lasso 6 0.12 9.2e-17 6.0 6.5 1.0e-10 -0.19 1.00 0.00 FALSE
28 The Cancer Genome Atlas Bladder Urothelial Carcinoma TMEM18 0.06 0.04 lasso 3 0.04 2.8e-04 6.0 5.3 1.1e-07 -0.11 0.14 0.14 FALSE
29 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma TMEM18 0.12 0.05 blup 74 0.04 3.1e-05 6.0 6.0 2.0e-09 -0.19 0.59 0.02 TRUE
30 The Cancer Genome Atlas Stomach Adenocarcinoma TMEM18 0.11 0.01 blup 74 0.04 1.3e-03 6.4 7.4 1.3e-13 -0.23 0.11 0.03 FALSE