Best TWAS P=2.88e-08 · Best GWAS P=1.41e-10 conditioned to 0.776
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Cells Transformed fibroblasts | INADL | 0.15 | 0.06 | lasso | 5 | 0.05 | 0.00017 | 5.3 | -5.4 | 5.4e-08 | 0.81 | 0.06 | 0.46 | FALSE |
2 | GTEx | Esophagus Muscularis | TM2D1 | 0.12 | 0.03 | lasso | 3 | 0.04 | 0.00319 | 3.8 | 5.4 | 7.0e-08 | -0.55 | 0.02 | 0.85 | TRUE |
3 | NTR | Blood | INADL | 0.02 | 0.01 | bslmm | 660 | 0.01 | 0.00014 | 3.9 | 5.5 | 2.9e-08 | -0.65 | 0.15 | 0.78 | TRUE |