Best TWAS P=4.02e-15 · Best GWAS P=1.15e-24 conditioned to 2.1e-13
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | METSIM | Adipose | ADCY9 | 0.07 | 0.02 | bslmm | 409 | 0.04 | 1.0e-06 | 1.6 | 7.6 | 2.8e-14 | -0.44 | 0.52 | 0.46 | TRUE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | RP11-462G12.1 | 0.11 | 0.07 | enet | 18 | 0.06 | 1.1e-08 | -10.2 | -7.8 | 4.0e-15 | 0.86 | 0.00 | 1.00 | TRUE |
| 3 | The Cancer Genome Atlas | Cervical Squamous Cell Carcinoma | NLRC3 | 0.07 | 0.02 | blup | 39 | 0.01 | 7.4e-02 | -4.5 | -5.5 | 3.5e-08 | -0.12 | 0.02 | 0.69 | FALSE |
| 4 | The Cancer Genome Atlas | Colon Adenocarcinoma | BTBD12 | 0.05 | 0.01 | blup | 41 | 0.02 | 1.5e-02 | -4.5 | 5.6 | 2.6e-08 | 0.14 | 0.01 | 0.52 | TRUE |