[Hub]/) : Traits : Comparative body size at age 10 : ← →

chr15:66,998,610-68,825,675

Best TWAS P=1.46e-22 · Best GWAS P=6.12e-29 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
20	METSIM	Adipose	MAP2K5	0.07	0.05	enet	19	0.06	2.8e-09	-9.4	9.8	1.5e-22	-0.84	0.14	0.86	TRUE
24	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	MAP2K5	0.03	0.03	blup	142	0.02	1.6e-03	-7.7	9.3	1.5e-20	-0.90	0.05	0.92	TRUE
22	NTR	Blood	MAP2K5	0.02	0.00	enet	13	0.01	5.7e-04	-7.1	8.1	5.1e-16	-0.73	0.25	0.71	TRUE
16	GTEx	Skin Sun Exposed Lower leg	MAP2K5	0.13	0.06	lasso	4	0.09	4.4e-08	6.1	7.8	8.7e-15	-0.67	0.94	0.05	TRUE
18	GTEx	Thyroid	MAP2K5	0.11	0.16	lasso	4	0.15	9.6e-12	-7.6	7.5	6.6e-14	-0.79	0.98	0.02	TRUE
7	GTEx	Brain Hippocampus	IQCH-AS1	0.20	0.08	enet	11	0.05	2.2e-02	6.2	-7.3	3.5e-13	0.48	0.17	0.11	TRUE
17	GTEx	Spleen	MAP2K5	0.25	0.19	lasso	3	0.18	2.1e-05	-7.6	6.8	1.2e-11	-0.77	0.07	0.87	TRUE
27	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	IQCH	0.11	0.10	blup	112	0.10	2.3e-07	-5.8	6.0	2.4e-09	-0.60	0.03	0.97	TRUE
26	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	IQCH	0.04	0.02	enet	6	0.03	1.6e-04	-7.3	5.6	2.1e-08	-0.71	0.18	0.64	TRUE
28	The Cancer Genome Atlas	Soft Tissue Sarcoma	LBXCOR1	0.07	0.03	blup	57	0.03	6.3e-03	-8.3	5.4	6.8e-08	-0.26	0.04	0.09	TRUE
8	GTEx	Breast Mammary Tissue	MAP2K5	0.14	0.07	lasso	5	0.09	2.8e-05	-9.4	9.3	1.0e-20	-0.88	0.04	0.96	FALSE
13	GTEx	Muscle Skeletal	MAP2K5	0.08	0.03	lasso	6	0.05	1.9e-05	8.0	9.3	1.7e-20	-0.71	0.88	0.11	FALSE
10	GTEx	Heart Atrial Appendage	MAP2K5	0.16	0.08	lasso	5	0.16	1.3e-07	-7.6	9.3	2.2e-20	-0.78	0.45	0.54	FALSE
30	The Cancer Genome Atlas	Thyroid Carcinoma	MAP2K5	0.10	0.06	lasso	5	0.04	6.1e-05	-7.7	8.2	2.4e-16	-0.83	0.59	0.37	FALSE
11	GTEx	Heart Left Ventricle	MAP2K5	0.10	0.10	lasso	3	0.10	9.4e-06	-7.6	8.0	1.0e-15	-0.81	0.75	0.18	FALSE
1	CommonMind	Brain Pre-frontal Cortex	MAP2K5	0.11	0.07	bslmm	474	0.08	1.2e-09	-7.7	7.9	2.0e-15	-0.72	0.97	0.03	FALSE
25	The Cancer Genome Atlas	Lung Adenocarcinoma	MAP2K5	0.04	0.04	lasso	3	0.03	8.7e-05	-7.6	7.8	4.9e-15	-0.80	0.11	0.86	FALSE
3	GTEx	Adipose Visceral Omentum	MAP2K5	0.07	0.08	lasso	3	0.05	1.0e-03	-7.3	7.8	8.7e-15	-0.80	0.05	0.91	FALSE
2	GTEx	Adipose Subcutaneous	MAP2K5	0.14	0.18	lasso	4	0.18	1.0e-14	-7.6	7.6	3.0e-14	-0.78	1.00	0.00	FALSE
14	GTEx	Nerve Tibial	MAP2K5	0.19	0.21	lasso	2	0.20	3.3e-14	-7.6	7.6	3.1e-14	-0.78	1.00	0.00	FALSE
15	GTEx	Ovary	MAP2K5	0.19	0.24	lasso	3	0.21	8.3e-06	-7.6	7.6	4.0e-14	-0.78	0.18	0.57	FALSE
23	YFS	Blood	MAP2K5	0.05	0.07	lasso	4	0.07	1.2e-21	-7.6	7.5	4.8e-14	-0.79	1.00	0.00	FALSE
5	GTEx	Artery Tibial	MAP2K5	0.15	0.18	lasso	3	0.18	6.3e-14	-7.6	7.5	7.5e-14	-0.78	1.00	0.00	FALSE
9	GTEx	Esophagus Muscularis	MAP2K5	0.24	0.14	lasso	4	0.13	2.1e-08	-7.6	7.5	8.6e-14	-0.78	1.00	0.00	FALSE
29	The Cancer Genome Atlas	Thyroid Carcinoma	LBXCOR1	0.06	0.01	lasso	3	0.03	7.0e-04	-8.4	7.4	1.5e-13	-0.65	0.10	0.48	FALSE
4	GTEx	Artery Aorta	MAP2K5	0.06	0.05	enet	6	0.05	7.7e-04	-7.6	7.2	5.2e-13	-0.79	0.29	0.55	FALSE
12	GTEx	Lung	MAP2K5	0.12	0.09	enet	11	0.07	3.6e-06	-7.6	6.6	4.4e-11	-0.72	0.97	0.01	FALSE
19	GTEx	Whole Blood	MAP2K5	0.09	0.06	lasso	6	0.06	8.1e-06	-7.6	6.2	7.4e-10	-0.75	0.59	0.30	FALSE
6	GTEx	Brain Cerebellum	MAP2K5	0.27	0.12	lasso	5	0.14	7.9e-05	-3.2	5.9	3.7e-09	-0.67	0.30	0.42	FALSE
21	METSIM	Adipose	SKOR1	0.09	0.03	enet	27	0.04	2.6e-07	-7.1	5.2	2.0e-07	-0.40	0.87	0.09	FALSE