[Hub]/) : Traits : Comparative body size at age 10 :

chr16:66,542,957-68,674,788

Best TWAS P=7.64e-13 · Best GWAS P=8.55e-13 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous ELMO3 0.14 0.04 lasso 3 0.04 5.6e-04 5.0 6.6 4.8e-11 0.83 0.09 0.86 FALSE
2 GTEx Adipose Subcutaneous LRRC29 0.05 0.00 lasso 5 0.00 3.9e-01 6.9 -6.3 3.7e-10 -0.78 0.04 0.41 FALSE
3 GTEx Adipose Visceral Omentum ATP6V0D1 0.12 0.03 lasso 6 0.03 8.3e-03 6.8 -6.4 1.7e-10 -0.83 0.03 0.75 FALSE
4 GTEx Artery Aorta ELMO3 0.08 0.04 enet 16 0.06 4.4e-04 5.0 5.8 6.2e-09 0.67 0.06 0.28 FALSE
5 GTEx Lung LRRC29 0.06 0.02 enet 11 0.03 4.7e-03 6.6 -6.6 5.1e-11 -0.90 0.03 0.82 FALSE
6 GTEx Muscle Skeletal ATP6V0D1 0.11 0.03 enet 13 0.04 4.8e-05 7.2 -7.2 7.6e-13 -0.96 0.01 0.99 TRUE
7 GTEx Pituitary LCAT 0.13 0.10 enet 10 0.04 3.9e-02 -3.8 5.5 3.2e-08 0.46 0.05 0.33 FALSE
8 GTEx Prostate FHOD1 0.36 0.04 lasso 13 0.10 1.8e-03 6.2 5.7 1.6e-08 0.79 0.07 0.52 FALSE
9 GTEx Testis ATP6V0D1 0.43 0.35 enet 12 0.41 1.9e-19 6.6 -6.3 2.5e-10 -0.95 0.08 0.92 FALSE
10 YFS Blood E2F4 0.03 0.02 lasso 7 0.02 2.0e-07 5.1 -5.7 1.1e-08 -0.54 0.97 0.01 FALSE
11 The Cancer Genome Atlas Bladder Urothelial Carcinoma B3GNT9 0.03 0.03 blup 26 0.02 1.3e-02 5.0 5.4 6.5e-08 0.62 0.06 0.41 FALSE
12 The Cancer Genome Atlas Colon Adenocarcinoma LRRC29 0.05 0.05 blup 33 0.05 5.4e-04 5.2 -5.9 3.7e-09 -0.74 0.06 0.85 FALSE
13 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma ATP6V0D1 0.03 0.00 enet 6 0.01 1.1e-02 6.6 -5.4 6.1e-08 -0.79 0.01 0.84 FALSE
14 The Cancer Genome Atlas Thyroid Carcinoma ATP6V0D1 0.04 0.01 enet 5 0.02 3.2e-03 7.0 -6.5 6.0e-11 -0.82 0.00 0.81 FALSE