TWAS hub - ATP6V0D1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1030	0.0350	1.3e-11	0.121	0.091	0.093	0.093	0.111	1.7e-14	3.2e-11	2.1e-11	2.4e-11	2.4e-13
2	GTEx	Adipose Visceral Omentum	0.1170	0.0530	1.9e-03	0.027	NA	0.030	NA	0.032	1.5e-02	NA	1.1e-02	NA	8.3e-03
3	GTEx	Cells Transformed fibroblasts	0.1030	0.0640	6.9e-03	-0.002	NA	0.024	NA	0.001	4.5e-01	NA	6.2e-03	NA	2.7e-01
4	GTEx	Muscle Skeletal	0.1134	0.0381	9.3e-07	0.033	NA	0.042	NA	0.030	3.0e-04	NA	4.9e-05	NA	5.3e-04
5	GTEx	Spleen	0.3550	0.1150	2.4e-03	0.028	NA	0.074	NA	0.045	6.6e-02	NA	6.0e-03	NA	2.6e-02
6	GTEx	Testis	0.4290	0.0730	7.2e-14	0.348	NA	0.408	NA	0.358	3.2e-16	NA	1.9e-19	NA	1.0e-16
7	GTEx	Whole Blood	0.0830	0.0410	1.4e-03	0.002	NA	-0.001	NA	-0.002	2.2e-01	NA	3.6e-01	NA	5.0e-01
8	METSIM	Adipose	0.1331	0.0445	4.7e-08	0.026	0.063	0.068	0.074	0.069	7.3e-05	9.5e-10	1.9e-10	3.5e-11	1.7e-10
9	NTR	Blood	0.0167	0.0089	4.7e-04	0.013	0.010	0.005	0.011	0.008	2.6e-05	2.9e-04	7.1e-03	1.6e-04	8.2e-04
10	YFS	Blood	0.1445	0.0342	0.0e+00	0.184	0.199	0.196	0.199	0.200	4.5e-58	7.8e-63	6.3e-62	3.6e-63	1.8e-63
11	TCGA	Breast Invasive Carcinoma	0.0124	0.0090	8.4e-03	0.005	0.008	0.003	NA	0.003	2.5e-02	7.1e-03	7.6e-02	NA	6.3e-02
12	TCGA	Head and Neck Squamous Cell Carcinoma	0.0336	0.0208	5.2e-03	-0.001	0.012	0.013	NA	0.008	3.8e-01	1.6e-02	1.1e-02	NA	4.0e-02
13	TCGA	Kidney Renal Clear Cell Carcinoma	0.0380	0.0185	7.2e-06	0.061	0.052	0.041	NA	0.052	2.0e-07	1.5e-06	1.9e-05	NA	1.4e-06
14	TCGA	Lung Adenocarcinoma	0.0354	0.0190	3.7e-05	0.024	0.026	0.012	NA	0.021	6.7e-04	4.7e-04	1.2e-02	NA	1.3e-03
15	TCGA	Lung Squamous Cell Carcinoma	0.0421	0.0276	4.9e-03	0.001	0.003	0.004	NA	0.001	2.4e-01	1.2e-01	9.3e-02	NA	2.1e-01
16	TCGA	Thyroid Carcinoma	0.0390	0.0270	7.3e-03	0.010	0.016	0.022	NA	0.014	3.2e-02	9.4e-03	3.2e-03	NA	1.3e-02

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	4	5	6	7	8	9	10	11	12	13	14	15	16
Hair/balding pattern: Pattern 4	16.5	39.9	69.5	7.9	4.9	1.8	8.3	2.1	7.9	6.1	8.0	7.7	7.1	2.0	7.3	8.3	7.4	4.3
Lung FEV1/FVC ratio	14.7	74.7	114.5	-9.9	-9.3	-8.2	-9.1	-8.6	-9.4	-6.4	-9.7	-8.9	-10.7	-8.7	-10.1	-9.1	-5.7	-8.8
Hypothyroidism (self reported)	8.8	20.3	40.1	-5.9	-3.0	-0.5	-6.2	-0.6	-5.9	-3.7	-5.7	-6.3	-4.9	-1.7	-5.4	-5.9	-4.7	-2.9
Hypothyroidism/myxoedema (self-reported)	7.6	14.8	28.8	-5.0	-2.8	-0.8	-5.2	-0.7	-4.9	-3.4	-4.6	-5.4	-4.2	-2.0	-4.6	-5.0	-3.9	-2.6
Medication: Levothyroxine sodium	7.1	12.1	22.4	-4.4	-2.6	-0.7	-4.7	-0.9	-4.4	-2.6	-4.2	-4.7	-3.9	-2.4	-4.1	-4.6	-3.3	-2.7
Qualifications: CSEs or equivalent	5.9	7.8	14.6	-3.7	-1.7	-0.7	-3.4	-1.2	-3.4	-1.8	-3.4	-3.8	-3.3	-2.0	-3.4	-3.6	-2.8	-2.5
Comparative body size at age 10	5.7	15.8	51.4	-2.3	-6.4	-7.2	-0.2	-6.3	-1.7	-1.1	-2.0	-1.0	-4.1	-5.4	-3.4	-1.9	-1.4	-6.5
HDL Cholesterol	5.2	8.8	32.9	-1.9	-3.0	-5.0	-4.1	-4.3	-0.5	-5.7	-0.6	-2.2	-1.9	-2.3	-2.0	-1.4	-2.2	-3.0
Waist Hip Ratio (WHR)	5.1	22.8	43.1	6.2	3.2	0.1	6.2	0.5	6.5	4.6	6.3	6.6	5.1	1.9	5.4	6.2	5.2	2.8
Serious illness, injury or assault to yourself	4.6	5.5	9.6	3.0	2.6	1.0	3.1	1.1	2.8	2.4	2.2	3.0	2.6	1.7	2.8	2.9	2.3	1.6
Heel T-Score	4.5	35.8	90.2	-5.9	-4.0	-2.3	-6.0	-2.2	-7.8	-8.3	-9.5	-4.6	-5.7	-2.1	-5.7	-6.9	-9.4	-5.3
Falls in the last year	4.4	6.0	12.6	2.8	3.0	2.3	2.7	2.3	2.4	1.1	2.0	2.7	2.8	3.6	2.8	2.5	1.0	2.8
Bipolar Disorder or Schizophrenia	4.3	10.5	16.5	-3.9	-2.6	-1.3	-3.9	-1.0	-4.1	-4.0	-3.7	-3.7	-3.4	-2.7	-3.8	-3.8	-3.6	-2.7
Number of live births	4.3	6.0	13.7	-2.4	-3.5	-3.7	-2.1	-3.3	-1.7	-1.0	-1.7	-1.8	-3.1	-2.8	-2.6	-2.1	-0.8	-3.3
Pulse rate, automated reading	4.3	14.0	26.8	3.7	5.2	3.9	1.7	4.1	3.6	1.7	3.7	2.9	4.3	4.9	4.1	3.8	3.6	4.9
Schizophrenia (2018)	3.9	8.0	14.7	-3.2	-2.6	-1.8	-3.3	-1.6	-3.3	-3.8	-2.7	-3.0	-3.0	-2.7	-3.4	-3.1	-3.0	-2.6
Heel bone mineral density (BMD) T-score, automated (left)	3.5	8.0	22.1	-2.6	-2.1	-1.8	-2.1	-1.8	-3.4	-3.8	-4.2	-1.6	-3.0	-1.4	-2.7	-3.1	-4.7	-3.1
Ever highly irritable/argumentative for 2 days	3.5	4.2	9.9	2.7	1.4	-0.2	2.4	0.4	3.1	1.1	2.8	2.8	2.2	0.9	2.4	2.8	2.0	0.9
Forced vital capacity (FVC)	3.4	13.0	20.7	4.3	3.4	3.1	4.0	3.0	3.7	4.6	3.1	4.0	4.4	3.1	4.2	4.0	2.7	3.7
Impedance of leg (right)	3.3	16.2	30.5	5.3	3.2	0.2	4.2	0.6	5.5	2.2	5.5	5.5	4.6	2.2	4.8	5.2	4.3	3.5
Schizophrenia (2014)	3.2	7.0	10.7	-2.9	-2.7	-2.2	-3.0	-1.9	-2.8	-3.2	-2.6	-2.6	-2.8	-3.3	-2.9	-2.7	-2.5	-2.7
Ovarian Cancer	3.1	4.1	6.8	2.3	2.0	1.5	2.4	1.5	2.4	2.2	2.6	2.5	2.1	2.0	2.3	2.1	1.1	2.0
Fasting Glucose	3.1	3.7	7.4	2.3	1.3	1.7	2.7	1.9	2.3	2.0	1.6	2.2	2.0	2.5	1.9	2.0	1.3	1.4
Lung FVC	3.1	15.8	40.4	3.4	5.3	6.4	2.5	6.3	2.4	1.9	3.0	2.5	5.0	4.3	4.1	3.1	1.4	5.5
Heel bone mineral density (BMD) T-score, automated (right)	3.0	6.8	21.5	-2.4	-1.7	-1.3	-2.1	-1.3	-3.3	-3.3	-4.1	-1.5	-2.7	-0.9	-2.5	-3.0	-4.6	-2.6
Impedance of leg (left)	2.9	14.3	28.2	5.0	2.8	-0.3	4.0	0.2	5.2	1.4	5.3	5.3	4.2	2.3	4.5	5.1	3.8	3.1
Alcohol usually taken with meals	2.9	4.7	8.0	-2.7	-2.0	-0.9	-2.8	-1.1	-2.7	-1.1	-2.8	-2.7	-2.4	-2.5	-2.5	-2.7	-1.1	-1.8
Alcohol intake versus 10 years previously	2.9	4.4	8.7	2.9	1.1	-0.2	2.6	0.3	3.0	2.1	2.6	2.9	2.2	1.4	2.4	2.9	1.9	1.1
Average weekly champagne plus white wine intake	2.9	4.0	10.3	-2.0	-3.2	-2.7	-1.4	-2.6	-1.4	-1.4	-1.7	-1.7	-2.3	-2.4	-2.1	-1.8	-0.6	-2.4
Alzheimer’s Disease (in father)	2.8	3.0	7.9	-2.3	-1.0	-0.3	-2.8	-0.6	-1.9	-1.4	-1.6	-2.2	-2.1	-0.7	-2.1	-2.2	-1.6	-1.8
Prostate Cancer	2.8	4.0	8.8	2.1	2.1	1.7	1.7	1.5	2.0	1.6	1.6	2.0	2.0	3.0	2.1	2.1	2.1	2.7
Impedance of whole body	2.8	14.3	29.6	4.8	3.5	0.7	3.4	1.1	5.2	1.6	5.4	4.6	4.3	2.4	4.5	4.8	4.6	3.4
Prospective memory result	2.7	3.3	8.1	-1.3	-2.6	-2.9	-1.8	-2.6	-1.2	-1.6	-1.4	-0.8	-1.9	-2.1	-1.7	-1.3	-0.8	-2.5
Fractured/broken bones in last 5 years	2.7	3.5	5.8	2.3	1.7	0.7	2.1	0.7	2.1	2.2	2.2	2.1	2.1	1.1	2.1	2.4	2.4	1.7
Blood Red Count	2.6	24.8	81.0	-6.1	-0.8	-0.5	-9.0	-1.4	-6.1	-5.5	-7.4	-6.8	-4.8	-0.9	-5.1	-5.7	-4.5	-2.2
Glaucoma (self-reported)	2.6	3.0	5.4	1.9	1.8	1.6	1.7	1.7	1.9	1.6	2.1	1.4	2.1	1.6	1.8	1.9	1.4	2.3
Reproduciblity of spirometry measurement using ERS/ATS criteria	2.6	3.1	5.2	-1.8	-1.7	-1.3	-1.4	-1.8	-2.2	-2.2	-1.8	-1.5	-2.2	-0.7	-2.1	-1.7	-2.3	-1.6
Number of full sisters	2.4	3.0	8.8	1.9	1.4	1.3	1.6	1.8	2.0	0.7	3.0	1.6	1.9	1.6	1.9	2.0	2.1	0.8
Illnesses of siblings	2.3	3.3	5.8	-2.0	-2.4	-1.9	-1.5	-1.8	-1.7	0.0	-1.9	-1.7	-2.0	-1.9	-2.0	-2.0	-2.0	-2.1
Forced vital capacity (FVC), Best measure	2.3	8.6	13.0	3.3	2.6	2.7	3.3	2.8	2.9	3.5	2.6	3.0	3.6	2.6	3.4	3.3	2.0	3.2
Neck or shoulder pain in last month	2.3	3.3	9.0	-1.8	-2.4	-2.2	-1.9	-2.0	-1.4	-1.5	-1.4	-1.3	-2.3	-1.3	-1.9	-1.6	-1.1	-3.0
Comparative height size at age 10	2.3	12.4	31.2	4.5	0.0	-3.3	5.3	-2.6	4.5	4.4	3.1	5.6	2.6	-0.9	3.3	4.6	3.5	0.5
Osteoporosis (self-reported)	2.3	2.8	6.0	1.7	1.7	1.2	1.8	1.0	1.9	2.4	2.1	1.2	1.8	0.7	1.7	1.7	1.9	2.5
Eye problems/disorders: Glaucoma	2.3	2.7	4.4	1.6	1.9	1.9	1.7	2.0	1.6	1.5	1.7	1.1	1.9	1.7	1.7	1.5	1.3	2.1
Medication: Bendroflumethiazide	2.3	3.4	8.1	2.3	1.6	0.6	2.3	0.8	2.3	0.3	2.9	2.2	2.2	0.4	2.2	2.5	2.1	1.3
Happiness	2.2	2.7	6.2	2.3	1.2	-0.6	2.5	-0.4	2.1	1.1	2.1	2.5	1.7	0.3	1.9	2.2	1.4	0.7
Family relationship satisfaction	2.2	2.7	8.3	2.4	0.8	-0.7	2.3	-0.8	2.2	1.1	1.9	2.9	1.6	0.1	1.9	2.2	1.3	0.2
Current tobacco smoking	2.1	3.4	15.0	0.6	-2.6	-3.9	1.2	-3.7	1.1	0.9	1.3	1.4	-0.8	-2.3	-0.1	1.1	1.0	-1.7
Pulse rate	2.1	3.6	6.0	2.2	2.2	1.0	1.6	1.2	2.3	1.0	1.8	1.8	2.2	2.4	2.2	2.3	2.1	2.0
Knee pain experienced in last month	2.1	3.3	10.4	-1.2	-2.3	-3.1	-1.6	-3.2	-0.7	-1.2	-0.9	-0.7	-1.9	-2.4	-1.6	-0.9	-0.3	-2.8
Heart disease (siblings)	2.1	2.6	4.1	2.0	1.9	1.2	1.1	1.6	1.7	1.4	1.3	1.7	1.8	1.7	2.0	2.0	1.9	1.0
Suffer from ‘nerves’	2.0	3.1	6.5	-2.4	-1.1	-0.5	-2.5	-0.7	-1.8	-2.1	-2.1	-2.5	-2.1	-0.9	-2.2	-2.4	-1.1	-0.7
Supplements: Fish oil (including cod liver oil)	2.0	2.7	7.5	-1.5	-1.7	-1.9	-1.0	-2.0	-1.6	-0.1	-1.8	-1.0	-2.2	-1.5	-1.9	-1.5	-1.4	-2.7
Bipolar Disorder (2018)	1.9	3.0	6.5	-2.3	-0.9	0.1	-2.2	0.2	-2.4	-1.7	-2.6	-2.2	-1.7	-0.3	-1.8	-2.1	-2.0	-1.3
Schizophrenia vs Biploar Disorder	1.9	2.5	11.4	-0.6	-1.6	-2.7	-0.5	-2.9	-0.2	-0.2	-0.1	-0.3	-1.2	-3.4	-1.0	-0.3	1.3	-2.4
Diabetes (mother)	1.9	2.5	8.2	-1.4	-2.2	-2.9	-1.1	-2.8	-0.5	-1.1	-1.2	-0.7	-2.1	-0.8	-1.7	-1.2	-1.1	-0.9
Impedance of arm (right)	1.9	8.9	22.2	3.5	3.2	0.8	2.3	1.0	4.1	1.0	4.7	3.3	3.4	1.6	3.4	3.7	4.1	2.6
Impedance of arm (left)	1.9	8.6	19.5	3.4	3.1	1.1	2.2	1.4	4.0	1.2	4.4	3.0	3.4	2.0	3.4	3.5	4.2	2.7
Chronic bronchitis/emphysema (mother)	1.9	2.3	9.6	-1.8	-1.5	-0.6	-1.6	-0.6	-1.4	-3.1	-0.5	-1.8	-1.7	-0.1	-1.7	-1.5	-1.9	-0.6
Smoking status: Current	1.9	3.0	12.1	0.7	-2.2	-3.5	1.2	-3.3	1.2	0.8	1.8	1.4	-0.6	-2.2	-0.0	1.2	1.1	-1.4
Hair/balding pattern: Pattern 3	1.8	2.7	6.1	-2.1	-1.3	0.3	-1.4	-0.0	-2.3	-0.4	-2.0	-2.2	-1.6	-1.7	-1.9	-2.5	-2.2	-0.8
Standing height	1.8	18.2	50.7	5.5	-0.2	-3.6	6.1	-3.4	5.1	7.1	1.9	7.0	3.2	-0.5	4.1	5.2	4.0	0.1
Medication: Seretide 50 evohaler	1.8	2.1	6.3	1.6	0.1	0.6	2.5	0.6	1.7	1.2	2.0	1.9	1.4	1.7	1.5	1.6	0.4	1.4
Blood White Count	1.7	12.7	26.1	4.2	2.2	1.1	3.3	1.6	5.1	2.7	5.1	4.0	4.0	2.6	4.3	4.5	4.9	2.3
Time employed in main current job	1.7	1.9	7.8	-1.5	-0.1	0.6	-1.7	0.7	-1.9	-1.0	-2.8	-1.6	-1.1	1.4	-1.2	-1.7	-1.7	0.0
Loneliness, isolation	1.7	2.4	9.4	-0.9	-2.6	-3.1	-0.8	-2.8	-0.3	-1.1	-0.3	-0.4	-1.6	-1.7	-1.2	-0.5	-0.3	-1.9
Pain type(s) experienced in last month: Hip pain	1.7	2.1	4.5	-1.5	-1.6	-1.5	-2.1	-1.4	-1.3	-1.5	-1.3	-1.3	-1.7	-1.3	-1.5	-1.3	-0.4	-2.1
Myopia	1.7	2.5	6.2	-1.8	-0.4	0.4	-2.5	0.0	-2.4	-2.2	-2.2	-2.0	-1.4	-0.7	-1.6	-1.9	-1.5	-0.3
Health satisfaction	1.6	2.1	4.9	1.7	1.4	0.6	1.4	0.9	1.9	0.9	1.3	1.5	1.7	1.2	1.7	1.6	1.4	2.2
Average weekly red wine intake	1.6	2.4	8.3	-0.7	-2.1	-2.9	0.5	-2.7	-0.7	0.3	-0.8	0.1	-1.6	-2.3	-1.2	-0.6	-0.1	-2.5
Irritability	1.6	2.7	5.1	-1.6	-1.7	-2.2	-1.9	-2.3	-1.2	-1.0	-0.9	-1.3	-2.2	-2.1	-1.9	-1.4	-0.0	-2.3
Alzheimer’s Disease (in mother)	1.5	1.7	3.7	1.5	1.6	1.0	1.0	1.1	1.6	0.1	1.9	1.4	1.7	0.8	1.6	1.6	0.8	1.5
Deep venous thrombosis (DVT) (self-reported)	1.5	1.9	6.7	-1.3	-1.7	-1.8	-1.7	-1.7	-0.5	0.4	-1.1	-1.3	-1.3	-2.6	-1.3	-1.1	0.4	-1.5
Height	1.4	27.3	76.0	6.9	0.2	-4.6	7.0	-4.3	6.3	7.8	3.2	8.7	3.9	0.3	5.2	6.8	5.1	-0.2
Average weekly spirits intake	1.4	1.8	3.4	1.6	1.3	0.7	1.8	0.7	1.5	1.8	1.5	1.6	1.3	1.3	1.5	1.5	0.9	0.9
Tinnitus: Yes, but not now, but have in the past	1.4	1.5	5.4	0.7	2.3	2.3	0.1	2.0	0.3	0.8	0.2	0.3	1.0	1.8	1.0	0.7	1.2	0.9
Fluid intelligence score	1.4	3.0	4.7	1.8	2.0	2.2	2.0	2.2	1.6	1.3	2.1	1.6	2.1	1.2	1.9	1.6	0.4	1.9
Mouth/teeth dental problems: Bleeding gums	1.4	1.8	7.1	0.1	-1.6	-2.6	-0.6	-2.2	-0.3	-0.8	-0.6	0.7	-0.9	-2.2	-0.5	-0.0	-0.4	-2.7
Age at first live birth	1.4	2.5	10.4	0.6	2.6	3.2	0.1	3.0	0.2	-0.1	0.3	-0.1	1.7	2.0	1.2	0.4	-0.3	1.9
Emphysema/chronic bronchitis	1.4	1.6	5.0	1.3	1.5	1.1	2.2	1.1	1.5	0.7	1.7	1.1	1.3	0.7	1.3	1.2	0.9	1.3
Friendships satisfaction	1.4	1.8	6.0	2.1	0.9	-0.6	1.8	-0.5	1.5	0.4	1.5	2.4	1.5	0.1	1.6	1.9	0.7	0.2
Guilty feelings	1.4	2.1	7.7	-0.3	-2.1	-2.8	-0.0	-2.6	0.3	0.7	0.3	0.1	-1.2	-2.4	-0.7	-0.0	1.0	-2.2
Commuting to job workplace: Public transport	1.4	1.7	2.8	1.6	0.9	1.2	1.6	1.6	1.3	-0.1	1.6	1.5	1.7	1.4	1.6	1.4	0.5	1.1
Pain experienced in last month	1.4	2.3	11.2	0.3	2.2	3.3	0.6	2.9	-0.2	0.3	0.0	-0.3	1.3	1.5	0.8	-0.1	-1.2	2.5
Financial difficulties in last 2 years	1.3	1.8	5.1	1.0	-1.2	-2.3	0.9	-2.1	1.6	0.1	2.1	1.3	0.3	-1.1	0.6	1.6	1.5	-0.9
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.3	1.5	4.0	1.6	0.5	-0.2	1.4	0.1	1.6	-0.1	1.7	2.0	1.1	1.3	1.3	1.6	1.0	1.0
Medication: Omeprazole (e.g. Zanprol)	1.3	1.6	5.6	1.3	-0.7	-1.9	1.0	-1.7	1.3	1.0	1.2	1.8	0.3	-0.2	0.8	1.6	2.4	0.1
Mean Putamen Volume	1.2	1.4	3.4	-1.6	-0.4	0.4	-1.0	0.3	-1.5	-0.8	-1.9	-1.6	-1.2	-0.2	-1.4	-1.8	-1.8	0.5
BMI	1.2	6.8	15.8	-3.2	-4.0	-2.4	-1.9	-2.2	-2.8	-0.5	-2.9	-2.9	-3.4	-1.7	-3.1	-2.7	-1.6	-3.2
Medication: Paracetamol	1.2	2.0	4.9	1.7	-0.5	-1.7	1.6	-1.5	1.9	1.2	1.8	2.2	0.7	-0.6	1.2	1.7	1.7	-0.3
Medication: Omeprazole	1.2	1.4	3.9	1.3	-0.9	-2.0	1.1	-1.6	1.4	1.1	1.0	1.8	0.4	0.2	0.8	1.5	1.5	0.3
Smoking status: Previous	1.2	1.8	5.4	-0.8	1.7	2.3	-1.5	2.2	-1.5	-1.6	-1.4	-1.1	-0.0	1.3	-0.3	-0.9	-1.3	0.3
Bipolar Disorder (2011)	1.1	1.0	10.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	-2.6	0.0	0.0	-3.2	0.0	0.0
Body Mass Index (BMI) (2010)	1.1	1.5	3.4	-1.8	-0.6	0.4	-1.1	0.2	-1.8	-0.2	-1.7	-1.8	-1.5	0.1	-1.6	-1.7	-1.2	-0.8
Blood Eosinophil Count	1.1	8.4	31.0	1.7	-2.3	-4.8	1.2	-4.3	3.6	2.0	3.7	2.0	0.1	-2.9	0.8	2.5	5.6	-1.6
Blood clot in the leg (DVT)	1.1	1.4	5.4	-1.1	-1.4	-1.5	-1.4	-1.4	-0.4	0.5	-1.0	-1.2	-1.1	-2.3	-1.1	-1.0	0.2	-1.2
Overall health rating	1.1	2.3	5.0	1.7	1.3	0.4	1.5	0.7	2.2	1.6	1.3	1.5	1.6	1.2	1.7	1.7	2.1	1.9
Leg pain on walking	1.1	1.4	3.9	1.5	0.1	-0.7	2.0	-0.3	1.7	-0.3	1.7	1.7	1.1	1.0	1.3	1.6	0.2	0.6
Mood swings	1.1	2.0	4.8	-1.4	-1.5	-2.2	-1.5	-2.1	-0.8	-0.2	-1.2	-1.3	-1.8	-1.4	-1.6	-1.1	0.4	-1.9
Mineral and other dietary supplements	1.1	1.5	6.0	0.7	1.5	2.0	-0.2	2.1	0.6	0.2	0.7	0.0	1.3	1.2	1.1	0.6	1.0	2.4
Medication: Gliclazide	1.1	1.2	2.6	-1.1	-0.9	-1.0	-1.6	-1.1	-1.1	0.1	-1.3	-0.9	-1.3	-1.5	-1.2	-1.0	0.4	-1.3
Ever taken oral contraceptive pill	1.1	1.2	5.1	-1.1	-0.7	-0.1	-1.3	-0.1	-1.4	-0.4	-1.6	-0.8	-1.1	0.2	-1.0	-1.4	-2.3	-1.0
Tinnitus: Yes, now most or all of the time	1.1	1.3	3.4	-1.5	0.2	0.5	-1.2	0.2	-1.4	-1.0	-0.9	-1.8	-1.1	-0.5	-1.4	-1.7	-1.7	0.0
Medication: Lisinopril	1.1	1.4	5.1	1.3	-0.0	-0.6	1.5	-0.5	1.6	0.7	2.3	1.4	0.8	-1.1	0.9	1.5	1.8	0.1
Reaction Time	1.0	1.9	3.7	1.9	1.2	0.8	1.6	0.9	1.4	-0.1	1.4	1.7	1.9	0.8	1.8	1.8	0.8	1.9
Crohns Disease (2012)	1.0	1.6	5.0	1.3	0.7	1.4	1.5	2.0	0.7	1.8	-0.0	1.2	1.4	2.2	1.2	1.0	0.0	0.8
Hand grip strength (left)	1.0	2.7	6.8	-1.6	-2.6	-1.8	-0.9	-1.6	-1.5	0.7	-2.1	-1.4	-1.9	-1.6	-1.8	-1.6	-1.2	-2.0
Other serious medical condition/disability diagnosed by doctor	1.0	1.3	2.5	1.0	1.5	1.2	1.1	1.2	1.1	1.1	1.2	0.8	1.2	0.5	1.1	1.2	1.6	1.2
Multivitamins +/- minerals	1.0	1.3	2.3	-1.2	-1.3	-1.2	-1.5	-1.1	-1.0	-1.0	-1.2	-1.0	-1.3	-0.3	-1.2	-1.1	-1.1	-1.5
Stomach or abdominal pain in last month	1.0	1.3	2.6	-1.2	-1.2	-1.4	-1.3	-1.5	-0.6	0.0	-0.9	-1.1	-1.5	-1.6	-1.3	-1.0	0.6	-1.1
Hearing difficulty/problems with background noise	1.0	1.6	4.9	0.8	2.2	2.1	0.5	2.0	0.6	-0.6	0.5	0.4	1.3	1.4	1.0	0.5	0.3	2.2
Had other major operations	1.0	1.3	2.3	-1.3	-1.5	-1.5	-1.1	-1.3	-0.8	-0.9	-0.7	-1.3	-1.4	-1.2	-1.4	-1.1	-0.2	-1.0
Mouth/teeth dental problems	1.0	1.6	3.1	0.8	1.5	1.7	0.9	1.6	1.2	1.0	1.7	0.2	1.4	1.2	1.2	1.2	1.8	1.2
Medication: Amlodipine	1.0	1.4	6.7	-0.1	1.8	2.6	-0.6	2.2	-0.2	-0.9	-0.0	-0.8	0.6	0.9	0.4	-0.2	-0.4	2.2
Qualifications: College or University degree	1.0	3.2	7.9	2.4	1.3	0.9	2.8	0.9	1.6	2.8	1.0	2.6	2.2	1.1	2.1	2.1	0.9	0.7
Qualifications: NVQ or HND or HNC or equivalent	1.0	1.2	4.3	0.3	-1.1	-2.1	0.8	-2.0	0.7	0.9	0.7	0.8	-0.3	-1.2	-0.0	0.5	0.4	-2.0
Medication for cholesterol	1.0	1.6	6.0	-1.4	-0.9	0.3	-1.4	-0.0	-1.7	-0.1	-1.5	-1.2	-1.3	1.2	-1.3	-1.6	-2.5	-0.3
Intelligence (Savage-Jansen 2018)	0.9	2.7	7.9	1.3	2.5	2.8	1.7	2.4	0.7	1.1	1.1	1.2	1.9	1.1	1.6	1.0	-0.6	2.1
Medication: Co-codamol	0.9	1.0	1.6	-1.2	-1.1	-0.9	-1.2	-0.9	-1.2	-1.3	-1.1	-1.0	-1.2	-0.4	-1.1	-1.1	-1.1	-0.7
Pack years adult smoking proportion	0.9	1.4	3.3	1.4	0.1	-0.6	1.8	-0.6	1.7	1.1	1.3	1.6	0.9	1.2	1.1	1.5	0.7	1.2
Body mass index (BMI)	0.9	3.8	7.8	-2.3	-2.8	-2.1	-1.3	-1.8	-1.9	-0.8	-2.0	-2.1	-2.7	-1.2	-2.3	-2.0	-1.3	-2.5
Waist circumference	0.9	3.2	7.7	2.0	-0.5	-1.9	2.8	-1.5	2.3	2.3	1.8	2.6	0.8	0.2	1.4	2.2	1.9	-0.5
Serious illness, injury or assault of a close relative in last 2 years	0.9	1.0	3.3	1.0	0.2	0.2	1.8	0.5	1.6	1.3	1.7	0.9	0.9	0.7	0.9	1.0	1.1	0.3
High blood pressure (siblings)	0.9	1.3	5.6	0.7	2.4	1.9	0.2	1.4	0.5	-0.9	0.6	0.5	1.0	1.2	0.8	0.6	0.2	1.9
Shortness of breath walking on level ground	0.9	1.0	2.2	1.0	1.0	0.9	1.0	0.9	1.4	0.4	1.4	0.6	1.1	1.5	1.0	0.9	0.3	1.5
Medication for pain relief, constipation, heartburn	0.9	1.6	5.5	-1.2	1.0	2.0	-0.9	1.6	-1.5	-0.2	-1.6	-1.7	-0.2	0.3	-0.7	-1.2	-2.3	0.6
Ever had stillbirth, spontaneous miscarriage or termination	0.9	1.0	2.4	1.2	0.2	-0.4	1.2	-0.2	1.3	1.6	1.1	1.2	0.9	-0.3	1.1	1.2	1.2	-0.4
Financial situation satisfaction	0.9	1.1	4.0	1.2	-0.5	-1.4	2.0	-1.1	1.4	0.4	1.1	1.5	0.6	0.1	0.8	1.1	0.4	-0.2
Depressed Affect (Nagel 2018)	0.8	1.8	6.5	-0.4	-1.5	-2.5	-0.2	-2.4	0.1	0.5	0.1	-0.1	-1.4	-1.7	-0.9	-0.2	1.5	-2.3
Verbal and Numeric Reasoning (VNR)	0.8	1.8	6.0	1.0	1.5	2.5	1.3	2.3	0.8	0.9	1.4	0.5	1.6	0.7	1.2	0.8	0.4	1.9
Chronotype (morning person)	0.8	1.9	5.4	1.1	-1.5	-1.7	2.1	-1.4	1.3	2.3	0.9	1.7	0.3	-1.4	0.5	1.0	1.2	-1.6
Supplements: Zinc	0.8	0.8	1.6	-1.0	-0.8	-0.9	-1.0	-1.1	-0.9	-0.5	-0.8	-1.0	-1.1	-1.0	-1.0	-0.8	0.5	-1.3
Severe depression (siblings)	0.8	0.9	3.2	-0.4	-1.0	-1.7	0.2	-1.8	0.1	0.9	0.1	-0.1	-0.9	-1.3	-0.7	-0.1	0.6	-1.6
Hand grip strength (right)	0.8	2.2	5.4	-1.4	-2.0	-1.5	-0.7	-1.6	-1.4	0.8	-2.3	-1.3	-1.7	-1.5	-1.6	-1.5	-1.1	-1.8
Neuroticism score	0.8	1.7	4.1	-1.1	-1.4	-2.0	-1.1	-1.9	-0.4	0.2	-0.7	-1.1	-1.7	-2.0	-1.4	-1.0	0.8	-1.7
Qualifications: A levels/AS levels or equivalent	0.8	1.7	4.1	1.6	1.0	1.1	1.4	1.0	0.9	1.3	0.5	1.6	1.4	2.0	1.5	1.4	-0.2	1.9
Birth weight of first child	0.8	1.4	4.2	-1.2	-0.1	0.3	-1.8	0.4	-1.5	-1.0	-1.5	-1.1	-1.0	0.6	-1.2	-1.7	-2.0	-0.9
Seen a psychiatrist for nerves, anxiety, tension or depression	0.8	1.0	1.8	1.3	1.1	0.7	1.0	0.7	1.1	1.2	0.2	1.3	1.2	1.2	1.3	1.0	1.0	0.7
Medication: Blood pressure	0.8	1.4	3.3	1.1	1.7	1.8	0.4	1.6	0.9	0.4	1.2	0.9	1.2	0.5	1.3	1.0	1.1	1.8
Arm predicted mass (right)	0.8	3.8	11.1	0.1	-3.0	-3.3	1.3	-3.3	-0.3	3.0	-2.4	1.1	-1.3	-1.7	-0.6	0.1	-0.3	-2.7
Number of self-reported non-cancer illnesses	0.8	1.3	4.5	1.1	1.8	1.4	1.0	1.5	1.2	-0.2	0.7	0.9	1.2	1.2	1.1	0.8	0.5	2.1
Medication: Atorvastatin	0.8	1.0	2.9	1.2	0.7	0.2	0.4	0.3	1.4	0.7	1.7	1.3	1.0	-0.1	1.1	1.3	1.5	0.8
Number of operations (self-reported)	0.8	1.2	2.4	-1.4	-0.5	-0.1	-1.4	0.2	-1.2	-1.4	-1.3	-1.6	-1.2	0.1	-1.2	-1.5	-1.5	-0.8
Pack years of smoking	0.8	1.1	3.3	1.2	-0.1	-0.8	1.8	-0.7	1.5	1.0	1.0	1.5	0.8	1.1	0.9	1.3	0.5	1.0
Rheumatoid Arthritis	0.7	1.0	3.3	-1.1	-1.2	-0.7	-0.8	-0.9	-0.9	0.4	-0.5	-0.8	-1.3	-1.4	-1.2	-1.1	0.4	-1.8
Type 2 Diabetes (T2D) (2012)	0.7	0.8	3.6	-0.2	0.8	1.8	0.4	1.9	-0.5	0.7	-0.6	-0.6	0.3	1.6	0.0	-0.3	-0.2	0.5
Neuroticism	0.7	1.6	4.7	-0.9	-1.2	-2.0	-1.3	-2.2	-0.3	0.2	-0.5	-0.8	-1.6	-2.0	-1.2	-0.7	1.1	-1.8
Hearing difficulty/problems: Yes	0.7	1.1	5.0	-0.3	1.6	2.2	0.1	2.1	-0.3	-0.7	0.3	-0.6	0.5	0.9	0.0	-0.5	-0.8	1.8
Ever had hysterectomy (womb removed)	0.7	0.8	3.5	1.1	0.1	-0.4	0.7	-0.2	0.9	1.9	0.6	1.2	0.8	-0.2	0.9	1.1	1.5	-0.4
Medication for hormone replacement therapy	0.7	0.8	1.7	1.0	1.0	0.7	0.5	0.8	1.1	0.1	1.3	0.7	1.3	0.5	1.1	1.2	0.9	0.4
Vitamin and mineral supplements	0.7	0.9	2.5	0.9	0.8	1.1	1.2	1.2	0.7	1.6	0.4	0.7	1.1	0.7	1.1	0.8	0.4	1.3
High blood pressure (mother)	0.7	1.0	2.3	-1.4	-0.6	0.1	-1.1	0.3	-1.1	-1.5	-1.1	-1.5	-1.2	-0.7	-1.3	-1.4	-0.6	-0.1
Trunk fat mass	0.7	3.0	12.1	1.1	-2.1	-3.5	1.7	-2.8	1.6	2.0	0.6	1.7	-0.3	-0.6	0.5	1.3	1.9	-1.9
Number of incorrect matches in round	0.7	1.2	2.9	1.3	0.2	-1.2	0.9	-0.9	1.4	-0.7	1.7	1.4	0.8	-0.8	0.9	1.3	1.5	0.4
Frequency of tenseness / restlessness in last 2 weeks	0.7	1.0	4.8	-0.7	-1.0	-1.8	-1.4	-2.2	-0.4	-0.4	-0.8	-0.5	-1.2	-0.8	-1.0	-0.6	0.2	-0.8
Hayfever/allergic rhinitis (self-reported)	0.7	1.0	2.1	1.3	0.8	0.2	1.1	0.0	1.4	1.2	0.7	1.5	0.9	1.4	1.1	1.0	0.9	0.8
Trunk fat-free mass	0.7	3.9	14.1	0.6	-2.5	-3.1	2.0	-3.2	0.0	3.8	-2.4	1.6	-0.8	-1.8	-0.2	0.4	-0.3	-2.2
Trunk predicted mass	0.7	3.8	13.8	0.6	-2.5	-3.1	2.0	-3.2	0.1	3.7	-2.4	1.7	-0.8	-1.7	-0.1	0.4	-0.4	-2.1
Breastfed as a baby	0.7	0.8	2.4	-1.1	0.3	1.3	-1.5	1.2	-1.0	-0.8	-0.3	-1.6	-0.4	-0.5	-0.8	-1.1	-0.2	0.4
Medication: Ventolin 100micrograms inhaler	0.7	0.8	2.0	-1.1	-0.3	1.1	-0.8	0.7	-1.1	-1.0	-0.8	-1.4	-0.5	0.2	-0.9	-1.3	-1.3	0.4
Arm fat-free mass (right)	0.7	3.8	11.0	0.1	-3.0	-3.3	1.3	-3.2	-0.3	3.0	-2.5	1.1	-1.3	-1.6	-0.6	0.0	-0.5	-2.6
Eye problems/disorders: None of the above	0.7	0.8	2.2	-0.6	-1.5	-1.1	0.1	-1.1	-0.8	-0.2	-1.1	-0.0	-0.9	-0.8	-0.7	-0.8	-1.4	-1.0
Age at last live birth	0.7	1.1	2.4	0.8	1.6	1.2	0.5	1.0	1.0	1.0	1.3	0.6	1.2	0.8	1.1	1.0	1.2	1.0
Supplements: Vitamin C	0.7	0.8	1.9	-1.1	-0.1	-0.4	-0.8	-0.4	-1.1	-1.3	-0.8	-1.0	-0.9	-1.4	-1.1	-1.0	-0.2	-0.8
Long-standing illness, disability or infirmity	0.7	1.1	2.4	1.4	1.5	0.6	0.5	0.7	1.0	0.2	0.7	1.5	1.2	1.0	1.3	1.3	0.7	1.4
Mouth/teeth dental problems: Mouth ulcers	0.7	1.2	5.3	-1.0	-1.0	0.0	-1.3	0.4	-1.2	-0.9	-1.6	-1.1	-0.7	0.3	-0.9	-1.4	-2.3	-0.4
Back pain experienced in last month	0.7	1.0	3.1	-0.5	-1.5	-1.8	-0.3	-1.6	-0.0	0.3	-0.7	-0.2	-0.9	-1.3	-0.8	-0.5	0.8	-1.6
Whole body water mass	0.7	3.8	9.9	-0.2	-2.9	-3.1	1.1	-3.1	-0.6	3.0	-2.8	0.8	-1.4	-1.8	-0.8	-0.3	-0.7	-2.7
Medication: Paracetamol	0.7	1.1	2.8	0.9	-0.9	-1.7	0.9	-1.5	1.1	0.8	1.1	1.4	0.0	-0.8	0.5	1.0	1.4	-1.0
Illnesses of father: High blood pressure	0.7	0.9	2.4	-1.2	-0.4	0.0	-1.6	-0.2	-1.1	-0.7	-1.4	-1.5	-0.9	-1.1	-1.0	-1.2	-0.2	-0.2
Risk taking	0.7	1.1	3.1	1.2	-0.4	-1.3	0.7	-1.3	1.0	1.4	0.8	1.8	0.5	-0.5	0.9	1.4	1.3	-0.3
Ever had prostate specific antigen (PSA) test	0.7	0.8	2.8	-0.3	0.2	0.9	-0.5	1.4	-1.1	-1.7	-1.4	-0.2	-0.1	1.1	-0.0	-0.8	-1.4	0.4
Type 2 Diabetes (T2D) (2018)	0.6	1.1	2.9	1.2	0.4	0.0	0.8	0.5	1.5	0.7	1.7	1.2	1.1	0.9	1.2	1.4	1.4	1.2
Number of treatments/medications taken	0.6	1.2	4.8	-0.4	-1.3	-2.2	-0.2	-1.8	0.3	-1.5	0.6	-0.1	-1.0	-1.4	-0.8	-0.1	0.7	-1.3
Leg fat-free mass (left)	0.6	3.0	7.2	-0.6	-2.7	-2.6	0.4	-2.5	-0.7	2.6	-2.5	-0.0	-1.6	-1.6	-1.1	-0.6	-0.3	-2.7
Medication: Atenolol	0.6	0.7	5.3	0.4	0.0	-0.4	0.8	-0.2	0.8	1.2	0.2	0.5	0.2	-1.5	0.4	0.6	2.3	-0.7
Nervous feelings	0.6	1.2	3.3	-0.9	1.6	1.8	-1.3	1.6	-0.8	-0.6	-1.2	-1.6	-0.0	0.1	-0.5	-1.1	-0.2	1.2
Weight	0.6	2.9	11.4	0.4	-2.5	-3.4	1.6	-3.0	0.6	2.4	-0.8	1.2	-1.0	-1.2	-0.3	0.5	0.6	-2.2
Asthma	0.6	1.2	4.3	0.1	1.5	2.1	-0.4	1.7	-0.3	-1.8	0.4	-0.1	0.7	1.1	0.3	-0.2	-1.6	1.2
Whole body fat mass	0.6	2.7	13.0	0.5	-2.5	-3.6	1.2	-3.0	1.0	1.5	0.1	1.1	-0.8	-0.9	-0.1	0.8	1.4	-2.1
Leg fat mass (right)	0.6	2.3	10.5	0.6	-2.3	-3.2	1.3	-2.7	1.0	1.4	0.4	1.1	-0.7	-0.7	0.0	0.9	1.3	-2.0
Illness, injury, bereavement, stress in last 2 years	0.6	0.8	2.3	-1.0	-0.0	0.8	-0.7	0.6	-1.4	0.1	-1.3	-1.1	-0.6	-0.1	-0.8	-1.3	-1.5	-0.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.6	0.7	2.3	1.1	0.5	0.1	1.3	0.2	1.1	0.3	1.5	1.3	0.9	0.1	1.0	1.1	0.5	0.2
Forced expiratory volume in 1-second (FEV1), predicted	0.6	1.3	5.8	0.1	-1.4	-2.3	0.3	-2.4	0.1	1.4	-0.6	0.8	-0.8	-0.8	-0.4	0.2	0.2	-1.8
Whole body fat-free mass	0.6	3.5	10.5	0.1	-2.7	-3.0	1.3	-3.0	-0.3	3.2	-2.6	1.0	-1.2	-1.7	-0.6	-0.0	-0.4	-2.5
Leg fat-free mass (right)	0.6	3.3	8.4	-0.9	-2.7	-2.6	0.2	-2.6	-1.1	2.1	-2.7	-0.3	-1.8	-1.6	-1.3	-0.9	-0.8	-2.9
Leg predicted mass (right)	0.6	3.2	8.1	-0.8	-2.7	-2.6	0.3	-2.5	-1.0	2.1	-2.7	-0.2	-1.8	-1.6	-1.3	-0.8	-0.8	-2.8
Basal metabolic rate	0.6	3.5	10.2	0.2	-2.7	-3.2	1.5	-3.1	-0.1	3.2	-2.1	1.1	-1.1	-1.6	-0.5	0.2	-0.2	-2.5
Arm fat-free mass (left)	0.6	3.1	9.8	0.4	-2.5	-3.1	1.5	-3.0	-0.0	2.7	-2.1	1.4	-0.9	-1.5	-0.3	0.3	-0.5	-2.2
Leg fat mass (left)	0.6	2.3	11.6	0.3	-2.5	-3.4	1.1	-2.8	0.8	1.0	0.1	0.9	-1.0	-0.7	-0.2	0.7	0.9	-2.3
Arm predicted mass (left)	0.6	3.1	9.5	0.5	-2.5	-3.1	1.6	-3.0	-0.0	2.9	-2.1	1.4	-0.9	-1.4	-0.3	0.3	-0.4	-2.2
Allergy or Eczema	0.5	1.3	4.2	1.0	1.8	2.1	0.8	1.7	0.8	0.8	1.1	0.8	1.3	0.4	1.1	0.6	0.8	1.1
Frequency of depressed mood in last 2 weeks	0.5	0.7	1.8	-0.9	-1.1	-1.0	-1.2	-1.0	-0.5	-1.4	-0.4	-0.8	-1.0	0.1	-1.0	-0.7	-0.8	-0.5
Ever used hormone-replacement therapy (HRT)	0.5	0.7	1.5	1.1	0.7	0.8	0.8	1.2	0.7	0.3	0.2	1.0	1.2	0.8	1.1	0.8	0.4	0.7
Trunk fat percentage	0.5	1.9	7.7	0.9	-1.5	-2.8	1.1	-2.0	1.6	1.0	1.1	1.3	-0.1	-0.1	0.5	1.2	2.1	-1.3
Fed-up feelings	0.5	0.9	2.4	-0.9	-0.9	-1.5	-0.7	-1.6	-0.2	0.5	-0.1	-0.9	-1.3	-1.1	-1.1	-0.6	1.0	-0.5
High blood pressure	0.5	1.3	3.3	1.1	1.4	1.0	0.5	1.1	1.4	-0.4	1.6	0.9	1.2	-0.0	1.1	1.2	1.8	1.5
Leg predicted mass (left)	0.5	2.9	6.9	-0.5	-2.6	-2.6	0.5	-2.5	-0.7	2.6	-2.4	0.1	-1.5	-1.6	-1.0	-0.5	-0.2	-2.6
Medication: Lansoprazole	0.5	0.6	2.6	-0.2	-0.6	-1.3	0.1	-1.3	0.1	-0.1	0.4	0.3	-0.5	-1.6	-0.3	0.1	0.6	-1.3
Illnesses of mother	0.5	0.6	2.0	-0.6	-0.9	-0.5	0.3	-0.7	-1.1	0.5	-1.4	-0.4	-0.8	-0.2	-0.8	-0.8	-1.4	-0.6
Arm fat mass (right)	0.5	2.1	9.4	-0.6	-2.5	-3.1	0.3	-2.6	-0.2	0.7	-0.7	-0.1	-1.6	-1.1	-1.0	-0.3	0.2	-2.3
Number of children fathered	0.5	0.6	2.0	0.4	0.5	1.4	0.3	1.4	0.2	0.5	-0.4	0.2	0.8	1.4	0.7	0.2	-0.2	1.0
Mouth/teeth dental problems: Loose teeth	0.5	0.5	1.8	-0.1	-0.4	-1.1	-0.4	-1.1	-0.6	-0.5	-1.1	0.3	-0.7	-1.1	-0.4	-0.4	0.2	-1.3
Medication: Ibuprofen	0.5	0.5	1.7	-0.8	-1.1	-0.7	-0.6	-0.4	-0.4	-1.3	-0.3	-0.9	-0.8	0.2	-0.8	-0.8	-0.2	-0.9
Alcohol intake frequency.	0.5	1.2	2.4	-1.3	-0.8	-1.1	-1.5	-1.1	-1.1	-1.5	-0.7	-1.4	-1.4	-0.4	-1.3	-1.1	-0.8	-0.6
Qualifications: nursing, teaching	0.5	0.8	2.0	-0.9	-0.2	0.4	-1.4	0.4	-1.1	-1.1	-1.2	-1.0	-0.6	-0.2	-0.7	-0.9	-1.3	-1.0
Asthma (self-reported)	0.5	0.9	3.3	0.4	1.5	1.8	0.1	1.5	0.0	-1.3	0.7	0.3	0.8	1.0	0.5	0.2	-1.1	1.2
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.5	1.0	2.6	-0.9	0.3	1.3	-0.9	1.6	-1.0	-0.8	-1.3	-1.3	-0.1	0.7	-0.4	-1.1	-1.3	0.9
Average weekly beer plus cider intake	0.5	0.7	2.4	0.9	0.7	0.3	0.6	0.6	1.0	-0.6	1.2	1.0	0.9	1.5	0.9	0.9	-0.5	0.2
Cholesterol lowering medication	0.5	0.8	3.0	1.1	-0.1	-0.7	0.6	-0.3	1.3	-0.0	1.1	1.2	0.7	-0.7	0.9	1.1	1.7	-0.1
Neuroticism (Nagel 2018)	0.4	0.9	2.9	-0.4	-0.5	-1.5	-0.7	-1.7	0.0	0.8	-0.3	-0.3	-1.1	-1.2	-0.7	-0.2	1.6	-1.3
Crohns Disease (2017)	0.4	0.9	3.6	1.0	0.6	1.2	1.5	1.4	0.3	1.9	-0.4	0.9	1.3	-0.2	0.9	0.3	-0.4	0.4
Ulcerative Colitis (UC)	0.4	0.8	4.3	-0.6	-0.7	-0.8	-0.5	-0.7	-0.2	-1.0	0.4	-0.5	-0.7	-2.1	-0.6	-0.7	-0.5	-1.6
Coronary Artery Disease (CAD)	0.4	0.5	1.3	0.9	-0.8	-0.9	1.0	-1.0	0.5	0.9	0.4	1.1	-0.0	-0.3	0.3	0.6	0.0	-0.1
Primary Biliary Cirrhosis	0.4	0.6	1.6	1.0	-0.3	-1.0	0.6	-0.4	1.2	0.4	0.6	0.8	0.8	-0.4	0.8	1.1	1.2	0.1
Blood Platelet Count	0.4	5.0	14.5	2.8	0.6	-1.0	2.1	-0.3	3.5	1.9	3.8	2.8	2.3	1.2	2.4	3.0	2.4	0.7
Eye problems/disorders: Diabetes related eye disease	0.4	0.5	1.7	0.7	1.0	0.3	0.6	0.3	0.6	-0.1	1.3	0.6	0.6	0.4	0.7	0.9	0.8	0.6
Townsend deprivation index at recruitment	0.4	0.5	2.6	0.2	0.9	1.0	0.6	1.0	0.2	-0.4	0.4	0.1	0.4	1.6	0.2	0.0	-0.6	1.2
Sitting height	0.4	3.1	13.3	2.3	1.2	0.3	1.3	-0.3	0.8	3.6	-2.2	2.9	1.7	1.5	2.0	1.7	0.7	1.1
Had menopause	0.4	0.5	1.7	0.9	0.4	-0.1	0.9	0.2	0.9	0.7	0.8	1.0	0.7	-0.3	0.7	0.9	1.3	0.2
Ever unenthusiastic/disinterested for a whole week	0.4	0.5	2.5	0.7	1.0	0.2	0.8	0.5	0.6	-0.1	-0.4	0.5	1.0	0.9	0.8	0.6	-0.1	1.6
Pain all over the body in last month	0.4	0.4	1.6	-0.4	-0.8	-1.1	-0.5	-1.3	-0.2	-0.4	0.1	-0.1	-0.7	-1.2	-0.6	-0.2	0.0	-0.3
Father’s age at death	0.4	0.5	1.5	-1.1	-0.2	0.3	-0.9	0.1	-1.1	-0.2	-1.2	-1.1	-0.7	-0.4	-0.9	-1.0	-0.3	-0.3
Length of working week for main job	0.4	0.4	1.8	0.7	0.4	-0.3	0.5	-0.1	0.8	-0.0	1.3	0.7	0.4	0.6	0.5	1.0	0.6	0.3
Peak expiratory flow (PEF)	0.4	0.9	4.3	-0.9	-0.3	0.4	-1.3	-0.2	-1.2	1.5	-2.1	-1.1	-0.6	-0.7	-0.8	-0.7	0.2	0.4
Pulse wave reflection index	0.4	0.5	1.4	-0.6	-1.2	-0.7	-0.6	-0.6	-0.6	-0.9	-0.8	-0.4	-0.6	-0.8	-0.4	-0.5	-0.8	-0.9
Headache pain in last month	0.4	0.7	3.0	0.3	-0.9	-1.7	-0.3	-1.4	0.5	-0.1	1.0	0.6	-0.4	-0.4	-0.0	0.6	1.2	-1.2
Body fat percentage	0.4	1.7	7.6	0.7	-1.7	-2.8	1.0	-2.0	1.3	0.8	1.0	1.0	-0.4	-0.1	0.3	1.0	1.7	-1.6
Leg fat percentage (right)	0.4	1.3	5.8	0.7	-1.6	-2.4	1.2	-1.7	1.2	0.6	1.1	1.0	-0.3	0.1	0.3	0.9	1.3	-1.2
Mean time to correctly identify matches	0.4	0.8	3.1	1.1	0.8	0.6	0.7	0.8	0.6	-1.1	0.5	1.0	1.2	0.4	1.2	1.0	-0.0	1.8
Illnesses of siblings: Diabetes	0.4	0.4	2.5	-0.7	-0.3	0.2	-0.6	0.1	-0.2	-1.6	0.4	-0.9	-0.5	0.1	-0.6	-0.7	-0.7	1.0
Arm fat percentage (left)	0.4	1.5	5.5	-0.9	-2.1	-2.4	-0.2	-1.8	-0.2	-0.2	-0.2	-0.7	-1.5	-0.5	-1.1	-0.6	0.5	-2.0
Handedness (chirality/laterality): Left-handed	0.4	0.5	1.6	0.6	0.9	0.3	0.4	0.3	0.8	-0.6	1.2	0.7	0.7	0.1	0.6	0.7	0.1	1.3
Ever had bowel cancer screening	0.4	0.5	3.1	0.7	0.3	0.1	0.9	0.4	0.6	0.7	0.4	0.6	0.6	-1.8	0.5	0.4	1.0	-0.2
Diabetes diagnosed by doctor	0.4	0.6	2.0	0.7	0.3	-0.4	0.2	-0.3	1.0	1.0	0.9	0.9	0.5	0.0	0.7	0.9	1.4	1.0
Osteoarthritis (self-reported)	0.4	0.5	3.2	-0.5	0.4	0.1	-0.7	0.1	-0.9	-1.8	-0.6	-0.6	-0.4	0.2	-0.5	-0.5	-1.1	0.1
Medication: Aspirin	0.4	0.5	2.3	0.3	-0.9	-1.5	0.1	-1.1	0.7	-0.3	0.4	0.4	-0.2	-1.0	0.1	0.3	1.2	-0.6
Arm fat mass (left)	0.4	1.8	8.4	-0.4	-2.4	-2.9	0.5	-2.4	0.0	0.9	-0.6	0.1	-1.4	-0.8	-0.8	-0.1	0.4	-2.2
Medication: Blood pressure	0.4	0.7	3.5	0.7	0.6	-0.2	0.7	0.1	1.0	-0.6	1.0	0.5	0.8	-1.3	0.6	0.9	1.9	0.5
Leg fat percentage (left)	0.4	1.4	7.5	0.4	-1.9	-2.7	1.0	-1.9	0.9	-0.0	0.8	0.8	-0.6	0.0	-0.0	0.7	0.9	-1.5
Commuting to job workplace: Cycle	0.4	0.5	2.2	-0.3	-0.7	-0.9	-0.6	-0.9	-0.5	-1.2	0.1	-0.0	-0.6	-0.8	-0.5	-0.1	-0.5	-1.5
Vascular/heart problems diagnosed by doctor	0.4	1.1	4.3	-1.1	-1.1	-0.6	-0.4	-0.7	-1.5	0.1	-1.4	-1.0	-1.1	0.3	-1.1	-1.2	-2.1	-1.2
Basal cell carcinoma (self-reported)	0.4	0.4	2.8	0.2	0.7	1.1	0.6	0.7	0.0	-0.2	0.3	0.0	0.4	1.7	0.2	0.2	-1.0	0.3
Heart attack/myocardial infarction (self-reported)	0.4	0.5	2.2	-0.3	-0.5	-1.1	-1.5	-1.0	-0.2	-0.6	-0.5	-0.3	-0.5	-1.1	-0.4	-0.4	0.2	-0.8
Alcohol drinker status: Previous	0.4	0.5	2.2	0.1	1.0	0.4	-0.8	0.3	0.2	-1.5	0.3	-0.2	0.2	1.0	0.1	-0.0	-0.7	1.5
Major Depression (MDD)	0.3	0.4	1.6	0.0	1.2	1.3	-0.1	1.1	-0.0	-0.3	0.2	-0.3	0.5	0.4	0.4	-0.1	0.0	1.1
Breast Cancer	0.3	0.6	1.7	1.0	0.4	-0.1	0.9	-0.2	0.9	-0.4	1.3	1.3	0.6	1.2	0.8	1.0	-0.1	0.2
Age at First Birth	0.3	0.5	2.0	0.2	0.7	1.3	0.0	1.4	-0.5	-0.6	-0.7	0.1	0.5	0.7	0.5	0.0	-1.1	0.4
HbA1C	0.3	0.3	1.4	0.4	0.3	1.1	0.3	1.2	0.2	-0.2	0.5	0.1	0.8	0.6	0.8	0.4	0.1	0.6
Neuroticism (2016)	0.3	0.5	2.4	-0.3	-0.7	-1.5	-0.6	-1.3	0.1	-0.1	-0.3	-0.5	-0.6	-1.3	-0.4	-0.3	0.3	-0.6
Smoking Status	0.3	0.7	3.0	-0.3	-1.4	-1.7	-0.6	-1.7	-0.2	0.2	-0.2	0.1	-0.8	-1.1	-0.4	0.1	0.1	-1.1
Cardiovascular Disease	0.3	0.9	3.6	1.0	0.1	-0.6	0.3	-0.7	1.4	-0.0	1.6	1.1	0.5	-0.5	0.7	1.3	1.9	-0.2
Hair Pigment	0.3	7.2	13.9	-3.3	-1.2	-1.0	-3.7	-1.4	-3.5	-3.2	-3.5	-3.4	-3.2	-0.3	-3.1	-2.9	-2.3	-2.3
Tanning	0.3	3.9	12.7	-1.2	-3.0	-3.6	-0.3	-3.1	-0.5	-1.3	-0.7	-0.6	-1.8	-3.0	-1.5	-0.9	-0.9	-3.3
Relative age of first facial hair	0.3	0.5	1.9	0.7	0.7	0.8	0.2	0.6	0.6	-0.0	0.8	0.6	0.7	1.4	0.8	0.8	0.8	0.8
Medication: Metformin	0.3	0.5	0.9	-0.9	-0.9	-0.6	-0.8	-0.6	-0.8	-0.1	-0.7	-0.6	-0.9	-0.6	-0.9	-0.8	-0.2	-0.5
Maternal smoking around birth	0.3	0.4	1.2	0.8	-0.4	-0.9	0.8	-0.6	0.8	0.2	0.5	1.1	0.4	-0.1	0.6	0.8	0.3	-0.4
Bilateral oophorectomy (both ovaries removed)	0.3	0.3	1.4	-0.4	0.9	1.1	-1.2	0.7	-0.3	-0.3	0.1	-0.7	-0.0	0.4	-0.1	-0.1	0.6	0.3
Supplements: Glucosamine	0.3	0.4	2.2	0.7	0.1	-0.2	1.5	-0.2	0.7	0.7	0.4	1.0	0.4	0.6	0.5	0.7	0.3	-0.6
Heart attack	0.3	0.4	2.1	-0.3	-0.4	-0.8	-1.5	-0.8	-0.2	-0.7	-0.5	-0.3	-0.5	-1.0	-0.4	-0.5	0.2	-0.7
Diabetes (self-reported)	0.3	0.5	1.7	0.6	0.4	-0.3	0.3	-0.1	0.8	1.0	0.8	0.7	0.6	-0.5	0.6	0.7	1.1	1.3
Arm fat percentage (right)	0.3	1.2	4.5	-0.9	-1.8	-2.1	-0.3	-1.7	-0.3	-0.5	-0.2	-0.7	-1.4	-0.4	-1.0	-0.6	0.2	-1.8
Hip circumference	0.3	1.2	3.9	-0.5	-1.7	-2.0	0.3	-1.7	-0.4	1.1	-1.3	-0.1	-1.3	-0.4	-0.8	-0.5	-0.3	-1.7
Worrier / anxious feelings	0.3	0.5	1.5	0.6	1.0	0.4	0.4	0.6	0.9	1.1	0.1	0.3	0.8	-0.3	0.8	0.4	1.2	0.7
Pulse wave Arterial Stiffness index	0.3	0.4	2.2	0.3	-0.8	-1.5	-0.2	-1.2	0.6	-0.2	-0.2	0.6	0.1	-0.5	0.4	0.5	0.2	0.2
Seen doctor (GP) for nerves, anxiety, tension or depression	0.3	0.4	1.1	0.7	0.8	0.4	0.5	0.8	0.6	-0.0	0.1	0.6	0.9	1.1	0.8	0.6	-0.0	1.0
Gout (self-reported)	0.3	0.5	1.5	-1.1	-0.4	0.6	-1.0	0.6	-0.7	-0.4	-0.2	-1.2	-0.6	0.1	-0.8	-0.9	-0.7	-0.2
Birth weight	0.3	0.7	2.9	1.0	0.2	-0.3	1.5	0.0	0.7	0.0	0.7	1.7	0.6	1.1	0.7	0.7	-1.2	0.2
Reason for reducing amount of alcohol drunk: Health precaution	0.3	0.4	1.9	0.4	0.9	0.7	0.1	0.5	0.4	0.4	0.9	0.4	0.4	0.3	0.4	0.6	1.4	-0.5
Pulse wave peak to peak time	0.3	0.3	1.3	0.3	0.8	1.1	0.8	1.0	-0.0	0.7	0.7	0.1	0.3	0.4	0.1	0.1	0.1	-0.1
Migraine (self-reported)	0.3	0.3	1.1	-0.5	-0.4	-0.7	-0.9	-1.0	-0.5	-0.1	-0.1	-0.5	-0.6	-0.5	-0.5	-0.2	0.2	-1.0
Chest pain or discomfort	0.3	0.5	1.8	0.2	1.0	1.3	0.4	1.2	0.7	0.7	0.7	-0.1	0.5	0.2	0.3	-0.2	0.3	1.0
Had major operations	0.3	0.4	1.5	0.4	-0.3	-0.4	0.7	-0.4	0.9	1.2	0.8	0.6	-0.0	0.7	0.3	0.5	1.0	-0.2
Commuting to job workplace: Car/motor vehicle	0.3	0.3	1.0	-0.4	0.6	0.9	-0.3	0.8	-0.2	-0.3	-0.1	-0.5	0.0	1.0	-0.1	-0.4	-0.8	1.0
Medication: Aspirin	0.3	0.4	2.1	0.6	-0.4	-0.9	0.5	-0.5	1.0	-0.0	0.8	0.6	0.3	-0.3	0.5	0.7	1.5	-0.3
Eye problems/disorders: Cataract	0.3	0.4	1.2	0.1	1.0	0.9	-0.7	0.9	0.1	-1.1	0.7	-0.2	0.3	0.7	0.3	0.3	0.7	0.2
Breast cancer (self-reported)	0.3	0.4	1.2	-0.2	0.4	1.0	-0.0	0.9	0.1	1.0	0.3	-0.7	0.2	-0.5	0.1	-0.0	1.1	0.7
Hearing aid user	0.3	0.3	1.5	-0.2	-0.3	-0.5	0.3	-0.9	-0.1	0.9	0.4	0.0	-0.7	-0.3	-0.5	-0.1	0.5	-1.2
Mother’s age at death	0.3	0.4	1.0	0.8	1.0	0.5	-0.4	0.5	0.5	0.3	0.3	0.8	0.9	-0.2	0.8	0.7	0.8	0.7
Ever smoked	0.3	0.4	1.6	-0.5	-0.2	-0.4	-0.8	-0.3	-0.8	-1.2	-0.7	-0.5	-0.7	-0.5	-0.6	-0.4	-0.4	-1.3
Ever depressed for a whole week	0.3	0.3	1.9	0.1	-0.7	-1.4	0.9	-1.0	0.4	-0.4	-0.4	0.2	-0.1	-0.7	-0.0	0.1	-0.2	-0.3
Depression (Nagel 2018)	0.2	0.4	1.0	0.6	-0.1	-0.7	0.3	-0.6	0.9	-0.1	0.8	0.7	0.3	0.8	0.5	1.0	0.8	0.1
LDL Cholesterol	0.2	0.4	1.1	-0.3	1.0	1.1	-0.2	1.0	-0.1	-1.0	0.6	-0.4	0.3	0.6	-0.0	0.0	-0.5	0.5
Ulcerative Colitis	0.2	0.3	1.2	-0.5	-0.6	-0.7	-0.2	-0.7	-0.2	-0.6	0.1	-0.0	-0.7	-0.7	-0.5	-0.6	0.0	-1.1
Respiratory disease	0.2	0.4	1.5	0.1	0.9	1.2	0.0	0.9	-0.1	-1.1	0.3	-0.0	0.4	0.5	0.1	-0.1	-0.9	0.8
Sensitivity / hurt feelings	0.2	0.3	1.2	0.4	-0.4	-1.1	0.5	-0.9	0.8	0.9	0.3	0.5	-0.1	-0.3	0.1	0.5	0.5	-0.3
Relative age voice broke	0.2	0.4	1.7	-0.7	-0.4	0.2	-0.1	-0.0	-0.9	-0.3	-0.3	-0.7	-0.7	0.5	-0.7	-0.7	-0.5	-1.3
Past tobacco smoking	0.2	0.4	1.5	-0.1	-1.2	-1.2	0.4	-1.2	0.5	0.8	0.2	0.1	-0.3	-0.4	-0.2	-0.0	0.4	0.2
Hair/balding pattern: Pattern 2	0.2	0.2	1.0	0.2	0.2	0.1	-0.2	0.1	-0.2	0.3	-0.9	0.3	0.0	0.9	0.3	0.1	0.1	-1.0
Qualifications: None of the above	0.2	0.5	2.9	0.6	0.1	-0.4	0.9	-0.0	1.2	-0.3	1.7	0.5	0.4	0.1	0.5	0.8	1.1	0.4
Medication: Simvastatin	0.2	0.3	1.7	0.5	-0.1	-0.5	0.6	-0.0	0.8	0.1	0.2	0.5	0.3	-0.5	0.5	0.4	1.3	-0.7
Forced expiratory volume in 1-second (FEV1)	0.2	0.7	5.7	0.6	0.4	0.5	0.5	0.3	0.3	2.4	-0.5	0.5	0.6	0.1	0.6	0.7	1.0	0.7
Medication: Cholesterol lowering	0.2	0.2	1.2	-0.4	0.1	0.3	-1.1	0.5	-0.1	-0.9	-0.2	-0.6	-0.3	-0.2	-0.2	-0.4	0.7	-0.3
Exposure to tobacco smoke outside home	0.2	0.2	1.0	0.3	-0.2	-1.0	0.3	-1.0	0.3	-0.2	-0.4	0.7	-0.3	0.3	-0.0	0.2	-0.3	-0.1
Number of full brothers	0.2	0.2	1.7	0.3	-0.0	0.4	0.7	0.6	0.5	-0.0	1.3	0.2	0.4	-0.1	0.3	0.3	-0.1	-0.2
Wheeze or whistling in the chest in last year	0.2	0.4	2.2	-0.2	-0.9	-1.0	0.5	-1.0	-0.0	-0.6	0.1	0.1	-0.7	-1.5	-0.7	-0.4	-0.4	-0.3
Heart disease (mother)	0.2	0.2	0.6	0.3	0.3	-0.5	0.4	-0.3	0.5	-0.2	0.8	0.3	0.1	-0.8	0.2	0.3	0.7	0.1
Hypertension (Self-reported)	0.2	0.7	2.4	0.7	1.0	0.9	0.1	1.0	1.0	-0.4	1.1	0.5	0.8	-0.2	0.7	0.7	1.6	1.1
Commuting to job workplace: Walk	0.2	0.2	0.9	-0.2	-0.5	-0.6	-0.1	-0.7	-0.5	0.2	-0.7	-0.0	-0.4	-0.9	-0.4	-0.3	0.0	-0.8
Miserableness	0.2	0.4	1.4	-0.2	-0.5	-1.0	-0.4	-1.1	0.3	1.1	-0.1	-0.2	-0.6	-0.7	-0.4	-0.0	1.2	-0.6
Unable to work because of sickness or disability	0.2	0.2	0.7	0.5	-0.1	-0.0	0.6	-0.2	0.6	-0.3	0.7	0.7	0.2	0.5	0.5	0.8	0.6	0.1
Supplements: Calcium	0.2	0.2	0.9	-0.5	0.1	0.8	-0.4	0.4	-0.2	0.0	-0.4	-0.7	0.0	0.0	-0.2	-0.6	0.0	1.0
Worry (Nagel 2018)	0.1	0.2	0.7	-0.4	0.8	0.1	-0.8	0.0	-0.1	0.2	-0.7	-0.7	-0.4	-0.3	-0.4	-0.5	0.8	0.2
Alzheimer’s Disease (including proxy)	0.1	0.2	0.6	0.1	0.8	0.6	-0.5	0.6	0.4	-0.4	0.8	0.0	0.3	0.7	0.2	0.2	-0.1	0.5
Irritable Bowel Disease (IBD)	0.1	0.4	3.3	0.3	-0.0	0.2	0.7	0.5	0.2	0.6	0.2	0.3	0.4	-1.8	0.2	-0.2	-0.5	-0.7
Lupus	0.1	0.2	1.3	-0.1	-0.0	-0.7	-0.3	-0.3	-0.1	-0.9	-0.2	-0.0	-0.4	-0.3	-0.4	-0.2	-1.1	-0.4
Triglycerides	0.1	0.1	0.5	-0.0	-0.3	0.6	-0.1	0.5	-0.5	0.1	-0.7	0.2	-0.2	-0.0	-0.1	-0.1	-0.6	0.0
Systolic blood pressure, automated reading	0.1	0.2	0.9	0.0	0.4	0.8	0.0	0.6	-0.2	0.5	-0.1	-0.1	0.2	-0.3	0.2	0.1	0.9	0.4
Angina	0.1	0.2	1.1	0.2	0.2	0.3	-0.4	0.0	0.3	1.0	0.0	0.3	-0.0	0.0	0.3	0.1	1.0	-0.1
Diabetes (father)	0.1	0.2	1.1	-0.2	0.3	-0.2	0.2	-0.1	0.3	0.8	0.0	-0.5	0.0	-0.6	-0.1	0.0	1.0	-0.3
Average weekly fortified wine intake	0.1	0.1	0.3	0.2	-0.2	-0.2	-0.0	-0.3	-0.1	0.6	-0.5	0.2	0.1	-0.4	0.0	0.0	-0.5	0.2
Frequency of unenthusiasm / disinterest in last 2 weeks	0.1	0.1	0.3	-0.1	-0.0	-0.5	-0.2	-0.5	0.4	-0.3	0.2	-0.0	-0.2	0.6	-0.1	0.1	0.0	0.1
Taking other prescription medications	0.1	0.2	0.4	-0.3	-0.5	-0.7	0.0	-0.2	-0.1	-0.7	-0.6	-0.1	-0.4	0.1	-0.4	-0.4	-0.6	-0.1
Hayfever, allergic rhinitis or eczema	0.1	0.2	1.6	-0.1	0.7	1.3	-0.3	0.9	-0.2	0.1	0.2	-0.4	0.2	0.1	-0.0	-0.2	0.4	0.4
Diverticular disease/diverticulitis (self-reported)	0.1	0.2	1.1	-0.2	-0.0	-0.6	0.0	-0.3	-0.1	-1.0	0.1	-0.1	-0.2	-0.1	-0.3	-0.1	-0.6	0.5
Chronic bronchitis/emphysema (father)	0.1	0.2	0.7	0.4	0.7	0.4	0.3	0.2	0.3	-0.5	0.8	0.4	0.4	-0.1	0.3	0.3	0.3	0.4
Allergy	0.1	0.3	1.7	0.2	-0.8	-1.3	0.7	-1.0	0.4	0.4	0.0	0.5	-0.3	0.1	0.1	0.5	0.2	-0.7
Medication: Ramipril	0.1	0.2	0.7	0.4	-0.1	-0.3	0.6	-0.0	0.6	0.8	0.2	0.5	0.2	-0.1	0.4	0.3	0.8	0.2
Frequency of tiredness / lethargy in last 2 weeks	0.1	0.1	0.4	0.3	-0.1	-0.6	-0.2	-0.5	0.6	-0.1	0.5	0.5	-0.0	0.2	0.1	0.4	0.3	0.1
Noisy workplace	0.1	0.2	0.9	0.4	0.5	0.3	0.2	0.1	0.3	-0.3	0.5	0.5	0.3	0.9	0.4	0.6	0.3	-0.0
Mouth/teeth dental problems: Dentures	0.1	0.1	0.6	-0.2	-0.1	-0.4	0.4	-0.4	0.1	-0.1	-0.2	0.0	-0.4	0.6	-0.2	-0.3	-0.4	0.8
Medication: Ibuprofen (e.g. Nurofen)	0.1	0.1	0.5	0.1	-0.5	-0.4	0.1	0.1	0.3	-0.7	0.3	-0.1	-0.0	0.6	-0.1	-0.2	0.2	-0.2
Depression (self-reported)	0.1	0.1	0.3	0.3	-0.2	-0.2	0.3	-0.1	0.6	0.5	0.1	0.3	0.1	0.5	0.3	0.3	0.4	-0.2
Lung cancer (father)	0.1	0.1	1.1	0.1	0.1	-0.1	-0.1	0.0	-0.1	0.4	-0.0	-0.0	-0.2	-0.2	-0.1	0.1	1.1	-0.2
Forced expiratory volume in 1-second (FEV1), Best measure	0.1	0.2	1.6	0.3	-0.1	0.2	0.4	0.2	0.0	1.3	-0.5	0.2	0.3	0.4	0.4	0.4	0.0	0.6
Exposure to tobacco smoke at home	0.1	0.1	0.3	0.0	-0.1	-0.4	0.3	-0.5	0.2	0.3	0.0	0.3	-0.2	-0.3	-0.2	0.1	0.5	-0.4
Tense / ‘highly strung’	0.1	0.2	0.9	-0.2	0.2	-0.7	-0.4	-0.9	0.3	0.0	0.2	-0.3	-0.4	-0.5	-0.4	-0.1	0.9	-0.0
Loud music exposure frequency	0.1	0.1	0.3	-0.0	0.3	0.4	0.5	0.3	0.2	0.5	0.1	0.1	0.2	0.5	0.0	0.2	-0.2	0.4
Qualifications: O levels/GCSEs or equivalent	0.1	0.2	1.1	-0.2	0.2	0.4	-0.4	0.2	-0.5	0.7	-1.0	-0.2	-0.0	0.7	-0.1	-0.3	-0.8	0.7
Medication for cholesterol, blood pressure or diabetes	0.1	0.1	0.5	-0.0	-0.4	-0.7	0.4	-0.6	-0.2	0.3	-0.2	0.0	-0.0	0.4	-0.3	-0.0	-0.5	-0.2
Worry too long after embarrassment	0.1	0.2	0.7	-0.1	0.4	-0.1	-0.7	-0.3	0.1	0.7	-0.7	-0.2	-0.1	-0.5	0.0	-0.2	0.9	0.3
Angina (self-reported)	0.1	0.1	0.6	-0.2	-0.2	0.2	-0.7	-0.0	0.0	0.8	-0.2	-0.0	-0.3	-0.0	-0.0	-0.2	0.6	-0.3
Medication: Allopurinol	0.1	0.1	0.2	-0.5	-0.1	0.3	-0.4	0.2	-0.1	0.5	-0.0	-0.4	-0.4	-0.1	-0.3	-0.4	-0.2	-0.5
Illnesses of father: Heart disease	0.1	0.2	0.7	0.3	-0.1	-0.5	0.8	-0.4	0.5	0.5	-0.6	0.4	0.2	-0.3	0.3	0.3	0.1	0.1
Illnesses of father: None of the above (group 1)	0.1	0.1	0.4	-0.2	-0.5	-0.2	-0.2	-0.1	-0.4	-0.2	0.6	-0.2	-0.3	0.4	-0.2	-0.1	-0.4	-0.1
Wears glasses or contact lenses	0.1	0.1	0.9	0.2	0.4	0.2	-0.1	0.3	0.2	-0.4	-0.1	0.1	0.2	0.9	0.2	0.1	0.1	0.8
High cholesterol (Self-reported)	0.1	0.3	2.3	0.2	-0.0	-0.2	-0.5	-0.0	0.3	-1.5	0.6	0.1	-0.0	-0.5	0.2	0.2	0.8	-0.3
Alcohol drinker status: Never	0.1	0.1	0.6	-0.1	-0.4	-0.3	-0.6	-0.3	-0.1	0.8	-0.4	-0.3	-0.2	0.0	-0.2	-0.1	0.5	0.0
Age started oral contraceptive pill	0.1	0.1	0.6	-0.2	0.2	0.4	-0.0	0.5	-0.4	0.0	-0.1	-0.3	-0.1	-0.8	-0.2	-0.3	-0.2	0.4
Diastolic blood pressure, automated reading	0.1	0.2	1.0	0.1	0.5	0.1	-0.1	-0.1	0.0	0.6	-0.6	-0.2	0.1	0.2	0.2	0.3	1.0	0.6
Systolic Blood Pressure	0.0	0.1	0.3	0.1	0.2	0.4	-0.2	-0.2	-0.2	0.2	0.1	0.0	0.1	-0.6	0.0	0.4	0.6	0.2
Age when periods started (menarche)	0.0	0.1	0.7	0.2	0.3	0.4	0.0	0.5	0.1	-0.5	-0.3	0.1	0.4	0.1	0.2	-0.0	-0.8	-0.1

Hub : Genes

ATP6V0D1

Models

Trait associations