Best TWAS P=6.73e-09 · Best GWAS P=0.00637 conditioned to 0.0796
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Adipose Subcutaneous | KANSL1 | 0.35 | 0.09 | enet | 13 | 0.12 | 1.1e-09 | 3.2 | -5.5 | 3.2e-08 | 0.08 | 0 | 0.16 | FALSE |
2 | GTEx | Artery Aorta | KANSL1 | 0.42 | 0.08 | lasso | 4 | 0.14 | 2.4e-08 | 3.2 | -5.6 | 2.6e-08 | -0.13 | 0 | 0.01 | FALSE |
3 | GTEx | Breast Mammary Tissue | KANSL1 | 0.31 | 0.00 | enet | 9 | 0.11 | 2.6e-06 | 3.2 | -5.5 | 3.3e-08 | -0.18 | 0 | 0.00 | FALSE |
4 | GTEx | Esophagus Muscularis | KANSL1 | 0.41 | 0.11 | enet | 8 | 0.15 | 1.3e-09 | 3.2 | -5.8 | 6.7e-09 | -0.17 | 0 | 0.11 | TRUE |
5 | GTEx | Nerve Tibial | KANSL1 | 0.31 | 0.06 | lasso | 2 | 0.13 | 3.4e-09 | 3.2 | -5.6 | 2.0e-08 | -0.21 | 0 | 0.01 | FALSE |
6 | GTEx | Testis | KANSL1 | 0.19 | 0.05 | enet | 10 | 0.09 | 6.6e-05 | 2.8 | -5.6 | 2.5e-08 | -0.53 | 0 | 0.00 | FALSE |
7 | GTEx | Thyroid | KANSL1 | 0.26 | 0.02 | enet | 16 | 0.10 | 7.8e-08 | -2.0 | -5.5 | 4.8e-08 | -0.63 | 0 | 0.01 | FALSE |