Best TWAS P=9.65e-27 · Best GWAS P=8.86e-29 conditioned to 7.42e-06
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Esophagus Muscularis | NEGR1 | 0.13 | 0.04 | lasso | 3 | 0.05 | 5.1e-04 | -6.1 | 6.5 | 6.3e-11 | -0.45 | 0.62 | 0.23 | FALSE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | NEGR1 | 0.24 | 0.15 | lasso | 8 | 0.22 | 1.3e-27 | 6.6 | 10.7 | 9.6e-27 | -0.78 | 0.06 | 0.94 | TRUE |