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Comparative body size at age 10
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chr1:71,163,715-73,435,171
Best TWAS P=9.65e-27 · Best GWAS P=8.86e-29 conditioned to 7.42e-06
71.5M
72M
72.5M
73M
73.5M
0
5
10
15
20
25
30
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
ROSMAP
Brain Pre-frontal Cortex
NEGR1
0.24
0.15
lasso
8
0.22
1.3e-27
6.6
10.7
9.6e-27
-0.78
0.06
0.94
TRUE
1
GTEx
Esophagus Muscularis
NEGR1
0.13
0.04
lasso
3
0.05
5.1e-04
-6.1
6.5
6.3e-11
-0.45
0.62
0.23
FALSE