[Hub]/) : Traits : Comparative height size at age 10 :

chr1:45,393,277-47,339,113

Best TWAS P=1.17e-08 · Best GWAS P=1.17e-08 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Cells Transformed fibroblasts IPP 0.04 0.08 lasso 1 0.08 2.3e-06 5.7 -5.7 1.2e-08 -1.00 0.03 0.97 TRUE
2 GTEx Colon Transverse GPBP1L1 0.06 0.01 lasso 6 0.01 8.3e-02 5.4 -5.4 8.5e-08 -0.88 0.08 0.78 FALSE
3 GTEx Esophagus Mucosa GPBP1L1 0.04 0.02 lasso 3 0.02 1.5e-02 5.5 -5.5 3.3e-08 -0.97 0.05 0.79 FALSE
4 GTEx Esophagus Muscularis CCDC17 0.04 0.04 lasso 6 0.01 9.1e-02 5.7 -5.7 1.6e-08 -1.00 0.04 0.91 FALSE
5 GTEx Lung GPBP1L1 0.04 0.02 enet 14 0.02 5.8e-03 5.5 -5.5 3.7e-08 -0.89 0.07 0.88 FALSE
6 GTEx Muscle Skeletal GPBP1L1 0.03 0.02 enet 19 0.03 7.2e-04 5.1 -5.2 2.4e-07 -0.84 0.07 0.88 FALSE
7 GTEx Skin Not Sun Exposed Suprapubic CCDC17 0.10 0.13 lasso 6 0.13 9.6e-08 5.5 -5.7 1.3e-08 -0.98 0.03 0.97 FALSE
8 GTEx Skin Not Sun Exposed Suprapubic GPBP1L1 0.09 0.02 enet 11 0.02 3.5e-02 5.4 -5.2 2.0e-07 -0.93 0.05 0.94 FALSE
9 GTEx Skin Sun Exposed Lower leg GPBP1L1 0.03 0.00 lasso 5 0.00 4.8e-01 2.9 -5.2 1.9e-07 -0.78 0.07 0.57 FALSE
10 GTEx Testis PIK3R3 0.08 0.05 enet 7 0.06 1.5e-03 5.5 -5.3 9.4e-08 -0.99 0.07 0.88 FALSE
11 GTEx Testis IPP 0.05 0.06 enet 8 0.03 1.4e-02 5.5 5.5 3.0e-08 0.97 0.05 0.84 FALSE
12 GTEx Testis RP11-767N6.2 0.05 0.00 enet 14 0.01 1.1e-01 5.5 5.1 2.9e-07 0.86 0.07 0.72 FALSE
13 ROSMAP Brain Pre-frontal Cortex IPP 0.08 0.15 lasso 9 0.14 5.0e-18 5.3 -5.2 1.6e-07 -0.98 0.04 0.96 FALSE
14 YFS Blood CCDC17 0.04 0.02 lasso 8 0.02 6.8e-08 5.5 -5.4 8.1e-08 -0.95 0.04 0.96 FALSE
15 The Cancer Genome Atlas Breast Invasive Carcinoma GPBP1L1 0.01 0.02 lasso 2 0.02 1.2e-04 5.5 -5.5 4.5e-08 -0.98 0.03 0.93 FALSE
16 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma GPBP1L1 0.03 0.04 lasso 1 0.03 8.0e-05 5.7 -5.7 1.2e-08 -1.00 0.02 0.96 FALSE
17 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma GPBP1L1 0.07 0.10 lasso 3 0.09 6.3e-06 5.5 -5.5 4.6e-08 -0.98 0.04 0.96 FALSE
18 The Cancer Genome Atlas Prostate Adenocarcinoma GPBP1L1 0.04 0.04 blup 50 0.04 2.9e-05 5.5 -5.5 3.3e-08 -0.97 0.03 0.96 FALSE
19 The Cancer Genome Atlas Stomach Adenocarcinoma IPP 0.04 0.04 blup 47 0.04 1.4e-03 4.7 -5.2 1.6e-07 -0.95 0.03 0.77 FALSE
20 The Cancer Genome Atlas Thyroid Carcinoma GPBP1L1 0.11 0.06 lasso 3 0.06 1.6e-06 5.5 -5.7 1.5e-08 -0.98 0.02 0.98 FALSE