[Hub]/) : Traits : Comparative height size at age 10 : ← →

chr1:43,042,125-45,109,101

Best TWAS P=2.4e-10 · Best GWAS P=1.26e-14 conditioned to 1.8e-06

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
11	GTEx	Nerve Tibial	MED8	0.13	0.07	enet	11	0.16	3.6e-11	5.0	6.3	2.4e-10	0.64	0.93	0.07	TRUE
15	ROSMAP	Brain Pre-frontal Cortex	TMEM125	0.02	0.01	lasso	4	0.01	7.4e-03	4.8	-6.3	3.0e-10	-0.70	0.24	0.34	FALSE
9	GTEx	Heart Left Ventricle	MED8	0.08	0.01	lasso	3	0.01	1.2e-01	6.0	-6.2	6.0e-10	-0.80	0.04	0.78	FALSE
6	GTEx	Breast Mammary Tissue (Female)	TIE1	0.10	0.07	enet	10	0.07	3.5e-03	5.5	-6.2	6.5e-10	-0.61	0.14	0.20	FALSE
8	GTEx	Heart Left Ventricle	TIE1	0.22	0.04	lasso	11	0.04	5.3e-03	4.9	-6.0	1.5e-09	-0.65	0.38	0.56	FALSE
10	GTEx	Muscle Skeletal	RP11-7O11.3	0.05	0.02	lasso	3	0.02	7.2e-03	-4.4	6.0	2.5e-09	0.44	0.11	0.31	FALSE
13	GTEx	Testis	MED8	0.21	0.14	lasso	3	0.20	1.8e-09	-4.7	-5.5	2.9e-08	-0.45	0.99	0.00	FALSE
4	GTEx	Artery Aorta	MED8	0.10	0.05	enet	13	0.08	4.6e-05	4.9	5.5	4.3e-08	0.48	0.88	0.02	FALSE
5	GTEx	Breast Mammary Tissue	TIE1	0.08	0.06	lasso	5	0.08	7.1e-05	5.1	-5.4	5.4e-08	-0.51	0.61	0.14	FALSE
1	CommonMind	Brain Pre-frontal Cortex	ELOVL1	0.04	0.01	enet	11	0.01	6.3e-03	5.1	-5.3	9.2e-08	-0.42	0.69	0.06	FALSE
17	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	MED8	0.03	0.00	blup	38	0.01	2.1e-02	5.0	-5.3	9.3e-08	-0.53	0.01	0.52	FALSE
2	GTEx	Adipose Subcutaneous	MED8	0.07	0.00	enet	8	0.01	4.5e-02	5.0	5.3	1.3e-07	0.57	0.54	0.14	FALSE
22	The Cancer Genome Atlas	Testicular Germ Cell Tumors	MED8	0.26	0.18	blup	39	0.24	3.5e-09	5.3	-5.3	1.3e-07	-0.48	0.02	0.98	FALSE
23	The Cancer Genome Atlas	Thyroid Carcinoma	C1orf210	0.04	0.02	lasso	2	0.01	1.4e-02	5.3	5.3	1.4e-07	0.45	0.01	0.94	FALSE
19	The Cancer Genome Atlas	Brain Lower Grade Glioma	TIE1	0.02	0.02	blup	46	0.02	9.0e-04	5.1	-5.2	1.6e-07	-0.44	0.01	0.87	FALSE
7	GTEx	Cells Transformed fibroblasts	RP1-92O14.6	0.12	0.02	lasso	5	0.03	3.6e-03	4.9	-5.2	1.7e-07	-0.47	0.84	0.01	FALSE
20	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	MED8	0.03	0.01	lasso	4	0.02	6.2e-03	-4.7	-5.2	1.7e-07	-0.46	0.02	0.59	FALSE
16	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	C1orf84	0.02	0.02	blup	44	0.01	2.0e-02	5.0	-5.2	1.9e-07	-0.55	0.02	0.73	FALSE
18	The Cancer Genome Atlas	Breast Invasive Carcinoma	C1orf84	0.02	0.03	blup	46	0.03	3.4e-07	5.0	-5.2	2.1e-07	-0.50	0.04	0.96	FALSE
3	GTEx	Adipose Visceral Omentum	TIE1	0.13	0.09	lasso	4	0.06	7.5e-04	4.8	-5.2	2.5e-07	-0.45	0.56	0.06	FALSE
12	GTEx	Pancreas	HYI	0.22	0.16	enet	9	0.20	9.7e-09	-4.3	-5.2	2.5e-07	-0.40	0.97	0.00	FALSE
21	The Cancer Genome Atlas	Rectum Adenocarcinoma	HYI	0.23	0.08	blup	34	0.14	3.1e-04	-4.3	-5.2	2.5e-07	-0.44	0.03	0.38	FALSE
14	GTEx	Thyroid	TIE1	0.10	0.05	lasso	3	0.05	1.3e-04	4.8	-5.1	3.1e-07	-0.44	0.70	0.06	FALSE
24	The Cancer Genome Atlas	Thyroid Carcinoma	TIE1	0.03	0.03	blup	46	0.03	6.1e-04	5.1	-5.1	3.1e-07	-0.43	0.02	0.96	FALSE