[Hub]/) : Traits : Comparative height size at age 10 :

chr6:129,638,583-132,080,991

Best TWAS P=4.74e-46 · Best GWAS P=1.08e-40 conditioned to 0.0655

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous L3MBTL3 0.20 0.08 lasso 4 0.09 1.1e-07 13 13.6 3.3e-42 0.87 0.07 0.93 FALSE
2 GTEx Adipose Visceral Omentum L3MBTL3 0.14 0.12 lasso 2 0.15 2.8e-08 13 13.9 4.1e-44 0.89 0.04 0.96 FALSE
3 GTEx Breast Mammary Tissue L3MBTL3 0.31 0.25 lasso 7 0.23 2.8e-12 13 13.9 8.3e-44 0.85 0.06 0.94 FALSE
4 GTEx Breast Mammary Tissue RP11-73O6.3 0.27 0.22 lasso 9 0.22 1.5e-11 13 13.8 2.9e-43 0.82 0.07 0.93 FALSE
5 GTEx Breast Mammary Tissue (Male) L3MBTL3 0.31 0.24 lasso 6 0.23 5.5e-06 13 13.7 1.1e-42 0.87 0.05 0.82 FALSE
6 GTEx Breast Mammary Tissue (Male) RP11-73O6.3 0.33 0.17 lasso 4 0.12 1.3e-03 13 13.6 2.5e-42 0.80 0.04 0.77 FALSE
7 GTEx Breast Mammary Tissue (Female) L3MBTL3 0.30 0.13 lasso 5 0.14 4.5e-05 11 13.9 8.9e-44 0.84 0.01 0.97 FALSE
8 GTEx Breast Mammary Tissue (Female) RP11-73O6.3 0.29 0.08 lasso 5 0.10 5.7e-04 12 14.0 3.1e-44 0.87 0.02 0.95 FALSE
9 GTEx Cells EBV-transformed lymphocytes L3MBTL3 0.28 0.08 lasso 10 0.03 4.4e-02 13 13.1 3.2e-39 0.90 0.01 0.95 FALSE
10 GTEx Colon Transverse L3MBTL3 0.27 0.13 lasso 8 0.20 8.0e-10 13 13.7 5.6e-43 0.86 0.02 0.98 FALSE
11 GTEx Colon Transverse RP11-73O6.3 0.19 0.09 lasso 2 0.06 1.2e-03 13 13.5 2.4e-41 0.81 0.02 0.96 FALSE
12 GTEx Esophagus Mucosa L3MBTL3 0.26 0.18 lasso 2 0.23 2.7e-15 12 13.6 4.0e-42 0.82 0.16 0.84 FALSE
13 GTEx Lung L3MBTL3 0.37 0.34 lasso 4 0.38 4.1e-30 13 13.9 3.1e-44 0.88 0.07 0.93 FALSE
14 GTEx Lung RP11-73O6.3 0.15 0.08 lasso 5 0.12 2.2e-09 13 13.9 5.1e-44 0.90 0.01 0.99 FALSE
15 GTEx Nerve Tibial L3MBTL3 0.30 0.23 lasso 4 0.22 2.3e-15 13 13.7 9.6e-43 0.83 0.07 0.93 FALSE
16 GTEx Pancreas L3MBTL3 0.32 0.17 lasso 4 0.23 4.4e-10 13 13.8 2.7e-43 0.85 0.05 0.95 FALSE
17 GTEx Pituitary L3MBTL3 0.45 0.31 lasso 8 0.29 5.1e-08 11 12.7 1.1e-36 0.72 0.14 0.84 FALSE
18 GTEx Pituitary RP11-73O6.3 0.48 0.07 lasso 7 0.16 8.2e-05 11 10.9 1.7e-27 0.55 0.13 0.69 FALSE
19 GTEx Prostate L3MBTL3 0.35 0.27 lasso 5 0.17 5.9e-05 13 13.4 3.5e-41 0.83 0.02 0.91 FALSE
20 GTEx Skin Not Sun Exposed Suprapubic L3MBTL3 0.26 0.12 lasso 4 0.12 4.0e-07 11 13.3 1.8e-40 0.79 0.09 0.90 FALSE
21 GTEx Skin Sun Exposed Lower leg L3MBTL3 0.25 0.25 lasso 9 0.24 1.4e-19 13 13.4 3.2e-41 0.82 0.07 0.93 FALSE
22 GTEx Small Intestine Terminal Ileum L3MBTL3 0.37 0.20 lasso 4 0.17 1.3e-04 13 13.5 1.2e-41 0.80 0.02 0.87 FALSE
23 GTEx Spleen L3MBTL3 0.64 0.34 enet 14 0.48 6.4e-14 12 14.1 2.1e-45 0.91 0.04 0.96 FALSE
24 GTEx Spleen RP11-73O6.3 0.45 0.43 enet 21 0.42 7.7e-12 12 13.7 1.7e-42 0.83 0.33 0.66 FALSE
25 GTEx Stomach L3MBTL3 0.36 0.18 enet 27 0.20 1.1e-09 13 13.4 3.5e-41 0.89 0.00 1.00 FALSE
26 GTEx Stomach RP11-73O6.3 0.21 0.12 lasso 6 0.06 5.9e-04 13 12.5 1.2e-35 0.95 0.00 0.99 FALSE
27 GTEx Testis L3MBTL3 0.41 0.22 lasso 8 0.30 9.2e-14 13 12.3 9.3e-35 0.71 0.06 0.94 FALSE
28 GTEx Thyroid L3MBTL3 0.40 0.39 enet 9 0.43 2.8e-35 13 14.2 4.7e-46 0.90 0.07 0.93 TRUE
29 GTEx Thyroid RP11-73O6.3 0.18 0.15 lasso 3 0.20 2.3e-15 13 13.9 5.3e-44 0.91 0.02 0.98 FALSE
30 GTEx Whole Blood L3MBTL3 0.22 0.20 lasso 9 0.20 5.1e-18 13 13.8 3.3e-43 0.82 0.07 0.93 FALSE
31 GTEx Whole Blood RP11-73O6.3 0.15 0.06 lasso 8 0.04 1.1e-04 13 13.6 3.0e-42 0.81 0.02 0.95 FALSE
32 METSIM Adipose L3MBTL3 0.13 0.12 enet 22 0.12 4.8e-18 12 10.8 5.9e-27 0.74 0.65 0.35 FALSE
33 ROSMAP Brain Pre-frontal Cortex EPB41L2 0.12 0.12 blup 522 0.10 6.5e-13 3 5.4 5.7e-08 -0.04 1.00 0.00 TRUE
34 ROSMAP Brain Pre-frontal Cortex L3MBTL3 0.14 0.07 blup 609 0.08 3.8e-10 13 11.0 4.0e-28 0.69 0.02 0.98 FALSE
35 YFS Blood L3MBTL3 0.28 0.22 blup 614 0.27 1.2e-88 12 11.4 5.3e-30 0.73 1.00 0.00 FALSE
36 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma L3MBTL3 0.06 0.01 blup 114 0.04 4.0e-03 12 11.2 3.2e-29 0.76 0.07 0.48 FALSE