Best TWAS P=3.81e-54 · Best GWAS P=1.5e-57 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | GPR126 | 0.06 | 0.04 | lasso | 4 | 0.04 | 6.1e-04 | -15.3 | 15.5 | 3.8e-54 | -0.97 | 0.02 | 0.95 | TRUE |
| 2 | GTEx | Colon Transverse | GPR126 | 0.13 | -0.01 | lasso | 7 | 0.00 | 4.2e-01 | -6.6 | -6.6 | 3.4e-11 | 0.32 | 0.07 | 0.37 | FALSE |
| 3 | METSIM | Adipose | GPR126 | 0.05 | 0.01 | blup | 429 | 0.02 | 1.9e-04 | -6.5 | 12.2 | 2.8e-34 | -0.74 | 0.14 | 0.86 | FALSE |
| 4 | NTR | Blood | HIVEP2 | 0.02 | 0.01 | blup | 424 | 0.01 | 2.6e-03 | -4.6 | -8.1 | 7.6e-16 | 0.40 | 0.34 | 0.05 | FALSE |
| 5 | The Cancer Genome Atlas | Bladder Urothelial Carcinoma | GPR126 | 0.06 | 0.00 | blup | 69 | 0.01 | 4.6e-02 | -2.3 | -5.3 | 1.1e-07 | 0.42 | 0.02 | 0.07 | FALSE |
| 6 | The Cancer Genome Atlas | Breast Invasive Carcinoma | NMBR | 0.03 | 0.03 | blup | 46 | 0.02 | 3.6e-05 | 6.4 | -6.7 | 2.2e-11 | 0.13 | 0.01 | 0.99 | FALSE |
| 7 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | NMBR | 0.04 | 0.04 | enet | 9 | 0.03 | 1.7e-04 | 5.5 | -5.7 | 1.4e-08 | 0.11 | 0.03 | 0.93 | FALSE |
| 8 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | VTA1 | 0.03 | 0.02 | blup | 66 | 0.02 | 1.7e-03 | 7.1 | -6.0 | 2.7e-09 | 0.08 | 0.22 | 0.11 | FALSE |
| 9 | The Cancer Genome Atlas | Brain Lower Grade Glioma | NMBR | 0.07 | 0.05 | blup | 46 | 0.05 | 1.4e-06 | 6.6 | -5.5 | 3.4e-08 | 0.10 | 0.01 | 0.99 | FALSE |
| 10 | The Cancer Genome Atlas | Uterine Corpus Endometrial Carcinoma | NMBR | 0.09 | 0.01 | blup | 46 | 0.04 | 3.4e-02 | 6.4 | -7.1 | 1.1e-12 | 0.11 | 0.01 | 0.67 | TRUE |