[Hub]/) : Traits : Comparative height size at age 10 :

chr6:124,741,508-127,355,237

Best TWAS P=4.67e-89 · Best GWAS P=1.22e-89 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex CENPW 0.04 0.06 lasso 10 0.06 2.4e-07 19.80 -20.0 4.7e-89 -0.99 0.02 0.98 TRUE
2 CommonMind Brain Pre-frontal Cortex HEY2 0.15 0.20 lasso 10 0.21 6.7e-25 -6.70 -6.7 1.7e-11 -0.07 0.01 0.99 FALSE
3 GTEx Artery Coronary TPD52L1 0.31 -0.01 enet 19 0.05 7.0e-03 -0.71 -5.8 8.2e-09 -0.15 0.03 0.52 TRUE
4 GTEx Breast Mammary Tissue (Female) HINT3 0.39 -0.01 enet 16 0.08 2.2e-03 -4.25 -6.4 1.7e-10 -0.14 0.13 0.06 TRUE
5 GTEx Esophagus Muscularis HINT3 0.08 0.00 enet 14 0.00 2.9e-01 6.73 -6.0 2.5e-09 -0.11 0.07 0.04 FALSE
6 GTEx Heart Atrial Appendage CENPW 0.17 0.01 enet 15 0.06 1.8e-03 19.89 -13.5 1.6e-41 -0.70 0.03 0.50 FALSE
7 GTEx Pancreas HEY2 0.28 0.11 lasso 3 0.10 3.5e-05 -5.03 -5.7 1.6e-08 -0.06 0.11 0.89 FALSE
8 GTEx Skin Sun Exposed Lower leg HINT3 0.08 0.01 lasso 4 0.03 2.0e-03 -5.94 -7.1 9.2e-13 -0.19 0.22 0.14 TRUE
9 GTEx Testis HEY2 0.31 0.17 lasso 5 0.19 7.4e-09 -6.72 -6.7 1.8e-11 -0.08 0.01 0.99 FALSE
10 GTEx Thyroid HEY2 0.22 0.24 lasso 6 0.23 1.0e-17 -6.72 -6.9 4.6e-12 -0.08 0.01 0.99 FALSE
11 GTEx Vagina CENPW 0.24 -0.01 lasso 8 -0.01 7.9e-01 6.86 8.4 5.7e-17 0.40 0.04 0.06 TRUE
12 METSIM Adipose CENPW 0.02 0.02 blup 189 0.01 8.3e-03 19.89 -15.4 3.0e-53 -0.74 0.02 0.74 FALSE
13 METSIM Adipose NCOA7 0.05 0.05 enet 5 0.05 1.9e-07 5.52 8.9 8.3e-19 0.24 0.95 0.02 FALSE
14 ROSMAP Brain Pre-frontal Cortex HEY2 0.10 0.12 enet 15 0.13 9.8e-17 6.29 -6.3 2.9e-10 -0.06 0.02 0.98 TRUE
15 The Cancer Genome Atlas Breast Invasive Carcinoma TRMT11 0.03 0.03 lasso 1 0.03 3.3e-07 -5.94 5.9 2.8e-09 0.23 0.01 0.99 TRUE
16 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma CENPW 0.04 0.05 lasso 5 0.05 2.6e-06 19.92 -19.4 6.9e-84 -0.98 0.02 0.98 FALSE
17 The Cancer Genome Atlas Brain Lower Grade Glioma CENPW 0.04 0.06 blup 35 0.05 9.2e-07 19.93 -19.4 4.6e-84 -0.98 0.03 0.97 FALSE
18 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma HEY2 0.09 0.06 lasso 8 0.06 2.3e-03 -5.03 -5.2 2.3e-07 -0.04 0.04 0.72 TRUE
19 The Cancer Genome Atlas Thyroid Carcinoma HEY2 0.03 0.04 lasso 3 0.02 3.8e-03 5.99 -6.2 7.1e-10 -0.07 0.01 0.97 TRUE