[Hub]/) : Traits : Comparative height size at age 10 :

chr7:1,034,574-3,581,391

Best TWAS P=2.03e-46 · Best GWAS P=9.08e-42 conditioned to 0.399

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex AMZ1 0.19 0.12 enet 22 0.13 5.7e-16 9.1 9.6 1.3e-21 -0.44 1.00 0.00 FALSE
2 GTEx Adipose Subcutaneous GNA12 0.11 0.08 lasso 4 0.07 1.3e-06 -7.6 -8.3 1.1e-16 0.73 0.68 0.32 FALSE
3 GTEx Adipose Subcutaneous ELFN1 0.06 0.04 lasso 3 0.02 9.5e-03 5.3 5.3 1.0e-07 -0.05 0.01 0.93 TRUE
4 GTEx Artery Tibial GNA12 0.24 0.13 enet 20 0.22 3.5e-17 -13.5 -11.7 9.1e-32 0.87 0.02 0.98 FALSE
5 GTEx Cells EBV-transformed lymphocytes GNA12 0.46 0.51 lasso 5 0.50 7.9e-19 -13.1 -13.0 1.4e-38 0.93 0.52 0.48 FALSE
6 GTEx Cells Transformed fibroblasts GNA12 0.21 0.11 lasso 11 0.15 1.7e-11 -13.5 -10.2 1.9e-24 0.89 0.01 0.99 FALSE
7 GTEx Colon Sigmoid GNA12 0.14 0.05 lasso 3 0.03 3.6e-02 -7.2 -10.7 1.7e-26 0.84 0.03 0.89 FALSE
8 GTEx Colon Transverse GNA12 0.19 0.08 lasso 4 0.10 2.3e-05 7.2 -7.8 5.8e-15 0.64 0.22 0.76 FALSE
9 GTEx Esophagus Gastroesophageal Junction GNA12 0.20 0.12 lasso 6 0.12 3.4e-05 -7.6 -10.7 1.6e-26 0.85 0.05 0.93 FALSE
10 GTEx Esophagus Mucosa GNA12 0.16 0.13 lasso 3 0.13 3.0e-09 -13.2 -11.8 6.5e-32 0.89 0.01 0.99 FALSE
11 GTEx Esophagus Muscularis GNA12 0.32 0.31 lasso 3 0.34 2.1e-21 -13.5 -12.9 2.9e-38 0.97 0.00 1.00 FALSE
12 GTEx Liver AC004840.9 0.27 0.01 enet 27 0.06 7.0e-03 1.6 8.1 4.0e-16 -0.37 0.07 0.20 FALSE
13 GTEx Lung GNA12 0.16 0.08 enet 21 0.12 1.2e-09 -13.2 -10.6 3.9e-26 0.78 0.02 0.98 FALSE
14 GTEx Nerve Tibial GNA12 0.31 0.34 lasso 7 0.36 9.6e-27 -7.5 -10.2 1.2e-24 0.86 0.90 0.10 FALSE
15 GTEx Skin Sun Exposed Lower leg GNA12 0.17 0.16 lasso 3 0.18 1.3e-14 -7.3 -10.4 3.6e-25 0.88 0.12 0.88 FALSE
16 GTEx Small Intestine Terminal Ileum GNA12 0.34 0.20 lasso 5 0.16 2.4e-04 -7.5 -7.5 6.6e-14 0.73 0.08 0.74 FALSE
17 GTEx Stomach GNA12 0.18 0.16 lasso 2 0.13 6.6e-07 -7.2 -7.3 3.2e-13 0.69 0.76 0.23 FALSE
18 GTEx Whole Blood GNA12 0.09 0.01 enet 4 0.00 3.3e-01 -12.7 -12.9 5.9e-38 0.95 0.02 0.92 FALSE
19 METSIM Adipose GNA12 0.07 0.05 lasso 3 0.05 3.3e-08 -7.5 -7.5 4.3e-14 0.74 0.30 0.70 FALSE
20 NTR Blood GNA12 0.07 0.03 bslmm 597 0.06 1.3e-17 -8.8 -9.2 2.4e-20 0.64 0.93 0.07 FALSE
21 ROSMAP Brain Pre-frontal Cortex AMZ1 0.09 0.05 lasso 6 0.04 2.4e-06 -13.5 14.3 2.0e-46 -0.95 0.01 0.99 TRUE
22 YFS Blood GNA12 0.23 0.15 bslmm 570 0.25 4.5e-82 7.3 -9.2 3.6e-20 0.51 1.00 0.00 FALSE
23 The Cancer Genome Atlas Esophageal Carcinoma AMZ1 0.18 0.05 blup 69 0.05 1.4e-02 8.2 -10.8 2.8e-27 0.74 0.01 0.70 FALSE
24 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma GNA12 0.03 0.04 lasso 1 0.04 3.0e-05 -7.6 -7.6 4.1e-14 0.70 0.08 0.77 FALSE
25 The Cancer Genome Atlas Brain Lower Grade Glioma AMZ1 0.04 0.04 lasso 3 0.02 1.3e-03 8.2 9.5 2.3e-21 -0.64 0.03 0.91 FALSE
26 The Cancer Genome Atlas Lung Adenocarcinoma GNA12 0.03 0.01 enet 7 0.02 1.5e-03 5.8 -10.6 2.0e-26 0.77 0.06 0.74 FALSE
27 The Cancer Genome Atlas Prostate Adenocarcinoma AMZ1 0.08 0.01 blup 71 0.05 1.3e-05 -7.6 5.8 8.1e-09 -0.64 0.05 0.78 FALSE