Best TWAS P=1.89e-23 · Best GWAS P=6.84e-22 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Thyroid | AL391319.1 | 0.15 | 0.12 | lasso | 4 | 0.11 | 1.0e-08 | -9.6 | 10.0 | 1.9e-23 | -0.99 | 0 | 1 | TRUE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | SMOC2 | 0.24 | 0.11 | bslmm | 711 | 0.17 | 5.5e-21 | -4.1 | 5.5 | 4.8e-08 | -0.13 | 1 | 0 | TRUE |
| 3 | ROSMAP | Brain Pre-frontal Cortex | DACT2 | 0.21 | 0.03 | enet | 59 | 0.09 | 3.1e-11 | -3.5 | 5.3 | 9.6e-08 | -0.12 | 1 | 0 | TRUE |