Hub : Genes

ELFN1

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 GTEx Adipose Subcutaneous 0.057 0.026 0.0077 0.040 NA -0.001 NA 0.019 0.0003 NA 0.43 NA 0.0095
2 GTEx Cells Transformed fibroblasts 0.113 0.049 0.0063 0.001 NA -0.003 NA -0.002 0.2600 NA 0.58 NA 0.4700

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2
Bipolar Disorder (2018) 2.1 3.3 6.2 0.6 -2.5
Bipolar Disorder or Schizophrenia 1.1 2.6 4.8 -0.7 -2.2
Depressed Affect (Nagel 2018) 0.5 1.0 1.8 0.4 1.3
Depression (Nagel 2018) 0.1 0.2 0.4 -0.1 0.6
Intelligence (Savage-Jansen 2018) 0.3 0.9 1.1 0.8 1.1
Neuroticism (Nagel 2018) 0.5 1.2 1.5 1.0 1.2
Schizophrenia (2018) 0.7 1.5 1.7 -1.3 -1.1
Schizophrenia vs Biploar Disorder 0.0 0.0 0.0 0.0 0.0
Worry (Nagel 2018) 0.5 1.1 1.3 1.0 1.1
Alzheimer’s Disease (in mother) 0.1 0.2 0.3 -0.5 0.2
Alzheimer’s Disease (in father) 3.9 4.3 8.4 -2.9 0.4
Alzheimer’s Disease (including proxy) 3.8 5.5 11.0 -3.3 0.2
Crohns Disease (2017) 0.8 1.8 2.2 -1.5 -1.2
Irritable Bowel Disease (IBD) 0.8 1.9 3.5 -1.9 -0.5
Ulcerative Colitis (UC) 0.6 1.2 2.4 -1.6 0.0
Major Depression (MDD) 0.0 0.0 0.0 0.0 0.0
Reaction Time 0.2 0.3 0.7 -0.0 -0.8
Verbal and Numeric Reasoning (VNR) 0.1 0.1 0.2 0.4 -0.3
Breast Cancer 1.8 4.4 5.0 -1.9 2.2
Ovarian Cancer 4.2 5.6 6.2 2.2 2.5
Prostate Cancer 0.6 0.8 1.7 1.3 -0.0
Age at First Birth 1.0 1.5 2.4 -0.8 -1.6
Bipolar Disorder (2011) 0.0 0.0 0.0 0.0 0.0
Body Mass Index (BMI) (2010) 0.3 0.4 0.7 0.8 0.1
Coronary Artery Disease (CAD) 4.0 4.8 9.6 -3.1 0.0
Crohns Disease (2012) 0.1 0.2 0.3 0.6 0.2
Mean Putamen Volume 0.6 0.6 1.0 0.6 1.0
Fasting Glucose 1.7 2.1 4.0 -0.4 2.0
HbA1C 0.7 0.8 1.5 -1.2 0.2
HDL Cholesterol 0.0 0.0 0.0 -0.0 0.2
LDL Cholesterol 3.2 5.1 6.0 -2.1 2.4
Lupus 0.3 0.5 0.5 -0.7 -0.7
Neuroticism (2016) 0.2 0.3 0.5 -0.7 0.2
Primary Biliary Cirrhosis 0.1 0.2 0.3 -0.6 0.1
Rheumatoid Arthritis 0.2 0.3 0.5 0.1 0.7
Schizophrenia (2014) 0.9 2.0 4.0 -0.2 -2.0
Triglycerides 0.2 0.3 0.5 -0.7 0.5
Type 2 Diabetes (T2D) (2012) 1.8 2.1 3.8 1.9 0.6
Ulcerative Colitis 0.4 0.6 1.2 -1.1 0.0
Blood Eosinophil Count 1.7 13.4 19.7 -2.7 -4.4
Blood Platelet Count 1.3 15.2 29.6 -5.4 -0.9
Blood Red Count 0.9 8.5 8.8 2.9 -3.0
Blood White Count 1.1 8.0 9.2 -3.0 -2.6
Heel T-Score 0.1 0.4 0.7 0.4 0.9
BMI 0.4 2.3 4.2 0.6 -2.1
Height 1.7 32.0 63.5 8.0 -0.6
Waist Hip Ratio (WHR) 0.2 1.1 2.2 0.0 -1.5
Systolic Blood Pressure 0.0 0.2 0.4 -0.1 0.6
Smoking Status 0.4 1.0 1.8 -1.4 -0.3
Allergy or Eczema 1.0 2.6 5.0 -0.3 -2.2
Cardiovascular Disease 0.5 1.6 3.1 -1.8 0.3
Hypothyroidism (self reported) 0.4 0.8 1.1 -0.7 1.1
Respiratory disease 0.0 0.1 0.2 -0.4 0.1
Type 2 Diabetes (T2D) (2018) 0.9 1.6 2.4 -0.9 1.6
Lung FEV1/FVC ratio 0.2 0.8 1.0 1.0 -0.8
Lung FVC 1.9 9.6 13.7 -3.7 2.4
Neuroticism 0.3 0.6 1.1 0.4 1.0
Chronotype (morning person) 0.3 0.6 1.0 -1.0 -0.5
Hair Pigment 0.1 1.8 3.6 -1.9 -0.1
Tanning 0.1 1.1 1.7 -1.3 -0.8
Hand grip strength (left) 0.2 0.4 0.6 -0.4 -0.8
Number of treatments/medications taken 1.5 2.7 4.8 -2.2 -0.8
Average weekly spirits intake 1.8 2.2 2.9 1.2 -1.7
Sensitivity / hurt feelings 0.4 0.7 0.9 -0.9 -0.7
Frequency of depressed mood in last 2 weeks 0.0 0.0 0.0 -0.0 0.0
Hearing difficulty/problems: Yes 1.2 1.8 2.4 -1.1 1.5
Relative age of first facial hair 0.9 1.9 2.2 -1.2 1.5
Other serious medical condition/disability diagnosed by doctor 2.4 3.1 6.2 -2.5 -0.1
Ever used hormone-replacement therapy (HRT) 0.4 0.5 1.0 -0.1 1.0
Ever had hysterectomy (womb removed) 0.6 0.7 1.4 -1.2 -0.1
Systolic blood pressure, automated reading 0.8 2.4 4.3 0.8 2.1
Eye problems/disorders: Diabetes related eye disease 2.5 2.8 5.5 0.3 -2.4
Angina 1.2 1.6 2.8 -1.7 0.5
Medication for hormone replacement therapy 2.2 2.5 5.0 -2.2 0.2
Vitamin and mineral supplements 0.5 0.6 1.1 -0.5 1.0
Supplements: Zinc 0.8 0.8 1.5 0.5 -1.2
Medication: Co-codamol 1.3 1.6 3.1 -1.8 -0.1
Medication: Metformin 0.5 0.7 1.1 -0.5 -1.1
Diabetes (father) 0.4 0.5 0.6 -0.6 -0.8
Diabetes (mother) 0.1 0.1 0.2 -0.4 -0.1
Severe depression (siblings) 1.6 1.7 3.4 -1.9 -0.2
Pack years adult smoking proportion 2.1 3.2 5.3 -2.3 -1.0
Impedance of leg (right) 0.4 1.9 3.0 -1.7 -0.9
Leg fat-free mass (left) 0.9 4.6 9.2 3.0 -0.2
Trunk fat percentage 0.0 0.0 0.1 0.3 -0.1
Hand grip strength (right) 0.2 0.6 0.9 0.6 -0.9
Townsend deprivation index at recruitment 1.3 1.8 2.7 -1.0 -1.6
Current tobacco smoking 1.1 1.8 3.6 -1.9 0.1
Average weekly fortified wine intake 0.1 0.1 0.3 0.5 0.1
Maternal smoking around birth 2.1 3.0 3.2 -1.7 -1.8
Fed-up feelings 0.2 0.4 0.8 -0.2 0.9
Frequency of unenthusiasm / disinterest in last 2 weeks 0.9 1.2 1.4 -1.0 1.2
Relative age voice broke 1.0 1.5 2.5 -1.6 0.7
Taking other prescription medications 1.0 1.6 3.2 -1.8 0.2
Age when periods started (menarche) 0.5 1.3 2.2 -0.6 -1.5
Bilateral oophorectomy (both ovaries removed) 4.1 4.7 9.4 -3.1 -0.2
Heel bone mineral density (BMD) T-score, automated (left) 0.1 0.2 0.3 0.6 0.0
Tinnitus: Yes, but not now, but have in the past 1.8 1.9 2.8 -1.1 1.7
Qualifications: CSEs or equivalent 1.4 1.8 2.3 -1.5 -1.2
Serious illness, injury or assault to yourself 0.6 0.7 1.4 -1.2 0.2
High blood pressure 0.6 1.7 2.9 -1.7 0.7
Hayfever, allergic rhinitis or eczema 0.9 1.9 3.7 -0.1 -1.9
Multivitamins +/- minerals 0.7 0.9 1.7 0.2 -1.3
Stomach or abdominal pain in last month 0.3 0.4 0.8 -0.9 -0.2
Supplements: Glucosamine 0.3 0.5 0.9 0.9 0.0
Diverticular disease/diverticulitis (self-reported) 0.0 0.1 0.1 -0.3 0.1
Medication: Atenolol 1.6 1.9 2.2 -1.5 -1.3
Medication: Levothyroxine sodium 0.4 0.7 1.0 -0.6 1.0
Sitting height 1.5 10.8 21.5 4.6 0.1
Chronic bronchitis/emphysema (father) 0.1 0.1 0.2 -0.1 -0.4
High blood pressure (mother) 0.5 0.7 1.3 1.1 -0.2
Body mass index (BMI) 0.0 0.2 0.2 -0.4 -0.5
Impedance of leg (left) 0.3 1.4 2.5 -1.6 -0.5
Leg predicted mass (left) 1.0 5.0 10.0 3.2 -0.3
Trunk fat mass 0.1 0.6 1.1 1.0 -0.3
Waist circumference 0.1 0.3 0.5 0.3 -0.7
Number of incorrect matches in round 0.4 0.6 0.9 -0.6 -0.9
Past tobacco smoking 0.5 1.0 1.9 -0.0 1.4
Alcohol usually taken with meals 0.6 0.9 1.8 -0.1 -1.4
Nervous feelings 0.2 0.4 0.7 -0.1 0.8
Frequency of tenseness / restlessness in last 2 weeks 0.1 0.1 0.2 -0.4 0.2
Hearing difficulty/problems with background noise 0.5 0.7 1.2 -0.5 1.1
Hair/balding pattern: Pattern 2 0.6 0.7 1.5 -0.1 1.2
Had menopause 0.5 0.6 0.8 0.6 0.9
Had other major operations 0.2 0.2 0.4 -0.6 -0.1
Forced vital capacity (FVC) 0.3 1.0 1.9 0.3 1.4
Heel bone mineral density (BMD) T-score, automated (right) 0.2 0.5 0.6 0.6 -0.8
Ever unenthusiastic/disinterested for a whole week 0.8 1.0 1.2 -1.1 -0.9
Qualifications: None of the above 0.5 1.0 1.6 -1.3 -0.6
Financial difficulties in last 2 years 1.0 1.3 2.7 -1.6 0.0
Mouth/teeth dental problems 0.2 0.3 0.3 0.6 0.6
Heart attack 3.1 3.9 7.8 -2.8 0.3
Allergy 0.8 1.9 2.8 1.1 1.7
Pain all over the body in last month 2.0 2.1 4.2 -2.0 -0.2
Diabetes (self-reported) 0.7 1.1 2.0 -1.4 0.5
Hayfever/allergic rhinitis (self-reported) 0.6 0.8 1.2 -0.6 -1.1
Medication: Ramipril 0.0 0.1 0.1 0.0 0.3
Medication: Simvastatin 0.7 1.0 1.8 -1.3 -0.5
Fluid intelligence score 0.0 0.0 0.1 0.1 -0.3
Illnesses of siblings 2.6 3.6 4.9 2.2 1.6
Neuroticism score 0.4 0.8 1.4 -0.3 1.2
Weight 0.3 1.6 2.9 1.7 -0.4
Impedance of arm (right) 0.1 0.3 0.6 -0.1 0.8
Arm fat percentage (right) 0.0 0.1 0.3 -0.5 -0.1
Trunk fat-free mass 0.6 3.7 7.3 2.7 -0.2
Hip circumference 0.2 0.8 1.5 1.2 0.2
Time employed in main current job 0.2 0.2 0.4 0.3 0.6
Alcohol intake versus 10 years previously 0.5 0.8 0.8 -0.9 -0.9
Father’s age at death 0.4 0.5 0.5 0.7 -0.7
Worrier / anxious feelings 2.3 4.3 8.4 -2.9 0.5
Frequency of tiredness / lethargy in last 2 weeks 0.1 0.1 0.2 -0.4 0.2
Falls in the last year 0.5 0.6 1.0 0.5 1.0
Hair/balding pattern: Pattern 3 0.4 0.6 1.0 0.5 -1.0
Number of live births 0.4 0.6 1.2 -1.1 -0.2
Forced expiratory volume in 1-second (FEV1) 0.1 0.5 1.0 0.1 1.0
Pulse rate 3.0 5.0 9.5 0.7 3.1
Happiness 2.0 2.4 4.0 -0.9 2.0
Noisy workplace 1.5 1.8 2.5 -1.1 1.6
Qualifications: A levels/AS levels or equivalent 2.8 6.2 11.6 3.4 1.0
Serious illness, injury or assault of a close relative in last 2 years 0.9 1.0 1.7 0.5 -1.3
Mouth/teeth dental problems: Dentures 0.8 1.3 1.8 -0.9 -1.3
Asthma 0.1 0.1 0.2 -0.5 0.2
Medication: Ibuprofen (e.g. Nurofen) 0.4 0.5 0.6 0.7 0.6
Medication: Cholesterol lowering 2.1 3.2 6.1 -2.5 -0.6
Depression (self-reported) 0.1 0.1 0.2 0.2 -0.4
Medication: Lansoprazole 3.4 3.9 7.6 -2.8 -0.4
Prospective memory result 0.2 0.2 0.4 0.1 -0.6
Lung cancer (father) 0.1 0.1 0.2 -0.3 -0.4
Illnesses of mother 0.2 0.2 0.4 0.6 0.3
Forced expiratory volume in 1-second (FEV1), Best measure 0.2 0.7 1.0 0.6 1.0
Pulse wave Arterial Stiffness index 1.9 2.2 3.3 1.1 1.8
Impedance of arm (left) 0.1 0.2 0.4 -0.2 0.7
Arm fat mass (right) 0.1 0.2 0.4 0.6 -0.3
Trunk predicted mass 0.6 3.7 7.2 2.7 -0.3
Standing height 1.2 11.6 23.1 4.8 0.2
Length of working week for main job 1.6 1.8 3.6 -1.9 0.1
Exposure to tobacco smoke at home 0.3 0.3 0.6 0.8 -0.1
Breastfed as a baby 0.7 0.9 1.5 1.2 0.6
Tense / ‘highly strung’ 0.0 0.0 0.0 0.0 0.1
Seen doctor (GP) for nerves, anxiety, tension or depression 1.2 1.8 3.3 -1.8 0.6
Hair/balding pattern: Pattern 4 0.3 0.6 1.1 -0.4 -1.0
Birth weight of first child 0.7 1.3 1.7 -1.3 0.9
Peak expiratory flow (PEF) 0.2 0.4 0.5 -0.4 -0.7
Pulse wave reflection index 0.6 0.8 1.5 1.2 -0.1
Ever highly irritable/argumentative for 2 days 0.6 0.7 1.3 -1.2 -0.2
Loud music exposure frequency 0.4 0.4 0.5 -0.6 0.7
Qualifications: O levels/GCSEs or equivalent 1.3 2.0 3.0 1.7 -1.0
Mouth/teeth dental problems: Bleeding gums 1.4 1.7 2.7 0.9 1.6
Blood clot in the leg (DVT) 0.4 0.5 0.6 -0.8 -0.7
Medication: Paracetamol 0.3 0.5 1.0 -1.0 -0.1
Headache pain in last month 2.2 3.7 4.7 -2.2 1.6
Medication for cholesterol, blood pressure or diabetes 1.8 2.9 4.9 2.2 0.9
Glaucoma (self-reported) 0.1 0.2 0.3 0.1 -0.5
Gout (self-reported) 0.8 1.2 1.9 1.4 0.6
Hypothyroidism/myxoedema (self-reported) 0.6 1.3 2.0 -0.7 1.4
Medication: Amlodipine 0.0 0.1 0.1 0.1 0.3
Medication: Ventolin 100micrograms inhaler 1.0 1.3 2.0 -1.4 -0.7
Birth weight 1.0 2.2 4.5 -2.1 -0.0
Chronic bronchitis/emphysema (mother) 0.8 0.9 1.3 -1.1 -0.7
High blood pressure (siblings) 0.9 1.3 2.2 -1.5 -0.6
Forced vital capacity (FVC), Best measure 0.2 0.8 1.3 0.6 1.1
Body fat percentage 0.0 0.1 0.2 -0.1 -0.4
Leg fat percentage (right) 0.3 1.2 1.3 -1.0 -1.2
Arm fat-free mass (right) 0.7 3.8 7.6 2.8 -0.3
Exposure to tobacco smoke outside home 1.7 2.3 4.5 -2.1 -0.2
Comparative body size at age 10 0.1 0.4 0.6 -0.5 0.7
Number of full brothers 0.7 0.9 1.6 -0.5 1.3
Worry too long after embarrassment 0.0 0.0 0.0 -0.1 0.1
Seen a psychiatrist for nerves, anxiety, tension or depression 0.4 0.5 1.0 0.3 -1.0
Wheeze or whistling in the chest in last year 0.9 1.7 2.7 -1.6 -0.8
Number of children fathered 0.2 0.2 0.4 0.2 -0.6
Reason for reducing amount of alcohol drunk: Health precaution 1.5 1.8 2.9 -0.8 -1.7
Age at first live birth 0.5 1.0 1.5 -0.6 -1.2
Pulse wave peak to peak time 1.5 1.8 3.1 -0.8 -1.8
Health satisfaction 3.5 4.5 6.9 -1.4 2.6
Shortness of breath walking on level ground 1.5 1.8 2.0 -1.2 1.4
Qualifications: College or University degree 1.2 3.8 5.1 2.3 1.6
Eye problems/disorders: None of the above 1.1 1.3 2.0 -1.4 -0.7
Mouth/teeth dental problems: Loose teeth 0.5 0.6 1.2 -1.1 0.3
Emphysema/chronic bronchitis 1.0 1.1 2.2 -1.5 0.1
Medication for pain relief, constipation, heartburn 1.0 1.7 2.6 1.6 -0.8
Neck or shoulder pain in last month 1.4 2.0 3.8 -2.0 0.3
Medication: Blood pressure 0.7 1.2 2.2 -1.5 0.4
Angina (self-reported) 1.1 1.4 2.0 -1.4 0.9
Migraine (self-reported) 0.8 1.0 1.3 -0.9 1.1
Medication: Ibuprofen 0.3 0.3 0.5 0.7 0.4
Medication: Allopurinol 1.1 1.5 2.9 0.4 1.7
Medication: Omeprazole 2.1 2.5 4.9 -0.1 2.2
Medication: Seretide 50 evohaler 1.5 1.7 2.9 -0.7 -1.7
Mean time to correctly identify matches 0.0 0.0 0.0 0.0 -0.1
Heart disease (mother) 0.5 0.6 1.1 -1.1 0.2
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.6 0.7 0.8 0.8 -0.9
Whole body fat mass 0.2 0.7 0.8 0.9 -0.7
Leg fat mass (right) 0.2 0.9 1.7 0.4 -1.3
Arm predicted mass (right) 0.7 3.8 7.4 2.7 -0.4
Pulse rate, automated reading 0.8 2.7 4.8 0.8 2.2
Alcohol intake frequency. 0.8 1.8 3.3 -1.8 0.5
Comparative height size at age 10 2.6 14.2 28.3 5.3 0.4
Number of full sisters 0.2 0.3 0.5 -0.7 0.0
Suffer from ‘nerves’ 0.6 0.9 1.9 1.4 -0.0
Overall health rating 0.8 1.7 3.4 -1.8 0.2
Chest pain or discomfort 0.5 0.7 1.4 -1.2 0.3
Had major operations 1.1 1.3 1.5 1.2 1.0
Age at last live birth 0.4 0.6 1.1 -1.1 -0.1
Family relationship satisfaction 1.3 1.5 3.1 0.2 1.7
Leg pain on walking 0.3 0.4 0.7 -0.9 -0.2
Qualifications: NVQ or HND or HNC or equivalent 0.3 0.4 0.8 0.2 -0.9
Commuting to job workplace: Car/motor vehicle 0.5 0.6 1.0 0.5 1.0
Illness, injury, bereavement, stress in last 2 years 0.3 0.4 0.8 0.0 -0.9
Medication: Aspirin 2.4 3.2 6.3 -2.5 0.0
Supplements: Vitamin C 1.0 1.2 2.2 1.5 -0.4
Knee pain experienced in last month 0.6 0.9 1.1 -0.9 -1.0
Hypertension (Self-reported) 0.5 1.4 2.7 -1.6 0.4
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.0 0.0 0.1 0.2 -0.0
Illnesses of father: Heart disease 2.8 3.8 6.6 -2.6 -1.0
Illnesses of siblings: Diabetes 1.5 1.9 2.0 -1.4 -1.3
Smoking status: Previous 0.2 0.3 0.5 -0.1 -0.7
Forced expiratory volume in 1-second (FEV1), predicted 3.0 6.2 9.8 3.1 -1.6
Whole body fat-free mass 0.8 4.7 9.2 3.0 -0.4
Leg fat-free mass (right) 0.9 4.8 9.6 3.1 -0.0
Arm fat percentage (left) 0.0 0.1 0.2 -0.4 -0.1
Average weekly red wine intake 0.1 0.2 0.2 -0.5 -0.3
Handedness (chirality/laterality): Left-handed 0.6 0.8 1.5 0.0 -1.2
Mood swings 0.3 0.5 0.7 -0.9 0.6
Loneliness, isolation 0.3 0.5 0.5 0.7 0.7
Long-standing illness, disability or infirmity 0.9 1.4 2.8 -1.7 0.3
Ever had bowel cancer screening 0.5 0.6 1.1 -0.1 -1.1
Diabetes diagnosed by doctor 1.2 2.0 3.3 -1.8 0.9
Ever had stillbirth, spontaneous miscarriage or termination 0.1 0.1 0.1 0.1 -0.3
Friendships satisfaction 2.0 2.4 4.9 0.1 2.2
Qualifications: nursing, teaching 0.4 0.7 1.2 -0.4 1.1
Commuting to job workplace: Walk 0.5 0.6 1.0 -1.0 0.4
Eye problems/disorders: Cataract 0.2 0.2 0.3 0.6 0.2
Mouth/teeth dental problems: Mouth ulcers 0.3 0.5 0.5 -0.7 -0.6
Medication for cholesterol 2.0 3.0 5.9 2.4 0.2
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.4 0.5 0.9 -1.0 0.4
Back pain experienced in last month 1.1 1.7 2.9 -1.7 0.6
Mineral and other dietary supplements 0.6 0.8 1.6 0.2 1.3
Breast cancer (self-reported) 0.6 0.7 1.1 0.5 1.1
Asthma (self-reported) 0.0 0.1 0.1 -0.4 0.1
Osteoporosis (self-reported) 0.1 0.1 0.1 0.3 -0.2
Osteoarthritis (self-reported) 0.5 0.6 0.7 -0.8 0.8
Medication: Aspirin 1.6 2.0 4.1 -2.0 -0.1
Medication: Gliclazide 1.5 1.7 3.2 -1.8 0.5
Illnesses of father: None of the above (group 1) 4.4 5.4 10.5 3.2 0.6
Smoking status: Current 1.0 1.5 2.9 -1.7 -0.3
Forced expiratory volume in 1-second (FEV1), predicted percentage 1.1 2.2 2.8 -1.3 1.7
Whole body water mass 0.8 4.7 9.2 3.0 -0.3
Leg predicted mass (right) 1.0 5.1 10.2 3.2 -0.0
Arm fat mass (left) 0.0 0.2 0.2 0.5 -0.3
Number of self-reported non-cancer illnesses 0.8 1.4 2.8 -1.7 0.1
Average weekly champagne plus white wine intake 0.5 0.7 1.5 1.2 0.1
Miserableness 1.2 2.0 2.2 -1.3 1.5
Guilty feelings 0.1 0.2 0.4 0.6 0.2
Wears glasses or contact lenses 1.7 1.9 3.8 -0.1 1.9
Ever taken oral contraceptive pill 0.0 0.0 0.0 0.0 -0.1
Hearing aid user 2.3 2.6 5.0 -0.3 2.2
Mother’s age at death 0.5 0.6 0.9 0.6 1.0
Financial situation satisfaction 2.2 2.7 4.2 -1.1 2.0
Tinnitus: Yes, now most or all of the time 0.1 0.1 0.2 -0.2 0.5
Commuting to job workplace: Public transport 0.7 0.8 1.5 1.2 -0.3
Eye problems/disorders: Glaucoma 0.6 0.7 1.2 1.1 -0.5
Medication: Blood pressure 0.3 0.5 0.9 -1.0 -0.3
Pain type(s) experienced in last month: Hip pain 0.3 0.4 0.8 0.9 0.3
Supplements: Fish oil (including cod liver oil) 1.6 2.0 3.8 0.5 -1.9
High cholesterol (Self-reported) 1.1 1.9 2.2 -1.5 -1.3
Medication: Bendroflumethiazide 0.8 1.2 1.9 0.7 -1.4
Medication: Paracetamol 0.9 1.3 2.6 -1.6 -0.4
Medication: Lisinopril 0.0 0.0 0.1 -0.3 -0.0
Medication: Atorvastatin 0.4 0.5 0.9 0.4 -0.9
Illnesses of father: High blood pressure 0.4 0.5 0.6 -0.6 0.8
Alcohol drinker status: Never 2.3 2.8 5.3 -2.3 -0.5
Ever smoked 0.4 0.7 1.2 -0.4 -1.1
Basal metabolic rate 0.7 4.0 7.8 2.8 -0.5
Leg fat percentage (left) 0.2 0.8 0.8 -0.9 -0.9
Arm fat-free mass (left) 0.6 3.1 5.7 2.4 -0.8
Number of operations (self-reported) 0.6 0.9 1.5 -1.2 -0.5
Average weekly beer plus cider intake 0.7 1.0 1.2 -1.1 -0.9
Irritability 0.7 1.1 1.5 0.8 1.2
Risk taking 1.6 2.3 2.5 1.4 -1.6
Ever had prostate specific antigen (PSA) test 2.9 3.4 6.7 2.6 0.3
Fractured/broken bones in last 5 years 0.8 1.0 1.7 1.3 0.5
Age started oral contraceptive pill 0.5 0.6 1.2 0.2 -1.1
Diastolic blood pressure, automated reading 1.4 4.2 5.1 2.3 1.8
Ever depressed for a whole week 2.4 2.9 5.0 -2.2 -0.9
Unable to work because of sickness or disability 4.0 5.2 10.4 -3.2 -0.3
Commuting to job workplace: Cycle 1.0 1.2 2.2 -0.4 -1.5
Myopia 1.5 2.2 4.3 2.1 0.3
Vascular/heart problems diagnosed by doctor 1.7 4.6 8.9 3.0 -0.6
Cholesterol lowering medication 0.4 0.6 0.8 -0.9 -0.6
Medication: Omeprazole (e.g. Zanprol) 3.1 3.7 7.1 -0.6 2.7
Pain experienced in last month 0.7 1.2 2.4 1.5 -0.3
Supplements: Calcium 0.4 0.4 0.8 0.2 -0.9
Basal cell carcinoma (self-reported) 0.0 0.0 0.0 0.1 -0.0
Heart attack/myocardial infarction (self-reported) 3.4 4.4 8.5 -2.9 0.5
Deep venous thrombosis (DVT) (self-reported) 0.5 0.6 1.0 -1.0 -0.5
Heart disease (siblings) 3.4 4.2 8.1 -0.5 -2.8
Alcohol drinker status: Previous 0.6 0.7 1.4 -1.2 0.3
Pack years of smoking 1.6 2.4 3.7 -1.9 -1.0
Impedance of whole body 0.1 0.5 0.9 -1.0 0.3
Leg fat mass (left) 0.2 0.9 1.6 0.5 -1.3
Arm predicted mass (left) 0.6 3.2 6.0 2.4 -0.7