TWAS hub - SNAPC4

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0560	0.0230	1.2e-03	0.042	0.024	0.030	0.034	0.050	6.8e-06	5.3e-04	1.4e-04	5.0e-05	9.0e-07
2	GTEx	Colon Transverse	0.2240	0.0760	7.6e-03	-0.006	NA	-0.006	NA	-0.005	9.5e-01	NA	9.0e-01	NA	6.5e-01
3	GTEx	Thyroid	0.3850	0.0840	1.4e-05	0.185	NA	0.191	NA	0.214	4.4e-14	NA	1.4e-14	NA	2.6e-16
4	NTR	Blood	0.0224	0.0080	5.0e-05	0.011	0.012	0.018	0.013	0.019	1.6e-04	7.4e-05	1.4e-06	2.9e-05	6.3e-07
5	YFS	Blood	0.0406	0.0144	2.0e-05	0.029	0.023	0.028	0.062	0.029	5.4e-10	3.6e-08	9.7e-10	2.1e-19	8.0e-10
6	TCGA	Colon Adenocarcinoma	0.1510	0.0980	3.8e-03	0.035	0.022	0.047	NA	-0.003	4.3e-03	2.0e-02	1.0e-03	NA	5.4e-01
7	TCGA	Kidney Renal Papillary Cell Carcinoma	0.3340	0.0970	9.4e-04	-0.004	0.083	0.026	NA	0.005	6.8e-01	1.7e-05	1.2e-02	NA	1.7e-01
8	TCGA	Brain Lower Grade Glioma	0.1317	0.0545	3.2e-05	0.045	0.042	0.061	NA	0.057	6.2e-06	1.4e-05	1.8e-07	NA	4.2e-07
9	TCGA	Pheochromocytoma and Paraganglioma	0.3950	0.1130	6.2e-04	0.117	0.082	0.082	NA	0.110	2.2e-05	3.8e-04	3.8e-04	NA	4.0e-05
10	TCGA	Prostate Adenocarcinoma	0.1625	0.0746	8.7e-04	0.024	0.029	0.025	NA	0.020	1.5e-03	4.9e-04	1.0e-03	NA	2.9e-03
11	TCGA	Thyroid Carcinoma	0.3730	0.0790	2.2e-07	0.005	0.097	0.110	NA	0.014	8.7e-02	1.0e-09	8.0e-11	NA	1.4e-02

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11
Irritable Bowel Disease (IBD)	11.0	26.2	104.0	-10.2	-0.7	-2.8	-7.5	1.5	-4.4	1.6	-7.3	-5.4	-3.4	-1.2
Crohns Disease (2017)	10.1	22.2	85.4	-9.2	-0.8	-2.0	-7.1	1.0	-4.3	1.2	-6.1	-5.5	-3.8	-1.0
Crohns Disease (2012)	9.3	15.0	52.4	0.0	0.0	0.0	-6.5	0.5	-6.0	0.9	-7.2	-4.6	-2.2	-2.7
Ulcerative Colitis	7.6	11.1	37.1	-5.9	-0.7	0.0	-3.8	1.2	-4.6	1.1	-6.1	-2.9	-0.8	-1.5
Ulcerative Colitis (UC)	5.5	10.3	41.8	-6.5	-0.3	-2.3	-4.6	1.2	-2.4	1.8	-4.7	-3.2	-1.5	-0.4
Chronotype (morning person)	4.8	11.0	25.9	-5.0	-0.8	-2.5	-3.4	-0.7	-4.7	-2.4	-5.1	-2.2	-4.0	-1.6
Fasting Glucose	4.3	5.2	13.7	2.6	2.0	1.8	3.7	1.4	3.5	0.5	2.9	1.5	1.8	0.7
Blood White Count	3.3	24.6	80.6	-9.0	-0.9	-3.3	-6.5	3.0	-6.2	-2.4	-7.7	-1.2	-4.2	-2.0
Supplements: Fish oil (including cod liver oil)	3.3	4.4	12.3	2.2	1.1	2.4	2.6	2.0	3.5	-0.6	2.5	1.9	1.8	0.3
Ever had stillbirth, spontaneous miscarriage or termination	3.2	3.5	6.7	-2.1	0.0	-1.7	-2.6	-1.8	-2.2	-1.0	-2.3	-1.7	-2.0	-1.8
Diabetes (father)	2.9	3.6	9.4	3.1	-1.5	-1.4	1.7	-0.0	1.6	1.9	1.9	1.2	2.3	2.5
Forced expiratory volume in 1-second (FEV1), predicted	2.8	5.8	13.2	-3.6	1.1	-2.3	-2.6	0.4	-3.3	-1.6	-3.2	-1.7	-2.9	-1.3
Diabetes (mother)	2.6	3.3	6.9	2.1	1.0	1.5	2.0	0.8	2.1	1.1	2.2	2.6	2.5	0.5
Glaucoma (self-reported)	2.6	3.0	6.9	-2.1	1.6	1.4	-2.2	-1.0	-1.0	-1.9	-1.3	-0.5	-2.1	-2.6
Heart attack/myocardial infarction (self-reported)	2.4	3.1	7.0	2.4	0.9	1.9	2.4	1.2	1.9	-0.7	2.6	1.6	1.6	0.2
Lung FVC	2.3	11.8	41.3	6.4	0.7	1.4	4.0	-0.1	3.3	2.1	5.8	2.1	4.0	0.9
Heart attack	2.3	3.0	7.8	2.5	0.9	1.8	2.3	1.0	1.9	-0.8	2.8	1.3	1.4	0.2
Comparative height size at age 10	2.3	12.6	30.9	-5.2	-0.2	-3.8	-5.1	-0.0	-4.4	-0.7	-5.6	-2.5	-3.4	-1.2
Diastolic blood pressure, automated reading	2.3	7.1	15.4	-3.3	-1.9	-1.6	-2.9	-1.6	-2.9	-2.5	-3.9	-1.8	-3.6	-1.9
Standing height	2.2	22.0	59.8	-7.7	1.2	-3.2	-6.3	1.5	-5.6	-2.7	-7.4	-2.5	-5.0	-2.1
Pain type(s) experienced in last month: Hip pain	2.2	2.7	5.1	1.4	1.3	1.5	2.1	2.3	2.0	0.5	1.8	0.9	1.6	1.9
Alzheimer’s Disease (in mother)	2.1	2.4	5.4	-2.2	-0.1	-0.4	-2.2	-0.3	-2.3	-1.1	-1.6	-0.5	-1.8	-2.0
Mineral and other dietary supplements	2.1	2.9	9.8	-0.3	-1.6	-3.1	-1.4	-2.5	-2.3	0.6	-1.0	-1.2	-1.6	0.4
Blood Eosinophil Count	1.9	14.6	33.1	-5.8	-0.9	0.0	-4.9	2.0	-5.7	-3.5	-5.0	-0.5	-5.3	-0.3
Respiratory disease	1.9	4.3	8.6	-2.4	-1.3	-1.5	-1.9	0.4	-2.9	-2.9	-2.7	-0.5	-2.7	-1.2
Irritability	1.9	3.2	12.7	1.8	-0.7	0.5	3.6	1.5	2.4	0.7	1.3	1.9	2.1	0.7
Diabetes (self-reported)	1.8	2.7	7.1	2.4	0.8	1.7	2.0	0.7	2.0	0.1	1.4	1.8	2.7	0.3
Father’s age at death	1.8	2.4	8.1	1.6	0.9	0.7	1.0	1.2	0.8	2.6	1.3	-0.2	1.6	2.9
Arm fat-free mass (left)	1.8	9.1	22.9	-4.3	-0.3	-2.9	-4.7	0.6	-2.9	-0.8	-4.8	-3.1	-3.0	0.5
Trunk fat-free mass	1.7	9.7	23.2	-4.5	-0.2	-2.7	-4.6	0.6	-3.4	-1.5	-4.8	-2.9	-3.5	-0.0
Trunk predicted mass	1.7	9.5	23.0	-4.5	-0.1	-2.6	-4.5	0.7	-3.4	-1.4	-4.8	-2.8	-3.5	0.0
Chest pain or discomfort	1.7	2.4	8.8	2.1	-0.6	-0.1	3.0	0.3	2.0	0.7	1.9	1.0	1.9	0.4
Height	1.6	31.1	70.4	-8.4	0.7	-3.3	-6.7	1.7	-6.0	-5.8	-8.2	-3.8	-7.7	-1.4
Sitting height	1.6	11.6	26.4	-5.1	0.8	-3.3	-4.9	0.3	-4.4	-1.2	-5.0	-2.3	-3.5	-1.2
Hearing difficulty/problems with background noise	1.6	2.6	5.9	-2.1	-0.9	-2.2	-2.4	-0.8	-1.4	-1.2	-1.7	-1.1	-2.0	-1.0
Time employed in main current job	1.6	1.9	5.4	-1.1	-0.4	-0.9	-2.3	-2.0	-1.2	0.6	-1.3	-2.1	-1.0	-0.5
Birth weight	1.6	3.5	8.3	-2.4	-1.2	-2.4	-2.3	1.6	-2.4	1.7	-2.9	0.5	0.2	-0.1
Chronic bronchitis/emphysema (mother)	1.6	1.8	5.1	-1.4	-1.4	-2.2	-1.4	0.7	-1.6	1.7	-1.6	-0.5	0.3	0.6
Illnesses of father: Heart disease	1.6	2.3	8.8	-1.5	-0.3	-3.0	-1.4	-1.6	-2.1	0.3	-1.1	-1.4	-1.0	-0.8
Mean Putamen Volume	1.5	1.7	5.2	1.9	2.3	0.0	0.5	0.0	1.8	0.4	2.1	0.6	0.8	0.9
Past tobacco smoking	1.5	2.7	8.1	-2.9	-0.0	-1.0	-1.7	0.3	-2.1	-0.7	-2.4	-1.6	-1.8	-0.8
Qualifications: O levels/GCSEs or equivalent	1.5	2.4	5.0	2.2	-0.4	-0.1	2.0	0.1	2.2	1.4	2.1	1.2	2.2	-0.2
Arm fat-free mass (right)	1.5	7.5	17.3	-3.8	0.2	-2.5	-4.2	0.2	-2.3	-1.2	-4.2	-3.2	-3.2	0.1
Arm predicted mass (right)	1.5	7.5	18.9	-3.8	0.1	-2.3	-4.1	0.4	-2.5	-1.3	-4.3	-2.9	-3.2	0.1
Smoking status: Previous	1.5	2.2	8.0	2.8	0.1	1.2	1.4	-0.4	2.0	0.0	2.5	0.9	1.0	0.8
Whole body water mass	1.5	8.4	20.5	-4.0	0.1	-2.6	-4.5	0.4	-3.2	-1.2	-4.3	-2.8	-3.2	0.0
Hearing aid user	1.5	1.7	6.1	-2.5	0.8	-0.4	-1.5	0.6	-1.0	-1.5	-1.9	-0.1	-1.5	-0.8
Arm predicted mass (left)	1.5	7.7	19.0	-3.9	0.0	-2.5	-4.4	0.7	-2.5	-0.8	-4.3	-3.1	-2.9	0.6
Medication for hormone replacement therapy	1.4	1.6	3.4	0.0	1.2	1.8	1.8	-1.0	1.1	-1.8	0.4	0.3	-1.1	-1.7
Whole body fat-free mass	1.4	8.0	19.4	-3.9	0.2	-2.5	-4.4	0.5	-3.2	-1.3	-4.2	-2.7	-3.3	-0.0
Medication: Lisinopril	1.4	1.8	4.7	-1.1	-0.0	-1.8	-1.3	-2.2	-1.2	-0.1	-0.9	-2.1	-1.3	-0.5
Heart disease (siblings)	1.4	1.7	5.9	0.0	0.4	2.3	1.4	-1.0	0.5	-2.4	1.0	-0.2	-1.6	-0.8
HbA1C	1.3	1.4	6.6	0.5	1.0	-0.2	2.0	0.8	2.6	0.7	0.8	0.0	1.1	-1.0
Hair/balding pattern: Pattern 2	1.3	1.6	4.2	-0.4	-1.5	-2.0	-0.6	0.6	1.1	2.0	-0.5	-1.2	0.6	1.8
Serious illness, injury or assault of a close relative in last 2 years	1.3	1.5	5.4	0.4	1.3	0.5	-0.2	2.3	-0.0	0.9	0.6	1.6	2.2	-0.2
Medication: Lansoprazole	1.3	1.5	3.1	-0.9	-0.5	-0.6	-1.3	-1.4	-1.0	-1.8	-1.2	-1.4	-1.2	-1.4
Exposure to tobacco smoke at home	1.3	1.4	3.0	0.4	-1.6	-0.0	-1.5	1.2	-1.7	1.4	-0.4	1.0	0.7	1.7
Pulse wave reflection index	1.3	1.6	4.7	1.2	0.7	2.2	1.3	1.7	0.5	0.3	1.7	1.6	1.0	0.4
Seen a psychiatrist for nerves, anxiety, tension or depression	1.3	1.6	4.5	-2.1	0.3	-0.6	-1.3	0.0	-1.6	-0.8	-1.8	-1.5	-1.1	-1.2
Ever taken oral contraceptive pill	1.3	1.4	5.1	0.5	0.3	0.6	1.5	2.0	0.5	0.5	0.4	2.3	1.4	1.0
Basal metabolic rate	1.3	7.4	18.7	-3.7	-0.0	-2.6	-4.3	0.5	-2.9	-1.2	-4.1	-2.5	-3.0	0.1
Triglycerides	1.2	1.9	5.8	-2.1	0.0	0.0	-2.4	2.0	-1.3	0.3	-2.0	0.0	-0.2	1.0
High blood pressure (mother)	1.2	1.7	6.4	1.4	-0.2	-0.1	1.9	-2.5	1.8	-0.9	1.2	0.1	-0.3	-1.3
Had other major operations	1.2	1.5	5.6	-0.3	-1.0	-1.5	-0.4	-2.0	0.4	-0.8	-0.7	-2.4	-1.5	-0.2
Worrier / anxious feelings	1.2	2.3	7.1	1.8	0.1	0.9	2.2	1.2	2.7	0.4	1.6	0.9	1.7	0.6
Lung cancer (father)	1.2	1.4	5.4	-0.2	-0.1	-1.3	0.9	-1.3	0.1	-2.3	0.1	0.2	-1.9	-1.5
Breastfed as a baby	1.2	1.5	6.6	1.2	-0.1	-0.7	0.1	1.1	0.2	2.0	0.9	-0.4	1.4	2.6
Mouth/teeth dental problems: Loose teeth	1.2	1.4	4.8	1.9	0.3	0.6	1.4	-0.8	1.6	0.6	2.2	0.5	0.7	-0.4
Supplements: Vitamin C	1.2	1.5	4.9	-1.5	2.2	0.5	-1.2	-0.6	0.4	-0.7	-0.3	-2.2	-1.2	-0.3
Illnesses of siblings: Diabetes	1.2	1.5	4.1	1.5	0.7	0.8	2.0	1.2	0.4	-0.0	1.4	1.6	1.5	0.2
Average weekly red wine intake	1.2	1.8	4.8	2.2	-0.2	-0.6	2.1	-0.2	2.0	0.1	2.0	0.7	0.9	1.0
Friendships satisfaction	1.2	1.4	4.0	1.5	0.9	-0.1	1.7	0.7	0.1	0.7	2.0	1.9	0.9	0.7
Commuting to job workplace: Walk	1.2	1.3	5.9	0.8	-2.4	-2.1	0.4	0.3	0.5	0.6	-0.2	1.1	0.7	1.0
Medication: Gliclazide	1.2	1.4	4.1	1.1	1.5	0.4	0.5	1.0	2.0	0.6	1.3	1.3	1.5	0.5
Ever smoked	1.2	2.1	6.4	2.5	0.0	0.4	1.4	-0.2	1.6	1.1	2.4	1.5	1.6	0.9
Fractured/broken bones in last 5 years	1.2	1.6	4.7	1.2	-0.8	0.8	2.2	1.0	1.7	1.1	0.8	0.3	1.2	1.7
Angina	1.1	1.5	3.2	1.3	1.5	0.8	1.8	-0.4	1.7	-0.6	1.7	0.7	1.0	-0.8
Prospective memory result	1.1	1.3	4.0	1.3	-0.6	-0.6	1.0	-2.0	-0.2	-1.1	0.5	-1.8	-1.5	0.5
Number of children fathered	1.1	1.3	3.6	0.9	1.3	1.9	0.7	-0.8	1.4	0.2	1.5	-1.0	0.4	1.0
Angina (self-reported)	1.1	1.5	3.3	1.4	1.4	0.8	1.8	-0.2	1.7	-0.4	1.6	0.9	1.3	-0.7
Medication: Omeprazole	1.1	1.3	6.0	-1.2	2.5	0.6	-1.7	0.1	-1.5	-0.4	-0.3	-0.1	-0.9	-0.4
Family relationship satisfaction	1.1	1.4	2.5	1.2	-0.8	-0.8	1.0	1.1	0.0	1.5	1.1	1.4	1.6	1.4
Knee pain experienced in last month	1.1	1.7	4.3	0.7	0.7	2.1	1.3	1.6	0.6	-0.1	1.1	2.1	1.3	-1.3
Type 2 Diabetes (T2D) (2018)	1.0	1.8	3.9	1.3	1.6	2.0	0.7	-0.9	1.5	-1.4	1.3	0.9	1.0	-1.6
Average weekly spirits intake	1.0	1.3	4.1	0.1	-0.7	-1.4	-1.3	-1.3	-0.5	2.0	0.1	-1.4	-0.1	1.2
Hearing difficulty/problems: Yes	1.0	1.6	3.2	-1.8	-0.4	-1.3	-1.4	-0.4	-1.4	-0.7	-1.6	-1.4	-1.5	-0.9
Frequency of unenthusiasm / disinterest in last 2 weeks	1.0	1.3	4.7	0.9	-0.6	0.4	1.3	0.7	0.2	-1.3	0.9	2.2	0.8	-1.6
Bilateral oophorectomy (both ovaries removed)	1.0	1.1	3.1	1.1	-1.6	-0.6	1.8	0.8	0.3	0.6	0.2	1.3	1.2	1.0
Tinnitus: Yes, but not now, but have in the past	1.0	1.1	3.8	2.0	-0.1	-0.2	0.9	-0.3	0.8	1.2	2.0	0.3	0.6	1.1
Mouth/teeth dental problems	1.0	1.6	4.1	-2.0	1.8	-0.1	-1.9	1.1	-1.1	0.2	-1.5	-0.4	-1.0	0.9
Ever had bowel cancer screening	1.0	1.2	2.5	-1.5	0.5	-1.3	-1.6	0.4	-1.4	1.6	-1.1	-0.9	0.4	0.3
Medication for cholesterol	1.0	1.5	3.7	0.3	-1.1	-0.5	-0.3	1.8	-1.3	1.9	1.1	1.4	1.5	0.9
Illnesses of father: None of the above (group 1)	1.0	1.2	4.8	0.8	0.6	1.5	1.3	0.8	2.2	0.0	1.4	0.6	0.8	-0.1
Medication: Atorvastatin	1.0	1.2	4.1	-0.0	1.2	0.6	-0.5	0.8	-0.7	-0.8	0.2	2.0	1.2	-2.0
Commuting to job workplace: Cycle	1.0	1.3	4.3	2.1	0.0	-0.4	1.9	0.4	-0.3	-0.3	1.3	1.6	0.1	1.2
Medication: Omeprazole (e.g. Zanprol)	1.0	1.3	6.7	-1.0	2.6	-0.0	-1.8	-0.3	-1.2	-0.5	0.1	-0.5	-1.0	-0.0
Ovarian Cancer	0.9	1.2	3.4	0.5	1.8	1.0	1.5	1.2	1.5	0.5	1.1	0.6	1.1	0.3
Rheumatoid Arthritis	0.9	1.2	4.0	1.7	0.3	0.0	1.1	-0.5	2.0	-0.3	2.0	0.8	0.5	-0.0
Smoking Status	0.9	2.2	6.2	2.5	-0.4	0.6	2.4	-0.8	1.4	0.2	2.2	1.4	1.4	-0.3
Ever used hormone-replacement therapy (HRT)	0.9	1.2	4.5	-0.6	2.1	1.9	1.2	0.3	1.4	-0.0	0.2	-0.4	0.5	-0.7
Leg fat-free mass (left)	0.9	4.7	13.8	-2.6	0.9	-2.0	-3.7	0.5	-2.7	-1.0	-2.7	-1.9	-2.6	0.1
Townsend deprivation index at recruitment	0.9	1.3	3.6	1.9	-1.2	-0.6	0.3	-0.5	0.3	1.7	0.4	-0.3	1.5	1.9
Multivitamins +/- minerals	0.9	1.2	5.1	0.1	0.6	0.6	1.0	2.3	1.2	0.5	0.9	1.2	1.6	0.4
Leg predicted mass (left)	0.9	4.7	13.9	-2.6	0.8	-1.9	-3.7	0.4	-2.7	-1.0	-2.7	-1.9	-2.6	0.1
Heel bone mineral density (BMD) T-score, automated (right)	0.9	2.2	6.6	-1.2	-2.1	-1.6	0.2	0.2	-2.6	-1.3	-1.9	0.6	-0.9	-1.5
Weight	0.9	4.4	12.5	-2.6	-0.2	-2.2	-3.5	0.5	-1.8	-0.7	-3.4	-1.9	-2.1	0.4
Alcohol intake versus 10 years previously	0.9	1.3	3.6	1.4	-0.6	-0.6	0.6	1.1	1.1	0.6	0.9	1.6	1.1	1.9
Asthma	0.9	1.8	5.1	-1.3	-1.5	-0.0	0.1	1.3	-1.4	-2.3	-2.2	0.1	-1.3	-0.3
Comparative body size at age 10	0.9	2.4	8.7	2.1	2.5	0.8	0.3	-0.1	1.5	1.6	2.9	0.4	1.2	0.5
Emphysema/chronic bronchitis	0.9	1.0	6.6	0.0	-1.4	-2.6	0.1	-0.3	0.3	0.8	-0.5	0.5	0.8	-1.0
Neck or shoulder pain in last month	0.9	1.3	6.3	1.4	0.5	0.3	2.5	0.6	0.8	-0.1	1.2	1.2	1.3	0.5
Migraine (self-reported)	0.9	1.1	2.7	1.4	0.1	-0.7	1.6	-0.9	1.0	-1.1	1.3	1.3	-0.6	-0.6
Qualifications: NVQ or HND or HNC or equivalent	0.9	1.1	2.6	-1.6	1.4	0.3	-1.3	0.2	-1.4	0.2	-1.1	0.3	0.1	-1.4
Leg fat-free mass (right)	0.9	5.0	15.0	-2.8	0.5	-2.2	-3.9	0.5	-2.9	-0.9	-3.0	-1.7	-2.4	-0.2
Leg predicted mass (right)	0.9	5.0	15.1	-2.8	0.6	-2.1	-3.9	0.5	-2.8	-0.8	-3.0	-1.7	-2.4	-0.2
Eye problems/disorders: Glaucoma	0.9	1.1	2.2	-1.3	0.2	0.5	-1.4	-0.8	-1.0	-0.9	-1.2	-0.3	-1.5	-1.3
Medication: Blood pressure	0.9	1.7	4.2	-0.5	-0.6	-1.6	-1.3	-1.9	-0.5	-0.7	-2.0	-2.1	-1.2	0.2
Alcohol drinker status: Never	0.9	1.1	5.2	0.0	1.1	1.6	0.3	-0.1	-0.3	-2.3	0.4	0.5	-0.9	-1.2
Alcohol drinker status: Previous	0.9	1.1	3.8	-1.2	0.8	-1.2	-0.4	-0.3	-0.5	-0.7	-2.0	-0.0	-0.0	-1.9
Breast Cancer	0.8	2.0	8.6	1.4	0.1	0.8	0.4	1.1	1.0	1.9	1.3	1.6	2.9	0.3
Blood Red Count	0.8	7.6	20.6	-3.0	-0.8	-1.6	-3.0	-2.0	-3.6	-3.4	-2.7	-1.2	-4.5	-2.2
Allergy or Eczema	0.8	2.0	5.4	-1.1	0.7	-1.3	-0.6	-2.1	-2.0	-1.3	-1.0	-1.2	-2.3	-1.0
Frequency of depressed mood in last 2 weeks	0.8	1.2	3.2	-0.6	-0.5	1.4	-0.6	1.2	-0.8	0.7	-0.3	1.4	1.6	-1.8
Ever unenthusiastic/disinterested for a whole week	0.8	0.9	3.9	-1.0	0.0	-2.0	-0.6	-0.9	-1.1	-0.1	-1.0	-0.0	-0.5	-1.3
Pain all over the body in last month	0.8	0.8	4.5	-1.0	-2.1	-0.1	-0.1	0.5	0.0	-1.1	-0.8	0.8	-0.3	-0.7
Fluid intelligence score	0.8	1.6	3.3	-1.1	-0.1	1.3	-1.2	1.5	-1.5	-1.8	-1.4	1.2	-0.4	-1.3
Illnesses of siblings	0.8	1.1	3.4	-1.5	-0.2	-0.1	-1.8	-0.1	-1.2	0.5	-1.3	-1.5	-0.7	-0.2
Pulse rate	0.8	1.3	4.6	-1.0	-0.4	-0.3	-1.7	-0.9	-0.7	-0.6	-1.3	-2.1	-1.5	0.4
Happiness	0.8	1.0	2.1	1.3	0.7	-1.2	0.0	0.3	-0.6	1.0	0.9	1.5	1.5	0.3
Noisy workplace	0.8	1.0	2.2	1.2	-1.1	-0.6	0.5	1.5	1.3	-0.3	0.4	1.1	0.5	1.4
Tense / ‘highly strung’	0.8	1.3	4.4	-1.7	-1.1	-0.2	-0.9	0.3	-2.1	0.1	-1.6	-0.5	-0.5	-1.4
Gout (self-reported)	0.8	1.1	3.7	-1.1	0.2	-0.3	-0.4	-1.3	0.3	-1.9	-0.7	0.0	-1.5	-1.4
Wheeze or whistling in the chest in last year	0.8	1.4	7.3	-0.6	-0.1	1.3	-0.0	0.1	-0.7	-2.7	-0.2	0.9	-1.2	-1.8
Reason for reducing amount of alcohol drunk: Health precaution	0.8	0.9	2.8	0.8	0.4	0.3	0.8	1.1	1.4	0.0	1.7	1.5	0.5	0.2
Eye problems/disorders: None of the above	0.8	0.9	3.2	0.9	-1.5	-0.3	0.1	1.2	-0.3	0.8	0.5	0.4	1.1	1.8
Number of full sisters	0.8	1.0	3.5	-1.3	-0.1	0.5	0.1	-0.6	-0.7	-1.9	-1.3	-0.9	-1.6	-0.3
Loneliness, isolation	0.8	1.1	3.0	-1.6	1.1	0.7	-1.2	1.2	-1.7	0.1	-0.6	0.8	0.0	-0.9
Asthma (self-reported)	0.8	1.7	4.7	-1.4	-1.4	-0.4	-0.1	1.0	-1.4	-2.2	-2.1	-0.2	-1.5	-0.4
Commuting to job workplace: Public transport	0.8	1.0	3.0	-0.2	-1.5	-1.1	0.3	-1.1	-1.1	-0.7	-0.9	-0.3	-0.7	-1.7
Risk taking	0.8	1.2	4.1	-0.4	-1.0	-1.6	-1.5	-1.1	0.2	0.9	0.2	-2.0	-0.9	0.2
Alzheimer’s Disease (in father)	0.7	0.7	3.8	-0.3	0.4	2.0	-0.8	1.2	0.0	0.1	-0.3	0.0	1.2	-0.6
Alzheimer’s Disease (including proxy)	0.7	1.0	3.7	-1.1	-0.2	1.0	-1.5	-0.0	-1.2	-0.9	-0.8	-0.1	-0.5	-1.9
Schizophrenia (2014)	0.7	1.5	5.1	0.2	1.5	0.0	0.1	2.3	1.4	0.4	0.9	1.8	1.8	0.6
Ever had hysterectomy (womb removed)	0.7	0.8	2.0	0.6	-0.1	0.8	-0.1	1.0	1.3	1.1	0.2	-0.1	1.1	1.4
Systolic blood pressure, automated reading	0.7	1.9	6.1	0.2	-1.5	0.4	-1.2	-2.5	-0.9	-1.5	-0.8	-1.8	-1.9	-0.9
Eye problems/disorders: Diabetes related eye disease	0.7	0.8	2.5	0.3	0.9	0.5	0.3	-1.6	0.3	-0.9	-0.4	-1.1	-0.9	-1.2
Heel bone mineral density (BMD) T-score, automated (left)	0.7	1.5	3.8	-0.9	-1.4	-1.1	0.9	-0.3	-1.6	-1.8	-1.2	-0.0	-1.0	-2.0
Stomach or abdominal pain in last month	0.7	0.8	2.8	-0.8	1.7	0.2	-1.0	-0.9	-1.2	-0.5	0.3	-0.5	-0.6	-1.3
Medication: Levothyroxine sodium	0.7	1.2	3.3	1.6	-1.1	0.6	1.8	-1.7	-0.4	-1.2	0.3	0.4	0.1	-0.9
Financial difficulties in last 2 years	0.7	0.9	1.7	0.9	1.0	1.2	0.7	1.0	1.1	-1.2	1.0	1.3	0.3	0.1
Medication: Ramipril	0.7	0.9	3.2	0.0	1.1	0.7	0.4	1.8	0.8	-0.2	0.3	1.6	1.0	0.2
Hip circumference	0.7	3.1	12.0	-1.8	-1.3	-2.2	-3.5	0.3	-1.0	-0.0	-2.4	-1.5	-1.5	1.0
Falls in the last year	0.7	0.9	2.4	-1.2	-1.3	-1.0	-0.5	-0.8	-0.2	0.2	-1.5	-1.6	-0.9	0.0
Mouth/teeth dental problems: Dentures	0.7	1.2	3.4	1.2	-1.1	0.4	1.9	-0.9	1.8	-1.0	0.8	-0.5	0.2	-0.7
Seen doctor (GP) for nerves, anxiety, tension or depression	0.7	1.1	3.7	-0.2	0.9	1.0	-0.0	1.9	-0.1	1.0	0.8	1.7	1.4	0.0
Headache pain in last month	0.7	1.1	5.3	0.9	-0.5	-2.3	1.1	-1.8	-0.2	-0.4	0.7	0.4	-0.4	-0.8
Exposure to tobacco smoke outside home	0.7	0.9	4.0	0.7	0.2	1.5	-0.5	0.8	-0.8	0.2	0.8	2.0	0.9	0.0
Medication: Allopurinol	0.7	0.9	3.0	-1.1	0.8	-0.9	-0.7	-0.6	-0.1	-1.7	-0.8	-0.3	-1.5	-0.7
Medication: Seretide 50 evohaler	0.7	0.8	2.6	-0.9	-1.5	-0.2	0.3	0.2	-0.1	-1.2	-1.6	-1.0	-0.9	-0.1
Mean time to correctly identify matches	0.7	1.4	5.6	1.9	-1.2	0.3	2.4	0.2	1.5	-0.6	1.4	0.3	0.0	-0.0
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.7	0.8	3.0	0.6	0.7	-0.2	0.5	-0.0	1.7	-1.7	0.6	0.9	-0.8	-0.3
Illness, injury, bereavement, stress in last 2 years	0.7	0.8	3.8	1.0	0.0	0.5	1.9	-0.2	1.3	-0.2	0.6	1.2	0.1	0.7
Handedness (chirality/laterality): Left-handed	0.7	0.8	2.4	-1.1	-1.0	0.0	0.0	0.7	0.5	0.3	-1.5	1.5	0.6	-0.8
Diabetes diagnosed by doctor	0.7	1.1	3.1	1.7	0.2	0.8	1.5	-0.3	1.4	-0.2	0.7	0.9	1.8	0.1
Mouth/teeth dental problems: Mouth ulcers	0.7	1.1	3.8	1.9	-0.8	1.1	1.2	0.0	1.3	-0.5	1.5	0.4	0.4	0.1
Osteoporosis (self-reported)	0.7	0.9	3.8	-0.2	1.9	1.2	0.3	0.9	1.1	1.0	1.1	0.4	0.2	0.0
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.7	1.6	5.6	2.2	0.7	0.3	0.8	-0.0	1.9	0.3	2.4	0.5	1.2	0.6
Financial situation satisfaction	0.7	0.8	2.9	0.8	0.5	-0.7	-1.0	-0.6	-0.2	1.7	0.8	-0.5	0.9	1.3
Ever had prostate specific antigen (PSA) test	0.7	0.9	1.6	-1.3	0.3	-1.1	-1.2	0.9	-0.6	1.1	-1.1	0.9	0.4	0.5
Pain experienced in last month	0.7	1.2	2.9	-0.6	-0.5	-1.6	-1.7	-0.5	-0.7	1.5	-1.3	-1.2	0.1	1.0
Basal cell carcinoma (self-reported)	0.7	0.8	2.3	-0.9	1.5	1.2	-0.4	1.4	0.0	-0.9	0.2	0.4	-0.9	0.3
Intelligence (Savage-Jansen 2018)	0.6	1.7	5.9	-0.9	0.0	1.9	-0.3	0.9	-1.3	-2.4	-0.7	0.9	-0.8	-2.0
Reaction Time	0.6	1.1	3.4	1.6	-1.2	-0.5	1.8	0.2	1.2	-0.9	1.4	-0.5	-0.7	-0.1
Verbal and Numeric Reasoning (VNR)	0.6	1.4	4.0	-0.1	0.5	2.0	-0.2	1.6	-0.5	-1.5	-0.1	1.7	0.7	-1.5
HDL Cholesterol	0.6	0.9	3.3	1.2	0.0	0.0	1.2	0.4	1.3	-0.5	1.8	1.3	0.4	-0.4
Lupus	0.6	1.0	2.3	1.1	-0.8	-1.0	0.8	-0.5	0.8	1.5	-0.3	1.2	1.5	0.7
Neuroticism (2016)	0.6	0.9	3.1	-1.5	-0.9	-0.4	-0.3	1.3	-1.7	0.3	-1.3	0.3	0.2	-0.4
Other serious medical condition/disability diagnosed by doctor	0.6	0.8	2.0	0.9	-0.4	-1.0	0.9	1.1	0.1	1.2	0.7	0.9	1.4	0.1
Vitamin and mineral supplements	0.6	0.8	3.1	1.1	-1.8	-0.9	-0.0	-1.5	-0.8	0.3	-0.3	-0.3	-0.5	0.5
Taking other prescription medications	0.6	0.9	3.6	-0.2	-0.5	-0.3	1.1	-0.9	-0.6	-1.9	-0.8	-0.4	-1.1	-1.1
Serious illness, injury or assault to yourself	0.6	0.7	2.5	0.4	0.9	-0.8	-0.7	0.0	-0.6	1.4	0.0	-0.3	0.7	1.6
Supplements: Glucosamine	0.6	0.8	5.3	-0.6	0.7	2.3	0.3	0.8	0.3	-0.6	-0.3	0.0	0.7	-1.0
Diverticular disease/diverticulitis (self-reported)	0.6	0.7	2.3	-0.2	-1.2	-1.1	-0.7	0.5	-0.1	1.2	-0.4	-0.1	0.8	1.5
Medication: Atenolol	0.6	0.8	3.3	0.8	-1.8	-1.0	0.7	0.7	0.2	-0.1	-0.7	0.6	1.1	0.7
Allergy	0.6	1.3	3.7	0.8	-0.1	1.1	-0.2	0.8	1.9	1.5	1.3	0.5	1.7	1.0
Qualifications: A levels/AS levels or equivalent	0.6	1.3	5.0	2.2	-0.5	-0.5	0.9	-0.1	1.6	0.2	1.8	1.2	0.8	0.5
Illnesses of mother	0.6	0.7	2.7	1.0	0.2	0.7	0.4	0.7	0.4	-1.2	0.9	0.2	-0.7	1.6
Loud music exposure frequency	0.6	0.6	1.8	0.5	-1.1	-1.3	0.8	0.5	0.1	0.5	-0.2	1.1	1.0	-0.1
Medication: Amlodipine	0.6	0.9	2.4	1.5	-0.1	0.7	1.4	-1.4	1.5	0.4	0.7	-0.0	0.5	0.4
Medication: Ventolin 100micrograms inhaler	0.6	0.8	2.9	-0.2	-0.9	1.3	1.0	1.1	0.6	-1.7	-0.0	-0.2	-0.4	-0.2
Shortness of breath walking on level ground	0.6	0.7	3.6	0.6	-0.9	0.3	0.6	-0.6	0.8	-1.9	-0.5	0.2	-0.9	-0.5
Leg pain on walking	0.6	0.8	2.5	1.6	-1.0	-0.9	0.8	0.8	-0.6	0.4	0.7	0.7	1.0	0.7
Breast cancer (self-reported)	0.6	0.7	2.6	0.9	-1.0	-0.8	0.6	1.0	1.6	0.1	0.0	0.6	0.5	1.0
Average weekly beer plus cider intake	0.6	0.9	3.2	1.2	-1.3	1.1	1.8	0.3	0.5	-0.9	-0.2	0.7	0.4	-0.1
Age started oral contraceptive pill	0.6	0.8	2.4	-1.2	1.6	0.5	-0.7	1.1	-0.4	-0.5	-0.4	-1.4	-0.7	0.1
Myopia	0.6	0.9	4.5	-0.3	2.1	0.8	-1.2	-0.5	-0.4	-1.2	0.2	-0.3	-0.8	-1.0
Cholesterol lowering medication	0.6	0.9	3.0	-0.1	1.2	0.9	0.1	-1.2	0.6	-1.1	-1.0	-1.7	-0.4	-0.3
Bipolar Disorder (2018)	0.5	0.8	2.1	1.4	-1.0	0.0	1.4	-0.7	-0.2	0.3	1.4	0.5	0.8	0.1
Schizophrenia (2018)	0.5	1.1	4.2	-1.1	1.3	0.0	-0.7	2.0	0.3	-0.4	-0.0	1.8	0.8	-0.2
Waist Hip Ratio (WHR)	0.5	2.4	6.7	2.1	1.4	0.2	2.6	-1.8	2.0	-1.9	1.4	-0.5	-0.5	-0.1
Lung FEV1/FVC ratio	0.5	2.3	9.5	1.3	-1.8	-1.5	0.0	0.6	1.0	2.2	-0.1	0.1	1.8	3.1
Sensitivity / hurt feelings	0.5	0.9	2.2	-1.1	0.2	0.8	-0.1	1.5	0.6	-1.3	-0.4	1.3	0.1	-1.2
Medication: Co-codamol	0.5	0.6	4.2	1.0	-0.6	0.4	2.1	0.5	0.2	-0.1	0.1	0.5	0.7	0.3
Fed-up feelings	0.5	1.0	3.0	0.6	-0.0	0.9	1.4	1.0	0.6	-1.7	0.0	1.5	0.2	-0.9
Qualifications: CSEs or equivalent	0.5	0.6	2.5	0.0	0.5	-1.0	0.8	-0.5	0.1	1.0	0.5	0.7	1.6	-0.9
Hayfever, allergic rhinitis or eczema	0.5	1.0	3.4	-0.2	0.8	-1.1	0.4	-1.0	-1.7	-1.4	-0.3	-0.1	-1.8	-0.2
Nervous feelings	0.5	0.9	2.4	-0.9	0.2	0.7	-0.9	-0.5	-0.7	-1.4	0.1	-0.8	-1.6	-1.5
Frequency of tenseness / restlessness in last 2 weeks	0.5	0.7	2.8	0.7	-0.3	0.1	-0.0	1.7	0.1	0.0	1.4	1.3	0.9	-0.1
Medication: Simvastatin	0.5	0.7	2.5	-0.1	0.4	0.1	0.8	-1.5	0.4	-0.9	-1.1	-1.6	-0.5	-0.4
Frequency of tiredness / lethargy in last 2 weeks	0.5	0.8	2.4	1.0	-0.1	0.0	0.7	0.8	1.0	-0.1	0.7	1.4	1.5	-1.1
Number of live births	0.5	0.7	2.8	0.3	1.4	1.7	0.6	0.7	0.4	-0.3	0.6	0.7	0.6	0.6
Pulse wave Arterial Stiffness index	0.5	0.6	1.5	-0.5	0.0	-0.1	-1.1	-1.1	-0.9	0.0	-0.7	-1.1	-1.2	-0.3
Birth weight of first child	0.5	0.9	4.8	-0.5	0.6	1.3	-0.3	2.2	-0.5	-0.4	-0.9	1.1	0.6	0.2
Mouth/teeth dental problems: Bleeding gums	0.5	0.6	1.7	1.2	0.3	-0.1	0.9	-0.4	0.2	0.9	1.3	1.0	1.1	-0.3
Worry too long after embarrassment	0.5	0.9	1.8	1.0	1.3	1.0	0.8	1.2	0.8	0.1	1.4	0.8	1.1	0.2
Heart disease (mother)	0.5	0.6	2.7	-1.6	-0.2	-0.9	-0.6	0.5	-0.2	0.5	-1.2	0.2	0.2	-1.1
Whole body fat mass	0.5	1.9	7.8	-1.3	0.2	-1.7	-2.8	0.2	-0.5	0.2	-1.9	-1.4	-1.0	1.2
Pulse rate, automated reading	0.5	1.5	6.3	-2.5	-0.0	-0.6	-1.4	-0.5	-1.1	-0.1	-1.7	-1.1	-1.1	-1.1
Age at last live birth	0.5	0.7	2.7	0.6	1.7	1.3	-0.3	-0.2	0.6	0.3	0.8	-0.8	-0.3	0.8
Commuting to job workplace: Car/motor vehicle	0.5	0.6	2.3	0.5	1.5	0.7	-0.6	0.3	1.0	0.4	1.1	0.2	0.9	0.2
Medication: Aspirin	0.5	0.6	1.6	0.7	1.0	-0.8	1.3	-0.6	0.8	0.8	0.2	-0.2	1.0	0.5
Mood swings	0.5	1.0	2.6	-0.7	-1.6	-0.1	0.1	1.5	-1.2	0.7	-0.9	1.3	1.0	-0.3
Qualifications: nursing, teaching	0.5	0.8	2.4	0.5	0.2	0.5	-0.6	0.0	1.1	1.2	0.5	-1.3	0.9	1.6
Back pain experienced in last month	0.5	0.7	1.8	-1.3	1.0	1.1	-0.8	-0.6	-0.3	-0.1	-0.5	-0.8	-0.6	-1.4
Osteoarthritis (self-reported)	0.5	0.6	3.3	-0.2	-0.6	0.8	0.8	1.8	-0.0	-0.3	-0.3	1.0	0.5	0.6
Medication: Aspirin	0.5	0.6	1.8	1.0	0.3	-0.7	1.3	-0.1	1.0	0.7	0.3	0.4	1.4	0.6
Miserableness	0.5	0.9	2.5	-0.1	-1.2	-0.2	0.8	1.6	-1.1	0.6	-0.6	1.4	1.4	-0.2
Wears glasses or contact lenses	0.5	0.6	2.3	0.0	1.5	0.2	0.1	-0.4	1.4	-0.6	0.6	0.7	-0.1	-1.1
Tinnitus: Yes, now most or all of the time	0.5	0.6	1.9	0.5	0.7	0.4	0.2	1.4	0.1	0.2	1.0	0.7	0.7	1.3
Number of operations (self-reported)	0.5	0.7	2.6	-0.3	1.6	-0.1	0.8	-1.1	0.3	-1.2	0.0	-0.6	-0.7	-0.5
Unable to work because of sickness or disability	0.5	0.7	3.0	1.3	-1.7	0.4	0.7	0.0	0.2	-0.8	0.4	1.0	-0.1	0.4
Leg fat mass (left)	0.5	1.8	5.6	-1.1	-0.5	-1.8	-2.4	-0.2	-0.4	-0.2	-2.0	-1.6	-1.2	0.8
Depressed Affect (Nagel 2018)	0.4	0.9	3.4	-0.1	0.8	0.7	0.6	1.4	-0.8	0.6	-0.1	1.9	1.4	-0.1
Depression (Nagel 2018)	0.4	0.7	2.9	0.0	0.5	0.4	0.2	0.4	-0.3	0.1	-0.1	1.6	1.0	-1.7
LDL Cholesterol	0.4	0.6	1.8	1.1	0.0	0.0	1.1	0.6	0.7	0.5	0.7	0.8	1.4	0.5
Cardiovascular Disease	0.4	1.4	3.0	-1.0	-0.2	-1.4	-1.1	-1.4	-0.4	-1.7	-1.1	-1.2	-1.6	-0.6
Number of treatments/medications taken	0.4	0.8	3.8	0.4	-0.5	-0.4	1.9	-0.4	0.8	-1.5	-0.5	0.4	0.1	-0.8
Pack years adult smoking proportion	0.4	0.6	2.5	0.2	-0.1	-0.9	-0.5	-0.3	-0.7	1.6	-0.4	-0.7	1.0	0.7
Average weekly fortified wine intake	0.4	0.5	3.4	0.3	-1.1	-1.9	-0.1	-0.6	0.3	0.4	-0.0	-0.3	-0.1	0.3
Maternal smoking around birth	0.4	0.5	2.5	-1.2	-0.2	0.1	-0.9	0.2	-0.6	-0.1	-1.6	-0.3	0.1	-0.8
Chronic bronchitis/emphysema (father)	0.4	0.5	2.0	-0.4	0.1	-0.4	0.1	0.2	-0.7	-1.4	-1.2	0.4	-0.9	-0.0
Trunk fat mass	0.4	1.7	7.4	-1.3	0.5	-1.7	-2.7	0.3	-0.7	0.3	-1.8	-1.1	-0.8	1.0
Number of incorrect matches in round	0.4	0.7	3.4	0.2	1.1	-0.4	1.0	0.5	0.1	1.8	0.6	-0.1	0.7	1.1
Hayfever/allergic rhinitis (self-reported)	0.4	0.6	2.4	-0.6	0.3	-1.6	0.3	-0.1	-1.0	-0.7	-1.1	0.2	-0.8	-0.3
Hair/balding pattern: Pattern 3	0.4	0.6	1.3	1.1	0.2	0.3	0.8	-0.9	-1.0	-1.1	0.8	0.7	-0.4	-0.4
Ever highly irritable/argumentative for 2 days	0.4	0.5	2.0	-0.2	-0.5	-1.4	0.1	0.1	-0.9	1.2	-0.3	0.0	1.0	0.2
Medication: Paracetamol	0.4	0.6	2.3	-0.1	-1.5	-1.1	1.0	0.7	-0.4	-0.2	-0.7	0.9	0.5	-0.5
Number of full brothers	0.4	0.6	2.0	-0.2	0.8	1.3	0.3	0.4	0.9	-1.4	0.2	-0.2	-0.9	0.2
Health satisfaction	0.4	0.5	1.5	0.5	1.1	-1.0	-0.4	-1.2	-0.4	-0.5	0.1	-0.4	-0.2	-0.8
Leg fat mass (right)	0.4	1.7	5.9	-1.1	-0.1	-1.5	-2.4	-0.2	-0.4	-0.2	-1.9	-1.8	-1.3	1.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.4	0.4	1.1	-0.9	1.0	-0.1	0.5	-0.5	-0.5	-0.7	-0.4	-1.0	-0.8	-0.0
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.4	0.5	2.0	0.0	-0.3	-0.5	0.6	1.4	0.7	0.1	-0.1	1.2	0.6	0.1
Mother’s age at death	0.4	0.5	1.2	0.5	-0.8	-0.4	0.4	-0.7	-0.6	0.8	-0.1	-1.0	0.4	1.1
High cholesterol (Self-reported)	0.4	0.7	1.8	-0.4	0.0	-0.6	0.4	-1.4	-0.4	-1.2	-1.4	-1.2	-0.8	-0.2
Ever depressed for a whole week	0.4	0.5	2.5	1.6	-0.0	-0.3	0.7	-0.8	-0.4	-0.1	1.0	0.8	0.4	0.1
Pack years of smoking	0.4	0.6	2.8	0.2	-0.0	-0.8	-0.6	-0.3	-0.5	1.7	-0.2	-0.6	1.1	0.8
Neuroticism (Nagel 2018)	0.3	0.8	2.3	-0.3	0.7	1.4	0.6	1.5	-0.0	-0.2	0.0	1.3	0.9	-0.9
Schizophrenia vs Biploar Disorder	0.3	0.4	2.0	0.0	0.0	0.0	0.0	0.0	1.4	0.2	-0.0	1.0	1.2	0.3
Age at First Birth	0.3	0.4	1.1	0.9	-1.0	-1.0	-0.0	-0.1	0.4	0.4	0.7	-0.6	0.1	0.9
Coronary Artery Disease (CAD)	0.3	0.3	1.7	0.0	0.0	0.0	0.0	0.0	0.5	-0.3	0.0	-1.1	-0.5	-1.3
Type 2 Diabetes (T2D) (2012)	0.3	0.4	1.5	0.0	0.0	0.0	0.0	0.0	0.4	0.7	1.1	0.8	1.2	0.2
BMI	0.3	1.8	5.9	0.7	-1.2	-1.8	-1.4	-0.5	-0.3	1.7	-0.7	-1.8	0.5	2.4
Systolic Blood Pressure	0.3	1.4	2.9	-0.2	-1.4	-1.0	-1.2	-1.7	-1.1	-1.2	-1.0	-0.3	-1.5	-1.2
Neuroticism	0.3	0.6	2.0	-0.5	0.8	1.0	-0.0	1.4	-0.5	0.0	-0.2	1.4	0.8	-0.4
Medication: Metformin	0.3	0.4	2.0	0.1	1.4	0.0	0.7	-1.0	-0.2	-0.5	-0.2	-0.2	0.5	-0.7
Current tobacco smoking	0.3	0.5	1.7	0.8	-0.3	0.1	1.3	-1.1	-0.1	0.4	0.8	0.2	0.5	-0.5
Age when periods started (menarche)	0.3	0.8	2.7	0.9	-0.7	0.3	1.6	1.1	0.9	-0.0	0.2	1.2	0.9	0.6
High blood pressure	0.3	0.9	2.9	-1.0	-0.4	-0.9	-1.2	-0.6	-0.7	-0.9	-1.7	-1.1	-1.0	-0.0
Alcohol usually taken with meals	0.3	0.6	2.6	-0.7	-0.1	-0.9	0.1	-0.8	-0.4	-0.9	-0.3	-0.4	-1.6	-0.4
Had menopause	0.3	0.3	1.2	-0.2	0.7	0.5	-0.3	0.5	0.5	1.1	-0.2	-0.4	1.1	0.1
Neuroticism score	0.3	0.6	3.3	-0.4	-0.8	0.2	0.3	1.8	-0.4	-0.1	-0.6	1.1	0.7	-0.5
Medication: Ibuprofen (e.g. Nurofen)	0.3	0.4	1.2	-0.2	-0.0	-0.8	-0.5	-0.3	0.5	-1.1	0.2	0.6	-0.9	-0.9
Impedance of arm (left)	0.3	1.3	6.0	0.2	1.5	0.9	0.9	0.8	0.2	-0.4	0.9	2.4	1.0	-1.4
Arm fat mass (right)	0.3	1.2	4.8	-0.3	-0.2	-1.4	-2.2	0.6	-0.1	0.6	-1.1	-0.9	-0.2	1.8
Blood clot in the leg (DVT)	0.3	0.3	1.1	0.2	0.7	0.2	0.2	-1.1	-0.5	0.4	0.6	-0.4	0.3	-1.0
High blood pressure (siblings)	0.3	0.5	1.4	0.8	0.3	-0.4	0.6	-1.2	1.0	-0.7	0.8	0.2	0.0	-0.5
Age at first live birth	0.3	0.5	2.9	0.5	0.8	0.0	-0.3	0.8	-0.0	0.4	0.5	-0.5	-0.3	1.7
Pulse wave peak to peak time	0.3	0.3	1.5	-0.1	0.0	-0.0	0.5	1.2	0.4	-0.3	0.0	1.0	0.8	0.2
Overall health rating	0.3	0.6	1.2	-1.0	1.1	0.9	-1.1	0.6	-0.0	-0.4	-0.5	0.9	0.2	-0.8
Hypertension (Self-reported)	0.3	0.8	2.8	-0.9	-0.7	-1.0	-1.0	-0.6	-0.6	-0.9	-1.7	-0.9	-0.9	0.1
Long-standing illness, disability or infirmity	0.3	0.5	1.2	-0.6	-0.4	-0.9	0.6	-0.7	0.6	-0.8	-1.1	-0.5	-0.2	-0.7
Smoking status: Current	0.3	0.5	1.6	0.7	-0.5	-0.3	1.3	-0.6	0.2	0.8	0.5	0.6	1.0	-0.1
Arm fat mass (left)	0.3	1.2	4.8	-0.3	0.0	-1.4	-2.2	0.7	-0.0	0.6	-1.1	-1.0	-0.2	1.9
Average weekly champagne plus white wine intake	0.3	0.4	1.7	-0.6	-0.9	-0.0	-0.7	0.4	-0.0	0.2	-0.6	-1.3	-0.6	0.7
Medication: Paracetamol	0.3	0.5	1.8	0.2	-1.4	-1.0	0.7	0.7	0.1	0.4	-0.4	0.8	0.9	0.0
Illnesses of father: High blood pressure	0.3	0.3	1.0	0.9	0.1	0.5	0.8	0.4	0.2	-0.8	0.3	1.0	-0.0	0.3
Supplements: Calcium	0.3	0.3	1.2	-1.1	0.3	0.8	0.3	1.0	0.4	0.1	-0.2	0.3	0.2	-0.1
Deep venous thrombosis (DVT) (self-reported)	0.3	0.4	1.7	-0.0	0.9	0.3	0.3	-0.6	-0.5	0.4	0.3	-0.0	0.6	-1.3
Bipolar Disorder or Schizophrenia	0.2	0.6	3.1	0.1	0.3	0.0	0.2	1.1	0.1	-0.0	0.8	1.7	1.2	-0.1
Worry (Nagel 2018)	0.2	0.4	1.8	-1.0	-0.1	0.6	-0.2	0.5	-0.4	-0.1	-0.5	0.3	0.0	-1.4
Body Mass Index (BMI) (2010)	0.2	0.2	2.0	0.3	0.0	0.0	-0.4	-0.0	-0.3	0.0	0.3	0.1	-0.2	1.4
Primary Biliary Cirrhosis	0.2	0.3	2.0	-0.3	-1.4	0.0	-0.1	-0.1	-0.0	0.3	-0.1	-0.0	0.3	-1.1
Hypothyroidism (self reported)	0.2	0.5	1.9	1.1	0.6	1.1	1.4	-0.1	0.1	-0.7	0.4	0.5	0.6	0.1
Hair Pigment	0.2	5.1	15.4	-3.3	-0.9	-1.3	-3.8	0.7	-3.9	-0.1	-2.9	-1.2	-1.9	-0.0
Relative age of first facial hair	0.2	0.5	1.4	-1.1	0.9	0.7	-0.2	-0.7	-0.3	-0.1	-0.4	-1.2	-0.9	0.3
Supplements: Zinc	0.2	0.2	1.0	0.1	0.1	1.0	0.4	0.7	0.4	0.2	0.5	-0.4	0.1	0.1
Severe depression (siblings)	0.2	0.3	0.7	0.2	0.8	0.6	-0.1	0.1	0.7	0.8	0.8	-0.4	0.2	-0.1
Trunk fat percentage	0.2	0.7	3.3	-0.2	0.4	-1.2	-1.8	0.2	0.2	0.9	-0.8	-0.4	0.3	1.1
Relative age voice broke	0.2	0.3	1.5	-0.6	0.0	0.4	0.7	-0.2	1.2	0.4	-0.3	-0.2	-0.1	0.4
Body mass index (BMI)	0.2	0.7	2.9	1.0	-0.7	-0.8	-0.8	-0.0	0.8	0.8	0.0	-0.9	0.3	1.7
Impedance of leg (left)	0.2	0.9	3.3	-1.2	-1.8	-0.7	0.4	0.3	0.4	-0.6	-1.4	0.7	0.2	-1.0
Waist circumference	0.2	0.9	2.7	-0.1	-0.3	-1.2	-1.1	-0.5	0.3	-0.7	-1.4	-1.6	-1.1	1.0
Qualifications: None of the above	0.2	0.4	1.2	0.2	-1.0	-0.5	0.6	-0.5	-0.2	-1.1	-0.5	0.4	-0.7	0.7
Impedance of arm (right)	0.2	1.1	6.0	0.3	1.0	0.4	0.9	0.5	-0.3	-0.1	0.8	2.5	1.1	-1.4
Arm fat percentage (right)	0.2	0.8	3.1	1.1	-0.4	-0.6	-1.0	0.2	0.8	1.0	0.3	-0.1	0.8	1.8
Medication: Cholesterol lowering	0.2	0.3	1.3	-0.1	-0.1	-0.5	0.4	-0.4	-0.4	-0.7	-0.4	1.1	0.3	-0.9
Depression (self-reported)	0.2	0.2	0.5	0.7	-0.7	-0.5	0.3	-0.3	0.0	0.5	0.5	0.5	0.4	-0.3
Length of working week for main job	0.2	0.2	0.8	-0.3	0.3	-0.8	-0.1	-0.9	0.1	0.5	-0.1	-0.1	-0.2	-0.4
Hair/balding pattern: Pattern 4	0.2	0.4	1.3	-0.6	0.5	1.2	-0.3	0.3	0.5	-0.9	0.2	-0.5	-0.6	0.3
Peak expiratory flow (PEF)	0.2	0.5	3.1	1.1	0.4	-0.2	-0.2	0.0	0.3	-1.8	0.7	0.7	-0.5	0.1
Medication for cholesterol, blood pressure or diabetes	0.2	0.3	0.7	0.2	-0.2	0.9	-0.5	-0.3	0.7	-0.2	0.5	-0.7	-0.7	-0.3
Hypothyroidism/myxoedema (self-reported)	0.2	0.5	1.6	1.0	0.5	1.3	1.1	0.1	-0.2	-0.4	0.5	0.6	0.7	0.1
Body fat percentage	0.2	0.7	3.0	-0.1	-0.0	-1.1	-1.7	-0.0	0.3	0.6	-0.8	-0.7	0.0	1.2
Leg fat percentage (right)	0.2	0.6	1.4	-0.1	-0.7	-0.7	-1.2	-0.3	0.8	-0.1	-0.8	-1.1	-0.4	0.9
Qualifications: College or University degree	0.2	0.6	1.2	0.6	-0.9	-0.4	0.4	-0.9	-0.9	-1.0	0.2	-0.4	-1.1	-1.0
Medication for pain relief, constipation, heartburn	0.2	0.3	2.1	0.3	-0.8	1.4	-0.5	0.2	-0.1	-0.2	0.5	0.2	-0.1	-0.3
Medication: Ibuprofen	0.2	0.2	1.1	0.1	0.1	-1.1	-0.2	0.3	0.2	-0.2	0.4	0.8	0.1	-0.3
Suffer from ‘nerves’	0.2	0.4	1.8	-0.4	-1.4	-0.4	-0.1	0.3	-0.2	-0.1	-0.1	0.4	0.4	-1.1
Had major operations	0.2	0.2	0.7	-0.4	0.8	0.6	0.1	-0.0	-0.3	-0.4	0.1	0.6	-0.3	-0.5
Arm fat percentage (left)	0.2	0.7	2.8	1.1	0.0	-0.6	-0.9	0.2	1.0	0.9	0.4	-0.1	0.8	1.7
Eye problems/disorders: Cataract	0.2	0.2	0.6	-0.3	0.8	-0.4	0.6	-0.4	0.5	-0.2	0.6	-0.3	-0.4	-0.2
Number of self-reported non-cancer illnesses	0.2	0.4	2.1	-0.3	0.5	-0.2	0.3	0.2	-0.0	-1.5	-0.6	0.3	-0.8	-0.5
Guilty feelings	0.2	0.3	1.2	0.6	-0.7	1.1	-0.1	0.8	-0.1	-0.8	-0.0	0.2	-0.2	0.0
Vascular/heart problems diagnosed by doctor	0.2	0.5	1.5	0.6	0.2	0.5	0.7	0.7	-0.0	1.0	1.2	1.1	0.6	0.0
Blood Platelet Count	0.1	1.4	5.0	-1.9	-1.5	-1.2	-1.5	0.2	0.3	0.4	-2.2	-0.8	-0.4	0.1
Heel T-Score	0.1	0.8	5.1	0.4	-2.3	-1.4	0.1	-0.6	-0.6	0.5	-0.5	-0.1	0.5	-0.5
Tanning	0.1	1.3	7.8	1.4	-0.7	0.5	2.8	-1.1	0.1	-0.8	0.9	0.5	0.6	-0.9
Hand grip strength (left)	0.1	0.3	0.9	0.1	0.3	-0.8	-0.2	0.0	0.1	-0.7	-0.1	-0.9	-0.7	0.6
Impedance of leg (right)	0.1	0.4	1.2	-0.9	-1.1	-0.3	0.6	0.2	0.4	-0.7	-0.9	0.3	-0.1	-0.7
Hand grip strength (right)	0.1	0.3	1.1	0.9	0.6	-0.2	0.7	0.7	0.2	-0.3	1.1	-0.3	0.0	0.3
Forced vital capacity (FVC)	0.1	0.5	2.2	0.6	0.0	-1.2	-0.4	0.3	0.2	-1.5	0.2	0.3	-0.6	-1.1
Forced expiratory volume in 1-second (FEV1)	0.1	0.5	1.7	0.7	-0.1	-1.2	-0.6	0.7	0.3	-1.3	0.3	0.3	-0.5	-0.1
Forced expiratory volume in 1-second (FEV1), Best measure	0.1	0.4	1.4	1.2	-0.1	-0.8	-0.2	0.9	0.5	-0.9	0.7	-0.1	-0.2	0.5
Forced vital capacity (FVC), Best measure	0.1	0.4	1.3	1.0	0.3	-0.6	-0.4	0.5	0.1	-1.2	0.7	0.0	-0.3	-0.4
Medication: Blood pressure	0.1	0.2	0.7	0.4	-0.0	-0.8	0.7	0.0	0.1	0.3	-0.2	0.3	0.7	0.4
Alcohol intake frequency.	0.1	0.3	0.7	-0.2	0.7	-0.5	-0.6	0.8	-0.6	0.4	-0.0	0.4	0.6	0.4
Medication: Bendroflumethiazide	0.1	0.2	0.7	-0.5	-0.2	-0.2	-0.3	0.9	-0.2	-0.3	-0.8	0.1	0.4	-0.3
Leg fat percentage (left)	0.1	0.5	1.1	-0.1	-1.1	-0.8	-1.0	-0.2	0.9	-0.1	-0.9	-0.8	-0.1	0.6
Impedance of whole body	0.1	0.7	3.6	-0.2	0.4	0.1	0.9	0.4	0.4	-0.3	0.2	1.9	0.8	-1.2
Major Depression (MDD)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Prostate Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0

Hub : Genes

SNAPC4

Models

Trait associations