Best TWAS P=1.59e-10 · Best GWAS P=1.4e-14 conditioned to 1.86e-06
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | ROSMAP | Brain Pre-frontal Cortex | METTL15 | 0.04 | 0.03 | blup | 364 | 0.03 | 4.6e-05 | -4.2 | -5.7 | 1.2e-08 | 0.58 | 0.41 | 0.43 | FALSE |
| 2 | The Cancer Genome Atlas | Thyroid Carcinoma | KIF18A | 0.04 | 0.01 | blup | 69 | 0.03 | 1.3e-03 | -3.0 | 6.4 | 1.6e-10 | -0.61 | 0.04 | 0.73 | TRUE |