[Hub]/) : Traits : Comparative height size at age 10 : ← →

chr2:15,703-988,346

Best TWAS P=2.91e-21 · Best GWAS P=2.38e-33 conditioned to 4.11e-32

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
34	The Cancer Genome Atlas	Esophageal Carcinoma	SH3YL1	0.16	0.02	blup	67	0.08	1.9e-03	8.2	-9.5	2.9e-21	0.03	0.01	0.93	TRUE
14	GTEx	Heart Left Ventricle	SH3YL1	0.14	0.11	enet	16	0.10	8.2e-06	8.2	9.3	1.4e-20	-0.06	0.80	0.01	FALSE
29	YFS	Blood	SH3YL1	0.48	0.40	enet	100	0.46	3.2e-171	8.5	-9.1	1.4e-19	0.12	1.00	0.00	FALSE
43	The Cancer Genome Atlas	Rectum Adenocarcinoma	SH3YL1	0.51	0.29	blup	67	0.38	6.8e-10	8.6	-8.9	4.6e-19	0.06	0.01	0.99	FALSE
13	GTEx	Heart Atrial Appendage	SH3YL1	0.27	0.23	lasso	6	0.22	2.1e-10	8.4	8.6	1.2e-17	-0.10	1.00	0.00	FALSE
22	GTEx	Thyroid	SH3YL1	0.29	0.32	lasso	4	0.31	2.9e-24	8.6	-8.5	1.5e-17	0.07	1.00	0.00	FALSE
38	The Cancer Genome Atlas	Brain Lower Grade Glioma	FAM150B	0.07	0.07	lasso	2	0.06	5.8e-07	8.5	-8.5	1.5e-17	0.07	0.00	1.00	FALSE
16	GTEx	Muscle Skeletal	SH3YL1	0.12	0.10	lasso	3	0.09	4.1e-09	8.6	8.5	1.6e-17	-0.08	1.00	0.00	FALSE
19	GTEx	Skin Not Sun Exposed Suprapubic	SH3YL1	0.47	0.53	lasso	2	0.53	2.1e-33	8.5	-8.5	1.6e-17	0.06	1.00	0.00	FALSE
2	GTEx	Adipose Subcutaneous	SH3YL1	0.08	0.10	lasso	1	0.08	4.1e-07	8.5	8.5	1.7e-17	-0.06	1.00	0.00	FALSE
23	GTEx	Whole Blood	SH3YL1	0.21	0.17	lasso	6	0.18	2.6e-16	8.6	-8.5	1.7e-17	0.06	1.00	0.00	FALSE
11	GTEx	Esophagus Mucosa	SH3YL1	0.60	0.67	lasso	4	0.66	9.2e-58	8.6	-8.5	1.8e-17	0.06	1.00	0.00	FALSE
18	GTEx	Pancreas	SH3YL1	0.48	0.43	lasso	11	0.41	6.9e-19	8.6	-8.5	2.6e-17	0.06	1.00	0.00	FALSE
20	GTEx	Skin Sun Exposed Lower leg	SH3YL1	0.42	0.44	lasso	5	0.45	3.3e-41	8.5	-8.4	3.7e-17	0.06	1.00	0.00	FALSE
33	The Cancer Genome Atlas	Colon Adenocarcinoma	SH3YL1	0.32	0.34	lasso	6	0.35	2.8e-21	8.6	-8.4	5.7e-17	0.07	0.01	0.99	FALSE
25	NTR	Blood	SH3YL1	0.12	0.17	lasso	5	0.16	6.2e-51	8.5	-8.3	6.6e-17	0.06	1.00	0.00	FALSE
35	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	SH3YL1	0.24	0.25	lasso	4	0.25	8.1e-28	8.2	-8.3	7.6e-17	0.07	0.01	0.99	FALSE
9	GTEx	Colon Transverse	SH3YL1	0.36	0.25	lasso	7	0.26	1.2e-12	8.5	-8.3	9.1e-17	0.05	1.00	0.00	FALSE
31	The Cancer Genome Atlas	Breast Invasive Carcinoma	SH3YL1	0.19	0.31	lasso	5	0.32	2.5e-66	8.5	-8.3	1.1e-16	0.07	0.01	0.99	FALSE
46	The Cancer Genome Atlas	Thyroid Carcinoma	SH3YL1	0.54	0.56	lasso	4	0.57	1.1e-67	8.6	-8.3	1.4e-16	0.07	0.00	1.00	FALSE
42	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	SH3YL1	0.21	0.18	lasso	1	0.15	9.6e-07	8.2	-8.2	2.8e-16	0.07	0.01	0.99	FALSE
3	GTEx	Adipose Visceral Omentum	SH3YL1	0.15	0.03	lasso	4	0.01	6.5e-02	6.7	8.1	6.2e-16	-0.02	0.17	0.04	FALSE
21	GTEx	Stomach	SH3YL1	0.33	0.21	lasso	6	0.20	3.8e-10	8.2	-8.1	6.7e-16	0.05	1.00	0.00	FALSE
12	GTEx	Esophagus Muscularis	SH3YL1	0.30	0.23	enet	50	0.28	4.6e-17	8.6	8.1	7.7e-16	-0.05	1.00	0.00	FALSE
39	The Cancer Genome Atlas	Lung Adenocarcinoma	SH3YL1	0.17	0.24	enet	15	0.24	5.8e-28	8.6	-8.1	8.1e-16	0.07	0.01	0.99	FALSE
15	GTEx	Lung	SH3YL1	0.09	0.08	lasso	5	0.05	8.5e-05	8.2	-8.1	8.5e-16	0.10	0.82	0.02	FALSE
30	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	SH3YL1	0.25	0.15	blup	67	0.18	2.8e-15	8.6	-8.0	1.0e-15	0.06	0.01	0.99	FALSE
26	ROSMAP	Brain Pre-frontal Cortex	SH3YL1	0.15	0.12	bslmm	364	0.13	3.3e-16	-3.1	-8.0	1.7e-15	0.23	1.00	0.00	FALSE
32	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	SH3YL1	0.32	0.27	enet	14	0.28	6.6e-14	8.6	-8.0	1.9e-15	0.07	0.01	0.99	FALSE
47	The Cancer Genome Atlas	Uterine Corpus Endometrial Carcinoma	SH3YL1	0.16	0.14	lasso	2	0.09	1.8e-03	8.5	-7.9	2.4e-15	0.07	0.01	0.93	FALSE
8	GTEx	Colon Sigmoid	SH3YL1	0.20	0.14	lasso	3	0.14	1.3e-05	8.6	7.9	3.1e-15	-0.08	0.42	0.03	FALSE
45	The Cancer Genome Atlas	Stomach Adenocarcinoma	SH3YL1	0.19	0.21	enet	12	0.23	2.1e-16	8.5	-7.8	4.6e-15	0.05	0.01	0.99	FALSE
40	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	SH3YL1	0.11	0.10	lasso	5	0.10	4.5e-11	8.6	-7.7	1.2e-14	0.07	0.01	0.99	FALSE
41	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	SH3YL1	0.11	0.13	enet	8	0.13	3.7e-09	8.6	-7.5	4.4e-14	0.08	0.01	0.99	FALSE
4	GTEx	Adrenal Gland	SH3YL1	0.21	0.10	lasso	7	0.08	8.1e-04	6.7	-7.5	5.6e-14	0.12	0.24	0.12	FALSE
36	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	SH3YL1	0.16	0.04	blup	67	0.06	5.6e-07	8.5	-7.4	1.4e-13	0.03	0.01	0.99	FALSE
27	ROSMAP	Brain Pre-frontal Cortex	ACP1	0.03	0.04	lasso	2	0.02	4.7e-04	8.2	-7.3	3.1e-13	0.02	0.61	0.01	FALSE
28	ROSMAP	Brain Pre-frontal Cortex	FAM150B	0.06	0.01	bslmm	381	0.03	9.9e-05	-5.5	-7.0	3.1e-12	-0.05	0.40	0.02	FALSE
10	GTEx	Esophagus Gastroesophageal Junction	SH3YL1	0.21	0.09	lasso	7	0.14	1.3e-05	5.8	6.9	4.0e-12	0.03	0.52	0.02	FALSE
17	GTEx	Nerve Tibial	SH3YL1	0.33	0.23	enet	35	0.25	5.6e-18	8.6	6.9	5.2e-12	0.07	1.00	0.00	FALSE
5	GTEx	Artery Tibial	SH3YL1	0.10	0.02	lasso	3	0.01	2.9e-02	8.4	6.6	5.0e-11	0.08	0.65	0.02	FALSE
44	The Cancer Genome Atlas	Soft Tissue Sarcoma	SH3YL1	0.07	0.04	enet	9	0.05	1.0e-03	-5.6	6.4	1.5e-10	0.00	0.09	0.08	FALSE
24	METSIM	Adipose	SH3YL1	0.03	0.02	lasso	3	0.02	9.5e-04	5.8	6.4	2.1e-10	0.01	0.55	0.02	FALSE
37	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	SH3YL1	0.20	0.05	blup	67	0.09	9.5e-06	8.5	-6.3	3.5e-10	0.05	0.01	0.98	FALSE
7	GTEx	Cells Transformed fibroblasts	SH3YL1	0.16	0.09	lasso	7	0.10	3.3e-08	-5.7	5.7	1.0e-08	0.03	0.99	0.00	FALSE
1	CommonMind	Brain Pre-frontal Cortex	FAM110C	0.09	0.00	bslmm	232	0.01	8.2e-03	-1.1	-5.5	2.8e-08	-0.03	0.24	0.43	FALSE
6	GTEx	Artery Tibial	ACP1	0.13	0.07	lasso	12	0.11	4.4e-09	-3.1	-5.2	2.7e-07	0.13	0.99	0.00	FALSE