Best TWAS P=2.79e-08 · Best GWAS P=6.67e-09 conditioned to 0.0268
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells Transformed fibroblasts | THUMPD1 | 0.13 | 0.16 | enet | 16 | 0.16 | 4.2e-12 | -5.3 | -5.5 | 2.8e-08 | 0.81 | 0.04 | 0.96 | TRUE |
| 4 | The Cancer Genome Atlas | Ovarian Serous Cystadenocarcinoma | THUMPD1 | 0.04 | 0.04 | blup | 30 | 0.03 | 2.3e-03 | -5.3 | -5.5 | 4.7e-08 | 0.81 | 0.01 | 0.85 | FALSE |
| 2 | GTEx | Testis | AC004381.6 | 0.18 | 0.10 | lasso | 7 | 0.08 | 1.8e-04 | -5.4 | -5.4 | 6.6e-08 | 0.83 | 0.03 | 0.92 | FALSE |
| 6 | The Cancer Genome Atlas | Thyroid Carcinoma | ACSM3 | 0.06 | 0.04 | blup | 43 | 0.03 | 5.9e-04 | -5.3 | 5.4 | 8.4e-08 | -0.80 | 0.01 | 0.96 | FALSE |
| 5 | The Cancer Genome Atlas | Prostate Adenocarcinoma | ACSM3 | 0.06 | 0.06 | lasso | 13 | 0.05 | 2.8e-06 | -5.3 | 5.3 | 9.2e-08 | -0.83 | 0.01 | 0.98 | FALSE |
| 3 | ROSMAP | Brain Pre-frontal Cortex | THUMPD1 | 0.08 | 0.12 | enet | 24 | 0.12 | 3.0e-15 | -5.4 | 5.2 | 1.5e-07 | -0.82 | 0.04 | 0.96 | FALSE |