Best TWAS P=3.33e-10 · Best GWAS P=1.06e-23 conditioned to 1.07e-19
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | The Cancer Genome Atlas | Brain Lower Grade Glioma | AURKA | 0.04 | 0.03 | enet | 14 | 0.03 | 0.00050 | 4.18 | -6.3 | 3.3e-10 | -0.11 | 0.09 | 0.22 | TRUE |
| 2 | The Cancer Genome Atlas | Brain Lower Grade Glioma | C20orf108 | 0.07 | 0.00 | blup | 54 | 0.01 | 0.04120 | -0.26 | -5.6 | 2.0e-08 | -0.11 | 0.00 | 0.43 | TRUE |
| 3 | The Cancer Genome Atlas | Pancreatic Adenocarcinoma | C20orf108 | 0.18 | 0.06 | blup | 56 | 0.09 | 0.00015 | 4.18 | -5.2 | 1.7e-07 | 0.01 | 0.03 | 0.29 | FALSE |