[Hub]/) : Traits : Comparative height size at age 10 :

chr20:46,551,079-48,603,940

Best TWAS P=1.29e-30 · Best GWAS P=1.08e-30 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex ARFGEF2 0.09 0.05 lasso 8 0.10 9.2e-13 9.8 -10.5 5.3e-26 -0.76 0.48 0.52 TRUE
2 CommonMind Brain Pre-frontal Cortex CSE1L 0.08 0.07 bslmm 503 0.05 1.7e-06 -2.6 -5.4 5.8e-08 -0.55 1.00 0.00 FALSE
3 GTEx Cells Transformed fibroblasts STAU1 0.08 0.03 lasso 6 0.02 2.3e-02 7.3 8.3 6.6e-17 0.79 0.13 0.64 FALSE
4 GTEx Cells Transformed fibroblasts ZFAS1 0.06 0.05 enet 5 0.03 2.6e-03 -7.3 7.2 4.2e-13 0.28 0.37 0.34 FALSE
5 GTEx Colon Sigmoid ARFGEF2 0.15 0.12 lasso 1 0.07 2.3e-03 6.7 -6.7 1.8e-11 -0.57 0.06 0.53 FALSE
6 GTEx Colon Sigmoid CSE1L 0.18 0.12 lasso 11 0.09 4.4e-04 7.6 -7.9 3.7e-15 -0.75 0.09 0.86 FALSE
7 GTEx Colon Transverse ARFGEF2 0.11 0.07 enet 12 0.09 2.9e-05 -2.5 -6.6 3.0e-11 -0.74 0.55 0.21 FALSE
8 GTEx Esophagus Mucosa CSE1L 0.09 0.06 lasso 4 0.06 6.9e-05 7.7 -7.2 7.3e-13 -0.75 0.16 0.80 FALSE
9 GTEx Esophagus Mucosa ZFAS1 0.15 0.01 enet 16 0.01 8.9e-02 11.5 8.8 2.0e-18 0.73 0.01 0.96 FALSE
10 GTEx Lung CSE1L 0.10 0.09 lasso 5 0.08 6.6e-07 7.3 -7.0 1.8e-12 -0.68 0.95 0.03 FALSE
11 GTEx Muscle Skeletal PREX1 0.14 0.09 enet 23 0.13 2.5e-12 7.6 5.8 8.2e-09 0.45 0.99 0.01 FALSE
12 GTEx Skin Not Sun Exposed Suprapubic ZFAS1 0.16 0.04 enet 19 0.07 1.0e-04 7.4 8.1 4.5e-16 0.67 0.13 0.72 FALSE
13 GTEx Skin Sun Exposed Lower leg CSE1L 0.08 0.03 lasso 2 0.03 9.5e-04 7.9 -7.5 8.9e-14 -0.75 0.52 0.06 FALSE
14 GTEx Skin Sun Exposed Lower leg ZFAS1 0.07 0.03 enet 14 0.05 5.8e-05 11.5 9.4 5.8e-21 0.85 0.01 0.99 FALSE
15 GTEx Testis ARFGEF2 0.20 0.20 lasso 7 0.24 5.4e-11 7.3 -9.0 2.3e-19 -0.85 0.75 0.25 FALSE
16 GTEx Whole Blood ZFAS1 0.07 0.06 lasso 4 0.05 1.3e-05 -6.9 -6.8 9.6e-12 -0.19 1.00 0.00 TRUE
17 METSIM Adipose ARFGEF2 0.04 0.03 lasso 12 0.02 9.8e-05 10.1 -10.9 7.6e-28 -0.96 0.02 0.98 FALSE
18 NTR Blood NCRNA00275 0.07 0.06 lasso 4 0.08 9.7e-25 -5.9 -9.1 1.0e-19 -0.49 1.00 0.00 FALSE
19 NTR Blood SNORD12B 0.03 0.05 lasso 8 0.05 1.9e-14 11.5 -11.4 7.2e-30 -0.98 0.01 0.99 FALSE
20 ROSMAP Brain Pre-frontal Cortex CSE1L 0.04 0.02 enet 16 0.02 2.8e-03 6.7 -8.0 1.9e-15 -0.73 0.07 0.92 FALSE
21 YFS Blood CSE1L 0.06 0.05 enet 21 0.06 2.0e-19 -2.5 -5.8 4.9e-09 -0.58 1.00 0.00 FALSE
22 YFS Blood ZNFX1 0.06 0.05 lasso 3 0.05 1.4e-16 3.7 -5.5 3.1e-08 -0.54 1.00 0.00 TRUE
23 The Cancer Genome Atlas Breast Invasive Carcinoma STAU1 0.01 0.01 blup 54 0.01 6.1e-03 -7.2 -8.0 1.3e-15 -0.44 0.03 0.12 FALSE
24 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma CSE1L 0.03 0.05 lasso 1 0.03 9.3e-05 7.3 -7.3 3.4e-13 -0.70 0.30 0.62 FALSE
25 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma CSE1L 0.05 0.07 blup 50 0.07 3.2e-08 7.6 -7.5 6.0e-14 -0.75 0.40 0.60 FALSE
26 The Cancer Genome Atlas Brain Lower Grade Glioma ARFGEF2 0.05 0.04 lasso 5 0.05 3.2e-06 9.8 -9.6 5.6e-22 -0.88 0.00 1.00 TRUE
27 The Cancer Genome Atlas Lung Squamous Cell Carcinoma C20orf199 0.04 0.00 enet 8 0.02 6.4e-03 3.7 7.0 2.8e-12 0.63 0.01 0.51 FALSE
28 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma C20orf199 0.05 0.06 lasso 4 0.06 1.0e-04 11.5 11.5 1.3e-30 0.99 0.00 0.96 TRUE
29 The Cancer Genome Atlas Testicular Germ Cell Tumors CSE1L 0.13 0.03 blup 50 0.07 1.4e-03 7.3 -6.2 6.0e-10 -0.55 0.03 0.26 FALSE
30 The Cancer Genome Atlas Thyroid Carcinoma ARFGEF2 0.06 0.01 blup 79 0.03 4.2e-04 -4.2 -6.8 9.8e-12 -0.39 0.75 0.05 FALSE
31 The Cancer Genome Atlas Thyroid Carcinoma DDX27 0.08 0.05 lasso 3 0.05 1.9e-05 11.5 9.5 1.5e-21 0.91 0.01 0.99 FALSE