[Hub]/) : Traits : Comparative height size at age 10 : ← →

chr2:241,477,073-243,048,760

Best TWAS P=4.75e-15 · Best GWAS P=4.39e-14 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
52	METSIM	Adipose	BOK	0.06	0.03	lasso	6	0.03	7.8e-06	-7.2	-7.8	4.8e-15	0.12	0.05	0.93	TRUE
74	The Cancer Genome Atlas	Prostate Adenocarcinoma	SEPT2	0.40	0.06	enet	14	0.17	8.0e-18	5.4	7.7	1.6e-14	-0.53	0.03	0.97	TRUE
49	GTEx	Vagina	SEPT2	0.50	0.02	enet	35	0.06	1.5e-02	5.3	7.0	2.8e-12	-0.53	0.03	0.33	TRUE
56	ROSMAP	Brain Pre-frontal Cortex	STK25	0.09	0.06	lasso	3	0.06	1.7e-08	-7.3	-6.7	1.7e-11	0.97	0.00	1.00	TRUE
35	GTEx	Lung	AC005104.3	0.10	0.03	lasso	5	0.03	1.3e-03	5.4	6.3	2.4e-10	-0.59	0.39	0.43	TRUE
34	GTEx	Lung	SEPT2	0.42	0.33	lasso	6	0.38	2.6e-30	5.3	6.0	1.5e-09	-0.37	1.00	0.00	TRUE
62	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	FARP2	0.06	0.03	lasso	1	0.01	1.1e-02	-5.3	-5.3	1.2e-07	0.63	0.37	0.14	TRUE
61	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	SEPT2	0.05	0.01	blup	45	0.01	7.9e-03	5.4	7.6	3.1e-14	-0.75	0.01	0.92	FALSE
69	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	SEPT2	0.14	0.00	enet	7	0.02	7.7e-04	6.7	7.6	3.5e-14	-0.61	0.01	0.93	FALSE
68	The Cancer Genome Atlas	Lung Adenocarcinoma	SEPT2	0.24	0.04	blup	45	0.08	1.6e-09	5.4	7.5	6.8e-14	-0.52	0.04	0.96	FALSE
51	GTEx	Whole Blood	AC005104.3	0.07	0.02	enet	9	0.01	2.0e-02	-7.5	7.2	4.8e-13	-0.95	0.00	0.98	FALSE
60	The Cancer Genome Atlas	Breast Invasive Carcinoma	SEPT2	0.21	0.02	enet	11	0.07	4.9e-15	5.4	7.2	6.5e-13	-0.50	0.02	0.98	FALSE
72	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	SEPT2	0.18	0.11	enet	13	0.11	4.6e-05	6.8	7.2	7.4e-13	-0.57	0.00	0.97	FALSE
66	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	SEPT2	0.34	0.04	enet	14	0.12	1.3e-07	5.4	7.1	1.1e-12	-0.52	0.02	0.91	FALSE
70	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	SEPT2	0.42	0.11	enet	14	0.18	5.2e-08	5.3	7.1	1.5e-12	-0.45	0.09	0.72	FALSE
64	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	SEPT2	0.19	0.06	enet	9	0.08	1.0e-09	5.4	7.0	2.5e-12	-0.48	0.73	0.25	FALSE
9	GTEx	Artery Aorta	SEPT2	0.60	0.38	lasso	9	0.46	5.8e-28	5.3	7.0	3.4e-12	-0.50	1.00	0.00	FALSE
5	GTEx	Adipose Visceral Omentum	BOK	0.20	0.12	lasso	4	0.12	1.4e-06	-7.2	-6.9	5.4e-12	0.08	0.04	0.96	FALSE
57	ROSMAP	Brain Pre-frontal Cortex	SEPT2	0.48	0.39	enet	49	0.42	6.0e-58	5.3	6.8	9.5e-12	-0.44	1.00	0.00	FALSE
54	NTR	Blood	SEPT2	0.18	0.10	enet	34	0.14	1.0e-43	5.3	6.8	9.6e-12	-0.41	1.00	0.00	FALSE
29	GTEx	Esophagus Muscularis	SEPT2	0.57	0.34	enet	34	0.48	1.7e-32	5.3	6.8	1.2e-11	-0.52	1.00	0.00	FALSE
10	GTEx	Artery Aorta	AC005104.3	0.10	0.01	lasso	4	0.01	1.6e-01	-4.8	6.8	1.4e-11	-0.45	0.08	0.29	FALSE
50	GTEx	Whole Blood	SEPT2	0.26	0.10	lasso	5	0.12	1.8e-11	5.3	6.7	2.2e-11	-0.43	1.00	0.00	FALSE
73	The Cancer Genome Atlas	Prostate Adenocarcinoma	BOK	0.07	0.04	lasso	5	0.03	1.8e-04	6.2	-6.7	2.2e-11	0.16	0.01	0.97	FALSE
67	The Cancer Genome Atlas	Brain Lower Grade Glioma	SEPT2	0.51	0.10	enet	14	0.20	2.4e-22	5.4	6.6	3.1e-11	-0.34	0.86	0.14	FALSE
2	GTEx	Adipose Subcutaneous	SEPT2	0.45	0.36	enet	32	0.43	3.0e-38	5.3	6.6	3.4e-11	-0.42	1.00	0.00	FALSE
27	GTEx	Esophagus Gastroesophageal Junction	SEPT2	0.66	0.38	enet	29	0.50	7.1e-21	5.3	6.6	3.9e-11	-0.50	1.00	0.00	FALSE
71	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	BOK	0.19	-0.01	lasso	4	0.01	1.2e-01	-7.2	-6.6	4.9e-11	0.04	0.00	0.78	FALSE
59	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	FARP2	0.05	0.02	blup	82	0.01	6.0e-02	-5.3	-6.6	5.2e-11	0.78	0.10	0.30	FALSE
22	GTEx	Cells Transformed fibroblasts	SEPT2	0.34	0.14	lasso	6	0.32	5.5e-25	5.3	6.5	5.8e-11	-0.50	1.00	0.00	FALSE
32	GTEx	Heart Atrial Appendage	BOK	0.15	0.01	enet	18	0.08	2.1e-04	-7.1	-6.5	6.1e-11	0.26	0.05	0.48	FALSE
47	GTEx	Thyroid	SEPT2	0.55	0.43	lasso	8	0.45	4.7e-38	5.3	6.5	1.1e-10	-0.35	1.00	0.00	FALSE
46	GTEx	Testis	SEPT2	0.27	0.13	lasso	9	0.17	7.4e-08	5.4	6.4	1.3e-10	-0.52	0.97	0.02	FALSE
14	GTEx	Artery Tibial	SEPT2	0.58	0.50	lasso	13	0.58	1.4e-55	5.3	6.4	1.6e-10	-0.40	1.00	0.00	FALSE
13	GTEx	Artery Tibial	HDLBP	0.16	0.08	enet	15	0.12	8.4e-10	6.7	-6.3	2.3e-10	0.53	0.57	0.43	FALSE
44	GTEx	Spleen	SEPT2	0.57	0.40	enet	26	0.42	5.9e-12	5.3	6.3	2.5e-10	-0.35	0.98	0.01	FALSE
33	GTEx	Heart Left Ventricle	SEPT2	0.30	0.17	lasso	5	0.26	6.7e-14	5.4	6.3	2.7e-10	-0.38	1.00	0.00	FALSE
42	GTEx	Skin Not Sun Exposed Suprapubic	HDLBP	0.12	0.05	enet	9	0.08	5.2e-05	6.5	-6.3	2.8e-10	0.54	0.25	0.61	FALSE
38	GTEx	Nerve Tibial	SEPT2	0.70	0.52	lasso	11	0.58	1.4e-49	5.3	6.3	3.0e-10	-0.37	1.00	0.00	FALSE
55	ROSMAP	Brain Pre-frontal Cortex	HDLBP	0.09	0.10	lasso	4	0.10	5.9e-13	6.8	-6.3	3.4e-10	0.56	0.34	0.66	FALSE
48	GTEx	Thyroid	AC005104.3	0.11	0.06	lasso	5	0.08	1.1e-06	5.3	6.2	4.8e-10	-0.30	0.92	0.03	FALSE
36	GTEx	Muscle Skeletal	SEPT2	0.39	0.22	enet	46	0.26	1.0e-25	5.3	6.2	4.9e-10	-0.34	1.00	0.00	FALSE
19	GTEx	Brain Frontal Cortex BA9	SEPT2	0.30	-0.01	enet	32	0.02	1.1e-01	5.3	6.2	5.3e-10	-0.23	0.07	0.05	FALSE
41	GTEx	Pancreas	SEPT2	0.24	0.19	lasso	7	0.17	9.3e-08	5.4	6.2	6.3e-10	-0.36	0.94	0.04	FALSE
12	GTEx	Artery Coronary	SEPT2	0.38	0.18	enet	22	0.17	1.7e-06	5.3	6.2	7.1e-10	-0.42	0.26	0.29	FALSE
75	The Cancer Genome Atlas	Thyroid Carcinoma	SEPT2	0.76	0.25	enet	14	0.47	1.8e-50	5.4	6.1	8.8e-10	-0.32	0.93	0.07	FALSE
20	GTEx	Breast Mammary Tissue	SEPT2	0.46	0.33	enet	37	0.35	5.2e-19	5.3	6.1	9.9e-10	-0.40	1.00	0.00	FALSE
1	CommonMind	Brain Pre-frontal Cortex	SEPT2	0.52	0.29	bslmm	377	0.44	2.0e-59	5.3	6.0	1.7e-09	-0.24	1.00	0.00	FALSE
16	GTEx	Brain Cerebellar Hemisphere	FARP2	0.30	0.28	lasso	6	0.31	9.9e-09	-4.7	-6.0	2.7e-09	0.78	0.14	0.85	FALSE
26	GTEx	Colon Transverse	SEPT2	0.46	0.34	lasso	6	0.43	2.0e-22	5.3	6.0	2.7e-09	-0.32	1.00	0.00	FALSE
3	GTEx	Adipose Subcutaneous	AC005104.3	0.12	0.03	lasso	5	0.06	1.5e-05	5.3	5.9	3.3e-09	-0.46	0.10	0.81	FALSE
7	GTEx	Adrenal Gland	SEPT2	0.43	0.15	lasso	8	0.18	7.4e-07	5.4	5.9	4.3e-09	-0.34	0.99	0.01	FALSE
23	GTEx	Colon Sigmoid	SEPT2	0.55	0.49	lasso	8	0.48	4.7e-19	5.3	5.8	5.3e-09	-0.27	1.00	0.00	FALSE
30	GTEx	Heart Atrial Appendage	HDLBP	0.14	0.02	enet	15	0.07	4.3e-04	3.4	-5.8	7.7e-09	0.59	0.14	0.59	FALSE
25	GTEx	Colon Transverse	STK25	0.14	0.07	lasso	5	0.10	2.6e-05	-5.5	-5.7	1.1e-08	0.69	0.60	0.22	FALSE
15	GTEx	Artery Tibial	AC005104.3	0.18	0.14	lasso	5	0.12	6.7e-10	5.3	5.7	1.2e-08	-0.28	1.00	0.00	FALSE
45	GTEx	Stomach	SEPT2	0.24	0.27	lasso	8	0.25	3.6e-12	5.3	5.7	1.4e-08	-0.26	1.00	0.00	FALSE
18	GTEx	Brain Cerebellum	FARP2	0.47	0.51	lasso	6	0.51	2.7e-17	-5.7	-5.6	2.0e-08	0.74	0.66	0.34	FALSE
28	GTEx	Esophagus Mucosa	SEPT2	0.59	0.50	enet	37	0.56	2.7e-44	5.3	5.6	2.2e-08	-0.24	1.00	0.00	FALSE
53	METSIM	Adipose	SEPT2	0.29	0.21	bslmm	375	0.20	1.6e-29	5.3	5.6	2.3e-08	-0.25	1.00	0.00	FALSE
31	GTEx	Heart Atrial Appendage	SEPT2	0.26	0.21	lasso	5	0.20	1.7e-09	5.3	5.5	3.0e-08	-0.26	0.98	0.00	FALSE
40	GTEx	Ovary	SEPT2	0.56	0.29	lasso	5	0.23	2.4e-06	5.3	5.5	3.2e-08	-0.27	0.45	0.08	FALSE
6	GTEx	Adipose Visceral Omentum	AC005104.3	0.17	0.14	lasso	3	0.09	3.0e-05	5.3	5.5	3.5e-08	-0.24	0.98	0.01	FALSE
58	YFS	Blood	FARP2	0.01	0.01	lasso	2	0.01	5.4e-03	-5.2	-5.5	4.5e-08	0.62	0.32	0.04	FALSE
17	GTEx	Brain Cerebellar Hemisphere	HDLBP	0.29	0.09	lasso	7	0.10	1.2e-03	3.7	-5.5	5.1e-08	0.55	0.12	0.40	FALSE
43	GTEx	Skin Sun Exposed Lower leg	SEPT2	0.55	0.36	lasso	9	0.37	7.6e-32	5.3	5.4	5.4e-08	-0.27	1.00	0.00	FALSE
8	GTEx	Adrenal Gland	AC005104.3	0.22	-0.01	lasso	5	-0.01	7.7e-01	4.2	5.4	6.3e-08	-0.32	0.14	0.09	FALSE
21	GTEx	Breast Mammary Tissue (Male)	SEPT2	0.18	0.31	lasso	2	0.29	1.6e-07	5.3	5.3	9.9e-08	-0.21	0.31	0.05	FALSE
24	GTEx	Colon Sigmoid	AC005104.3	0.26	0.21	lasso	3	0.20	1.9e-07	5.3	5.3	9.9e-08	-0.21	0.81	0.01	FALSE
11	GTEx	Artery Coronary	FARP2	0.21	0.02	lasso	5	0.04	1.3e-02	-4.0	-5.3	1.1e-07	0.61	0.11	0.09	FALSE
65	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	FARP2	0.10	0.10	lasso	3	0.09	1.3e-05	-5.2	-5.2	1.8e-07	0.64	0.60	0.19	FALSE
63	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	HDLBP	0.04	0.02	blup	77	0.02	1.6e-03	2.9	-5.2	2.4e-07	0.72	0.04	0.44	FALSE
4	GTEx	Adipose Visceral Omentum	SEPT2	0.45	0.37	lasso	4	0.39	1.9e-21	5.3	5.2	2.5e-07	-0.24	1.00	0.00	FALSE
37	GTEx	Nerve Tibial	HDLBP	0.21	0.08	lasso	6	0.13	1.6e-09	3.4	-5.2	2.5e-07	0.49	0.84	0.16	FALSE
39	GTEx	Nerve Tibial	AC005104.3	0.28	0.21	enet	19	0.24	4.6e-17	5.3	5.1	2.8e-07	-0.34	1.00	0.00	FALSE