[Hub]/) : Traits : Comparative height size at age 10 : ← →

chr2:231,564,626-234,434,621

Best TWAS P=1.25e-29 · Best GWAS P=7.92e-29 conditioned to 4.85e-12

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
15	GTEx	Liver	PDE6D	0.21	0.10	lasso	4	0.09	1.8e-03	-10.6	-11.3	1.2e-29	0.82	0.02	0.89	TRUE
26	The Cancer Genome Atlas	Breast Invasive Carcinoma	DIS3L2	0.05	0.02	enet	10	0.02	3.8e-05	-5.0	-10.5	6.9e-26	0.15	0.10	0.02	TRUE
3	GTEx	Artery Coronary	RP11-690I21.1	0.24	-0.01	lasso	8	-0.01	6.8e-01	-8.3	9.1	7.0e-20	-0.57	0.07	0.15	TRUE
36	The Cancer Genome Atlas	Lung Adenocarcinoma	CHRNG	0.04	0.00	blup	58	0.00	1.3e-01	4.3	-8.3	1.1e-16	0.13	0.01	0.48	TRUE
12	GTEx	Cells Transformed fibroblasts	RP11-690I21.1	0.14	0.10	lasso	3	0.10	5.4e-08	-6.4	7.0	2.1e-12	-0.04	0.99	0.00	TRUE
23	ROSMAP	Brain Pre-frontal Cortex	DIS3L2	0.04	0.00	enet	17	0.01	6.7e-03	-10.8	6.8	8.6e-12	-0.21	0.30	0.21	TRUE
39	The Cancer Genome Atlas	Prostate Adenocarcinoma	GIGYF2	0.04	0.00	blup	103	0.02	2.1e-03	-5.7	-6.8	1.1e-11	0.01	0.06	0.72	TRUE
37	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	DIS3L2	0.06	0.02	blup	173	0.02	7.5e-04	2.3	5.8	8.5e-09	-0.35	0.37	0.06	TRUE
2	GTEx	Artery Aorta	B3GNT7	0.30	0.20	lasso	6	0.16	3.2e-09	-4.9	5.1	2.8e-07	0.01	1.00	0.00	TRUE
14	GTEx	Heart Atrial Appendage	COPS7B	0.22	0.01	lasso	6	0.01	1.3e-01	-7.7	-8.6	6.8e-18	0.76	0.04	0.42	FALSE
6	GTEx	Brain Cerebellar Hemisphere	PTMA	0.28	0.12	enet	19	0.06	1.5e-02	-7.7	8.6	1.1e-17	-0.51	0.04	0.59	FALSE
16	GTEx	Prostate	PTMA	0.62	0.08	lasso	12	0.14	3.0e-04	-6.8	-7.6	3.0e-14	0.52	0.02	0.62	FALSE
25	YFS	Blood	EIF4E2	0.06	0.04	enet	27	0.04	2.8e-13	6.9	7.2	8.0e-13	-0.02	1.00	0.00	FALSE
30	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	EFHD1	0.11	0.01	blup	70	0.03	1.0e-02	3.7	6.9	6.5e-12	-0.01	0.05	0.10	FALSE
41	The Cancer Genome Atlas	Thyroid Carcinoma	EIF4E2	0.03	0.01	blup	63	0.02	4.7e-03	6.7	-6.9	6.6e-12	0.09	0.02	0.80	FALSE
20	GTEx	Skin Sun Exposed Lower leg	RP11-690I21.1	0.08	0.05	lasso	3	0.02	3.8e-03	-6.4	6.8	1.4e-11	-0.03	0.42	0.02	FALSE
38	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	KCNJ13	0.07	0.07	blup	36	0.06	2.4e-03	-6.2	6.8	1.4e-11	0.01	0.01	0.87	FALSE
4	GTEx	Artery Tibial	EIF4E2	0.09	0.06	lasso	1	0.05	1.7e-04	6.7	-6.7	2.0e-11	0.03	0.79	0.01	FALSE
33	The Cancer Genome Atlas	Brain Lower Grade Glioma	EIF4E2	0.03	0.01	blup	60	0.02	2.7e-03	6.6	-6.7	2.3e-11	0.09	0.01	0.89	FALSE
27	The Cancer Genome Atlas	Breast Invasive Carcinoma	EIF4E2	0.03	0.03	enet	8	0.04	4.4e-08	6.7	-6.5	5.6e-11	0.03	0.02	0.98	FALSE
13	GTEx	Esophagus Mucosa	RP11-690I21.1	0.11	0.03	lasso	6	0.00	1.9e-01	-6.5	6.5	6.2e-11	-0.04	0.24	0.06	FALSE
40	The Cancer Genome Atlas	Stomach Adenocarcinoma	KCNJ13	0.09	0.06	blup	36	0.08	3.8e-06	-6.2	6.4	1.3e-10	0.01	0.01	0.98	FALSE
42	The Cancer Genome Atlas	Thyroid Carcinoma	KCNJ13	0.03	0.00	blup	35	0.01	4.3e-02	3.7	-6.4	1.3e-10	-0.01	0.01	0.59	FALSE
34	The Cancer Genome Atlas	Brain Lower Grade Glioma	GIGYF2	0.02	0.01	lasso	3	0.01	5.3e-02	-6.2	-6.3	2.5e-10	-0.02	0.04	0.82	FALSE
11	GTEx	Brain Putamen basal ganglia	C2orf82	0.28	0.22	lasso	3	0.18	5.3e-05	-5.7	6.3	2.8e-10	0.01	0.18	0.07	FALSE
28	The Cancer Genome Atlas	Breast Invasive Carcinoma	TIGD1	0.05	0.04	lasso	3	0.04	8.1e-09	6.6	-6.2	5.5e-10	0.17	0.35	0.65	FALSE
9	GTEx	Brain Frontal Cortex BA9	C2orf82	0.24	0.16	lasso	10	0.12	3.9e-04	-5.7	6.0	1.6e-09	0.02	0.56	0.02	FALSE
22	GTEx	Testis	DIS3L2	0.22	0.00	enet	16	0.00	2.1e-01	-2.9	6.0	2.4e-09	-0.07	0.06	0.05	FALSE
24	ROSMAP	Brain Pre-frontal Cortex	C2orf82	0.31	0.50	enet	24	0.50	1.3e-73	-5.7	5.9	4.4e-09	0.03	1.00	0.00	FALSE
29	The Cancer Genome Atlas	Glioblastoma Multiforme	C2orf82	0.20	0.24	lasso	8	0.20	9.1e-07	-5.7	5.8	5.9e-09	0.03	0.04	0.96	FALSE
32	The Cancer Genome Atlas	Brain Lower Grade Glioma	C2orf82	0.14	0.20	enet	6	0.19	3.1e-21	-5.7	5.8	8.3e-09	0.02	0.12	0.88	FALSE
1	CommonMind	Brain Pre-frontal Cortex	C2orf82	0.14	0.22	lasso	6	0.23	3.8e-27	-5.7	5.7	9.3e-09	0.03	1.00	0.00	FALSE
21	GTEx	Spleen	RP11-690I21.1	0.20	0.11	enet	10	0.14	1.8e-04	-4.7	5.7	1.4e-08	-0.02	0.23	0.05	FALSE
5	GTEx	Brain Caudate basal ganglia	C2orf82	0.27	0.26	lasso	1	0.24	1.2e-07	-5.7	5.7	1.6e-08	0.02	0.71	0.02	FALSE
8	GTEx	Brain Cortex	C2orf82	0.17	0.18	lasso	1	0.08	2.8e-03	-5.7	5.7	1.6e-08	0.02	0.32	0.04	FALSE
31	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	KCNJ13	0.07	0.06	enet	13	0.05	4.7e-04	-6.2	5.6	2.0e-08	0.01	0.03	0.86	FALSE
7	GTEx	Brain Cerebellum	C2orf82	0.15	0.18	lasso	2	0.13	1.1e-04	-5.7	5.6	2.7e-08	0.02	0.35	0.04	FALSE
19	GTEx	Skin Sun Exposed Lower leg	C2orf82	0.16	0.14	lasso	4	0.15	1.3e-12	-5.7	5.4	6.2e-08	0.02	1.00	0.00	FALSE
18	GTEx	Skin Not Sun Exposed Suprapubic	C2orf82	0.19	0.19	lasso	5	0.20	5.5e-11	-5.7	5.4	6.5e-08	0.03	1.00	0.00	FALSE
17	GTEx	Prostate	RP11-690I21.1	0.26	0.05	enet	36	0.04	2.9e-02	-6.5	5.4	8.0e-08	-0.11	0.08	0.11	FALSE
35	The Cancer Genome Atlas	Brain Lower Grade Glioma	NGEF	0.03	0.01	blup	130	0.01	2.0e-02	-6.2	5.2	1.7e-07	0.01	0.02	0.90	FALSE
43	The Cancer Genome Atlas	Thyroid Carcinoma	NGEF	0.04	0.03	enet	7	0.03	5.6e-04	3.7	-5.2	1.7e-07	0.00	0.04	0.92	FALSE
10	GTEx	Brain Nucleus accumbens basal ganglia	C2orf82	0.19	0.18	lasso	5	0.14	1.1e-04	-5.7	5.2	2.3e-07	0.01	0.41	0.03	FALSE