Best TWAS P=1.01e-09 · Best GWAS P=7e-09 conditioned to 0.371
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Brain Frontal Cortex BA9 | GPX1 | 0.16 | 0.06 | lasso | 6 | 0.15 | 7.9e-05 | -3.5 | -5.2 | 2.2e-07 | -0.62 | 0.02 | 0.26 | FALSE |
2 | GTEx | Breast Mammary Tissue (Female) | ARIH2 | 0.06 | 0.00 | lasso | 2 | -0.01 | 5.9e-01 | 5.8 | 6.1 | 1.0e-09 | 0.88 | 0.02 | 0.53 | TRUE |