Best TWAS P=8.37e-09 · Best GWAS P=4e-10 conditioned to 0.00175
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Cortex | PPA2 | 0.14 | 0.09 | lasso | 9 | 0.09 | 1.6e-03 | -5.3 | -5.2 | 2.5e-07 | 0.87 | 0.03 | 0.75 | FALSE |
| 2 | GTEx | Esophagus Gastroesophageal Junction | PPA2 | 0.29 | 0.15 | lasso | 5 | 0.14 | 8.8e-06 | -5.7 | -5.3 | 8.6e-08 | 0.87 | 0.02 | 0.96 | FALSE |
| 3 | GTEx | Esophagus Mucosa | PPA2 | 0.18 | 0.06 | enet | 14 | 0.12 | 2.5e-08 | 5.2 | -5.5 | 3.1e-08 | 0.71 | 0.06 | 0.93 | FALSE |
| 4 | GTEx | Ovary | PPA2 | 0.18 | 0.10 | lasso | 3 | 0.14 | 2.2e-04 | -4.2 | -5.2 | 1.7e-07 | 0.76 | 0.04 | 0.81 | FALSE |
| 5 | GTEx | Skin Sun Exposed Lower leg | TET2 | 0.09 | 0.01 | enet | 18 | 0.02 | 3.6e-03 | -6.3 | -5.8 | 8.4e-09 | 0.70 | 0.01 | 0.94 | TRUE |