[Hub]/) : Traits : Comparative height size at age 10 :

chr4:122,028,784-123,478,716

Best TWAS P=1.47e-11 · Best GWAS P=2.17e-10 conditioned to 0.121

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex BBS7 0.19 0.21 bslmm 423 0.23 1.8e-27 -6.3 -6.0 2.5e-09 0.93 0.00 1.00 FALSE
2 GTEx Brain Cerebellar Hemisphere BBS7 0.27 0.05 lasso 3 0.08 4.7e-03 -5.0 -6.0 2.3e-09 0.61 0.08 0.35 FALSE
3 GTEx Cells EBV-transformed lymphocytes EXOSC9 0.29 0.17 lasso 7 0.16 6.6e-06 5.2 5.8 8.8e-09 -0.68 0.43 0.52 FALSE
4 GTEx Cells Transformed fibroblasts BBS7 0.16 0.09 lasso 7 0.16 2.9e-12 -6.3 -6.5 8.2e-11 0.91 0.00 1.00 FALSE
5 GTEx Testis EXOSC9 0.17 0.07 lasso 8 0.10 2.5e-05 -5.0 6.1 1.3e-09 -0.87 0.01 0.98 FALSE
6 YFS Blood EXOSC9 0.06 0.09 bslmm 401 0.09 7.0e-28 5.2 5.5 3.5e-08 -0.63 0.76 0.24 FALSE
7 The Cancer Genome Atlas Breast Invasive Carcinoma EXOSC9 0.03 0.04 enet 9 0.04 2.8e-08 5.4 6.1 9.9e-10 -0.70 0.62 0.38 FALSE
8 The Cancer Genome Atlas Colon Adenocarcinoma BBS7 0.05 0.00 blup 47 0.02 1.9e-02 5.4 -5.3 1.2e-07 0.56 0.02 0.12 FALSE
9 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma CCNA2 0.03 0.01 blup 34 0.02 1.5e-03 -6.3 6.8 1.5e-11 -0.80 0.00 0.97 TRUE
10 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma BBS7 0.04 0.04 lasso 2 0.03 6.1e-04 -6.3 -6.3 2.6e-10 1.00 0.00 1.00 FALSE
11 The Cancer Genome Atlas Lung Squamous Cell Carcinoma EXOSC9 0.03 0.02 lasso 2 0.02 1.0e-03 5.1 5.8 8.5e-09 -0.66 0.09 0.28 FALSE
12 The Cancer Genome Atlas Thyroid Carcinoma EXOSC9 0.04 0.05 lasso 2 0.04 7.1e-05 5.4 6.3 3.5e-10 -0.78 0.03 0.94 FALSE