TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Maternal smoking around birth
:
→
chr10:103,550,604-105,282,664
Best TWAS P=4e-11 · Best GWAS P=1.15e-07 conditioned to 0.0302
103.6M
103.8M
104M
104.2M
104.4M
104.6M
104.8M
105M
105.2M
0
2
4
6
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
GTEx
Liver
ACTR1A
0.15
0.00
lasso
10
0.00
4.6e-01
-4.2
-6.6
4.0e-11
-0.52
0.05
0.32
TRUE
1
GTEx
Artery Coronary
CYP17A1-AS1
0.20
-0.01
enet
21
0.04
2.3e-02
1.3
5.3
9.2e-08
0.61
0.04
0.42
FALSE
3
The Cancer Genome Atlas
Bladder Urothelial Carcinoma
C10orf32
0.06
0.06
blup
54
0.08
1.2e-07
4.6
-5.1
2.7e-07
-0.74
0.04
0.94
FALSE