Best TWAS P=4e-11 · Best GWAS P=1.15e-07 conditioned to 0.0302
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Coronary | CYP17A1-AS1 | 0.20 | -0.01 | enet | 21 | 0.04 | 2.3e-02 | 1.3 | 5.3 | 9.2e-08 | 0.61 | 0.04 | 0.42 | FALSE |
| 2 | GTEx | Liver | ACTR1A | 0.15 | 0.00 | lasso | 10 | 0.00 | 4.6e-01 | -4.2 | -6.6 | 4.0e-11 | -0.52 | 0.05 | 0.32 | TRUE |
| 3 | The Cancer Genome Atlas | Bladder Urothelial Carcinoma | C10orf32 | 0.06 | 0.06 | blup | 54 | 0.08 | 1.2e-07 | 4.6 | -5.1 | 2.7e-07 | -0.74 | 0.04 | 0.94 | FALSE |