Best TWAS P=4.31e-08 · Best GWAS P=1.71e-06 conditioned to 0.679
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Breast Mammary Tissue | KLC1 | 0.12 | 0.02 | enet | 26 | 0.07 | 2.9e-04 | 4.1 | 5.3 | 1.2e-07 | -0.67 | 0.14 | 0.74 | FALSE |
| 2 | GTEx | Muscle Skeletal | KLC1 | 0.11 | 0.07 | lasso | 7 | 0.08 | 3.3e-08 | -4.7 | 5.3 | 1.5e-07 | -0.91 | 0.02 | 0.96 | FALSE |
| 3 | YFS | Blood | KLC1 | 0.01 | 0.01 | blup | 389 | 0.01 | 1.0e-03 | -4.4 | 5.5 | 4.3e-08 | -0.83 | 0.03 | 0.87 | TRUE |
| 4 | The Cancer Genome Atlas | Brain Lower Grade Glioma | C14orf153 | 0.04 | 0.01 | blup | 38 | 0.03 | 6.2e-04 | 4.2 | -5.2 | 1.8e-07 | 0.79 | 0.01 | 0.52 | FALSE |
| 5 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | CKB | 0.03 | 0.00 | blup | 34 | 0.02 | 1.4e-03 | 4.2 | -5.2 | 1.5e-07 | 0.71 | 0.01 | 0.33 | FALSE |