Best TWAS P=7.72e-11 · Best GWAS P=2.65e-12 conditioned to 0.0093
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | The Cancer Genome Atlas | Liver Hepatocellular Carcinoma | PSMA4 | 0.08 | 0.02 | blup | 40 | 0.03 | 0.01120 | -4.6 | -6.2 | 7.0e-10 | 0.83 | 0.02 | 0.57 | FALSE |
| 2 | The Cancer Genome Atlas | Ovarian Serous Cystadenocarcinoma | CHRNA5 | 0.03 | 0.01 | enet | 4 | 0.03 | 0.00206 | 3.2 | 5.1 | 2.6e-07 | -0.77 | 0.04 | 0.69 | FALSE |
| 3 | The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | CHRNA5 | 0.15 | 0.07 | blup | 50 | 0.09 | 0.00025 | -6.7 | -6.5 | 7.7e-11 | 0.95 | 0.01 | 0.97 | TRUE |